Journal of Antimicrobial Chemotherapy

Leading article

Get checked abstract Giovanni Guaraldi and Ioannis G. Baraboutis

Evolving perspectives on HIV-associated lipodystrophy syndrome: moving from lipodystrophy to non-infectious HIV co-morbidities
JAC Advance Access published on July 3, 2009
J. Antimicrob. Chemother. 2009 64: 437-440; doi:10.1093/jac/dkp240 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Reviews

Get checked abstract Fred C. Tenover and Richard V. Goering

Methicillin-resistant Staphylococcus aureus strain USA300: origin and epidemiology
JAC Advance Access published on July 16, 2009
J. Antimicrob. Chemother. 2009 64: 441-446; doi:10.1093/jac/dkp241 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Dilip Nathwani

Developments in outpatient parenteral antimicrobial therapy (OPAT) for Gram-positive infections in Europe, and the potential impact of daptomycin
JAC Advance Access published on July 7, 2009
J. Antimicrob. Chemother. 2009 64: 447-453; doi:10.1093/jac/dkp245 [Abstract] [Full Text] [PDF] [Request Permissions]  

Original research

Get checked abstract J. M. Andrews for the BSAC Working Party on Susceptibility Testing

BSAC standardized disc susceptibility testing method (version 8)
JAC Advance Access published on July 8, 2009
J. Antimicrob. Chemother. 2009 64: 454-489; doi:10.1093/jac/dkp244 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Lisbeth Elvira de Vries, Henrik Christensen, Robert L. Skov, Frank M. Aarestrup, and Yvonne Agersø

Diversity of the tetracycline resistance gene tet(M) and identification of Tn916- and Tn5801-like (Tn6014) transposons in Staphylococcus aureus from humans and animals
JAC Advance Access published on June 16, 2009
J. Antimicrob. Chemother. 2009 64: 490-500; doi:10.1093/jac/dkp214 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Akihiro Tazumi, Yasunori Maeda, Colin E. Goldsmith, Wilson A. Coulter, Charlene Mason, B. Cherie Millar, Mark McCalmont, Jackie Rendall, J. Stuart Elborn, Motoo Matsuda, and John E. Moore

Molecular characterization of macrolide resistance determinants [erm(B) and mef(A)] in Streptococcus pneumoniae and viridans group streptococci (VGS) isolated from adult patients with cystic fibrosis (CF)
JAC Advance Access published on July 7, 2009
J. Antimicrob. Chemother. 2009 64: 501-506; doi:10.1093/jac/dkp213 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Carmen Ardanuy, Dora Rolo, Asunción Fenoll, David Tarrago, Laura Calatayud, and Josefina Liñares

Emergence of a multidrug-resistant clone (ST320) among invasive serotype 19A pneumococci in Spain
JAC Advance Access published on June 17, 2009
J. Antimicrob. Chemother. 2009 64: 507-510; doi:10.1093/jac/dkp210 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Ting-Shu Wu, Hsieh-Shong Leu, Cheng-Hsun Chiu, Ming-Hsun Lee, Ping-Cherng Chiang, Tsu-Lan Wu, Ju-Hsin Chia, Lin-Hui Su, An-Jing Kuo, and Hsin-Chih Lai

Clinical manifestations, antibiotic susceptibility and molecular analysis of Mycobacterium kansasii isolates from a university hospital in Taiwan
JAC Advance Access published on July 7, 2009
J. Antimicrob. Chemother. 2009 64: 511-514; doi:10.1093/jac/dkp238 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Jesús Oteo, Oscar Cuevas, Inmaculada López-Rodríguez, Ana Banderas-Florido, Ana Vindel, María Pérez-Vázquez, Verónica Bautista, Margarita Arroyo, Juan García-Caballero, Pilar Marín-Casanova, Rubén González-Sanz, Víctor Fuentes-Gómez, Salvador Oña-Compán, Silvia García-Cobos, and José Campos

Emergence of CTX-M-15-producing Klebsiella pneumoniae of multilocus sequence types 1, 11, 14, 17, 20, 35 and 36 as pathogens and colonizers in newborns and adults
JAC Advance Access published on June 13, 2009
J. Antimicrob. Chemother. 2009 64: 524-528; doi:10.1093/jac/dkp211 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Michael L. Beeton, Victoria J. Chalker, Sailesh Kotecha, and O. Brad Spiller

Comparison of full gyrA, gyrB, parC and parE gene sequences between all Ureaplasma parvum and Ureaplasma urealyticum serovars to separate true fluoroquinolone antibiotic resistance mutations from non-resistance polymorphism
JAC Advance Access published on June 30, 2009
J. Antimicrob. Chemother. 2009 64: 529-538; doi:10.1093/jac/dkp218 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Julia Walochnik, Andreas Obwaller, Florian Gruber, Michael Mildner, Erwin Tschachler, Miranda Suchomel, Michael Duchêne, and Herbert Auer

Anti-Acanthamoeba efficacy and toxicity of miltefosine in an organotypic skin equivalent
JAC Advance Access published on June 23, 2009
J. Antimicrob. Chemother. 2009 64: 539-545; doi:10.1093/jac/dkp215 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Clare Piper, Lorraine A. Draper, Paul D. Cotter, R. Paul Ross, and Colin Hill

A comparison of the activities of lacticin 3147 and nisin against drug-resistant Staphylococcus aureus and Enterococcus species
JAC Advance Access published on June 26, 2009
J. Antimicrob. Chemother. 2009 64: 546-551; doi:10.1093/jac/dkp221 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract M. McCracken, M. DeCorby, J. Fuller, V. Loo, D. J. Hoban, G. G. Zhanel, and M. R. Mulvey

Identification of multidrug- and carbapenem-resistant Acinetobacter baumannii in Canada: results from CANWARD 2007
JAC Advance Access published on July 3, 2009
J. Antimicrob. Chemother. 2009 64: 552-555; doi:10.1093/jac/dkp225 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Renu Singh, Kimberly R. Ledesma, Kai-Tai Chang, Jing-Guo Hou, Randall A. Prince, and Vincent H. Tam

Pharmacodynamics of moxifloxacin against a high inoculum of Escherichia coli in an in vitro infection model
JAC Advance Access published on July 9, 2009
J. Antimicrob. Chemother. 2009 64: 556-562; doi:10.1093/jac/dkp247 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Yun Cai, Yan Fan, Rui Wang, Mao-Mao An, and Bei-Bei Liang

Synergistic effects of aminoglycosides and fosfomycin on Pseudomonas aeruginosa in vitro and biofilm infections in a rat model
JAC Advance Access published on June 26, 2009
J. Antimicrob. Chemother. 2009 64: 563-566; doi:10.1093/jac/dkp224 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Anna L. Lazzell, Ashok K. Chaturvedi, Christopher G. Pierce, Deepthi Prasad, Priya Uppuluri, and Jose L. Lopez-Ribot

Treatment and prevention of Candida albicans biofilms with caspofungin in a novel central venous catheter murine model of candidiasis
JAC Advance Access published on July 7, 2009
J. Antimicrob. Chemother. 2009 64: 567-570; doi:10.1093/jac/dkp242 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Gloria M. González, Omar J. Portillo, Grecia I. Uscanga, Samantha E. Andrade, Miguel Robledo, Candelario Rodríguez, and Mariana Elizondo

Therapeutic efficacy of voriconazole against a fluconazole-resistant Candida albicans isolate in a vaginal model
JAC Advance Access published on June 30, 2009
J. Antimicrob. Chemother. 2009 64: 571-573; doi:10.1093/jac/dkp228 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Michael V. Schintler, Friederike Traunmüller, Julia Metzler, Gerhard Kreuzwirt, Stephan Spendel, Oliver Mauric, Martin Popovic, Erwin Scharnagl, and Christian Joukhadar

High fosfomycin concentrations in bone and peripheral soft tissue in diabetic patients presenting with bacterial foot infection
JAC Advance Access published on July 3, 2009
J. Antimicrob. Chemother. 2009 64: 574-578; doi:10.1093/jac/dkp230 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Sonia Molina-Pinelo, Alejandro Vallejo, Laura Díaz, Natalia Soriano-Sarabia, Sara Ferrando-Martínez, Salvador Resino, María Ángeles Muñoz-Fernández, and Manuel Leal

Premature immunosenescence in HIV-infected patients on highly active antiretroviral therapy with low-level CD4 T cell repopulation
JAC Advance Access published on July 16, 2009
J. Antimicrob. Chemother. 2009 64: 579-588; doi:10.1093/jac/dkp248 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Mar Masiá, Enrique Bernal, Sergio Padilla, Natalia García, José C. Escribano, Esteban Martínez, and Félix Gutiérrez

A pilot randomized trial comparing an intensive versus a standard intervention in stable HIV-infected patients with moderate–high cardiovascular risk
JAC Advance Access published on July 22, 2009
J. Antimicrob. Chemother. 2009 64: 589-598; doi:10.1093/jac/dkp250 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Camelia Protopopescu, François Raffi, Perrine Roux, Jacques Reynes, Pierre Dellamonica, Bruno Spire, Catherine Leport, Maria-Patrizia Carrieri, and on behalf of the ANRS CO8 (APROCO-COPILOTE) Study Group

Factors associated with non-adherence to long-term highly active antiretroviral therapy: a 10 year follow-up analysis with correction for the bias induced by missing data
JAC Advance Access published on July 14, 2009
J. Antimicrob. Chemother. 2009 64: 599-606; doi:10.1093/jac/dkp232 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract L. Bracciale, M. Colafigli, M. Zazzi, P. Corsi, P. Meraviglia, V. Micheli, R. Maserati, N. Gianotti, G. Penco, M. Setti, S. Di Giambenedetto, L. Butini, A. Vivarelli, M. Trezzi, and A. De Luca

Prevalence of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy: evolution over 12 years and predictors
JAC Advance Access published on July 16, 2009
J. Antimicrob. Chemother. 2009 64: 607-615; doi:10.1093/jac/dkp246 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Maurizio Zazzi, Mattia Prosperi, Ilaria Vicenti, Simona Di Giambenedetto, Annapaola Callegaro, Bianca Bruzzone, Fausto Baldanti, Angela Gonnelli, Enzo Boeri, Elisabetta Paolini, Stefano Rusconi, Andrea Giacometti, Franco Maggiolo, Stefano Menzo, and Andrea De Luca on behalf of the ARCA Collaborative Group

Rules-based HIV-1 genotypic resistance interpretation systems predict 8 week and 24 week virological antiretroviral treatment outcome and benefit from drug potency weighting
JAC Advance Access published on July 19, 2009
J. Antimicrob. Chemother. 2009 64: 616-624; doi:10.1093/jac/dkp252 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Matteo Bassetti, Filippo Ansaldi, Laura Nicolini, Emanuele Malfatto, Maria Pia Molinari, Michele Mussap, Barbara Rebesco, Franco Bobbio Pallavicini, Giancarlo Icardi, and Claudio Viscoli

Incidence of candidaemia and relationship with fluconazole use in an intensive care unit
JAC Advance Access published on July 21, 2009
J. Antimicrob. Chemother. 2009 64: 625-629; doi:10.1093/jac/dkp251 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Jan Hitchcock, Annette P. Jepson, Janice Main, and Hayley J. Wickens

Establishment of an outpatient and home parenteral antimicrobial therapy service at a London teaching hospital: a case series
JAC Advance Access published on June 23, 2009
J. Antimicrob. Chemother. 2009 64: 630-634; doi:10.1093/jac/dkp212 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Paul J. Rooney, Maureen C. O'Leary, Anne C. Loughrey, Mark McCalmont, Brian Smyth, Philip Donaghy, Motasim Badri, Neil Woodford, Edi Karisik, and David M. Livermore

Nursing homes as a reservoir of extended-spectrum β-lactamase (ESBL)-producing ciprofloxacin-resistant Escherichia coli
JAC Advance Access published on June 23, 2009
J. Antimicrob. Chemother. 2009 64: 635-641; doi:10.1093/jac/dkp220 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Anders Hviid and Henrik Svanström

Antibiotic use and intussusception in early childhood
JAC Advance Access published on June 23, 2009
J. Antimicrob. Chemother. 2009 64: 642-648; doi:10.1093/jac/dkp217 [Abstract] [Full Text] [PDF] [Request Permissions]  

Research letters

Susan O'Shea, Lesley Cotter, Sinead Creagh, Sara Lydon, and Brigid Lucey

Mupirocin resistance among staphylococci: trends in the southern region of Ireland
JAC Advance Access published on June 30, 2009
J. Antimicrob. Chemother. 2009 64: 649-650; doi:10.1093/jac/dkp227 [Extract] [Full Text] [PDF] [Request Permissions]  

Alfred Dieudonné Kinana, Vito Ricci, and Laura J. V. Piddock

Contribution of efflux to antibiotic resistance in Campylobacter isolated from poultry in Senegal
JAC Advance Access published on July 3, 2009
J. Antimicrob. Chemother. 2009 64: 650-652; doi:10.1093/jac/dkp235 [Extract] [Full Text] [PDF] [Request Permissions]  

Anaïs Potron, Laurent Poirel, Sandrine Bernabeu, Xavier Monnet, Christian Richard, and Patrice Nordmann

Nosocomial spread of ESBL-positive Enterobacter cloacae co-expressing plasmid-mediated quinolone resistance Qnr determinants in one hospital in France
JAC Advance Access published on June 23, 2009
J. Antimicrob. Chemother. 2009 64: 653-654; doi:10.1093/jac/dkp222 [Extract] [Full Text] [PDF] [Request Permissions]  

Vito Ricci and Laura J. V. Piddock

Only for substrate antibiotics are a functional AcrAB–TolC efflux pump and RamA required to select multidrug-resistant Salmonella Typhimurium
JAC Advance Access published on June 30, 2009
J. Antimicrob. Chemother. 2009 64: 654-657; doi:10.1093/jac/dkp234 [Extract] [Full Text] [PDF] [Request Permissions]  

Csilla Ratkai, Sandra Quinteira, Filipa Grosso, Nuno Monteiro, Elisabeth Nagy, and Luísa Peixe

Controlling for false positives: interpreting MBL Etest and MBL combined disc test for the detection of metallo-β-lactamases
JAC Advance Access published on June 30, 2009
J. Antimicrob. Chemother. 2009 64: 657-658; doi:10.1093/jac/dkp229 [Extract] [Full Text] [PDF] [Request Permissions]  

Samir N. Patel, Dylan R. Pillai, Sylvia Pong-Porter, Allison McGeer, Karen Green, and Donald E. Low

In vitro activity of ceftaroline, ceftobiprole and cethromycin against clinical isolates of Streptococcus pneumoniae collected from across Canada between 2003 and 2008
JAC Advance Access published on July 3, 2009
J. Antimicrob. Chemother. 2009 64: 659-660; doi:10.1093/jac/dkp231 [Extract] [Full Text] [PDF] [Request Permissions]  

Ulrike Nienhoff, Kristina Kadlec, Iris F. Chaberny, Jutta Verspohl, Gerald-F. Gerlach, Stefan Schwarz, Daniela Simon, and Ingo Nolte

Transmission of methicillin-resistant Staphylococcus aureus strains between humans and dogs: two case reports
JAC Advance Access published on July 16, 2009
J. Antimicrob. Chemother. 2009 64: 660-662; doi:10.1093/jac/dkp243 [Extract] [Full Text] [PDF] [Request Permissions]  

Hadrien Rozé, Mathieu Lafargue, Olivier Joannes-Boyau, Hélène Batoz, Claire Dromer, Dominique Breilh, and Gérard Janvier

Toxicokinetics of voriconazole during massive intentional poisoning
JAC Advance Access published on June 17, 2009
J. Antimicrob. Chemother. 2009 64: 662-663; doi:10.1093/jac/dkp219 [Extract] [Full Text] [PDF] [Request Permissions]  

Philippa Horsfield, Sanjay Deshpande, and Richard Ellis

Killing with kindness? Drug reaction eosinophilia with systemic symptoms (DRESS) masquerading as acute severe sepsis
JAC Advance Access published on June 30, 2009
J. Antimicrob. Chemother. 2009 64: 663-665; doi:10.1093/jac/dkp236 [Extract] [Full Text] [PDF] [Request Permissions]  

Frédéric Lamoth, Thierry Buclin, Andres Pascual, Thierry Calandra, and Oscar Marchetti

Imipenem underdosing as a cause of persistent neutropenic fever?
JAC Advance Access published on July 7, 2009
J. Antimicrob. Chemother. 2009 64: 665-667; doi:10.1093/jac/dkp233 [Extract] [Full Text] [PDF] [Request Permissions]  

Fred S. Sarfo, David F. Bibby, Uli Schwab, Lambert T. Appiah, Duncan A. Clark, Paul Collini, Richard Phillips, Ingrid Green, Matthias T. Dittmar, and David R. Chadwick

Inadvertent non-nucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral therapy in dual HIV-1/2 and HIV-2 seropositive West Africans: a retrospective study
JAC Advance Access published on June 23, 2009
J. Antimicrob. Chemother. 2009 64: 667-669; doi:10.1093/jac/dkp216 [Extract] [Full Text] [PDF] [Request Permissions]  

Book review

Leonard Leibovici

The Patient as Victim and Vector: Ethics and Infectious Disease
JAC Advance Access published on June 19, 2009
J. Antimicrob. Chemother. 2009 64: 670; doi:10.1093/jac/dkp223 [Extract] [Full Text] [PDF] [Request Permissions]  

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