Journal of Antimicrobial Chemotherapy

ORIGINAL RESEARCH

Abstract Original research

K. Orlopp, M. von Lilienfeld-Toal, G. Marklein, S. M. Reiffert, A. Welter, C. Hahn-Ast, I. Purr, M. Gorschlüter, E. Molitor, and A. Glasmacher
False positivity of the Aspergillus galactomannan Platelia ELISA because of piperacillin/tazobactam treatment: does it represent a clinical problem?
JAC Advance Access published on July 21, 2008.
doi:10.1093/jac/dkn308
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Auxiliadora Molina, Rosa Del Campo, Luis Máiz, María-Isabel Morosini, Adelaida Lamas, Fernando Baquero, and Rafael Cantón
High prevalence in cystic fibrosis patients of multiresistant hospital-acquired methicillin-resistant Staphylococcus aureus ST228-SCCmecI capable of biofilm formation
JAC Advance Access published on July 21, 2008.
doi:10.1093/jac/dkn302
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Owe Källman, Alma Motakefi, Bengt Wretlind, Mats Kalin, Barbro Olsson-Liljequist, and Christian G. Giske
Cefuroxime non-susceptibility in multidrug-resistant Klebsiella pneumoniae overexpressing ramA and acrA and expressing ompK35 at reduced levels
JAC Advance Access published on July 21, 2008.
doi:10.1093/jac/dkn296
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Liangsu Wang, Michael K. Wismer, Fred Racine, Donald Conway, Robert A. Giacobbe, Olga Berejnaia, and Gary S. Kath
Development of an integrated semi-automated system for in vitro pharmacodynamic modelling
JAC Advance Access published on July 21, 2008.
doi:10.1093/jac/dkn294
[Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Abstract Original research

Jesús Rodríguez-Baño, Lorena López-Cerero, María D. Navarro, Paula Díaz de Alba, and Alvaro Pascual
Faecal carriage of extended-spectrum β-lactamase-producing Escherichia coli: prevalence, risk factors and molecular epidemiology
JAC Advance Access published on July 18, 2008.
doi:10.1093/jac/dkn293
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Teresa A. Takla, Sheryl A. Zelenitsky, and Lavern M. Vercaigne
Effectiveness of a 30% ethanol/4% trisodium citrate locking solution in preventing biofilm formation by organisms causing haemodialysis catheter-related infections
JAC Advance Access published on July 18, 2008.
doi:10.1093/jac/dkn291
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Pauline Byakika-Kibwika, Mohammed Lamorde, Francis Kalemeera, Antonio D'Avolio, Sciandra Mauro, Giovanni Di Perri, Mairin Ryan, Harriet Mayanja-Kizza, Saye Khoo, David Back, Marta Boffito, and Concepta Merry
Steady-state pharmacokinetic comparison of generic and branded formulations of stavudine, lamivudine and nevirapine in HIV-infected Ugandan adults
JAC Advance Access published on July 18, 2008.
doi:10.1093/jac/dkn290
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Claudine Duvivier, Jade Ghosn, Lambert Assoumou, Cathia Soulié, Gilles Peytavin, Vincent Calvez, Michèle Algarté Génin, Jean-Michel Molina, Olivier Bouchaud, Christine Katlama, Dominique Costagliola, and on behalf of the ANRS 121 study group
Initial therapy with nucleoside reverse transcriptase inhibitor-containing regimens is more effective than with regimens that spare them with no difference in short-term fat distribution: Hippocampe-ANRS 121 Trial
JAC Advance Access published on July 18, 2008.
doi:10.1093/jac/dkn278
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Evelina Tacconelli, Maria Adriana Cataldo, Gennaro De Pascale, Daniela Manno, Teresa Spanu, Andrea Cambieri, Massimo Antonelli, Maurizio Sanguinetti, Giovanni Fadda, and Roberto Cauda
Prediction models to identify hospitalized patients at risk of being colonized or infected with multidrug-resistant Acinetobacter baumannii calcoaceticus complex
JAC Advance Access published on July 17, 2008.
doi:10.1093/jac/dkn289
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Irene Yu. Lubenko, Elena V. Strukova, Maria V. Smirnova, Sergey N. Vostrov, Yury A. Portnoy, Stephen H. Zinner, and Alexander A. Firsov
Telavancin and vancomycin pharmacodynamics with Staphylococcus aureus in an in vitro dynamic model
JAC Advance Access published on July 17, 2008.
doi:10.1093/jac/dkn288
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Mateja Zorko and Roman Jerala
Alexidine and chlorhexidine bind to lipopolysaccharide and lipoteichoic acid and prevent cell activation by antibiotics
JAC Advance Access published on July 16, 2008.
doi:10.1093/jac/dkn270
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Maria S. Ramirez, T. Richard Parenteau, Daniela Centron, and Marcelo E. Tolmasky
Functional characterization of Tn1331 gene cassettes
JAC Advance Access published on July 16, 2008.
doi:10.1093/jac/dkn279
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Joanne Sanders, Alan Pithie, Peter Ganly, Lois Surgenor, Rachel Wilson, Eileen Merriman, Gail Loudon, Rhonda Judkins, and Stephen Chambers
A prospective double-blind randomized trial comparing intraluminal ethanol with heparinized saline for the prevention of catheter-associated bloodstream infection in immunosuppressed haematology patients
JAC Advance Access published on July 11, 2008.
doi:10.1093/jac/dkn284
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Stefan P. Kuster, Christian Ruef, Alfred K. Bollinger, Bruno Ledergerber, Andreas Hintermann, Clau Deplazes, Lutz Neuber, and Rainer Weber
Correlation between case mix index and antibiotic use in hospitals
JAC Advance Access published on July 9, 2008.
doi:10.1093/jac/dkn275
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Mohammed Salim Ammor, Ana Belén Flórez, Pablo Álvarez-Martín, Abelardo Margolles, and Baltasar Mayo
Analysis of tetracycline resistance tet(W) genes and their flanking sequences in intestinal Bifidobacterium species
JAC Advance Access published on July 8, 2008.
doi:10.1093/jac/dkn280
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

H. Hradecka, D. Karasova, and I. Rychlik
Characterization of Salmonella enterica serovar Typhimurium conjugative plasmids transferring resistance to antibiotics and their interaction with the virulence plasmid
JAC Advance Access published on July 7, 2008.
doi:10.1093/jac/dkn286
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Ja-Young Kim, Yeon-Joon Park, Hi Jeong Kwon, Kyungja Han, Moon Won Kang, and Gun-Jo Woo
Occurrence and mechanisms of amikacin resistance and its association with β-lactamases in Pseudomonas aeruginosa: a Korean nationwide study
JAC Advance Access published on July 7, 2008.
doi:10.1093/jac/dkn244
[Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Abstract Original research

Rachael O'Connor, Simon D. Baines, Jane Freeman, and Mark H. Wilcox
In vitro susceptibility of genotypically distinct and clonal Clostridium difficile strains to oritavancin
JAC Advance Access published on July 7, 2008.
doi:10.1093/jac/dkn276
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

David T. Bearden, George P. Allen, and J. Mark Christensen
Comparative in vitro activities of topical wound care products against community-associated methicillin-resistant Staphylococcus aureus
JAC Advance Access published on June 30, 2008.
doi:10.1093/jac/dkn272
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

José Moltó, Marta Valle, Cristina Miranda, Samandhy Cedeño, José Miranda, José Ramón Santos, Eugenia Negredo, Josep Vilaró, Joan Costa, and Bonaventura Clotet
Once- or twice-daily dosing of nevirapine in HIV-infected adults: a population pharmacokinetics approach
JAC Advance Access published on June 30, 2008.
doi:10.1093/jac/dkn268
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Michael A. Borg, Peter Zarb, Matus Ferech, Herman Goossens, and on behalf of the ARMed Project Group
Antibiotic consumption in southern and eastern Mediterranean hospitals: results from the ARMed project
JAC Advance Access published on June 30, 2008.
doi:10.1093/jac/dkn260
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Mekonnen Kurabachew, Stephen H. J. Lu, Philipp Krastel, Esther K. Schmitt, Bangalore L. Suresh, Anne Goh, John E. Knox, Ngai Ling Ma, Jan Jiricek, David Beer, Michael Cynamon, Frank Petersen, Veronique Dartois, Thomas Keller, Thomas Dick, and Vasan K. Sambandamurthy
Lipiarmycin targets RNA polymerase and has good activity against multidrug-resistant strains of Mycobacterium tuberculosis
JAC Advance Access published on June 27, 2008.
doi:10.1093/jac/dkn269
[Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Abstract Original research

C. Herzmann, Z. Cuthbertson, L. Fosdick, M. Fisher, M. Nelson, N. Perry, M. Law, H. Wand, G. Janossy, M. A. Johnson, and M. Youle
Long-term clinical and surrogate marker effects of subcutaneous intermittent interleukin-2 without antiretroviral therapy in HIV-infected patients
JAC Advance Access published on June 27, 2008.
doi:10.1093/jac/dkn238
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Shekman L. Wong, Steven L. Barriere, Michael M. Kitt, and Michael R. Goldberg
Multiple-dose pharmacokinetics of intravenous telavancin in healthy male and female subjects
JAC Advance Access published on June 26, 2008.
doi:10.1093/jac/dkn273
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Bjørg Haldorsen, Bettina Aasnaes, Kristin H. Dahl, Anne-Merethe Hanssen, Gunnar S. Simonsen, Timothy R. Walsh, Arnfinn Sundsfjord, and Eirik W. Lundblad
The AmpC phenotype in Norwegian clinical isolates of Escherichia coli is associated with an acquired ISEcp1-like ampC element or hyperproduction of the endogenous AmpC
JAC Advance Access published on June 26, 2008.
doi:10.1093/jac/dkn257
[Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Abstract Original research

Lourdes Garcia-Migura, Henrik Hasman, Christina Svendsen, and Lars Bogø Jensen
Relevance of hot spots in the evolution and transmission of Tn1546 in glycopeptide-resistant Enterococcus faecium (GREF) from broiler origin
JAC Advance Access published on June 25, 2008.
doi:10.1093/jac/dkn265
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Nahid Karami, Charles Hannoun, Ingegerd Adlerberth, and Agnes E. Wold
Colonization dynamics of ampicillin-resistant Escherichia coli in the infantile colonic microbiota
JAC Advance Access published on June 25, 2008.
doi:10.1093/jac/dkn263
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Olusegun O. Soge, Nicola K. Beck, Teresa M. White, David B. No, and Marilyn C. Roberts
A novel transposon, Tn6009, composed of a Tn916 element linked with a Staphylococcus aureus mer operon
JAC Advance Access published on June 25, 2008.
doi:10.1093/jac/dkn255
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

D. M. O'Sullivan, T. D. McHugh, and S. H. Gillespie
The effect of oxidative stress on the mutation rate of Mycobacterium tuberculosis with impaired catalase/peroxidase function
JAC Advance Access published on June 24, 2008.
doi:10.1093/jac/dkn259
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Manuel Crespo, José A. Mira, Juan A. Pineda, Eva Van den Eynde, María J. Ríos-Villegas, Antonio Collado, José A. Girón-González, Luis F. López-Cortés, Mercedes González-Serrano, Antonio Rivero, Dolores Merino, and Juan I. Esteban
Efficacy of pegylated interferon and ribavirin for retreatment of chronic HCV infection in HIV co-infected patients failing a previous standard interferon-based regimen
JAC Advance Access published on June 21, 2008.
doi:10.1093/jac/dkn262
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Inmaculada Jiménez-Nácher, Benito García, Pablo Barreiro, Sonia Rodriguez-Novoa, Judit Morello, Juan González-Lahoz, Carmen de Mendoza, and Vincent Soriano
Trends in the prescription of antiretroviral drugs and impact on plasma HIV-RNA measurements
JAC Advance Access published on June 21, 2008.
doi:10.1093/jac/dkn252
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Peter L. Anderson, Tracy King, Jia-Hua Zheng, and Samantha MaWhinney
Cytokine and sex hormone effects on zidovudine- and lamivudine-triphosphate concentrations in vitro
JAC Advance Access published on June 20, 2008.
doi:10.1093/jac/dkn247
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

N. Woodford, M. Afzal-Shah, M. Warner, and D. M. Livermore
In vitro activity of retapamulin against Staphylococcus aureus isolates resistant to fusidic acid and mupirocin
JAC Advance Access published on June 19, 2008.
doi:10.1093/jac/dkn266
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

John E. Mott, Bailin A. Shaw, James F. Smith, Paul D. Bonin, Donna L. Romero, Keith R. Marotti, and Alita A. Miller
Resistance mapping and mode of action of a novel class of antibacterial anthranilic acids: evidence for disruption of cell wall biosynthesis
JAC Advance Access published on June 19, 2008.
doi:10.1093/jac/dkn261
[Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Abstract Original research

David A. Stein, Claire Y.-H. Huang, Shawn Silengo, Adams Amantana, Stacy Crumley, Robert E. Blouch, Patrick L. Iversen, and Richard M. Kinney
Treatment of AG129 mice with antisense morpholino oligomers increases survival time following challenge with dengue 2 virus
JAC Advance Access published on June 19, 2008.
doi:10.1093/jac/dkn221
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Barira Islam, Shahper N. Khan, Irfanul Haque, M. Alam, M. Mushfiq, and Asad U. Khan
Novel anti-adherence activity of mulberry leaves: inhibition of Streptococcus mutans biofilm by 1-deoxynojirimycin isolated from Morus alba
JAC Advance Access published on June 18, 2008.
doi:10.1093/jac/dkn253
[Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Abstract Original research

Véronique Sinou, Nicolas Taudon, Joël Mosnier, Christian Aglioni, Françoise M. M. Bressolle, and Daniel Parzy
Pharmacokinetics of artesunate in the domestic pig
JAC Advance Access published on June 16, 2008.
doi:10.1093/jac/dkn231
[Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Abstract Original research

Juan-Ignacio Alós, Ana García-Cañas, Paloma García-Hierro, and Francisco Rodríguez-Salvanés
Vancomycin MICs did not creep in Staphylococcus aureus isolates from 2002 to 2006 in a setting with low vancomycin usage
JAC Advance Access published on June 13, 2008.
doi:10.1093/jac/dkn246
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Luciene A. R. Minarini, Laurent Poirel, Vincent Cattoir, Ana Lucia C. Darini, and Patrice Nordmann
Plasmid-mediated quinolone resistance determinants among enterobacterial isolates from outpatients in Brazil
JAC Advance Access published on June 13, 2008.
doi:10.1093/jac/dkn237
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Luciene M. Coelho, Roseli Aquino-Ferreira, Cláudia M. Leite Maffei, and Nilce M. Martinez-Rossi
In vitro antifungal drug susceptibilities of dermatophytes microconidia and arthroconidia
JAC Advance Access published on June 13, 2008.
doi:10.1093/jac/dkn245
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Brendan A. I. Payne, Emmanuel F. Nsutebu, Ewan R. Hunter, Olufunso Olarinde, Paul Collini, James A. T. Dunbar, Medhat S. T. Basta, James W. T. Elston, Matthias L. Schmid, Hiten Thaker, and David R. Chadwick
Low prevalence of transmitted antiretroviral drug resistance in a large UK HIV-1 cohort
JAC Advance Access published on June 13, 2008.
doi:10.1093/jac/dkn228
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Helen M. Palmer, Hugh Young, Andrew Winter, and Jayshree Dave
Emergence and spread of azithromycin-resistant Neisseria gonorrhoeae in Scotland
JAC Advance Access published on June 13, 2008.
doi:10.1093/jac/dkn235
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Diane Descamps, Lambert Assoumou, Bernard Masquelier, Anne-Geneviève Marcelin, Souhila Saidi, Catherine Tamalet, Jacqueline Cottalorda, Jean-Christophe Plantier, Brigitte Montes, Jacques Izopet, Gilles Peytavin, Sabine Yerly, Véronique Schneider, Constance Delaugerre, Virginie Ferré, Annick Ruffault, Coralie Pallier, Laurence Morand-Joubert, Marie-Laure Chaix, Vincent Calvez, Françoise Brun-Vézinet, Dominique Costagliola, and on behalf of the ANRS AC-11 Resistance Study Group
HIV-1-infected patients from the French National Observatory experiencing virological failure while receiving enfuvirtide
JAC Advance Access published on June 13, 2008.
doi:10.1093/jac/dkn225
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Anne Derache, Almoustapha-Issiaka Maiga, Ousmane Traore, Alain Akonde, Mamadou Cisse, Bernard Jarrousse, Victoria Koita, Bah Diarra, Guislaine Carcelain, Francis Barin, Cecilia Pizzocolo, Louis Pizarro, Christine Katlama, Vincent Calvez, and Anne-Genevieve Marcelin
Evolution of genetic diversity and drug resistance mutations in HIV-1 among untreated patients from Mali between 2005 and 2006
JAC Advance Access published on June 13, 2008.
doi:10.1093/jac/dkn234
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Kristina Kadlec and Stefan Schwarz
Analysis and distribution of class 1 and class 2 integrons and associated gene cassettes among Escherichia coli isolates from swine, horses, cats and dogs collected in the BfT-GermVet monitoring study
JAC Advance Access published on June 11, 2008.
doi:10.1093/jac/dkn233
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

K. L. Buising, K. A. Thursky, M. B. Robertson, J. F. Black, A. C. Street, M. J. Richards, and G. V. Brown
Electronic antibiotic stewardship—reduced consumption of broad-spectrum antibiotics using a computerized antimicrobial approval system in a hospital setting
JAC Advance Access published on June 11, 2008.
doi:10.1093/jac/dkn218
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

David S. Y. Ong, Marijke M. Kuyvenhoven, Liset van Dijk, and Theo J. M. Verheij
Antibiotics for respiratory, ear and urinary tract disorders and consistency among GPs
JAC Advance Access published on June 10, 2008.
doi:10.1093/jac/dkn230
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

G. A. Lamaris, R. Ben-Ami, R. E. Lewis, and D. P. Kontoyiannis
Does pre-exposure of Aspergillus fumigatus to voriconazole or posaconazole in vitro affect its virulence and the in vivo activity of subsequent posaconazole or voriconazole, respectively? A study in a fly model of aspergillosis
JAC Advance Access published on June 10, 2008.
doi:10.1093/jac/dkn224
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Pratibha Tiwari, Divya Singh, and Man Mohan Singh
Anti-Trichomonas activity of Sapindus saponins, a candidate for development as microbicidal contraceptive
JAC Advance Access published on June 10, 2008.
doi:10.1093/jac/dkn223
[Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Abstract Original research

Sébastien Van de Velde, Hoang Anh Nguyen, Françoise Van Bambeke, Paul M. Tulkens, Jean Grellet, Véronique Dubois, Claudine Quentin, and Marie-Claude Saux
Contrasting effects of human THP-1 cell differentiation on levofloxacin and moxifloxacin intracellular accumulation and activity against Staphylococcus aureus and Listeria monocytogenes
JAC Advance Access published on June 10, 2008.
doi:10.1093/jac/dkn232
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Linus Sandegren, Anton Lindqvist, Gunnar Kahlmeter, and Dan I. Andersson
Nitrofurantoin resistance mechanism and fitness cost in Escherichia coli
JAC Advance Access published on June 10, 2008.
doi:10.1093/jac/dkn222
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

L. J. Wheeldon, T. Worthington, P. A. Lambert, A. C. Hilton, C. J. Lowden, and T. S. J. Elliott
Antimicrobial efficacy of copper surfaces against spores and vegetative cells of Clostridium difficile: the germination theory
JAC Advance Access published on June 10, 2008.
doi:10.1093/jac/dkn219
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Jürgen Barth, Doris Jäger, Ralf Mundkowski, Bernd Drewelow, Tobias Welte, and Olaf Burkhardt
Single- and multiple-dose pharmacokinetics of intravenous moxifloxacin in patients with severe hepatic impairment
JAC Advance Access published on May 30, 2008.
doi:10.1093/jac/dkn212
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Isabel Couto, Sofia Santos Costa, Miguel Viveiros, Marta Martins, and Leonard Amaral
Efflux-mediated response of Staphylococcus aureus exposed to ethidium bromide
JAC Advance Access published on May 28, 2008.
doi:10.1093/jac/dkn217
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Raquel Villar, Esther Vicente, Beatriz Solano, Silvia Pérez-Silanes, Ignacio Aldana, Joseph A. Maddry, Anne J. Lenaerts, Scott G. Franzblau, Sang-Hyun Cho, Antonio Monge, and Robert C. Goldman
In vitro and in vivo antimycobacterial activities of ketone and amide derivatives of quinoxaline 1,4-di-N-oxide
JAC Advance Access published on May 23, 2008.
doi:10.1093/jac/dkn214
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Mery Ruíz-Cendoya, Marçal Mariné, and Josep Guarro
Combined therapy in treatment of murine infection by Fusarium solani
JAC Advance Access published on May 20, 2008.
doi:10.1093/jac/dkn215
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Gérard Moulin, Philippe Cavalié, Isabelle Pellanne, Anne Chevance, Arlette Laval, Yves Millemann, Pierre Colin, Claire Chauvin, and on behalf of the ‘Antimicrobial Resistance’ ad hoc Group of the French Food Safety Agency
A comparison of antimicrobial usage in human and veterinary medicine in France from 1999 to 2005
JAC Advance Access published on May 19, 2008.
doi:10.1093/jac/dkn213
[Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Abstract Original research

A. R. Vieira, S. Wu, L. B. Jensen, A. Dalsgaard, H. Houe, H. C. Wegener, D. M. A. Lo Fo Wong, and H.-D. Emborg
Using data on resistance prevalence per sample in the surveillance of antimicrobial resistance
JAC Advance Access published on May 19, 2008.
doi:10.1093/jac/dkn210
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Jann-Tay Wang, Wang-Huei Sheng, Jiun-Ling Wang, Duckling Chen, Mei-Ling Chen, Yee-Chun Chen, and Shan-Chwen Chang
Longitudinal analysis of chlorhexidine susceptibilities of nosocomial methicillin-resistant Staphylococcus aureus isolates at a teaching hospital in Taiwan
JAC Advance Access published on May 13, 2008.
doi:10.1093/jac/dkn208
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Alexandr Nemec, Lenka Krízová, Martina Maixnerová, Laure Diancourt, Tanny J. K. van der Reijden, Sylvain Brisse, Peterhans van den Broek, and Lenie Dijkshoorn
Emergence of carbapenem resistance in Acinetobacter baumannii in the Czech Republic is associated with the spread of multidrug-resistant strains of European clone II
JAC Advance Access published on May 13, 2008.
doi:10.1093/jac/dkn205
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Nils von Hentig, Errol Babacan, Tessa Lennemann, Gabi Knecht, Amina Carlebach, Sebastian Harder, Schlomo Staszewski, and Annette Haberl
The steady-state pharmacokinetics of atazanavir/ritonavir in HIV-1-infected adult outpatients is not affected by gender-related co-factors
JAC Advance Access published on May 13, 2008.
doi:10.1093/jac/dkn204
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Nathalie Vernaz, Hugo Sax, Didier Pittet, Pascal Bonnabry, Jacques Schrenzel, and Stephan Harbarth
Temporal effects of antibiotic use and hand rub consumption on the incidence of MRSA and Clostridium difficile
JAC Advance Access published on May 8, 2008.
doi:10.1093/jac/dkn199
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Original research

Mamoon A. Aldeyab, Dominique L. Monnet, José María López-Lozano, Carmel M. Hughes, Michael G. Scott, Mary P. Kearney, Fidelma A. Magee, and James C. McElnay
Modelling the impact of antibiotic use and infection control practices on the incidence of hospital-acquired methicillin-resistant Staphylococcus aureus: a time-series analysis
JAC Advance Access published on May 7, 2008.
doi:10.1093/jac/dkn198
[Abstract] [Full Text] [PDF] [Request Permissions]  

RESEARCH LETTER

Research letter

Zhaoliang Su, Xiaoli Dai, Jianguo Chen, Fanzhi Kong, Huifang Wang, Yazhen Li, Sufang Peng, Shengjun Wang, Qixiang Shao, Liwe Lv, and Huaxi Xu
The bla_CTX-M-1 gene located in a novel complex class I integron bearing an ISCR1 element in Escherichia coli isolates from Zhenjiang, China
JAC Advance Access published on July 21, 2008.
doi:10.1093/jac/dkn300
[Extract] [Full Text] [PDF] [Request Permissions]  

Research letter

Shellee A. Grim, Lisa Rene, Sandeep Gupta, and Nina M. Clark
Safety of linezolid in patients with baseline thrombocytopenia
JAC Advance Access published on July 2, 2008.
doi:10.1093/jac/dkn285
[Extract] [Full Text] [PDF] [Request Permissions]  

Research letter

E. Botelho-Nevers, Leon Espinosa, D. Raoult, and J.-M. Rolain
Lovastatin, but not pravastatin, limits in vitro infection due to Coxiella burnetii
JAC Advance Access published on June 30, 2008.
doi:10.1093/jac/dkn282
[Extract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Research letter

Yvonne Agersø, Camilla H. Lester, Lone J. Porsbo, Iben Ørsted, Hanne-Dorthe Emborg, Katharina E. P. Olsen, Lars B. Jensen, Ole E. Heuer, Niels Frimodt-Møller, Frank M. Aarestrup, and Anette M. Hammerum
Vancomycin-resistant Enterococcus faecalis isolates from a Danish patient and two healthy human volunteers are possibly related to isolates from imported turkey meat
JAC Advance Access published on June 26, 2008.
doi:10.1093/jac/dkn271
[Extract] [Full Text] [PDF] [Request Permissions]  

Research letter Visanu Thamlikitkul and Surapee Tiengrim Effect of different Mueller–Hinton agars on tigecycline disc diffusion susceptibility for Acinetobacter spp. JAC Advance Access published on June 21, 2008. doi:10.1093/jac/dkn267 [Extract] [Full Text] [PDF]     OPEN ACCESS ARTICLE

Research letter

Amy Gassama Sow, Mamadou Hadi Diallo, Martine Gatet, François Denis, Awa Aïdara-Kane, and Marie-Cécile Ploy
Description of an unusual class 2 integron in Shigella sonnei isolates in Senegal (sub-Saharan Africa)
JAC Advance Access published on June 18, 2008.
doi:10.1093/jac/dkn264
[Extract] [Full Text] [PDF] [Request Permissions]  

Research letter

Julie Bresson, Catherine Paugam-Burtz, Julien Josserand, Christophe Bardin, Jean Mantz, and Sebastian Pease
Cefepime overdosage with neurotoxicity recovered by high-volume haemofiltration
JAC Advance Access published on June 18, 2008.
doi:10.1093/jac/dkn256
[Extract] [Full Text] [PDF] [Request Permissions]  

Research letter

Naveed Ahmed Khan, Khadijo Osman, and Graham John Goldsworthy
Lysates of Locusta migratoria brain exhibit potent broad-spectrum antibacterial activity
JAC Advance Access published on June 13, 2008.
doi:10.1093/jac/dkn239
[Extract] [Full Text] [PDF] [Request Permissions]  

Research letter

Eva Tzelepi, Maria Daniilidou, Vivi Miriagou, Eirini Siatravani, Efthimia Pavlidou, and Alexandros Flemetakis
Cluster of multidrug-resistant Neisseria gonorrhoeae with reduced susceptibility to the newer cephalosporins in Northern Greece
JAC Advance Access published on June 12, 2008.
doi:10.1093/jac/dkn236
[Extract] [Full Text] [PDF] [Request Permissions]  

Research letter

Vicki Ann Luna, Ze-Qi Xu, David A. Eiznhamer, Andrew C. Cannons, and Jacqueline Cattani
Susceptibility of 170 isolates of the USA300 clone of MRSA to macrolides, clindamycin and the novel ketolide cethromycin
JAC Advance Access published on June 10, 2008.
doi:10.1093/jac/dkn227
[Extract] [Full Text] [PDF] [Request Permissions]  

Research letter

L. M. Cavaco, H. Korsgaard, G. Sørensen, and F. M. Aarestrup
Plasmid-mediated quinolone resistance due to qnrB5 and qnrS1 genes in Salmonella enterica serovars Newport, Hadar and Saintpaul isolated from turkey meat in Denmark
JAC Advance Access published on May 20, 2008.
doi:10.1093/jac/dkn211
[Extract] [Full Text] [PDF] [Request Permissions]  

Research letter

H. Sandovsky-Losica, R. Shwartzman, Y. Lahat, and E. Segal
Antifungal activity against Candida albicans of nikkomycin Z in combination with caspofungin, voriconazole or amphotericin B
JAC Advance Access published on May 19, 2008.
doi:10.1093/jac/dkn216
[Extract] [Full Text] [PDF] [Request Permissions]  

Research letter

M. Habibur Rahman, Kentaro Q. Sakamoto, Lisa Nonaka, and Satoru Suzuki
Occurrence and diversity of the tetracycline resistance gene tet(M) in enteric bacteria of Antarctic Adélie penguins
JAC Advance Access published on May 16, 2008.
doi:10.1093/jac/dkn209
[Extract] [Full Text] [PDF] [Request Permissions]  

Research letter

Dóra Szabó, Béla Kocsis, László Rókusz, Júlia Szentandrássy, Katalin Katona, Katalin Kristóf, and Károly Nagy
First detection of plasmid-mediated, quinolone resistance determinants qnrA, qnrB, qnrS and aac(6')-Ib-cr in extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae in Budapest, Hungary
JAC Advance Access published on May 13, 2008.
doi:10.1093/jac/dkn206
[Extract] [Full Text] [PDF] [Request Permissions]  

Research letter

Tamara Kastrin, Marija Gubina, Metka Paragi, Jana Kolman, Milan Cizman, Alenka Kraigher, Helena Ribic, Ewa Sadowy, and Waleria Hryniewicz
Macrolide resistance among invasive Streptococcus pneumoniae in Slovenia
JAC Advance Access published on May 12, 2008.
doi:10.1093/jac/dkn202
[Extract] [Full Text] [PDF] [Request Permissions]  

Research Letter

Marcelle Bottecchia, Antonio Madejón, Julie Sheldon, Javier García-Samaniego, Pablo Barreiro, and Vincent Soriano
Hepatitis B virus genotype A2 harbours an L217R polymorphism which may account for a lower response to adefovir
JAC Advance Access published on May 8, 2008.
doi:10.1093/jac/dkn207
[Extract] [Full Text] [PDF] [Request Permissions]  

SYSTEMATIC REVIEW

Abstract Systematic review

Ilias I. Siempos, Konstantinos Z. Vardakas, Petros Kopterides, and Matthew E. Falagas
Adjunctive therapies for community-acquired pneumonia: a systematic review
JAC Advance Access published on July 18, 2008.
doi:10.1093/jac/dkn283
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Systematic review

Matthew E. Falagas, Sofia G. Avgeri, Dimitrios K. Matthaiou, George Dimopoulos, and Ilias I. Siempos
Short- versus long-duration antimicrobial treatment for exacerbations of chronic bronchitis: a meta-analysis
JAC Advance Access published on May 8, 2008.
doi:10.1093/jac/dkn201
[Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

LEADING ARTICLE

Abstract Leading article

Anna Maria Geretti
Shifting paradigms: the resistance profile of etravirine
JAC Advance Access published on June 19, 2008.
doi:10.1093/jac/dkn248
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Leading article

Samson S. Y. Wong and Kwok-Yung Yuen
The management of coronavirus infections with particular reference to SARS
JAC Advance Access published on June 18, 2008.
doi:10.1093/jac/dkn243
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Leading article

S. Harbarth and M. H. Samore
Interventions to control MRSA: high time for time-series analysis?
JAC Advance Access published on June 12, 2008.
doi:10.1093/jac/dkn240
[Abstract] [Full Text] [PDF] [Request Permissions]  

Abstract Leading article

Xilin Zhao and Karl Drlica
A unified anti-mutant dosing strategy
JAC Advance Access published on June 10, 2008.
doi:10.1093/jac/dkn229
[Abstract] [Full Text] [PDF] [Request Permissions]  

REVIEW

Abstract Review

Jane E. Mallewa, Edmund Wilkins, Javier Vilar, Macpherson Mallewa, Dominic Doran, David Back, and Munir Pirmohamed
HIV-associated lipodystrophy: a