Journal of Antimicrobial Chemotherapy

Reviews

Get checked abstract F. Kate Gould, Richard Brindle, Paul R. Chadwick, Adam P. Fraise, Simon Hill, Dilip Nathwani, Geoff L. Ridgway, Michael J. Spry, and Rod E. Warren on behalf of the MRSA Working Party of the British Society for Antimicrobial Chemotherapy

Guidelines (2008) for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in the United Kingdom
JAC Advance Access published on March 12, 2009
J. Antimicrob. Chemother. 2009 63: 849-861; doi:10.1093/jac/dkp065 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Lauren Nassetta, David Kimberlin, and Richard Whitley

Treatment of congenital cytomegalovirus infection: implications for future therapeutic strategies
JAC Advance Access published on March 14, 2009
J. Antimicrob. Chemother. 2009 63: 862-867; doi:10.1093/jac/dkp083 [Abstract] [Full Text] [PDF] [Request Permissions]  

Original research

Get checked abstract O. Nilsson, C. Greko, J. Top, A. Franklin, and B. Bengtsson

Spread without known selective pressure of a vancomycin-resistant clone of Enterococcus faecium among broilers
JAC Advance Access published on February 24, 2009
J. Antimicrob. Chemother. 2009 63: 868-872; doi:10.1093/jac/dkp045 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract F. El Garch, M. Hallin, R. De Mendonça, O. Denis, A. Lefort, and M. J. Struelens

StaphVar-DNA microarray analysis of accessory genome elements of community-acquired methicillin-resistant Staphylococcus aureus
JAC Advance Access published on March 19, 2009
J. Antimicrob. Chemother. 2009 63: 877-885; doi:10.1093/jac/dkp089 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Surbhi Malhotra-Kumar, Liesbet Van Heirstraeten, Christine Lammens, Sabine Chapelle, and Herman Goossens

Emergence of high-level fluoroquinolone resistance in emm6 Streptococcus pyogenes and in vitro resistance selection with ciprofloxacin, levofloxacin and moxifloxacin
JAC Advance Access published on March 11, 2009
J. Antimicrob. Chemother. 2009 63: 886-894; doi:10.1093/jac/dkp057 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Wen'en Liu, Lamei Chen, Hongling Li, Huili Duan, Yunli Zhang, Xianghui Liang, Xian Li, Mingxiang Zou, Li Xu, and Peter M. Hawkey

Novel CTX-M β-lactamase genotype distribution and spread into multiple species of Enterobacteriaceae in Changsha, Southern China
JAC Advance Access published on March 18, 2009
J. Antimicrob. Chemother. 2009 63: 895-900; doi:10.1093/jac/dkp068 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Cristina Pellegrini, Paola Sandra Mercuri, Giuseppe Celenza, Moreno Galleni, Bernardetta Segatore, Elisa Sacchetti, Roberto Volpe, Gianfranco Amicosante, and Mariagrazia Perilli

Identification of bla_IMP-22 in Pseudomonas spp. in urban wastewater and nosocomial environments: biochemical characterization of a new IMP metallo-enzyme variant and its genetic location
JAC Advance Access published on March 6, 2009
J. Antimicrob. Chemother. 2009 63: 901-908; doi:10.1093/jac/dkp061 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Vito Ricci and Laura J. V. Piddock

Ciprofloxacin selects for multidrug resistance in Salmonella enterica serovar Typhimurium mediated by at least two different pathways
JAC Advance Access published on March 6, 2009
J. Antimicrob. Chemother. 2009 63: 909-916; doi:10.1093/jac/dkp054 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Xiao-Ying Pu, Jing-Cao Pan, Hao-Qiu Wang, Wei Zhang, Zhi-Cheng Huang, and Yang-Ming Gu

Characterization of fluoroquinolone-resistant Shigella flexneri in Hangzhou area of China
JAC Advance Access published on March 18, 2009
J. Antimicrob. Chemother. 2009 63: 917-920; doi:10.1093/jac/dkp087 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Jacques Bolard, John D. Cleary, and Robert E. Kramer

Evidence that impurities contribute to the fluorescence of the polyene antibiotic amphotericin B
JAC Advance Access published on March 3, 2009
J. Antimicrob. Chemother. 2009 63: 921-927; doi:10.1093/jac/dkp059 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Nicola J. Beresford, Debbie Mulhearn, Bruce Szczepankiewicz, Gang Liu, Michael E. Johnson, Anthony Fordham-Skelton, Cele Abad-Zapatero, Jennifer S. Cavet, and Lydia Tabernero

Inhibition of MptpB phosphatase from Mycobacterium tuberculosis impairs mycobacterial survival in macrophages
JAC Advance Access published on February 24, 2009
J. Antimicrob. Chemother. 2009 63: 928-936; doi:10.1093/jac/dkp031 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Karin Sauer, Janusz Steczko, and Stephen R. Ash

Effect of a solution containing citrate/Methylene Blue/parabens on Staphylococcus aureus bacteria and biofilm, and comparison with various heparin solutions
JAC Advance Access published on March 12, 2009
J. Antimicrob. Chemother. 2009 63: 937-945; doi:10.1093/jac/dkp060 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Byeonghwa Jeon and Qijing Zhang

Sensitization of Campylobacter jejuni to fluoroquinolone and macrolide antibiotics by antisense inhibition of the CmeABC multidrug efflux transporter
JAC Advance Access published on March 11, 2009
J. Antimicrob. Chemother. 2009 63: 946-948; doi:10.1093/jac/dkp067 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Chang Ji Zheng, Mi-Jin Sohn, and Won-Gon Kim

Vinaxanthone, a new FabI inhibitor from Penicillium sp.
JAC Advance Access published on March 12, 2009
J. Antimicrob. Chemother. 2009 63: 949-953; doi:10.1093/jac/dkp058 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Ian A. Critchley, Louis S. Green, Casey L. Young, James M. Bullard, Ron J. Evans, Melissa Price, Thale C. Jarvis, Joseph W. Guiles, Nebojsa Janjic, and Urs A. Ochsner

Spectrum of activity and mode of action of REP3123, a new antibiotic to treat Clostridium difficile infections
JAC Advance Access published on March 3, 2009
J. Antimicrob. Chemother. 2009 63: 954-963; doi:10.1093/jac/dkp041 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Urs A. Ochsner, Stacie J. Bell, Ann L. O'Leary, Teresa Hoang, Kimberley Clawson Stone, Casey L. Young, Ian A. Critchley, and Nebojsa Janjic

Inhibitory effect of REP3123 on toxin and spore formation in Clostridium difficile, and in vivo efficacy in a hamster gastrointestinal infection model
JAC Advance Access published on February 26, 2009
J. Antimicrob. Chemother. 2009 63: 964-971; doi:10.1093/jac/dkp042 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Diane M. Citron, Yumi A. Warren, Kerin L. Tyrrell, Vreni Merriam, and Ellie J. C. Goldstein

Comparative in vitro activity of REP3123 against Clostridium difficile and other anaerobic intestinal bacteria
JAC Advance Access published on February 24, 2009
J. Antimicrob. Chemother. 2009 63: 972-976; doi:10.1093/jac/dkp037 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Damir Begic, Christof von Eiff, and Brian T. Tsuji

Daptomycin pharmacodynamics against Staphylococcus aureus hemB mutants displaying the small colony variant phenotype
JAC Advance Access published on March 19, 2009
J. Antimicrob. Chemother. 2009 63: 977-981; doi:10.1093/jac/dkp069 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Pornpan Koomanachai, Aryun Kim, and David P. Nicolau

Pharmacodynamic evaluation of tigecycline against Acinetobacter baumannii in a murine pneumonia model
JAC Advance Access published on March 11, 2009
J. Antimicrob. Chemother. 2009 63: 982-987; doi:10.1093/jac/dkp056 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Martin Vogel, Norbert Bertram, Jan-Christian Wasmuth, Christoph Wyen, Esther Voigt, Carolynne Schwarze-Zander, Thomas Sudhop, Gerd Fätkenheuer, Jürgen K. Rockstroh, and Christoph Reichel

Nevirapine pharmacokinetics in HIV-infected and HIV/HCV-coinfected individuals
JAC Advance Access published on March 6, 2009
J. Antimicrob. Chemother. 2009 63: 988-991; doi:10.1093/jac/dkp044 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract José Moltó, Josep Maria Llibre, Esteban Ribera, Carlos Mínguez, Jesús Sánchez del Río, Enric Pedrol, Gabriel Vallecillo, Samandhy Cedeño, Marta Valle, Cristina Miranda, Eugenia Negredo, and Bonaventura Clotet on behalf of the SQV-HEP Study Group

Saquinavir exposure in HIV-infected patients with chronic viral hepatitis
JAC Advance Access published on March 11, 2009
J. Antimicrob. Chemother. 2009 63: 992-997; doi:10.1093/jac/dkp070 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract P. Tebas, J. Zhang, R. Hafner, K. Tashima, A. Shevitz, K. Yarasheski, B. Berzins, S. Owens, J. Forand, S. Evans, and R. Murphy

Peripheral and visceral fat changes following a treatment switch to a non-thymidine analogue or a nucleoside-sparing regimen in HIV-infected subjects with peripheral lipoatrophy: results of ACTG A5110
JAC Advance Access published on March 19, 2009
J. Antimicrob. Chemother. 2009 63: 998-1005; doi:10.1093/jac/dkp071 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Eva Poveda, Eduardo Seclén, María del Mar González, Federico García, Natalia Chueca, Antonio Aguilera, Jose Javier Rodríguez, Juan González-Lahoz, and Vincent Soriano

Design and validation of new genotypic tools for easy and reliable estimation of HIV tropism before using CCR5 antagonists
JAC Advance Access published on March 3, 2009
J. Antimicrob. Chemother. 2009 63: 1006-1010; doi:10.1093/jac/dkp063 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Erwin L. van der Veen, Anne G. M. Schilder, Tim K. Timmers, Maroeska M. Rovers, Ad C. Fluit, Marc J. Bonten, and Maurine A. Leverstein-van Hall

Effect of long-term trimethoprim/sulfamethoxazole treatment on resistance and integron prevalence in the intestinal flora: a randomized, double-blind, placebo-controlled trial in children
JAC Advance Access published on March 18, 2009
J. Antimicrob. Chemother. 2009 63: 1011-1016; doi:10.1093/jac/dkp050 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Chao-Hung Kuo, Huang-Ming Hu, Fu-Chen Kuo, Ping-I. Hsu, Angela Chen, Fang-Jung Yu, Pei-Yun Tsai, I.-Chen Wu, Sheng-Wen Wang, Chia-Jung Li, Bi-Chuang Weng, Lin-Li Chang, Chang-Ming Jan, Wen-Ming Wang, and Deng-Chyang Wu

Efficacy of levofloxacin-based rescue therapy for Helicobacter pylori infection after standard triple therapy: a randomized controlled trial
JAC Advance Access published on February 26, 2009
J. Antimicrob. Chemother. 2009 63: 1017-1024; doi:10.1093/jac/dkp034 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract A. Tessmer, T. Welte, P. Martus, M. Schnoor, R. Marre, and N. Suttorp

Impact of intravenous β-lactam/macrolide versus β-lactam monotherapy on mortality in hospitalized patients with community-acquired pneumonia
JAC Advance Access published on March 17, 2009
J. Antimicrob. Chemother. 2009 63: 1025-1033; doi:10.1093/jac/dkp088 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Evan J. Begg, Jane W. A. Vella-Brincat, Barbara Robertshawe, Mark J. McMurtrie, Carl M. J. Kirkpatrick, and Brian Darlow

Eight years' experience of an extended-interval dosing protocol for gentamicin in neonates
JAC Advance Access published on March 19, 2009
J. Antimicrob. Chemother. 2009 63: 1043-1049; doi:10.1093/jac/dkp073 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract A. H. Thomson, C. E. Staatz, C. M. Tobin, M. Gall, and A. M. Lovering

Development and evaluation of vancomycin dosage guidelines designed to achieve new target concentrations
JAC Advance Access published on March 19, 2009
J. Antimicrob. Chemother. 2009 63: 1050-1057; doi:10.1093/jac/dkp085 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Philippe Lesprit, Trung Duong, Emmanuelle Girou, François Hemery, and Christian Brun-Buisson

Impact of a computer-generated alert system prompting review of antibiotic use in hospitals
JAC Advance Access published on March 5, 2009
J. Antimicrob. Chemother. 2009 63: 1058-1063; doi:10.1093/jac/dkp062 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Heidi S. M. Ammerlaan, Annet Troelstra, Cas L. J. J. Kruitwagen, Jan A. J. W. Kluytmans, and Marc J. M. Bonten

Quantifying changes in incidences of nosocomial bacteraemia caused by antibiotic-susceptible and antibiotic-resistant pathogens
JAC Advance Access published on February 26, 2009
J. Antimicrob. Chemother. 2009 63: 1064-1070; doi:10.1093/jac/dkp036 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Research letters

Pauline D. Mugnier, Khalid Mubarak Bindayna, Laurent Poirel, and Patrice Nordmann

Diversity of plasmid-mediated carbapenem-hydrolysing oxacillinases among carbapenem-resistant Acinetobacter baumannii isolates from Kingdom of Bahrain
JAC Advance Access published on February 27, 2009
J. Antimicrob. Chemother. 2009 63: 1071-1073; doi:10.1093/jac/dkp052 [Extract] [Full Text] [PDF] [Request Permissions]  

Pierre Bogaerts, Hector Rodriguez-Villalobos, Christine Laurent, Ariane Deplano, Marc J. Struelens, and Youri Glupczynski

Emergence of extended-spectrum-AmpC-expressing Escherichia coli isolates in Belgian hospitals
JAC Advance Access published on February 24, 2009
J. Antimicrob. Chemother. 2009 63: 1073-1075; doi:10.1093/jac/dkp046 [Extract] [Full Text] [PDF] [Request Permissions]  

D. W. Wareham, N. C. Gordon, J. B. Casals, and D. C. Bean

Reduced susceptibility of multidrug-resistant Acinetobacter baumannii to tigecycline in combination with 1-(1-naphthylmethyl)-piperazine is not a pH-dependent phenomenon
JAC Advance Access published on March 11, 2009
J. Antimicrob. Chemother. 2009 63: 1075-1076; doi:10.1093/jac/dkp072 [Extract] [Full Text] [PDF] [Request Permissions]  

A. Hames, J. D. Perry, and F. K. Gould

In vitro effect of metronidazole and vancomycin in combination on Clostridium difficile
JAC Advance Access published on February 24, 2009
J. Antimicrob. Chemother. 2009 63: 1076; doi:10.1093/jac/dkp048 [Extract] [Full Text] [PDF] [Request Permissions]  

Georg Mayerhofer, Irina Schwaiger-Nemirova, Thomas Kuhn, Leopold Girsch, and Franz Allerberger

Detecting streptomycin in apples from orchards treated for fire blight
JAC Advance Access published on February 24, 2009
J. Antimicrob. Chemother. 2009 63: 1076-1077; doi:10.1093/jac/dkp055 [Extract] [Full Text] [PDF] [Request Permissions]  

Letters to the Editor

David Lechuga-Ballesteros, Vu Truong-Le, and Eric J. Patzer

Comment on: Resistance of planktonic and biofilm-grown Burkholderia cepacia complex isolates to the transition metal gallium
JAC Advance Access published on March 19, 2009
J. Antimicrob. Chemother. 2009 63: 1078-1079; doi:10.1093/jac/dkp086 [Extract] [Full Text] [PDF] [Request Permissions]  

Elke Peeters, Hans J. Nelis, and Tom Coenye

Resistance of planktonic and biofilm-grown Burkholderia cepacia complex isolates to the transition metal gallium—authors’ response
JAC Advance Access published on March 24, 2009
J. Antimicrob. Chemother. 2009 63: 1079; doi:10.1093/jac/dkp110 [Extract] [Full Text] [PDF] [Request Permissions]  

Jean-Jacques Parienti

Comment on: High rate of early virological failure with the once-daily tenofovir/lamivudine/nevirapine combination in naive HIV-1-infected patients
JAC Advance Access published on January 21, 2009
J. Antimicrob. Chemother. 2009 63: 1080; doi:10.1093/jac/dkn556 [Extract] [Full Text] [PDF] [Request Permissions]  

D. Rey, B. Hoen, P. Chavanet, M. P. Schmitt, G. Hoizey, P. Meyer, G. Peytavin, B. Spire, C. Allavena, M. Diemer, T. May, J. L. Schmit, M. Duong, V. Calvez, and J. M. Lang

High rate of early virological failure with the once-daily tenofovir/lamivudine/nevirapine combination in naive HIV-1-infected patients—authors' response
JAC Advance Access published on March 12, 2009
J. Antimicrob. Chemother. 2009 63: 1080-1081; doi:10.1093/jac/dkp064 [Extract] [Full Text] [PDF] [Request Permissions]  

Emma Edmond Keuleyan and Krastju Georgiev Kirilov

Comment on: Aminoglycoside drugs in clinical practice: an evidence-based approach
JAC Advance Access published on February 27, 2009
J. Antimicrob. Chemother. 2009 63: 1081-1082; doi:10.1093/jac/dkp053 [Extract] [Full Text] [PDF] [Request Permissions]  

Leonard Leibovici, Liat Vidal, and Mical Paul

Aminoglycoside drugs in clinical practice: an evidence-based approach—authors' response
JAC Advance Access published on March 14, 2009
J. Antimicrob. Chemother. 2009 63: 1082-1083; doi:10.1093/jac/dkp091 [Extract] [Full Text] [PDF] [Request Permissions]  

Jochen W. L. Cals

Comment on: The higher the number of daily doses of antibiotic treatment in lower respiratory tract infection the worse the compliance
JAC Advance Access published on February 24, 2009
J. Antimicrob. Chemother. 2009 63: 1083-1084; doi:10.1093/jac/dkp049 [Extract] [Full Text] [PDF] [Request Permissions]  

Carl Llor

The higher the number of daily doses of antibiotic treatment in lower respiratory tract infection the worse the compliance—author's response
JAC Advance Access published on March 14, 2009
J. Antimicrob. Chemother. 2009 63: 1084-1085; doi:10.1093/jac/dkp093 [Extract] [Full Text] [PDF] [Request Permissions]  

Book review

D. M. Livermore

Antimicrobial Drugs: Chronicle of a Twentieth Century Medical Triumph
JAC Advance Access published on March 8, 2009
J. Antimicrob. Chemother. 2009 63: 1086; doi:10.1093/jac/dkp066 [Extract] [Full Text] [PDF] [Request Permissions]  

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