Journal of Antimicrobial Chemotherapy

Original research

Get checked abstract Jiahui Liu, Paula Keelan, Peter M. Bennett, and Virve I. Enne

Characterization of a novel macrolide efflux gene, mef(B), found linked to sul3 in porcine Escherichia coli
JAC Advance Access published on January 8, 2009
J. Antimicrob. Chemother. 2009 63: 423-426; doi:10.1093/jac/dkn523 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Andrea Endimiani, Andrea M. Hujer, Federico Perez, Christopher R. Bethel, Kristine M. Hujer, Jennifer Kroeger, Margret Oethinger, David L. Paterson, Mark D. Adams, Michael R. Jacobs, Daniel J. Diekema, Gerri S. Hall, Stephen G. Jenkins, Louis B. Rice, Fred C. Tenover, and Robert A. Bonomo

Characterization of bla_KPC-containing Klebsiella pneumoniae isolates detected in different institutions in the Eastern USA
JAC Advance Access published on January 20, 2009
J. Antimicrob. Chemother. 2009 63: 427-437; doi:10.1093/jac/dkn547 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract N. Pugliese, F. Maimone, M. Scrascia, S. F. Materu, and Carlo Pazzani

SXT-related integrating conjugative element and IncC plasmids in Vibrio cholerae O1 strains in Eastern Africa
JAC Advance Access published on January 20, 2009
J. Antimicrob. Chemother. 2009 63: 438-442; doi:10.1093/jac/dkn542 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Emmanuelle Cambau, Stephanie Matrat, Xiao-Su Pan, Romain Roth Dit Bettoni, Céline Corbel, Alexandra Aubry, Christine Lascols, Jean-Yves Driot, and L. Mark Fisher

Target specificity of the new fluoroquinolone besifloxacin in Streptococcus pneumoniae, Staphylococcus aureus and Escherichia coli
JAC Advance Access published on January 15, 2009
J. Antimicrob. Chemother. 2009 63: 443-450; doi:10.1093/jac/dkn528 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Richard A. Slayden and John T. Belisle

Morphological features and signature gene response elicited by inactivation of FtsI in Mycobacterium tuberculosis
JAC Advance Access published on December 24, 2008
J. Antimicrob. Chemother. 2009 63: 451-457; doi:10.1093/jac/dkn507 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Marie-Line Reynaert, Anne-Cécile Hochart-Behra, Josette Behra-Miellet, Bernard Gressier, Louis Mine, Thierry Dine, Michel Luyckx, Luc Dubreuil, and Claude Brunet

Comparison of the in vitro effects of amoxicillin and ampicillin on the polymorphonuclear neutrophil respiratory burst
JAC Advance Access published on January 18, 2009
J. Antimicrob. Chemother. 2009 63: 458-461; doi:10.1093/jac/dkn545 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Byeonghwa Jeon, Wayne Muraoka, Alexandra Scupham, and Qijing Zhang

Roles of lipooligosaccharide and capsular polysaccharide in antimicrobial resistance and natural transformation of Campylobacter jejuni
JAC Advance Access published on January 15, 2009
J. Antimicrob. Chemother. 2009 63: 462-468; doi:10.1093/jac/dkn529 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Eduardo Caio Torres-Santos, Maria Isabel Sampaio-Santos, Frederick S. Buckner, Kohei Yokoyama, Michael Gelb, Julio A. Urbina, and Bartira Rossi-Bergmann

Altered sterol profile induced in Leishmania amazonensis by a natural dihydroxymethoxylated chalcone
JAC Advance Access published on January 28, 2009
J. Antimicrob. Chemother. 2009 63: 469-472; doi:10.1093/jac/dkn546 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Christopher G. Pierce, Derek P. Thomas, and José L. López-Ribot

Effect of tunicamycin on Candida albicans biofilm formation and maintenance
JAC Advance Access published on December 20, 2008
J. Antimicrob. Chemother. 2009 63: 473-479; doi:10.1093/jac/dkn515 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Ashraf A. Kadry, Soliman I. Fouda, Atef M. Shibl, and Ahmed A. Abu El-Asrar

Impact of slime dispersants and anti-adhesives on in vitro biofilm formation of Staphylococcus epidermidis on intraocular lenses and on antibiotic activities
JAC Advance Access published on January 14, 2009
J. Antimicrob. Chemother. 2009 63: 480-484; doi:10.1093/jac/dkn533 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Warren E. Rose and Peter T. Poppens

Impact of biofilm on the in vitro activity of vancomycin alone and in combination with tigecycline and rifampicin against Staphylococcus aureus
JAC Advance Access published on December 24, 2008
J. Antimicrob. Chemother. 2009 63: 485-488; doi:10.1093/jac/dkn513 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Steven N. Leonard, Kerri L. Rossi, Karly L. Newton, and Michael J. Rybak

Evaluation of the Etest GRD for the detection of Staphylococcus aureus with reduced susceptibility to glycopeptides
JAC Advance Access published on January 9, 2009
J. Antimicrob. Chemother. 2009 63: 489-492; doi:10.1093/jac/dkn520 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Michael A. John, Julia Burden, J. Ian Stuart, Romina C. Reyes, Robert Lannigan, Sue Milburn, Deb Diagre, Bev Wilson, and Zafar Hussain

Comparison of three phenotypic techniques for detection of methicillin resistance in Staphylococcus spp. reveals a species-dependent performance
JAC Advance Access published on January 10, 2009
J. Antimicrob. Chemother. 2009 63: 493-496; doi:10.1093/jac/dkn527 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Helen Derbyshire, Gemma Kay, Katie Evans, Carmel Vaughan, Umadevi Kavuri, and Trevor Winstanley

A simple disc diffusion method for detecting AmpC and extended-spectrum β-lactamases in clinical isolates of Enterobacteriaceae
JAC Advance Access published on January 20, 2009
J. Antimicrob. Chemother. 2009 63: 497-501; doi:10.1093/jac/dkn535 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Helen Rose, Adam Baldwin, Christopher G. Dowson, and Eshwar Mahenthiralingam

Biocide susceptibility of the Burkholderia cepacia complex
JAC Advance Access published on January 18, 2009
J. Antimicrob. Chemother. 2009 63: 502-510; doi:10.1093/jac/dkn540 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Christopher J. Harrison, Charles Woods, Gordon Stout, Brittanie Martin, and Rangaraj Selvarangan

Susceptibilities of Haemophilus influenzae, Streptococcus pneumoniae, including serotype 19A, and Moraxella catarrhalis paediatric isolates from 2005 to 2007 to commonly used antibiotics
JAC Advance Access published on January 27, 2009
J. Antimicrob. Chemother. 2009 63: 511-519; doi:10.1093/jac/dkn538 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Simon D. Baines, Rachel O'Connor, Katie Saxton, Jane Freeman, and Mark H. Wilcox

Activity of vancomycin against epidemic Clostridium difficile strains in a human gut model
JAC Advance Access published on December 26, 2008
J. Antimicrob. Chemother. 2009 63: 520-525; doi:10.1093/jac/dkn502 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract André C. Amaral, Anamélia L. Bocca, Alice M. Ribeiro, Janayna Nunes, Danielle L. G. Peixoto, Andreza R. Simioni, Fernando L. Primo, Zulmira G. M. Lacava, Ricardo Bentes, Ricardo Titze-de-Almeida, Antonio C. Tedesco, Paulo C. Morais, and Maria Sueli S. Felipe

Amphotericin B in poly(lactic-co-glycolic acid) (PLGA) and dimercaptosuccinic acid (DMSA) nanoparticles against paracoccidioidomycosis
JAC Advance Access published on January 16, 2009
J. Antimicrob. Chemother. 2009 63: 526-533; doi:10.1093/jac/dkn539 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Nobumasa Aoki, Kazuhiro Tateda, Yoshiaki Kikuchi, Soichiro Kimura, Choichiroh Miyazaki, Yoshikazu Ishii, Yoshinari Tanabe, Fumitake Gejyo, and Keizo Yamaguchi

Efficacy of colistin combination therapy in a mouse model of pneumonia caused by multidrug-resistant Pseudomonas aeruginosa
JAC Advance Access published on January 14, 2009
J. Antimicrob. Chemother. 2009 63: 534-542; doi:10.1093/jac/dkn530 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Jennifer Keiser, Marie-Stella Gruyer, Nancy Perrottet, Boris Zanolari, Thomas Mercier, and Laurent Decosterd

Pharmacokinetic parameters of artesunate and dihydroartemisinin in rats infected with Fasciola hepatica
JAC Advance Access published on January 24, 2009
J. Antimicrob. Chemother. 2009 63: 543-549; doi:10.1093/jac/dkn550 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Juan P. Horcajada, Rebeka Atienza, María Sarasa, Dolors Soy, Alfredo Adán, and Josep Mensa

Pharmacokinetics of linezolid in human non-inflamed vitreous after systemic administration
JAC Advance Access published on December 24, 2008
J. Antimicrob. Chemother. 2009 63: 550-552; doi:10.1093/jac/dkn516 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract A. M. Lovering, R. Le Floch, L. Hovsepian, J. Stephanazzi, P. Bret, G. Birraux, and C. Vinsonneau

Pharmacokinetic evaluation of linezolid in patients with major thermal injuries
JAC Advance Access published on January 18, 2009
J. Antimicrob. Chemother. 2009 63: 553-559; doi:10.1093/jac/dkn541 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Sutep Jaruratanasirikul and Teeratad Sudsai

Comparison of the pharmacodynamics of imipenem in patients with ventilator-associated pneumonia following administration by 2 or 0.5 h infusion
JAC Advance Access published on January 18, 2009
J. Antimicrob. Chemother. 2009 63: 560-563; doi:10.1093/jac/dkn543 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Philippe Seguin, Marie Clémence Verdier, Charles Chanavaz, Charlotte Engrand, Bruno Laviolle, Pierre-Yves Donnio, and Yannick Mallédant

Plasma and peritoneal concentration following continuous infusion of cefotaxime in patients with secondary peritonitis
JAC Advance Access published on January 23, 2009
J. Antimicrob. Chemother. 2009 63: 564-567; doi:10.1093/jac/dkn522 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract M. Ortega, F. Marco, A. Soriano, M. Almela, J. A. Martínez, A. Muñoz, and J. Mensa

Analysis of 4758 Escherichia coli bacteraemia episodes: predictive factors for isolation of an antibiotic-resistant strain and their impact on the outcome
JAC Advance Access published on January 6, 2009
J. Antimicrob. Chemother. 2009 63: 568-574; doi:10.1093/jac/dkn514 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Francesca Gatti, Paola Nasta, Arianna Loregian, Massimo Puoti, Alessandro Matti, Silvana Pagni, Daniel Gonzalez de Requena, Katiela Prestini, Saverio G. Parisi, Stefano Bonora, Giorgio Palù, and Giampiero Carosi

Unboosted fosamprenavir is associated with low drug exposure in HIV-infected patients with mild–moderate liver impairment resulting from HCV-related cirrhosis
JAC Advance Access published on January 16, 2009
J. Antimicrob. Chemother. 2009 63: 575-578; doi:10.1093/jac/dkn525 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Jean-Luc Meynard, Karine Lacombe, Jean-Marie Poirier, Jennifer Legrand, Laurence Morand-Joubert, and Pierre-Marie Girard

Influence of liver fibrosis stage on plasma levels of efavirenz in HIV-infected patients with chronic hepatitis B or C
JAC Advance Access published on January 23, 2009
J. Antimicrob. Chemother. 2009 63: 579-584; doi:10.1093/jac/dkn531 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Diane Descamps, Sidonie Lambert-Niclot, Anne-Geneviève Marcelin, Gilles Peytavin, Bénédicte Roquebert, Christine Katlama, Patrick Yeni, Mathieu Felices, Vincent Calvez, and Françoise Brun-Vézinet

Mutations associated with virological response to darunavir/ritonavir in HIV-1-infected protease inhibitor-experienced patients
JAC Advance Access published on January 15, 2009
J. Antimicrob. Chemother. 2009 63: 585-592; doi:10.1093/jac/dkn544 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract André F. Santos, Ana B. Abecasis, Anne-Mieke Vandamme, Ricardo J. Camacho, and Marcelo A. Soares

Discordant genotypic interpretation and phenotypic role of protease mutations in HIV-1 subtypes B and G
JAC Advance Access published on January 10, 2009
J. Antimicrob. Chemother. 2009 63: 593-599; doi:10.1093/jac/dkn526 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Tiziano Allice, Alessandro Busca, Franco Locatelli, Michele Falda, Fabrizia Pittaluga, and Valeria Ghisetti

Valganciclovir as pre-emptive therapy for cytomegalovirus infection post-allogenic stem cell transplantation: implications for the emergence of drug-resistant cytomegalovirus
JAC Advance Access published on January 15, 2009
J. Antimicrob. Chemother. 2009 63: 600-608; doi:10.1093/jac/dkn521 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Klaus Kaier, Uwe Frank, Christian Hagist, Andreas Conrad, and Elisabeth Meyer

The impact of antimicrobial drug consumption and alcohol-based hand rub use on the emergence and spread of extended-spectrum β-lactamase-producing strains: a time-series analysis
JAC Advance Access published on January 16, 2009
J. Antimicrob. Chemother. 2009 63: 609-614; doi:10.1093/jac/dkn534 [Abstract] [Full Text] [PDF] [Request Permissions]  

Research letters

Andrew J. Buckton, Damayanti P. Prabhu, Patricia A. Cane, and Deenan Pillay

No evidence for cross-contamination of dried blood spots excised using an office hole-punch for HIV-1 drug resistance genotyping
JAC Advance Access published on January 21, 2009
J. Antimicrob. Chemother. 2009 63: 615-616; doi:10.1093/jac/dkn518 [Extract] [Full Text] [PDF] [Request Permissions]  

Elisabete Machado, Teresa M. Coque, Rafael Cantón, João Carlos Sousa, Diana Silva, Mayra Ramos, Joana Rocha, Helena Ferreira, and Luísa Peixe

Leakage into Portuguese aquatic environments of extended-spectrum-β-lactamase-producing Enterobacteriaceae
JAC Advance Access published on December 24, 2008
J. Antimicrob. Chemother. 2009 63: 616-618; doi:10.1093/jac/dkn510 [Extract] [Full Text] [PDF] [Request Permissions]  

Temenuga Stoeva, Paul G. Higgins, Encho Savov, Rumyana Markovska, Ivan Mitov, and Harald Seifert

Nosocomial spread of OXA-23 and OXA-58 β-lactamase-producing Acinetobacter baumannii in a Bulgarian hospital
JAC Advance Access published on January 15, 2009
J. Antimicrob. Chemother. 2009 63: 618-620; doi:10.1093/jac/dkn537 [Extract] [Full Text] [PDF] [Request Permissions]  

Aleksandra K. Wierzbowski, James A. Karlowsky, Daryl J. Hoban, and George G. Zhanel

In vitro activity of the investigational ketolide cethromycin against macrolide- and penicillin-resistant Streptococcus pneumoniae: review of the 1998 to 2006 Canadian Respiratory Organism Susceptibility Study (CROSS)
JAC Advance Access published on January 16, 2009
J. Antimicrob. Chemother. 2009 63: 620-622; doi:10.1093/jac/dkn532 [Extract] [Full Text] [PDF] [Request Permissions]  

Daniel P. Webster, Stewart Griffiths, and Ian C. J. W. Bowler

Failure of linezolid therapy for post-neurosurgical meningitis due to Enterococcus faecium
JAC Advance Access published on January 6, 2009
J. Antimicrob. Chemother. 2009 63: 622-623; doi:10.1093/jac/dkn519 [Extract] [Full Text] [PDF] [Request Permissions]  

Anna Turkova, Colin Ball, Susanna Gilmour-White, Mohamed Rela, and Giorgina Mieli-Vergani

A paediatric case of acute liver failure associated with efavirenz-based highly active antiretroviral therapy and effective use of raltegravir in combination antiretroviral treatment after liver transplantation
JAC Advance Access published on January 22, 2009
J. Antimicrob. Chemother. 2009 63: 623-625; doi:10.1093/jac/dkn548 [Extract] [Full Text] [PDF] [Request Permissions]  

Claudio Annaloro, Cecilia Olivares, Patrizia Usardi, Francesco Onida, Aldo Della Volpe, Elena Tagliaferri, and Giorgio Lambertenghi Deliliers

Retrospective evaluation of amphotericin B deoxycholate toxicity in a single centre series of haematopoietic stem cell transplantation recipients
JAC Advance Access published on January 21, 2009
J. Antimicrob. Chemother. 2009 63: 625-626; doi:10.1093/jac/dkn549 [Extract] [Full Text] [PDF] [Request Permissions]  

Letters to the Editor

Vincent H. Tam, JingGuo Hou, Andrea L. Kwa, and Randall A. Prince

Comment on: Development and validation of a reversed-phase high-performance liquid chromatography assay for polymyxin B in human plasma
JAC Advance Access published on November 19, 2008
J. Antimicrob. Chemother. 2009 63: 627-628; doi:10.1093/jac/dkn483 [Extract] [Full Text] [PDF] [Request Permissions]  

Jian Li, Roger L. Nation, Guoying Cao, Feda' Emad Atta Ali, Francis Chiu, and Alexandre P. Zavascki

Development and validation of a reversed-phase high-performance liquid chromatography assay for polymyxin B in human plasma—authors' response
JAC Advance Access published on January 8, 2009
J. Antimicrob. Chemother. 2009 63: 628-629; doi:10.1093/jac/dkn524 [Extract] [Full Text] [PDF] [Request Permissions]  

D. C. Shanson

Comment on: New guidance from NICE regarding antibiotic prophylaxis for infective endocarditis – response by the BSAC Working Party
JAC Advance Access published on January 15, 2009
J. Antimicrob. Chemother. 2009 63: 629-630; doi:10.1093/jac/dkn536 [Extract] [Full Text] [PDF] [Request Permissions]  

Klaus Kaier and Uwe Frank

An econometric view of the dynamic relationship between antibiotic consumption, hand disinfection and methicillin-resistant Staphylococcus aureus
JAC Advance Access published on December 24, 2008
J. Antimicrob. Chemother. 2009 63: 630-631; doi:10.1093/jac/dkn517 [Extract] [Full Text] [PDF] [Request Permissions]  

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