Journal of Antimicrobial Chemotherapy

Leading articles

Get checked abstract Pierre-Louis Toutain, Alain Bousquet-Mélou, and Marilyn Martinez

AUC/MIC: a PK/PD index for antibiotics with a time dimension or simply a dimensionless scoring factor?
JAC Advance Access published on October 11, 2007
J. Antimicrob. Chemother. 2007 60: 1185-1188; doi:10.1093/jac/dkm360 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Nicola Price and Elizabeth H. Boxall

Treatment of children persistently infected with hepatitis B virus: seroconversion or suppression
JAC Advance Access published on October 3, 2007
J. Antimicrob. Chemother. 2007 60: 1189-1192; doi:10.1093/jac/dkm362 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Meeting report

Get checked abstract Peter Davey and Jane Symonds

Meeting report: Messages from Moscow—the BSAC at the ninth IACMAC International Congress on Antimicrobial Therapy
JAC Advance Access published on October 2, 2007
J. Antimicrob. Chemother. 2007 60: 1193-1194; doi:10.1093/jac/dkm380 [Abstract] [Full Text] [PDF] [Request Permissions]  

Reviews

Get checked abstract Mike Youle

Overview of boosted protease inhibitors in treatment-experienced HIV-infected patients
JAC Advance Access published on September 21, 2007
J. Antimicrob. Chemother. 2007 60: 1195-1205; doi:10.1093/jac/dkm364 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Alexandre Prehn Zavascki, Luciano Zubaran Goldani, Jian Li, and Roger L. Nation

Polymyxin B for the treatment of multidrug-resistant pathogens: a critical review
JAC Advance Access published on September 17, 2007
J. Antimicrob. Chemother. 2007 60: 1206-1215; doi:10.1093/jac/dkm357 [Abstract] [Full Text] [PDF] [Request Permissions]  

Systematic review

Get checked abstract Eleni Ioannidou, Ilias I. Siempos, and Matthew E. Falagas

Administration of antimicrobials via the respiratory tract for the treatment of patients with nosocomial pneumonia: a meta-analysis
JAC Advance Access published on October 13, 2007
J. Antimicrob. Chemother. 2007 60: 1216-1226; doi:10.1093/jac/dkm385 [Abstract] [Full Text] [PDF] [Request Permissions]  

Original articles

Get checked abstract Noelia Martínez, M. Carmen Mendoza, Irene Rodríguez, Sara Soto, Margarita Bances, and M. Rosario Rodicio

Detailed structure of integrons and transposons carried by large conjugative plasmids responsible for multidrug resistance in diverse genomic types of Salmonella enterica serovar Brandenburg
JAC Advance Access published on September 7, 2007
J. Antimicrob. Chemother. 2007 60: 1227-1234; doi:10.1093/jac/dkm336 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Masato Akiba, Yuji Nakaoka, Muneyoshi Kida, Yukiko Ishioka, Toshiya Sameshima, Noriyo Yoshii, Muneo Nakazawa, Ikuo Uchida, and Nobuyuki Terakado

Changes in antimicrobial susceptibility in a population of Salmonella enterica serovar Dublin isolated from cattle in Japan from 1976 to 2005
JAC Advance Access published on October 23, 2007
J. Antimicrob. Chemother. 2007 60: 1235-1242; doi:10.1093/jac/dkm402 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Alexandra Moura, Isabel Henriques, Rogério Ribeiro, and António Correia

Prevalence and characterization of integrons from bacteria isolated from a slaughterhouse wastewater treatment plant
JAC Advance Access published on October 2, 2007
J. Antimicrob. Chemother. 2007 60: 1243-1250; doi:10.1093/jac/dkm340 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Marja-Liisa Hänninen and Minna Hannula

Spontaneous mutation frequency and emergence of ciprofloxacin resistance in Campylobacter jejuni and Campylobacter coli
JAC Advance Access published on October 2, 2007
J. Antimicrob. Chemother. 2007 60: 1251-1257; doi:10.1093/jac/dkm345 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Wolfgang Witte, Birgit Strommenger, Christa Cuny, Dagmar Heuck, and Ulrich Nuebel

Methicillin-resistant Staphylococcus aureus containing the Panton-Valentine leucocidin gene in Germany in 2005 and 2006
JAC Advance Access published on October 13, 2007
J. Antimicrob. Chemother. 2007 60: 1258-1263; doi:10.1093/jac/dkm384 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Hironobu Nakayama, Koichi Tanabe, Martin Bard, Wesley Hodgson, Sung Wu, Daiki Takemori, Toshihiro Aoyama, N. Selvamuthu Kumaraswami, Laurel Metzler, Yukie Takano, Hiroji Chibana, and Masakazu Niimi

The Candida glabrata putative sterol transporter gene CgAUS1 protects cells against azoles in the presence of serum
JAC Advance Access published on October 2, 2007
J. Antimicrob. Chemother. 2007 60: 1264-1272; doi:10.1093/jac/dkm321 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract L. P. Randall, S. W. Cooles, N. G. Coldham, E. G. Penuela, A. C. Mott, M. J. Woodward, L. J. V. Piddock, and M. A. Webber

Commonly used farm disinfectants can select for mutant Salmonella enterica serovar Typhimurium with decreased susceptibility to biocides and antibiotics without compromising virulence
JAC Advance Access published on September 25, 2007
J. Antimicrob. Chemother. 2007 60: 1273-1280; doi:10.1093/jac/dkm359 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Christophe Sandt, Jean Barbeau, Marc-André Gagnon, and Michel Lafleur

Role of the ammonium group in the diffusion of quaternary ammonium compounds in Streptococcus mutans biofilms
JAC Advance Access published on October 10, 2007
J. Antimicrob. Chemother. 2007 60: 1281-1287; doi:10.1093/jac/dkm382 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Lilian Pumbwe, Christopher A. Skilbeck, and Hannah M. Wexler

Induction of multiple antibiotic resistance in Bacteroides fragilis by benzene and benzene-derived active compounds of commonly used analgesics, antiseptics and cleaning agents
JAC Advance Access published on September 20, 2007
J. Antimicrob. Chemother. 2007 60: 1288-1297; doi:10.1093/jac/dkm363 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Roger Bayston, Bryar Nuradeen, Waheed Ashraf, and Brian J. C. Freeman

Antibiotics for the eradication of Propionibacterium acnes biofilms in surgical infection
JAC Advance Access published on October 24, 2007
J. Antimicrob. Chemother. 2007 60: 1298-1301; doi:10.1093/jac/dkm408 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Vincent H. Tam, Amy N. Schilling, Keith Poole, and Michael Nikolaou

Mathematical modelling response of Pseudomonas aeruginosa to meropenem
JAC Advance Access published on October 3, 2007
J. Antimicrob. Chemother. 2007 60: 1302-1309; doi:10.1093/jac/dkm370 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Michael A. Borg, Marlieke de Kraker, Elizabeth Scicluna, Nienke van de Sande-Bruinsma, Edine Tiemersma, Jos Monen, and Hajo Grundmann on behalf of the ARMed Project members and collaborators

Prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in invasive isolates from southern and eastern Mediterranean countries
JAC Advance Access published on October 2, 2007
J. Antimicrob. Chemother. 2007 60: 1310-1315; doi:10.1093/jac/dkm365 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Christopher McGuigan, Ranjith N. Pathirana, Marco Migliore, Rina Adak, Giovanna Luoni, Arwyn T. Jones, Alberto Díez-Torrubia, Maria-Jose Camarasa, Sonsoles Velázquez, Geoffrey Henson, Erik Verbeken, Rebecca Sienaert, Lieve Naesens, Robert Snoeck, Graciela Andrei, and Jan Balzarini

Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus
JAC Advance Access published on October 22, 2007
J. Antimicrob. Chemother. 2007 60: 1316-1330; doi:10.1093/jac/dkm376 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract John D. Cleary, Stanley W. Chapman, Edwin Swiatlo, and Robert Kramer

High purity amphotericin B
JAC Advance Access published on October 5, 2007
J. Antimicrob. Chemother. 2007 60: 1331-1340; doi:10.1093/jac/dkm322 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Gloria M. González, Gerardo González, Laura K. Najvar, and John R. Graybill

Therapeutic efficacy of caspofungin alone and in combination with amphotericin B deoxycholate for coccidioidomycosis in a mouse model
JAC Advance Access published on October 12, 2007
J. Antimicrob. Chemother. 2007 60: 1341-1346; doi:10.1093/jac/dkm383 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Juan A. Pineda, José A. Mira, Ignacio de los Santos Gil, Bárbara Valera-Bestard, Antonio Rivero, Dolores Merino, José A. Girón-González, María J. Ríos-Villegas, Mercedes González-Serrano, Antonio Collado, José A. García-García, Raquel Carrillo-Gómez, Luis F. López-Cortés, and Jesús Gómez-Mateos

Influence of concomitant antiretroviral therapy on the rate of sustained virological response to pegylated interferon plus ribavirin in hepatitis C virus/HIV-coinfected patients
JAC Advance Access published on October 14, 2007
J. Antimicrob. Chemother. 2007 60: 1347-1354; doi:10.1093/jac/dkm373 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Hae Suk Cheong, Cheol-In Kang, Ki Tae Kwon, Sang Tack Heo, Yu Mi Wi, Eun Seok Kim, Jin Seo Lee, Kwan Soo Ko, Doo Ryeon Chung, Nam Yong Lee, Jae-Hoon Song, and Kyong Ran Peck

Clinical significance of healthcare-associated infections in community-onset Escherichia coli bacteraemia
JAC Advance Access published on October 8, 2007
J. Antimicrob. Chemother. 2007 60: 1355-1360; doi:10.1093/jac/dkm378 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract S. Kohno, K. Yamaguchi, N. Aikawa, Y. Sumiyama, S. Odagiri, N. Aoki, Y. Niki, S. Watanabe, M. Furue, T. Ito, R. Croos-Dabrera, and K. J. Tack

Linezolid versus vancomycin for the treatment of infections caused by methicillin-resistant Staphylococcus aureus in Japan
JAC Advance Access published on October 3, 2007
J. Antimicrob. Chemother. 2007 60: 1361-1369; doi:10.1093/jac/dkm369 [Abstract] [Full Text] [PDF] [Request Permissions]  

Brief reports

Get checked abstract Elisabete Machado, Teresa M. Coque, Rafael Cantón, Ângela Novais, João Carlos Sousa, Fernando Baquero, and Luísa Peixe on behalf of The Portuguese Resistance Study Group

High diversity of extended-spectrum ß-lactamases among clinical isolates of Enterobacteriaceae from Portugal
JAC Advance Access published on October 3, 2007
J. Antimicrob. Chemother. 2007 60: 1370-1374; doi:10.1093/jac/dkm381 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract D. M. Livermore, M. Warner, and S. Mushtaq

Evaluation of the chromogenic Cica-ß-Test for detecting extended-spectrum, AmpC and metallo-ß-lactamases
JAC Advance Access published on October 3, 2007
J. Antimicrob. Chemother. 2007 60: 1375-1379; doi:10.1093/jac/dkm374 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Brian Quinn, Syed Hussain, Muhammad Malik, Karl Drlica, and Xilin Zhao

Daptomycin inoculum effects and mutant prevention concentration with Staphylococcus aureus
JAC Advance Access published on September 28, 2007
J. Antimicrob. Chemother. 2007 60: 1380-1383; doi:10.1093/jac/dkm375 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Shinya Watanabe, Teruyo Ito, and Keiichi Hiramatsu

Susceptibilities of healthcare- and community-associated methicillin-resistant staphylococci to the novel des-F(6)-quinolone DX-619
JAC Advance Access published on September 21, 2007
J. Antimicrob. Chemother. 2007 60: 1384-1387; doi:10.1093/jac/dkm361 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract H. Laue, T. Valensise, A. Seguin, S. Hawser, S. Lociuro, and K. Islam

Effect of human plasma on the antimicrobial activity of iclaprim in vitro
JAC Advance Access published on October 19, 2007
J. Antimicrob. Chemother. 2007 60: 1388-1390; doi:10.1093/jac/dkm392 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract H. Laue, L. Weiss, A. Bernardi, S. Hawser, S. Lociuro, and K. Islam

In vitro activity of the novel diaminopyrimidine, iclaprim, in combination with folate inhibitors and other antimicrobials with different mechanisms of action
JAC Advance Access published on October 25, 2007
J. Antimicrob. Chemother. 2007 60: 1391-1394; doi:10.1093/jac/dkm409 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Kazuro Ikawa, Norifumi Morikawa, Nami Urakawa, Kayo Ikeda, Hiroki Ohge, and Taijiro Sueda

Peritoneal penetration of doripenem after intravenous administration in abdominal-surgery patients
JAC Advance Access published on September 19, 2007
J. Antimicrob. Chemother. 2007 60: 1395-1397; doi:10.1093/jac/dkm371 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Helen McIlleron, Jennifer Norman, Thomas P. Kanyok, P. Bernard Fourie, John Horton, and Peter J. Smith

Elevated gatifloxacin and reduced rifampicin concentrations in a single-dose interaction study amongst healthy volunteers
JAC Advance Access published on October 20, 2007
J. Antimicrob. Chemother. 2007 60: 1398-1401; doi:10.1093/jac/dkm393 [Abstract] [Full Text] [PDF] [Request Permissions]  

Correspondence

Stijn Blot, Dominique Vandijck, Koenraad Vandewoude, Pieter Depuydt, Dirk Vogelaers, and Renaat Peleman

Comment on: Impact of antibiotic resistance and of adequate empirical antibiotic treatment in the prognosis of patients with Escherichia coli bacteraemia
JAC Advance Access published on October 3, 2007
J. Antimicrob. Chemother. 2007 60: 1402; doi:10.1093/jac/dkm379 [Extract] [Full Text] [PDF] [Request Permissions]  

Ting-ting Qu, Ya-gang Chen, Yun-song Yu, Huo-xiang Lv, Xiao-qin Dong, Zhen Xiao, Hong-qin Gu, and Lan-juan Li

Molecular characterization of vancomycin-resistant enterococci in Hangzhou, China
JAC Advance Access published on October 18, 2007
J. Antimicrob. Chemother. 2007 60: 1403-1405; doi:10.1093/jac/dkm399 [Extract] [Full Text] [PDF] [Request Permissions]  

Claudio Palmieri, Ilse-Maria Rätsch, Maria Stella Princivalli, Cinzia Candelaresi, Gloria Magi, Cinzia Spinaci, Giovanni V. Coppa, and Bruna Facinelli

erm(A)-mediated macrolide resistance and ability to invade human respiratory cells in a Streptococcus dysgalactiae subspecies equisimilis pharyngeal isolate
JAC Advance Access published on October 15, 2007
J. Antimicrob. Chemother. 2007 60: 1405-1406; doi:10.1093/jac/dkm387 [Extract] [Full Text] [PDF] [Request Permissions]  

Vasiliki Pliatsika, Zoe Afkou, Efthimia Protonotariou, and Danai Sofianou

In vitro activity of tigecycline against metallo-ß-lactamase-producing Enterobacteriaceae
JAC Advance Access published on October 25, 2007
J. Antimicrob. Chemother. 2007 60: 1406-1407; doi:10.1093/jac/dkm391 [Extract] [Full Text] [PDF] [Request Permissions]  

Yiu Wai Chu, Cindy Tse, Grand K.-L. Tsang, Daniel K.-S. So, John T.-L. Fung, and Janice Y.-C. Lo

Invasive group B Streptococcus isolates showing reduced susceptibility to penicillin in Hong Kong
JAC Advance Access published on October 24, 2007
J. Antimicrob. Chemother. 2007 60: 1407-1409; doi:10.1093/jac/dkm390 [Extract] [Full Text] [PDF] [Request Permissions]  

Eva Poveda, Carolina Garrido, Carmen de Mendoza, Angélica Corral, Julio Cobo, Juan González-Lahoz, and Vincent Soriano

Prevalence of etravirine (TMC-125) resistance mutations in HIV-infected patients with prior experience of non-nucleoside reverse transcriptase inhibitors
JAC Advance Access published on October 3, 2007
J. Antimicrob. Chemother. 2007 60: 1409-1410; doi:10.1093/jac/dkm372 [Extract] [Full Text] [PDF] [Request Permissions]  

Eva Poveda, Eugenia Vispo, Theresa Pattery, Carmen de Mendoza, Jorge Villacian, and Vincent Soriano

Impact of baseline protease genotype and phenotype on the response to darunavir outside clinical trials
JAC Advance Access published on October 2, 2007
J. Antimicrob. Chemother. 2007 60: 1411-1413; doi:10.1093/jac/dkm367 [Extract] [Full Text] [PDF] [Request Permissions]  

Elisabeth Meyer, Frank Schwab, and Petra Gastmeier

Use of very old and very new antibiotics in intensive care units in Germany
JAC Advance Access published on October 20, 2007
J. Antimicrob. Chemother. 2007 60: 1413-1415; doi:10.1093/jac/dkm394 [Extract] [Full Text] [PDF] [Request Permissions]  

Book review

Indran Balakrishnan

Antimicrobial Chemotherapy, Fifth Edition
JAC Advance Access published on October 11, 2007
J. Antimicrob. Chemother. 2007 60: 1416; doi:10.1093/jac/dkm386 [Extract] [Full Text] [PDF] [Request Permissions]  

Acknowledgement to referees

Acknowledgement to referees
J. Antimicrob. Chemother. 2007 60: 1417-1423; doi:10.1093/jac/dkm458 [Extract] [Full Text] [PDF] [Request Permissions]  

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