Journal of Antimicrobial Chemotherapy

Leading articles

Get checked abstract I. M. Gould

Antibiotic policies to control hospital-acquired infection
JAC Advance Access published on February 14, 2008
J. Antimicrob. Chemother. 2008 61: 763-765; doi:10.1093/jac/dkn039 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Julie Sheldon and Vincent Soriano

Hepatitis B virus escape mutants induced by antiviral therapy
JAC Advance Access published on January 24, 2008
J. Antimicrob. Chemother. 2008 61: 766-768; doi:10.1093/jac/dkn014 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Review

Get checked abstract Jonathan Shuter

Forgiveness of non-adherence to HIV-1 antiretroviral therapy
JAC Advance Access published on February 6, 2008
J. Antimicrob. Chemother. 2008 61: 769-773; doi:10.1093/jac/dkn020 [Abstract] [Full Text] [PDF] [Request Permissions]  

Systematic review

Get checked abstract Matthew E. Falagas, Gregory C. Makris, Dimitrios K. Matthaiou, and Petros I. Rafailidis

Statins for infection and sepsis: a systematic review of the clinical evidence
JAC Advance Access published on February 7, 2008
J. Antimicrob. Chemother. 2008 61: 774-785; doi:10.1093/jac/dkn019 [Abstract] [Full Text] [PDF] [Request Permissions]  

Original research

Get checked abstract E. S. Margerison, M. Maguire, D. Pillay, P. Cane, and R. C. Elston

The HIV-1 protease substitution K55R: a protease-inhibitor-associated substitution involved in restoring viral replication
JAC Advance Access published on February 4, 2008
J. Antimicrob. Chemother. 2008 61: 786-791; doi:10.1093/jac/dkm545 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Francisco José Pérez-Llarena, Mónica Cartelle, Susana Mallo, Alejandro Beceiro, Astrid Pérez, Rosa Villanueva, Antonio Romero, Richard Bonnet, and Germán Bou

Structure–function studies of arginine at position 276 in CTX-M β-lactamases
JAC Advance Access published on February 14, 2008
J. Antimicrob. Chemother. 2008 61: 792-797; doi:10.1093/jac/dkn031 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Yonghao Xu, Lamei Chen, and Chunyang Li

Susceptibility of clinical isolates of Candida species to fluconazole and detection of Candida albicans ERG11 mutations
JAC Advance Access published on January 24, 2008
J. Antimicrob. Chemother. 2008 61: 798-804; doi:10.1093/jac/dkn015 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Ana Alastruey-Izquierdo, Manuel Cuenca-Estrella, Araceli Monzón, Emilia Mellado, and Juan Luís Rodríguez-Tudela

Antifungal susceptibility profile of clinical Fusarium spp. isolates identified by molecular methods
JAC Advance Access published on February 8, 2008
J. Antimicrob. Chemother. 2008 61: 805-809; doi:10.1093/jac/dkn022 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract John Dotis, Maria Simitsopoulou, Maria Dalakiouridou, Thomai Konstantinou, Christos Panteliadis, Thomas J. Walsh, and Emmanuel Roilides

Amphotericin B formulations variably enhance antifungal activity of human neutrophils and monocytes against Fusarium solani: comparison with Aspergillus fumigatus
JAC Advance Access published on February 13, 2008
J. Antimicrob. Chemother. 2008 61: 810-817; doi:10.1093/jac/dkn036 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Yven Van Herrewege, Laurence Morellato, Anne Descours, Laetitia Aerts, Jo Michiels, Leo Heyndrickx, Loïc Martin, and Guido Vanham

CD4 mimetic miniproteins: potent anti-HIV compounds with promising activity as microbicides
JAC Advance Access published on February 12, 2008
J. Antimicrob. Chemother. 2008 61: 818-826; doi:10.1093/jac/dkn042 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Ørjan Samuelsen, Liselotte Buarø, Christian G. Giske, Gunnar S. Simonsen, Bettina Aasnæs, and Arnfinn Sundsfjord

Evaluation of phenotypic tests for the detection of metallo-β-lactamase-producing Pseudomonas aeruginosa in a low prevalence country
JAC Advance Access published on January 28, 2008
J. Antimicrob. Chemother. 2008 61: 827-830; doi:10.1093/jac/dkn016 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Kieran A. Ryan, Paul Daly, Yin Li, Carmel Hooton, and Paul W. O'Toole

Strain-specific inhibition of Helicobacter pylori by Lactobacillus salivarius and other lactobacilli
JAC Advance Access published on February 8, 2008
J. Antimicrob. Chemother. 2008 61: 831-834; doi:10.1093/jac/dkn040 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Claire Lacroix and Martine Feuilhade de Chauvin

In vitro activity of amphotericin B, itraconazole, voriconazole, posaconazole, caspofungin and terbinafine against Scytalidium dimidiatum and Scytalidium hyalinum clinical isolates
JAC Advance Access published on January 24, 2008
J. Antimicrob. Chemother. 2008 61: 835-837; doi:10.1093/jac/dkn011 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Jae-Hoon Song, Kwan Soo Ko, Ji Yoeun Suh, Won Sup Oh, Cheol-In Kang, Doo Ryeon Chung, Kyong Ran Peck, Nam Yong Lee, and Wee Gyo Lee

Clinical implications of vancomycin-resistant Enterococcus faecium (VRE) with VanD phenotype and vanA genotype
JAC Advance Access published on January 29, 2008
J. Antimicrob. Chemother. 2008 61: 838-844; doi:10.1093/jac/dkn025 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Louise Feld, Susanne Schjørring, Karin Hammer, Tine Rask Licht, Morten Danielsen, Karen Krogfelt, and Andrea Wilcks

Selective pressure affects transfer and establishment of a Lactobacillus plantarum resistance plasmid in the gastrointestinal environment
JAC Advance Access published on January 31, 2008
J. Antimicrob. Chemother. 2008 61: 845-852; doi:10.1093/jac/dkn033 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract G. R. Siragusa, G. J. Haas, P. D. Matthews, R. J. Smith, R. J. Buhr, N. M. Dale, and M. G. Wise

Antimicrobial activity of lupulone against Clostridium perfringens in the chicken intestinal tract jejunum and caecum
JAC Advance Access published on February 14, 2008
J. Antimicrob. Chemother. 2008 61: 853-858; doi:10.1093/jac/dkn024 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Carolina Serena, M. Mar Rodríguez, Marçal Mariné, F. Javier Pastor, and Josep Guarro

Micafungin combined with fluconazole, an effective therapy for murine blastoschizomycosis
JAC Advance Access published on February 13, 2008
J. Antimicrob. Chemother. 2008 61: 877-879; doi:10.1093/jac/dkn012 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Marçal Mariné, Raquel Espada, Juan Torrado, F. Javier Pastor, and Josep Guarro

Efficacy of a new formulation of amphotericin B in a murine model of disseminated infection by Candida glabrata
JAC Advance Access published on February 6, 2008
J. Antimicrob. Chemother. 2008 61: 880-883; doi:10.1093/jac/dkn028 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract M. Lucchi, B. Damle, A. Fang, P. J. de Caprariis, A. Mussi, S. P. Sanchez, G. Pasqualetti, and M. Del Tacca

Pharmacokinetics of azithromycin in serum, bronchial washings, alveolar macrophages and lung tissue following a single oral dose of extended or immediate release formulations of azithromycin
JAC Advance Access published on February 4, 2008
J. Antimicrob. Chemother. 2008 61: 884-891; doi:10.1093/jac/dkn032 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Kenichi Nomura, Norifumi Morikawa, Kazuro Ikawa, Kayo Ikeda, Yoshiko Fujimoto, Daisuke Shimizu, Kyoko Taniguchi, Kazuho Shimura, Yuko Kanbayashi, Toshiaki Komori, Yosuke Matsumoto, Naohisa Fujita, Chihiro Shimazaki, and Masafumi Taniwaki

Optimized dosage and frequency of cefozopran for patients with febrile neutropenia based on population pharmacokinetic and pharmacodynamic analysis
JAC Advance Access published on February 13, 2008
J. Antimicrob. Chemother. 2008 61: 892-900; doi:10.1093/jac/dkn038 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Sinéad Kelly, Jonathan Collins, Maureen Maguire, Catriona Gowing, Michelle Flanagan, Maria Donnelly, and Philip G. Murphy

An outbreak of colonization with linezolid-resistant Staphylococcus epidermidis in an intensive therapy unit
JAC Advance Access published on February 13, 2008
J. Antimicrob. Chemother. 2008 61: 901-907; doi:10.1093/jac/dkn043 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract A. Rodríguez Guardado, A. Blanco, V. Asensi, F. Pérez, J. C. Rial, V. Pintado, E. Bustillo, M. Lantero, E. Tenza, M. Álvarez, J. A. Maradona, and J. A. Cartón

Multidrug-resistant Acinetobacter meningitis in neurosurgical patients with intraventricular catheters: assessment of different treatments
JAC Advance Access published on February 15, 2008
J. Antimicrob. Chemother. 2008 61: 908-913; doi:10.1093/jac/dkn018 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Christoph Wyen, Heidy Hendra, Martin Vogel, Christian Hoffmann, Heribert Knechten, Norbert H. Brockmeyer, Johannes R. Bogner, Jürgen Rockstroh, Stefan Esser, Hans Jaeger, Thomas Harrer, Stefan Mauss, Jan van Lunzen, Nicole Skoetz, Alexander Jetter, Christiane Groneuer, Gerd Fätkenheuer, Saye H. Khoo, Deirdre Egan, David J. Back, and Andrew Owen on behalf of the German Competence Network for HIV/AIDS

Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients
JAC Advance Access published on February 14, 2008
J. Antimicrob. Chemother. 2008 61: 914-918; doi:10.1093/jac/dkn029 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract D. Aguilar Marucco, D. Gonzalez de Requena, S. Bonora, C. Tettoni, M. Bonasso, T. De Blasi, A. D'Avolio, M. Sciandra, M. Siccardi, L. Baietto, L. Trentini, A. Sinicco, G. Cariti, and G. Di Perri

The use of trough ribavirin concentration to predict sustained virological response and haematological toxicity in HIV/HCV-co-infected patients treated with ribavirin and pegylated interferon
JAC Advance Access published on January 31, 2008
J. Antimicrob. Chemother. 2008 61: 919-924; doi:10.1093/jac/dkn013 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract J. A. Pineda, J. Santos, A. Rivero, L. Abdel-Kader, R. Palacios, A. Camacho, F. Lozano, and J. Macías on behalf of the Liverey Study Investigator Team

Liver toxicity of antiretroviral combinations including atazanavir/ritonavir in patients co-infected with HIV and hepatitis viruses: impact of pre-existing liver fibrosis
JAC Advance Access published on February 14, 2008
J. Antimicrob. Chemother. 2008 61: 925-932; doi:10.1093/jac/dkn045 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Hadewych J. M. ter Hofstede, Peter P. Koopmans, and David M. Burger

Stavudine plasma concentrations and lipoatrophy
JAC Advance Access published on February 14, 2008
J. Antimicrob. Chemother. 2008 61: 933-938; doi:10.1093/jac/dkn041 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Oliver A. Cornely, Angelika Böhme, Dietmar Reichert, Stefan Reuter, Georg Maschmeyer, Johan Maertens, Dieter Buchheidt, Monika Paluszewska, Dorothee Arenz, Ullrich Bethe, Jenny Effelsberg, Harry Lövenich, Michal Sieniawski, Antje Haas, Hermann Einsele, Hartmut Eimermacher, Rodrigo Martino, Gerda Silling, Moritz Hahn, Sidonie Wacker, Andrew J. Ullmann, and Meinolf Karthaus on behalf of The Multinational Case Registry of the Infectious Diseases Working Party of the German Society for Hematology and Oncology

Risk factors for breakthrough invasive fungal infection during secondary prophylaxis
JAC Advance Access published on February 12, 2008
J. Antimicrob. Chemother. 2008 61: 939-946; doi:10.1093/jac/dkn027 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Laura Hughes, Patrick Hermans, and Kenton Morgan

Risk factors for the use of prescription antibiotics on UK broiler farms
JAC Advance Access published on January 28, 2008
J. Antimicrob. Chemother. 2008 61: 947-952; doi:10.1093/jac/dkn017 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Alberto Vaccheri, Maria Chiara Silvani, Laura Bersaglia, Domenico Motola, Petar Strahinja, Antonio Vargiu, Elisabetta Poluzzi, and Nicola Montanaro

A 3 year survey on the use of antibacterial agents in five Italian hospitals
JAC Advance Access published on January 24, 2008
J. Antimicrob. Chemother. 2008 61: 953-958; doi:10.1093/jac/dkn010 [Abstract] [Full Text] [PDF] [Request Permissions]  

Research letters

Duarte C. Oliveira, Mauro Santos, Catarina Milheiriço, João A. Carriço, Susana Vinga, Arlindo L. Oliveira, and Hermínia de Lencastre

ccrB typing tool: an online resource for staphylococci ccrB sequence typing
JAC Advance Access published on January 27, 2008
J. Antimicrob. Chemother. 2008 61: 959-960; doi:10.1093/jac/dkn021 [Extract] [Full Text] [PDF] [Request Permissions]  

Patrick H. Warnke, Stephan T. Becker, Ingo N. G. Springer, Franz Härle, Uwe Ullmann, Paul A. J. Russo, Jörg Wiltfang, Helmut Fickenscher, and Sabine Schubert

‘Grandmother penicillin’—not in vogue, but clinically still effective
JAC Advance Access published on January 29, 2008
J. Antimicrob. Chemother. 2008 61: 960-962; doi:10.1093/jac/dkn030 [Extract] [Full Text] [PDF] [Request Permissions]  

Miruna D. David and Martin J. Gill

Potential for underdosing and emergence of resistance in Acinetobacter baumannii during treatment with colistin
JAC Advance Access published on January 31, 2008
J. Antimicrob. Chemother. 2008 61: 962-964; doi:10.1093/jac/dkn009 [Extract] [Full Text] [PDF] [Request Permissions]  

Letters to the Editor

Seung Ghyu Sohn, Jae Jin Lee, Eui Suk Sohn, Lin-Woo Kang, and Sang Hee Lee

Comment on: Extension of the hydrolysis spectrum of AmpC β-lactamase of Escherichia coli due to amino acid insertion in the H-10 helix
JAC Advance Access published on January 27, 2008
J. Antimicrob. Chemother. 2008 61: 965-966; doi:10.1093/jac/dkn023 [Extract] [Full Text] [PDF] [Request Permissions]  

Hedi Mammeri, Laurent Poirel, and Patrice Nordmann

Extension of the hydrolysis spectrum of AmpC β-lactamase of Escherichia coli due to amino acid insertion in the H-10 helix—authors' response
JAC Advance Access published on February 13, 2008
J. Antimicrob. Chemother. 2008 61: 966; doi:10.1093/jac/dkn064 [Extract] [Full Text] [PDF] [Request Permissions]  

Hung-Chin Tsai, Yao-Shen Chen, Susan Shin-Jung Lee, and Yung-Ching Liu

Comment on: Community-associated MRSA (CA-MRSA): an emerging pathogen in infective endocarditis
JAC Advance Access published on February 19, 2008
J. Antimicrob. Chemother. 2008 61: 966-967; doi:10.1093/jac/dkn061 [Extract] [Full Text] [PDF] [Request Permissions]  

B. Cherie Millar, Bernard D. Prendergast, and John E. Moore

Community-associated MRSA (CA-MRSA): an emerging pathogen in infective endocarditis—authors' response
JAC Advance Access published on March 5, 2008
J. Antimicrob. Chemother. 2008 61: 967-968; doi:10.1093/jac/dkn095 [Extract] [Full Text] [PDF] [Request Permissions]  

Nawal Bakkali, Florence Fenollar, Jean-Marc Rolain, and Didier Raoult

Comment on: Therapy for Whipple's disease
JAC Advance Access published on February 5, 2008
J. Antimicrob. Chemother. 2008 61: 968-969; doi:10.1093/jac/dkn035 [Extract] [Full Text] [PDF] [Request Permissions]  

Hanneke K. A. Knaapen and Pilar Barrera

Therapy for Whipple's disease—authors' response
JAC Advance Access published on March 3, 2008
J. Antimicrob. Chemother. 2008 61: 969-970; doi:10.1093/jac/dkn087 [Extract] [Full Text] [PDF] [Request Permissions]  

Erratum

Hedi Mammeri, Laurent Poirel, and Patrice Nordmann

Extension of the hydrolysis spectrum of AmpC β-lactamase of Escherichia coli due to amino acid insertion in the H-10 helix
JAC Advance Access published on February 5, 2008
J. Antimicrob. Chemother. 2008 61: 971; doi:10.1093/jac/dkn052 [Extract] [Full Text] [PDF] [Request Permissions]  

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