Journal of Antimicrobial Chemotherapy

Leading article

Get checked abstract Linos Vandekerckhove, Chris Verhofstede, and Dirk Vogelaers

Maraviroc: integration of a new antiretroviral drug class into clinical practice
JAC Advance Access published on April 9, 2008
J. Antimicrob. Chemother. 2008 61: 1187-1190; doi:10.1093/jac/dkn130 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Systematic review

Get checked abstract Massimo Franchini, Carlo Mengoli, Dino Veneri, Romualdo Mazzi, Giuseppe Lippi, and Mario Cruciani

Treatment of chronic hepatitis C in haemophilic patients with interferon and ribavirin: a meta-analysis
JAC Advance Access published on March 19, 2008
J. Antimicrob. Chemother. 2008 61: 1191-1200; doi:10.1093/jac/dkn119 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Original research

Get checked abstract Luis M. F. Gonzalez, André F. Santos, Ana B. Abecasis, Kristel Van Laethem, Esmeralda A. Soares, Koen Deforche, Amilcar Tanuri, Ricardo Camacho, Anne-Mieke Vandamme, and Marcelo A. Soares

Impact of HIV-1 protease mutations A71V/T and T74S on M89I/V-mediated protease inhibitor resistance in subtype G isolates
JAC Advance Access published on March 20, 2008
J. Antimicrob. Chemother. 2008 61: 1201-1204; doi:10.1093/jac/dkn099 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Sophie Le Pogam, Amritha Seshaadri, Alan Kosaka, Sophie Chiu, Hyunsoon Kang, Steven Hu, Sonal Rajyaguru, Julian Symons, Nick Cammack, and Isabel Nájera

Existence of hepatitis C virus NS5B variants naturally resistant to non-nucleoside, but not to nucleoside, polymerase inhibitors among untreated patients
JAC Advance Access published on March 13, 2008
J. Antimicrob. Chemother. 2008 61: 1205-1216; doi:10.1093/jac/dkn085 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Douglas McIntosh, Michelle Cunningham, Baijing Ji, Frank A. Fekete, Erin M. Parry, Sarah E. Clark, Zachary B. Zalinger, Ilana C. Gilg, G. Russell Danner, Keith A. Johnson, Mike Beattie, and Rachael Ritchie

Transferable, multiple antibiotic and mercury resistance in Atlantic Canadian isolates of Aeromonas salmonicida subsp. salmonicida is associated with carriage of an IncA/C plasmid similar to the Salmonella enterica plasmid pSN254
JAC Advance Access published on March 28, 2008
J. Antimicrob. Chemother. 2008 61: 1221-1228; doi:10.1093/jac/dkn123 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Aurora García-Fernández, Giuseppina Chiaretto, Alessia Bertini, Laura Villa, Daniela Fortini, Antonia Ricci, and Alessandra Carattoli

Multilocus sequence typing of IncI1 plasmids carrying extended-spectrum β-lactamases in Escherichia coli and Salmonella of human and animal origin
JAC Advance Access published on March 26, 2008
J. Antimicrob. Chemother. 2008 61: 1229-1233; doi:10.1093/jac/dkn131 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Jiunn-Jong Wu, Wen-Chien Ko, Hsiu-Mei Wu, and Jing-Jou Yan

Prevalence of Qnr determinants among bloodstream isolates of Escherichia coli and Klebsiella pneumoniae in a Taiwanese Hospital, 1999–2005
JAC Advance Access published on March 20, 2008
J. Antimicrob. Chemother. 2008 61: 1234-1239; doi:10.1093/jac/dkn111 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract J. M. Rodríguez-Martínez, C. Velasco, A. Briales, I. García, M. C. Conejo, and A. Pascual

Qnr-like pentapeptide repeat proteins in Gram-positive bacteria
JAC Advance Access published on March 13, 2008
J. Antimicrob. Chemother. 2008 61: 1240-1243; doi:10.1093/jac/dkn115 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract S. Lavilla, J. J. González-López, E. Miró, A. Domínguez, M. Llagostera, R. M. Bartolomé, B. Mirelis, F. Navarro, and G. Prats

Dissemination of extended-spectrum β-lactamase-producing bacteria: the food-borne outbreak lesson
JAC Advance Access published on March 12, 2008
J. Antimicrob. Chemother. 2008 61: 1244-1251; doi:10.1093/jac/dkn093 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Emmanouil Angelakis, Silpak Biswas, Carmel Taylor, Didier Raoult, and Jean-Marc Rolain

Heterogeneity of susceptibility to fluoroquinolones in Bartonella isolates from Australia reveals a natural mutation in gyrA
JAC Advance Access published on March 10, 2008
J. Antimicrob. Chemother. 2008 61: 1252-1255; doi:10.1093/jac/dkn094 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Marina Sánchez-Hidalgo, Manuel Martínez-Bueno, Ana M Fernández-Escamilla, Eva Valdivia, Luis Serrano, and Mercedes Maqueda

Effect of replacing glutamic residues upon the biological activity and stability of the circular enterocin AS-48
JAC Advance Access published on April 1, 2008
J. Antimicrob. Chemother. 2008 61: 1256-1265; doi:10.1093/jac/dkn126 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Kazuhisa Ouhara, Hitoshi Komatsuzawa, Toshihisa Kawai, Hiromi Nishi, Tamaki Fujiwara, Yoshihiro Fujiue, Masao Kuwabara, Koji Sayama, Koji Hashimoto, and Motoyuki Sugai

Increased resistance to cationic antimicrobial peptide LL-37 in methicillin-resistant strains of Staphylococcus aureus
JAC Advance Access published on March 26, 2008
J. Antimicrob. Chemother. 2008 61: 1266-1269; doi:10.1093/jac/dkn106 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Ashwani Kumar, Inshad Ali Khan, Surrinder Koul, Jawahir Lal Koul, Subhash Chandra Taneja, Intzar Ali, Furqan Ali, Sandeep Sharma, Zahid Mehmood Mirza, Manoj Kumar, Pyare Lal Sangwan, Pankaj Gupta, Niranjan Thota, and Ghulam Nabi Qazi

Novel structural analogues of piperine as inhibitors of the NorA efflux pump of Staphylococcus aureus
JAC Advance Access published on March 10, 2008
J. Antimicrob. Chemother. 2008 61: 1270-1276; doi:10.1093/jac/dkn088 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Gerald Müller and Axel Kramer

Biocompatibility index of antiseptic agents by parallel assessment of antimicrobial activity and cellular cytotoxicity
JAC Advance Access published on March 25, 2008
J. Antimicrob. Chemother. 2008 61: 1281-1287; doi:10.1093/jac/dkn125 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Boyan Bonev, James Hooper, and Judicaël Parisot

Principles of assessing bacterial susceptibility to antibiotics using the agar diffusion method
JAC Advance Access published on March 12, 2008
J. Antimicrob. Chemother. 2008 61: 1295-1301; doi:10.1093/jac/dkn090 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Brian G. Oliver, Peter M. Silver, and Theodore C. White

Polyene susceptibility is dependent on nitrogen source in the opportunistic pathogen Candida albicans
JAC Advance Access published on March 13, 2008
J. Antimicrob. Chemother. 2008 61: 1302-1308; doi:10.1093/jac/dkn101 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Erja Chryssanthou, Alissha Loebig, and Jan Sjölin

Post-antifungal effect of amphotericin B and voriconazole against germinated Aspergillus fumigatus conidia
JAC Advance Access published on March 26, 2008
J. Antimicrob. Chemother. 2008 61: 1309-1311; doi:10.1093/jac/dkn129 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Anna Maria Tortorano, Anna Prigitano, Giovanna Dho, Renata Piccinini, Valentina Daprà, and Maria Anna Viviani

In vitro activity of conventional antifungal drugs and natural essences against the yeast-like alga Prototheca
JAC Advance Access published on March 12, 2008
J. Antimicrob. Chemother. 2008 61: 1312-1314; doi:10.1093/jac/dkn107 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Andrea Djie-Maletz, Klaus Reither, Stephen Danour, Louis Anyidoho, Eiman Saad, Francis Danikuu, Peter Ziniel, Thomas Weitzel, Jutta Wagner, Ulrich Bienzle, Klaus Stark, Andrew Seidu-Korkor, Frank P. Mockenhaupt, and Ralf Ignatius

High rate of resistance to locally used antibiotics among enteric bacteria from children in Northern Ghana
JAC Advance Access published on March 19, 2008
J. Antimicrob. Chemother. 2008 61: 1315-1318; doi:10.1093/jac/dkn108 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract H. R. Martins, L. M. Figueiredo, J. C. O. Valamiel-Silva, C. M. Carneiro, G. L. L. Machado-Coelho, D. M. Vitelli-Avelar, M. T. Bahia, O. A. Martins-Filho, A. M. Macedo, and M. Lana

Persistence of PCR-positive tissue in benznidazole-treated mice with negative blood parasitological and serological tests in dual infections with Trypanosoma cruzi stocks from different genotypes
JAC Advance Access published on March 13, 2008
J. Antimicrob. Chemother. 2008 61: 1319-1327; doi:10.1093/jac/dkn092 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Kyriaki Kanellakopoulou, Alexandra Pagoulatou, Konstantinos Stroumpoulis, Marianthi Vafiadou, Hariklia Kranidioti, Helen Giamarellou, and Evangelos J. Giamarellos-Bourboulis

Pharmacokinetics of moxifloxacin in non-inflamed cerebrospinal fluid of humans: implication for a bactericidal effect
JAC Advance Access published on March 18, 2008
J. Antimicrob. Chemother. 2008 61: 1328-1331; doi:10.1093/jac/dkn110 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract N. Perrottet, C. Robatel, P. Meylan, M. Pascual, J. P. Venetz, J. D. Aubert, M. M. Berger, L. A. Decosterd, and T. Buclin

Disposition of valganciclovir during continuous renal replacement therapy in two lung transplant recipients
JAC Advance Access published on March 15, 2008
J. Antimicrob. Chemother. 2008 61: 1332-1335; doi:10.1093/jac/dkn102 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract U. Wintergerst, F. Hoffmann, A. Jansson, G. Notheis, K. Huß, M. Kurowski, and D. Burger

Antiviral efficacy, tolerability and pharmacokinetics of efavirenz in an unselected cohort of HIV-infected children
JAC Advance Access published on March 13, 2008
J. Antimicrob. Chemother. 2008 61: 1336-1339; doi:10.1093/jac/dkn112 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Jintanat Ananworanich, Reto Nuesch, Hélène C. F. Côté, Stephen J. Kerr, Andrew Hill, Thidarat Jupimai, Naphassanant Laopraynak, Sukontha Saenawat, Kiat Ruxrungtham, and Bernard Hirschel

Changes in metabolic toxicity after switching from stavudine/didanosine to tenofovir/lamivudine—a Staccato trial substudy
JAC Advance Access published on March 12, 2008
J. Antimicrob. Chemother. 2008 61: 1340-1343; doi:10.1093/jac/dkn097 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Jade Ghosn, Marie-Laure Chaix, Gilles Peytavin, Jean-Louis Bresson, Julie Galimand, Pierre-Marie Girard, François Raffi, Isabelle Cohen-Codar, Jean-François Delfraissy, and Christine Rouzioux

Absence of HIV-1 shedding in male genital tract after 1 year of first-line lopinavir/ritonavir alone or in combination with zidovudine/lamivudine
JAC Advance Access published on March 13, 2008
J. Antimicrob. Chemother. 2008 61: 1344-1347; doi:10.1093/jac/dkn098 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Pere Domingo, Ignacio Suárez-Lozano, Ferran Torres, Ramón Teira, José Lopez-Aldeguer, Francesc Vidal, Agustín Muñoz, Pompeyo Viciana, Fernando Lozano, Antonio Vergara, Bernadino Roca, Ma Luisa García Alcalde, Jaime Cosín, Alberto Terrón, Ma José Galindo, Paloma Geijo, Esteban Ribera, Juan Gonzalez, Trinitario Sanchez, Juan Ramón Lacalle, and Myriam Garrido

First-line antiretroviral therapy with efavirenz or lopinavir/ritonavir plus two nucleoside analogues: the SUSKA study, a non-randomized comparison from the VACH cohort
JAC Advance Access published on March 20, 2008
J. Antimicrob. Chemother. 2008 61: 1348-1358; doi:10.1093/jac/dkn121 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Federico Pulido, Rafael Delgado, Ignacio Pérez-Valero, Juan González-García, Pilar Miralles, Alberto Arranz, Asunción Hernando, and José R. Arribas

Long-term (4 years) efficacy of lopinavir/ritonavir monotherapy for maintenance of HIV suppression
JAC Advance Access published on March 13, 2008
J. Antimicrob. Chemother. 2008 61: 1359-1361; doi:10.1093/jac/dkn103 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract B. Masquelier, K. L. Assoumou, D. Descamps, L. Bocket, J. Cottalorda, A. Ruffault, A. G. Marcelin, L. Morand-Joubert, C. Tamalet, C. Charpentier, G. Peytavin, Z. Antoun, F. Brun-Vézinet, and D. Costagliola on behalf of the ANRS Resistance Study Group

Clinically validated mutation scores for HIV-1 resistance to fosamprenavir/ritonavir
JAC Advance Access published on April 4, 2008
J. Antimicrob. Chemother. 2008 61: 1362-1368; doi:10.1093/jac/dkn127 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract M. S. Oliveira, G. V. B. Prado, S. F. Costa, R. S. Grinbaum, and A. S. Levin

Ampicillin/sulbactam compared with polymyxins for the treatment of infections caused by carbapenem-resistant Acinetobacter spp.
JAC Advance Access published on March 25, 2008
J. Antimicrob. Chemother. 2008 61: 1369-1375; doi:10.1093/jac/dkn128 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Jonas Marschall, Denis Agniel, Victoria J. Fraser, Joshua Doherty, and David K. Warren

Gram-negative bacteraemia in non-ICU patients: factors associated with inadequate antibiotic therapy and impact on outcomes
JAC Advance Access published on March 15, 2008
J. Antimicrob. Chemother. 2008 61: 1376-1383; doi:10.1093/jac/dkn104 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Céline Pulcini, Sylviane Defres, Ila Aggarwal, Dilip Nathwani, and Peter Davey

Design of a ‘day 3 bundle’ to improve the reassessment of inpatient empirical antibiotic prescriptions
JAC Advance Access published on March 26, 2008
J. Antimicrob. Chemother. 2008 61: 1384-1388; doi:10.1093/jac/dkn113 [Abstract] [Full Text] [PDF] [Request Permissions]  

Research letters

A. Zioga, J. M. Whichard, K. J. Joyce, E. Tzelepi, L. S. Tzouvelekis, and V. Miriagou

Evidence for chromosomal and plasmid location of CMY-2 cephalosporinase gene in Salmonella serotype Typhimurium
JAC Advance Access published on March 18, 2008
J. Antimicrob. Chemother. 2008 61: 1389-1390; doi:10.1093/jac/dkn116 [Extract] [Full Text] [PDF] [Request Permissions]  

S. Dégrange, H. Renaudin, A. Charron, S. Pereyre, C. Bébéar, and C. M. Bébéar

Reduced susceptibility to tetracyclines is associated in vitro with the presence of 16S rRNA mutations in Mycoplasma hominis and Mycoplasma pneumoniae
JAC Advance Access published on March 19, 2008
J. Antimicrob. Chemother. 2008 61: 1390-1392; doi:10.1093/jac/dkn118 [Extract] [Full Text] [PDF] [Request Permissions]  

Laurent Poirel, Thomas Bruderer, Reno Frei, Sandrine Bernabeu, Peter Graber, and Patrice Nordmann

Multidrug-resistant Providencia stuartii expressing extended-spectrum β-lactamase PER-1, originating in Kosovo
JAC Advance Access published on March 10, 2008
J. Antimicrob. Chemother. 2008 61: 1392-1393; doi:10.1093/jac/dkn091 [Extract] [Full Text] [PDF] [Request Permissions]  

Muzaheed, Yohei Doi, Jennifer M. Adams-Haduch, Andrea Endimiani, Hanna E. Sidjabat, Subhaschandra M. Gaddad, and David L. Paterson

High prevalence of CTX-M-15-producing Klebsiella pneumoniae among inpatients and outpatients with urinary tract infection in Southern India
JAC Advance Access published on March 20, 2008
J. Antimicrob. Chemother. 2008 61: 1393-1394; doi:10.1093/jac/dkn109 [Extract] [Full Text] [PDF] [Request Permissions]  

Alicia I. Hidron, Audrey N. Schuetz, Frederick S. Nolte, Carolyn V. Gould, and Melissa K. Osborn

Daptomycin resistance in Enterococcus faecalis prosthetic valve endocarditis
JAC Advance Access published on March 15, 2008
J. Antimicrob. Chemother. 2008 61: 1394-1396; doi:10.1093/jac/dkn105 [Extract] [Full Text] [PDF] [Request Permissions]  

Ewout J. Hoorn and Robert Zietse

Severe hypokalaemia caused by flucloxacillin
JAC Advance Access published on April 3, 2008
J. Antimicrob. Chemother. 2008 61: 1396-1398; doi:10.1093/jac/dkn117 [Extract] [Full Text] [PDF] [Request Permissions]  

Kristjan O. Helgason, Alison H. Thomson, and Craig Ferguson

A review of vancomycin therapeutic drug monitoring recommendations in Scotland
JAC Advance Access published on March 18, 2008
J. Antimicrob. Chemother. 2008 61: 1398-1399; doi:10.1093/jac/dkn114 [Extract] [Full Text] [PDF] [Request Permissions]  

Letter to the Editor

David R. Nalin

Comment on: Unexpected antimicrobial effect of statins
JAC Advance Access published on March 4, 2008
J. Antimicrob. Chemother. 2008 61: 1400; doi:10.1093/jac/dkn089 [Extract] [Full Text] [PDF] [Request Permissions]  

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