Journal of Antimicrobial Chemotherapy

Leading articles

Get checked abstract Matthew Dryden, Kieran Hand, Peter Davey, and on behalf of the BSAC Council

Antibiotics for community-acquired pneumonia
JAC Advance Access published on October 10, 2009
J. Antimicrob. Chemother. 2009 64: 1123-1125; doi:10.1093/jac/dkp359 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Asgeir Johannessen, Marius Trøseid, and Alexandra Calmy

Dried blood spots can expand access to virological monitoring of HIV treatment in resource-limited settings
JAC Advance Access published on September 23, 2009
J. Antimicrob. Chemother. 2009 64: 1126-1129; doi:10.1093/jac/dkp353 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Review

Get checked abstract Judith N. Steenbergen, John F. Mohr, and Grace M. Thorne

Effects of daptomycin in combination with other antimicrobial agents: a review of in vitro and animal model studies
JAC Advance Access published on October 12, 2009
J. Antimicrob. Chemother. 2009 64: 1130-1138; doi:10.1093/jac/dkp346 [Abstract] [Full Text] [PDF] [Request Permissions]  

Systematic review

Get checked abstract José A. Pérez-Molina, Ana Pérez-Ayala, Santiago Moreno, M. Carmen Fernández-González, Javier Zamora, and Rogelio López-Velez

Use of benznidazole to treat chronic Chagas' disease: a systematic review with a meta-analysis
JAC Advance Access published on October 9, 2009
J. Antimicrob. Chemother. 2009 64: 1139-1147; doi:10.1093/jac/dkp357 [Abstract] [Full Text] [PDF] [Request Permissions]  

Original research

Get checked abstract Olusegun O. Soge, John S. Meschke, David B. No, and Marilyn C. Roberts

Characterization of methicillin-resistant Staphylococcus aureus and methicillin-resistant coagulase-negative Staphylococcus spp. isolated from US West Coast public marine beaches
JAC Advance Access published on October 16, 2009
J. Antimicrob. Chemother. 2009 64: 1148-1155; doi:10.1093/jac/dkp368 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Kristina Kadlec, Ralf Ehricht, Stefan Monecke, Ulrike Steinacker, Heike Kaspar, Joachim Mankertz, and Stefan Schwarz

Diversity of antimicrobial resistance pheno- and genotypes of methicillin-resistant Staphylococcus aureus ST398 from diseased swine
JAC Advance Access published on September 25, 2009
J. Antimicrob. Chemother. 2009 64: 1156-1164; doi:10.1093/jac/dkp350 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Elia Gómez G. de la Pedrosa, Fernando Baquero, Elena Loza, José-María Nadal-Serrano, Asunción Fenoll, Rosa del Campo, and Rafael Cantón

High clonal diversity in erythromycin-resistant Streptococcus pneumoniae invasive isolates in Madrid, Spain (2000–07)
JAC Advance Access published on October 16, 2009
J. Antimicrob. Chemother. 2009 64: 1165-1169; doi:10.1093/jac/dkp364 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Corinna Kehrenberg, Axel Cloeckaert, Günter Klein, and Stefan Schwarz

Decreased fluoroquinolone susceptibility in mutants of Salmonella serovars other than Typhimurium: detection of novel mutations involved in modulated expression of ramA and soxS
JAC Advance Access published on September 23, 2009
J. Antimicrob. Chemother. 2009 64: 1175-1180; doi:10.1093/jac/dkp347 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Rubén González-Sanz, Silvia Herrera-León, Manuela de la Fuente, Margarita Arroyo, and M. Aurora Echeita

Emergence of extended-spectrum β-lactamases and AmpC-type β-lactamases in human Salmonella isolated in Spain from 2001 to 2005
JAC Advance Access published on October 8, 2009
J. Antimicrob. Chemother. 2009 64: 1181-1186; doi:10.1093/jac/dkp361 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Joachim Müller, Dorothea Nillius, Adrian Hehl, Andrew Hemphill, and Norbert Müller

Stable expression of Escherichia coli β-glucuronidase A (GusA) in Giardia lamblia: application to high-throughput drug susceptibility testing
JAC Advance Access published on October 10, 2009
J. Antimicrob. Chemother. 2009 64: 1187-1191; doi:10.1093/jac/dkp363 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Mohammad-Ali Jenabian, Héla Saïdi, Charlotte Charpentier, Yven Van Herrewege, Jong Chan Son, Dominique Schols, Jan Balzarini, Guido Vanham, and Laurent Bélec on behalf of the ANRS Multi-Micro Project Study Group

In vitro synergistic activity against CCR5-tropic HIV-1 with combinations of potential candidate microbicide molecules HHA, KRV2110 and enfuvirtide (T20)
JAC Advance Access published on October 29, 2009
J. Antimicrob. Chemother. 2009 64: 1192-1195; doi:10.1093/jac/dkp380 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Alain Bizzini, Chen Zhao, Yanick Auffray, and Axel Hartke

The Enterococcus faecalis superoxide dismutase is essential for its tolerance to vancomycin and penicillin
JAC Advance Access published on October 14, 2009
J. Antimicrob. Chemother. 2009 64: 1196-1202; doi:10.1093/jac/dkp369 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Sasitorn Chusri, Ivan Villanueva, Supayang Piyawan Voravuthikunchai, and Julian Davies

Enhancing antibiotic activity: a strategy to control Acinetobacter infections
JAC Advance Access published on October 27, 2009
J. Antimicrob. Chemother. 2009 64: 1203-1211; doi:10.1093/jac/dkp381 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Vivek Verma, Kusum Harjai, and Sanjay Chhibber

Restricting ciprofloxacin-induced resistant variant formation in biofilm of Klebsiella pneumoniae B5055 by complementary bacteriophage treatment
JAC Advance Access published on October 4, 2009
J. Antimicrob. Chemother. 2009 64: 1212-1218; doi:10.1093/jac/dkp360 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract E. R. Hendry, T. Worthington, B. R. Conway, and P. A. Lambert

Antimicrobial efficacy of eucalyptus oil and 1,8-cineole alone and in combination with chlorhexidine digluconate against microorganisms grown in planktonic and biofilm cultures
JAC Advance Access published on October 16, 2009
J. Antimicrob. Chemother. 2009 64: 1219-1225; doi:10.1093/jac/dkp362 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Yen-Hsu Chen, Chia-Ying Liu, Jang-Jih Lu, Chi-Hsin R. King, and Po-Ren Hsueh

In vitro activity of nemonoxacin (TG-873870), a novel non-fluorinated quinolone, against clinical isolates of Staphylococcus aureus, enterococci and Streptococcus pneumoniae with various resistance phenotypes in Taiwan
JAC Advance Access published on October 14, 2009
J. Antimicrob. Chemother. 2009 64: 1226-1229; doi:10.1093/jac/dkp370 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Luis Alou, María-José Giménez, Fabio Cafini, Lorenzo Aguilar, David Sevillano, Natalia González, Martha Torrico, José Prieto, César García-Rey, and Nuria García-Escribano

In vitro effect of physiological concentrations of human albumin on the antibacterial activity of tigecycline
JAC Advance Access published on October 16, 2009
J. Antimicrob. Chemother. 2009 64: 1230-1233; doi:10.1093/jac/dkp371 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Marta Gontijo Aguiar, Diana Lara Silva, Fernando Antônio Nunan, Elzíria Aguiar Nunan, Ana Paula Fernandes, and Lucas Antônio Miranda Ferreira

Combined topical paromomycin and oral miltefosine treatment of mice experimentally infected with Leishmania (Leishmania) major leads to reduction in both lesion size and systemic parasite burdens
JAC Advance Access published on October 12, 2009
J. Antimicrob. Chemother. 2009 64: 1234-1240; doi:10.1093/jac/dkp365 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Maria van Gennip, Claus Moser, Louise D. Christensen, Thomas Bjarnsholt, Henrik Calum, Peter Ø. Jensen, Lars Christophersen, Hans Petter Hougen, Oana Ciofu, Søren Molin, Michael Givskov, and Niels Høiby

Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa
JAC Advance Access published on October 8, 2009
J. Antimicrob. Chemother. 2009 64: 1241-1250; doi:10.1093/jac/dkp352 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Louisa Pollock, Laura Else, Goenke Poerksen, Elizabeth Molyneux, Peter Moons, Sarah Walker, William Fraser, David Back, and Saye Khoo

Pharmacokinetics of nevirapine in HIV-infected children with and without malnutrition receiving divided adult fixed-dose combination tablets
JAC Advance Access published on October 6, 2009
J. Antimicrob. Chemother. 2009 64: 1251-1259; doi:10.1093/jac/dkp358 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract M. Bickel, A. Bodtländer, G. K. Knecht, C. Stephan, N. von Hentig, M. Kurowski, P. Gute, S. Klauke, and T. Lutz

Once-daily treatment with saquinavir mesylate (2000 mg) and ritonavir (100 mg) together with a fixed-dose combination of abacavir/lamivudine (600/300 mg) or tenofovir/emtricitabine (245/200 mg) in HIV-1-infected patients
JAC Advance Access published on September 22, 2009
J. Antimicrob. Chemother. 2009 64: 1260-1264; doi:10.1093/jac/dkp348 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Soranun Chantarangsu, Tim R. Cressey, Surakameth Mahasirimongkol, Edmund Capparelli, Yardpiroon Tawon, Nicole Ngo-Giang-Huong, Gonzague Jourdain, Marc Lallemant, and Wasun Chantratita

Influence of CYP2B6 polymorphisms on the persistence of plasma nevirapine concentrations following a single intra-partum dose for the prevention of mother to child transmission in HIV-infected Thai women
JAC Advance Access published on October 6, 2009
J. Antimicrob. Chemother. 2009 64: 1265-1273; doi:10.1093/jac/dkp351 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract C. Viscoli, R. Herbrecht, H. Akan, L. Baila, A. Sonet, A. Gallamini, A. Giagounidis, O. Marchetti, R. Martino, L. Meert, M. Paesmans, L. Ameye, M. Shivaprakash, A. J. Ullmann, J. Maertens, and on behalf of the Infectious Disease Group of the EORTC

An EORTC Phase II study of caspofungin as first-line therapy of invasive aspergillosis in haematological patients
JAC Advance Access published on October 19, 2009
J. Antimicrob. Chemother. 2009 64: 1274-1281; doi:10.1093/jac/dkp355 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Jannik Helweg-Larsen, Thomas Benfield, Chiara Atzori, and Robert F. Miller

Clinical efficacy of first- and second-line treatments for HIV-associated Pneumocystis jirovecii pneumonia: a tri-centre cohort study
JAC Advance Access published on October 26, 2009
J. Antimicrob. Chemother. 2009 64: 1282-1290; doi:10.1093/jac/dkp372 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Stephen G. Weber, Ram R. Miller, Eli N. Perencevich, Jocelyn Tolentino, David Meltzer, David Pitrak, Jessina C. McGregor, Greg A. Sachs, Anthony D. Harris, and Jon P. Furuno

Prevalence of antimicrobial-resistant bacteria isolated from older versus younger hospitalized adults: results of a two-centre study
JAC Advance Access published on September 24, 2009
J. Antimicrob. Chemother. 2009 64: 1291-1298; doi:10.1093/jac/dkp349 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Olivier Denis, Bea Jans, Ariane Deplano, Claire Nonhoff, Raf De Ryck, Carl Suetens, and Marc J. Struelens

Epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) among residents of nursing homes in Belgium
JAC Advance Access published on September 24, 2009
J. Antimicrob. Chemother. 2009 64: 1299-1306; doi:10.1093/jac/dkp345 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Katiuska Miliani, François L'Hériteau, Pascal Astagneau, and on behalf of the INCISO Network Study Group

Non-compliance with recommendations for the practice of antibiotic prophylaxis and risk of surgical site infection: results of a multilevel analysis from the INCISO Surveillance Network
JAC Advance Access published on October 16, 2009
J. Antimicrob. Chemother. 2009 64: 1307-1315; doi:10.1093/jac/dkp367 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Ann L. N. Chapman, Simon Dixon, Dawn Andrews, Patrick J. Lillie, Rohit Bazaz, and Julie D. Patchett

Clinical efficacy and cost-effectiveness of outpatient parenteral antibiotic therapy (OPAT): a UK perspective
JAC Advance Access published on September 19, 2009
J. Antimicrob. Chemother. 2009 64: 1316-1324; doi:10.1093/jac/dkp343 [Abstract] [Full Text] [PDF] [Request Permissions]  

Research letters

Carmen Lozano, María López, Elena Gómez-Sanz, Fernanda Ruiz-Larrea, Carmen Torres, and Myriam Zarazaga

Detection of methicillin-resistant Staphylococcus aureus ST398 in food samples of animal origin in Spain
JAC Advance Access published on October 21, 2009
J. Antimicrob. Chemother. 2009 64: 1325-1326; doi:10.1093/jac/dkp378 [Extract] [Full Text] [PDF] [Request Permissions]  

Noriyuki Nagano, Kouji Kimura, Yukiko Nagano, Hiroaki Yakumaru, and Yoshichika Arakawa

Molecular characterization of group B streptococci with reduced penicillin susceptibility recurrently isolated from a sacral decubitus ulcer
JAC Advance Access published on October 16, 2009
J. Antimicrob. Chemother. 2009 64: 1326-1328; doi:10.1093/jac/dkp374 [Extract] [Full Text] [PDF] [Request Permissions]  

Xiang-Dang Du, Cong-Ming Wu, He-Bing Liu, Xin-Sheng Li, Ross C. Beier, Fang Xiao, Shang-Shang Qin, Si-Yang Huang, and Jian-Zhong Shen

Plasmid-mediated ArmA and RmtB 16S rRNA methylases in Escherichia coli isolated from chickens
JAC Advance Access published on September 26, 2009
J. Antimicrob. Chemother. 2009 64: 1328-1330; doi:10.1093/jac/dkp354 [Extract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Mushtaq A. Khan, Nicole Lemmens, Esteban Riera, Tamara Blonk, Janet Goedhart, Alex Van Belkum, Wil Goessens, John P. Hays, and Mireille Van Westreenen

Dominance of CTX-M-2 and CTX-M-56 among extended-spectrum β-lactamases produced by Klebsiella pneumoniae and Escherichia coli isolated in hospitals in Paraguay
JAC Advance Access published on October 23, 2009
J. Antimicrob. Chemother. 2009 64: 1330-1332; doi:10.1093/jac/dkp382 [Extract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Daniela Fortini, Aurora García-Fernández, Kees Veldman, Dik Mevius, and Alessandra Carattoli

Novel genetic environment of plasmid-mediated quinolone resistance gene qnrB2 in Salmonella Bredeney from poultry
JAC Advance Access published on September 29, 2009
J. Antimicrob. Chemother. 2009 64: 1332-1334; doi:10.1093/jac/dkp356 [Extract] [Full Text] [PDF] [Request Permissions]  

Belén Gutierrez, Silvia Herrera-Leon, José Antonio Escudero, Laura Hidalgo, Rubén Gonzalez-Sanz, Margarita Arroyo, Álvaro San Millan, María Aurora Echeita, and Bruno Gonzalez-Zorn

Novel genetic environment of qnrB2 associated with TEM-1 and SHV-12 on pB1004, an IncHI2 plasmid, in Salmonella Bredeney BB1047 from Spain
JAC Advance Access published on September 22, 2009
J. Antimicrob. Chemother. 2009 64: 1334-1336; doi:10.1093/jac/dkp340 [Extract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Shilpakala Sainath Rao and Malathi Raghunathan

In vitro activity of the new quinolone derivative RD-3 against clinical isolates of Mycoplasma pneumoniae and Mycoplasma hominis
JAC Advance Access published on October 21, 2009
J. Antimicrob. Chemother. 2009 64: 1336-1338; doi:10.1093/jac/dkp375 [Extract] [Full Text] [PDF] [Request Permissions]  

Asunción Fenoll, María-José Giménez, María-Dolores Vicioso, Juan-José Granizo, Olga Robledo, and Lorenzo Aguilar

Susceptibility of pneumococci causing meningitis in Spain and prevalence among such isolates of serotypes contained in the 7-valent pneumococcal conjugate vaccine
JAC Advance Access published on October 14, 2009
J. Antimicrob. Chemother. 2009 64: 1338-1340; doi:10.1093/jac/dkp376 [Extract] [Full Text] [PDF] [Request Permissions]  

Ming Lim, Esse Menson, C. Y. William Tong, and Jean-Pierre Lin

Use of therapeutic drug monitoring in the long-term valaciclovir therapy of relapsing herpes simplex virus encephalitis in children
JAC Advance Access published on October 14, 2009
J. Antimicrob. Chemother. 2009 64: 1340-1341; doi:10.1093/jac/dkp373 [Extract] [Full Text] [PDF] [Request Permissions]  

Mona Loutfy, Esteban Ribera, Eric Florence, Stéphane De Wit, Antonella Castagna, Robert Ryan, Andrew Hill, Hilde Vanaken, Yvonne van Delft, and Stephan Marks

Sustained HIV RNA suppression after switching from enfuvirtide to etravirine in the early access programme
JAC Advance Access published on October 14, 2009
J. Antimicrob. Chemother. 2009 64: 1341-1344; doi:10.1093/jac/dkp366 [Extract] [Full Text] [PDF] [Request Permissions]  

Daniel Curcio

Off-label use of antibiotics in hospitalized patients: focus on tigecycline
JAC Advance Access published on September 16, 2009
J. Antimicrob. Chemother. 2009 64: 1344-1346; doi:10.1093/jac/dkp342 [Extract] [Full Text] [PDF] [Request Permissions]  

Letter to the Editor

Niels Adriaenssens, Herman Goossens, and Samuel Coenen on behalf of the ESAC Project Group

Comment on: Developments in outpatient parenteral antimicrobial therapy (OPAT) for Gram-positive infections in Europe, and the potential impact of daptomycin
JAC Advance Access published on October 19, 2009
J. Antimicrob. Chemother. 2009 64: 1347; doi:10.1093/jac/dkp379 [Extract] [Full Text] [PDF] [Request Permissions]  

Acknowledgement to referees

Acknowledgement to referees
J. Antimicrob. Chemother. 2009 64: 1348-1353; doi:10.1093/jac/dkp405 [Extract] [Full Text] [PDF] [Request Permissions]  

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