Journal of Antimicrobial Chemotherapy

Leading article

Get checked abstract Anna Maria Geretti

Shifting paradigms: the resistance profile of etravirine
JAC Advance Access published on June 19, 2008
J. Antimicrob. Chemother. 2008 62: 643-647; doi:10.1093/jac/dkn248 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Review

Get checked abstract Jane E. Mallewa, Edmund Wilkins, Javier Vilar, Macpherson Mallewa, Dominic Doran, David Back, and Munir Pirmohamed

HIV-associated lipodystrophy: a review of underlying mechanisms and therapeutic options
JAC Advance Access published on June 18, 2008
J. Antimicrob. Chemother. 2008 62: 648-660; doi:10.1093/jac/dkn251 [Abstract] [Full Text] [PDF] [Request Permissions]  

Systematic review

Get checked abstract Ilias I. Siempos, Konstantinos Z. Vardakas, Petros Kopterides, and Matthew E. Falagas

Adjunctive therapies for community-acquired pneumonia: a systematic review
JAC Advance Access published on July 18, 2008
J. Antimicrob. Chemother. 2008 62: 661-668; doi:10.1093/jac/dkn283 [Abstract] [Full Text] [PDF] [Request Permissions]  

Original research

Get checked abstract Maria S. Ramirez, T. Richard Parenteau, Daniela Centron, and Marcelo E. Tolmasky

Functional characterization of Tn1331 gene cassettes
JAC Advance Access published on July 16, 2008
J. Antimicrob. Chemother. 2008 62: 669-673; doi:10.1093/jac/dkn279 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Olusegun O. Soge, Nicola K. Beck, Teresa M. White, David B. No, and Marilyn C. Roberts

A novel transposon, Tn6009, composed of a Tn916 element linked with a Staphylococcus aureus mer operon
JAC Advance Access published on June 25, 2008
J. Antimicrob. Chemother. 2008 62: 674-680; doi:10.1093/jac/dkn255 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Lourdes Garcia-Migura, Henrik Hasman, Christina Svendsen, and Lars Bogø Jensen

Relevance of hot spots in the evolution and transmission of Tn1546 in glycopeptide-resistant Enterococcus faecium (GREF) from broiler origin
JAC Advance Access published on June 25, 2008
J. Antimicrob. Chemother. 2008 62: 681-687; doi:10.1093/jac/dkn265 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Mohammed Salim Ammor, Ana Belén Flórez, Pablo Álvarez-Martín, Abelardo Margolles, and Baltasar Mayo

Analysis of tetracycline resistance tet(W) genes and their flanking sequences in intestinal Bifidobacterium species
JAC Advance Access published on July 8, 2008
J. Antimicrob. Chemother. 2008 62: 688-693; doi:10.1093/jac/dkn280 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Bjørg Haldorsen, Bettina Aasnaes, Kristin H. Dahl, Anne-Merethe Hanssen, Gunnar S. Simonsen, Timothy R. Walsh, Arnfinn Sundsfjord, and Eirik W. Lundblad

The AmpC phenotype in Norwegian clinical isolates of Escherichia coli is associated with an acquired ISEcp1-like ampC element or hyperproduction of the endogenous AmpC
JAC Advance Access published on June 26, 2008
J. Antimicrob. Chemother. 2008 62: 694-702; doi:10.1093/jac/dkn257 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Nahid Karami, Charles Hannoun, Ingegerd Adlerberth, and Agnes E. Wold

Colonization dynamics of ampicillin-resistant Escherichia coli in the infantile colonic microbiota
JAC Advance Access published on June 25, 2008
J. Antimicrob. Chemother. 2008 62: 703-708; doi:10.1093/jac/dkn263 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract D. M. O'Sullivan, T. D. McHugh, and S. H. Gillespie

The effect of oxidative stress on the mutation rate of Mycobacterium tuberculosis with impaired catalase/peroxidase function
JAC Advance Access published on June 24, 2008
J. Antimicrob. Chemother. 2008 62: 709-712; doi:10.1093/jac/dkn259 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Mekonnen Kurabachew, Stephen H. J. Lu, Philipp Krastel, Esther K. Schmitt, Bangalore L. Suresh, Anne Goh, John E. Knox, Ngai Ling Ma, Jan Jiricek, David Beer, Michael Cynamon, Frank Petersen, Veronique Dartois, Thomas Keller, Thomas Dick, and Vasan K. Sambandamurthy

Lipiarmycin targets RNA polymerase and has good activity against multidrug-resistant strains of Mycobacterium tuberculosis
JAC Advance Access published on June 27, 2008
J. Antimicrob. Chemother. 2008 62: 713-719; doi:10.1093/jac/dkn269 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract John E. Mott, Bailin A. Shaw, James F. Smith, Paul D. Bonin, Donna L. Romero, Keith R. Marotti, and Alita A. Miller

Resistance mapping and mode of action of a novel class of antibacterial anthranilic acids: evidence for disruption of cell wall biosynthesis
JAC Advance Access published on June 19, 2008
J. Antimicrob. Chemother. 2008 62: 720-729; doi:10.1093/jac/dkn261 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Mateja Zorko and Roman Jerala

Alexidine and chlorhexidine bind to lipopolysaccharide and lipoteichoic acid and prevent cell activation by antibiotics
JAC Advance Access published on July 16, 2008
J. Antimicrob. Chemother. 2008 62: 730-737; doi:10.1093/jac/dkn270 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Peter L. Anderson, Tracy King, Jia-Hua Zheng, and Samantha MaWhinney

Cytokine and sex hormone effects on zidovudine- and lamivudine-triphosphate concentrations in vitro
JAC Advance Access published on June 20, 2008
J. Antimicrob. Chemother. 2008 62: 738-745; doi:10.1093/jac/dkn247 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract I. Raad, R. Reitzel, Y. Jiang, R. F. Chemaly, T. Dvorak, and R. Hachem

Anti-adherence activity and antimicrobial durability of anti-infective-coated catheters against multidrug-resistant bacteria
JAC Advance Access published on July 23, 2008
J. Antimicrob. Chemother. 2008 62: 746-750; doi:10.1093/jac/dkn281 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Barira Islam, Shahper N. Khan, Irfanul Haque, M. Alam, M. Mushfiq, and Asad U. Khan

Novel anti-adherence activity of mulberry leaves: inhibition of Streptococcus mutans biofilm by 1-deoxynojirimycin isolated from Morus alba
JAC Advance Access published on June 18, 2008
J. Antimicrob. Chemother. 2008 62: 751-757; doi:10.1093/jac/dkn253 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Luciene M. Coelho, Roseli Aquino-Ferreira, Cláudia M.Leite Maffei, and Nilce M. Martinez-Rossi

In vitro antifungal drug susceptibilities of dermatophytes microconidia and arthroconidia
JAC Advance Access published on June 13, 2008
J. Antimicrob. Chemother. 2008 62: 758-761; doi:10.1093/jac/dkn245 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Rachael O'Connor, Simon D. Baines, Jane Freeman, and Mark H. Wilcox

In vitro susceptibility of genotypically distinct and clonal Clostridium difficile strains to oritavancin
JAC Advance Access published on July 7, 2008
J. Antimicrob. Chemother. 2008 62: 762-765; doi:10.1093/jac/dkn276 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract N. Woodford, M. Afzal-Shah, M. Warner, and D. M. Livermore

In vitro activity of retapamulin against Staphylococcus aureus isolates resistant to fusidic acid and mupirocin
JAC Advance Access published on June 19, 2008
J. Antimicrob. Chemother. 2008 62: 766-768; doi:10.1093/jac/dkn266 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract David T. Bearden, George P. Allen, and J. Mark Christensen

Comparative in vitro activities of topical wound care products against community-associated methicillin-resistant Staphylococcus aureus
JAC Advance Access published on June 30, 2008
J. Antimicrob. Chemother. 2008 62: 769-772; doi:10.1093/jac/dkn272 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Juan-Ignacio Alós, Ana García-Cañas, Paloma García-Hierro, and Francisco Rodríguez-Salvanés

Vancomycin MICs did not creep in Staphylococcus aureus isolates from 2002 to 2006 in a setting with low vancomycin usage
JAC Advance Access published on June 13, 2008
J. Antimicrob. Chemother. 2008 62: 773-775; doi:10.1093/jac/dkn246 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Shamez Ladhani, Paul T. Heath, Mary E. Ramsay, and Mary P. E. Slack

Changes in antibiotic resistance rates of invasive Haemophilus influenzae isolates in England and Wales over the last 20 years
JAC Advance Access published on July 28, 2008
J. Antimicrob. Chemother. 2008 62: 776-779; doi:10.1093/jac/dkn274 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Shekman L. Wong, Steven L. Barriere, Michael M. Kitt, and Michael R. Goldberg

Multiple-dose pharmacokinetics of intravenous telavancin in healthy male and female subjects
JAC Advance Access published on June 26, 2008
J. Antimicrob. Chemother. 2008 62: 780-783; doi:10.1093/jac/dkn273 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract José Moltó, Marta Valle, Cristina Miranda, Samandhy Cedeño, José Miranda, José Ramón Santos, Eugenia Negredo, Josep Vilaró, Joan Costa, and Bonaventura Clotet

Once- or twice-daily dosing of nevirapine in HIV-infected adults: a population pharmacokinetics approach
JAC Advance Access published on June 30, 2008
J. Antimicrob. Chemother. 2008 62: 784-792; doi:10.1093/jac/dkn268 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Manuel Crespo, José A. Mira, Juan A. Pineda, Eva Van den Eynde, María J. Ríos-Villegas, Antonio Collado, José A. Girón-González, Luis F. López-Cortés, Mercedes González-Serrano, Antonio Rivero, Dolores Merino, and Juan I. Esteban

Efficacy of pegylated interferon and ribavirin for retreatment of chronic HCV infection in HIV co-infected patients failing a previous standard interferon-based regimen
JAC Advance Access published on June 21, 2008
J. Antimicrob. Chemother. 2008 62: 793-796; doi:10.1093/jac/dkn262 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Claudine Duvivier, Jade Ghosn, Lambert Assoumou, Cathia Soulié, Gilles Peytavin, Vincent Calvez, Michèle Algarté Génin, Jean-Michel Molina, Olivier Bouchaud, Christine Katlama, and Dominique Costagliola on behalf of the ANRS 121 study group

Initial therapy with nucleoside reverse transcriptase inhibitor-containing regimens is more effective than with regimens that spare them with no difference in short-term fat distribution: Hippocampe-ANRS 121 Trial
JAC Advance Access published on July 18, 2008
J. Antimicrob. Chemother. 2008 62: 797-808; doi:10.1093/jac/dkn278 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Joanne Sanders, Alan Pithie, Peter Ganly, Lois Surgenor, Rachel Wilson, Eileen Merriman, Gail Loudon, Rhonda Judkins, and Stephen Chambers

A prospective double-blind randomized trial comparing intraluminal ethanol with heparinized saline for the prevention of catheter-associated bloodstream infection in immunosuppressed haematology patients
JAC Advance Access published on July 11, 2008
J. Antimicrob. Chemother. 2008 62: 809-815; doi:10.1093/jac/dkn284 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Inmaculada Jiménez-Nácher, Benito García, Pablo Barreiro, Sonia Rodriguez-Novoa, Judit Morello, Juan González-Lahoz, Carmen de Mendoza, and Vincent Soriano

Trends in the prescription of antiretroviral drugs and impact on plasma HIV-RNA measurements
JAC Advance Access published on June 21, 2008
J. Antimicrob. Chemother. 2008 62: 816-822; doi:10.1093/jac/dkn252 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Katiuska Miliani, François L'Hériteau, Serge Alfandari, Isabelle Arnaud, Yannick Costa, Elisabeth Delière, Anne Carbonne, and Pascal Astagneau on behalf on the Antimicrobial Surveillance Network

Specific control measures for antibiotic prescription are related to lower consumption in hospitals: results from a French multicentre pilot study
JAC Advance Access published on July 25, 2008
J. Antimicrob. Chemother. 2008 62: 823-829; doi:10.1093/jac/dkn277 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Michael A. Borg, Peter Zarb, Matus Ferech, and Herman Goossens on behalf of the ARMed Project Group

Antibiotic consumption in southern and eastern Mediterranean hospitals: results from the ARMed project
JAC Advance Access published on June 30, 2008
J. Antimicrob. Chemother. 2008 62: 830-836; doi:10.1093/jac/dkn260 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Stefan P. Kuster, Christian Ruef, Alfred K. Bollinger, Bruno Ledergerber, Andreas Hintermann, Clau Deplazes, Lutz Neuber, and Rainer Weber

Correlation between case mix index and antibiotic use in hospitals
JAC Advance Access published on July 9, 2008
J. Antimicrob. Chemother. 2008 62: 837-842; doi:10.1093/jac/dkn275 [Abstract] [Full Text] [PDF] [Request Permissions]  

Research letters

Amy Gassama Sow, Mamadou Hadi Diallo, Martine Gatet, François Denis, Awa Aïdara-Kane, and Marie-Cécile Ploy

Description of an unusual class 2 integron in Shigella sonnei isolates in Senegal (sub-Saharan Africa)
JAC Advance Access published on June 18, 2008
J. Antimicrob. Chemother. 2008 62: 843-844; doi:10.1093/jac/dkn264 [Extract] [Full Text] [PDF] [Request Permissions]  

Yvonne Agersø, Camilla H. Lester, Lone J. Porsbo, Iben Ørsted, Hanne-Dorthe Emborg, Katharina E. P. Olsen, Lars B. Jensen, Ole E. Heuer, Niels Frimodt-Møller, Frank M. Aarestrup, and Anette M. Hammerum

Vancomycin-resistant Enterococcus faecalis isolates from a Danish patient and two healthy human volunteers are possibly related to isolates from imported turkey meat
JAC Advance Access published on June 26, 2008
J. Antimicrob. Chemother. 2008 62: 844-845; doi:10.1093/jac/dkn271 [Extract] [Full Text] [PDF] [Request Permissions]  

E. Botelho-Nevers, Leon Espinosa, D. Raoult, and J.-M. Rolain

Lovastatin, but not pravastatin, limits in vitro infection due to Coxiella burnetii
JAC Advance Access published on June 30, 2008
J. Antimicrob. Chemother. 2008 62: 845-847; doi:10.1093/jac/dkn282 [Extract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Julie Bresson, Catherine Paugam-Burtz, Julien Josserand, Christophe Bardin, Jean Mantz, and Sebastian Pease

Cefepime overdosage with neurotoxicity recovered by high-volume haemofiltration
JAC Advance Access published on June 18, 2008
J. Antimicrob. Chemother. 2008 62: 849-850; doi:10.1093/jac/dkn256 [Extract] [Full Text] [PDF] [Request Permissions]  

Shellee A. Grim, Lisa Rene, Sandeep Gupta, and Nina M. Clark

Safety of linezolid in patients with baseline thrombocytopenia
JAC Advance Access published on July 2, 2008
J. Antimicrob. Chemother. 2008 62: 850-851; doi:10.1093/jac/dkn285 [Extract] [Full Text] [PDF] [Request Permissions]  

Erratum

Jasper van der Lugt, Reshma Saskia Autar, Sasiwimol Ubolyam, Evian Fernandez Garcia, Jongkol Sankote, Anchalee Avihingsanon, Theshinee Chuenyam, David A. Cooper, Joep Lange, Praphan Phanuphak, Ferdinand Wit, Kiat Ruxrungtham, and David Burger on behalf of the HIV-NAT 019 Study Team

Pharmacokinetics and short-term efficacy of a double-boosted protease inhibitor regimen in treatment-naive HIV-1-infected adults
JAC Advance Access published on August 15, 2008
J. Antimicrob. Chemother. 2008 62: 852; doi:10.1093/jac/dkn342 [Extract] [Full Text] [PDF] [Request Permissions]  

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