Journal of Antimicrobial Chemotherapy

Leading articles

Get checked abstract Robert G. Masterton and Michele Caldwell

Improving practice—the Hospital Pharmacy Initiative revisited
JAC Advance Access published on July 10, 2007
J. Antimicrob. Chemother. 2007 60: 709-711; doi:10.1093/jac/dkm250 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Jonathan Cooke, Peter Davey, Hayley Wickens, Ann Jacklin, Conor Jamieson, Ysobel Gourlay, Kieran Hand, and Sally Wellsteed

Improving practice—working together to improve the use of antimicrobials
JAC Advance Access published on August 29, 2007
J. Antimicrob. Chemother. 2007 60: 712-714; doi:10.1093/jac/dkm335 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Review

Systematic review

Get checked abstract Emanuele Nicastri, Sebastiano Leone, Claudio Angeletti, Lucia Palmisano, Loredana Sarmati, Antonio Chiesi, Andrea Geraci, Stefano Vella, Pasquale Narciso, Angela Corpolongo, and Massimo Andreoni

Sex issues in HIV-1-infected persons during highly active antiretroviral therapy: a systematic review
JAC Advance Access published on August 21, 2007
J. Antimicrob. Chemother. 2007 60: 724-732; doi:10.1093/jac/dkm302 [Abstract] [Full Text] [PDF] [Request Permissions]  

Original articles

Get checked abstract A. K. Wierzbowski, K. Nichol, N. Laing, T. Hisanaga, A. Nikulin, J. A. Karlowsky, D. J. Hoban, and G. G. Zhanel

Macrolide resistance mechanisms among Streptococcus pneumoniae isolated over 6 years of Canadian Respiratory Organism Susceptibility Study (CROSS) (1998–2004)
JAC Advance Access published on August 2, 2007
J. Antimicrob. Chemother. 2007 60: 733-740; doi:10.1093/jac/dkm273 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract F. J. U. M. van der Meer, C. A. M. de Haan, N. M. P. Schuurman, B. J. Haijema, M. H. Verheije, B. J. Bosch, J. Balzarini, and H. F. Egberink

The carbohydrate-binding plant lectins and the non-peptidic antibiotic pradimicin A target the glycans of the coronavirus envelope glycoproteins
JAC Advance Access published on August 18, 2007
J. Antimicrob. Chemother. 2007 60: 741-749; doi:10.1093/jac/dkm301 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Threes G. M. Smijs, Joke A. Bouwstra, Mojgan Talebi, and Stan Pavel

Investigation of conditions involved in the susceptibility of the dermatophyte Trichophyton rubrum to photodynamic treatment
JAC Advance Access published on August 17, 2007
J. Antimicrob. Chemother. 2007 60: 750-759; doi:10.1093/jac/dkm304 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Majed Halwani, Clement Mugabe, Ali O. Azghani, Robert M. Lafrenie, Aseem Kumar, and Abdelwahab Omri

Bactericidal efficacy of liposomal aminoglycosides against Burkholderia cenocepacia
JAC Advance Access published on August 1, 2007
J. Antimicrob. Chemother. 2007 60: 760-769; doi:10.1093/jac/dkm289 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract R. Hope, T. Parsons, S. Mushtaq, D. James, and D. M. Livermore

Determination of disc breakpoints and evaluation of Etests for tigecycline susceptibility testing by the BSAC method
JAC Advance Access published on August 18, 2007
J. Antimicrob. Chemother. 2007 60: 770-774; doi:10.1093/jac/dkm297 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Karl Pedersen, Kristina Pedersen, Helene Jensen, Kai Finster, Vibeke F. Jensen, and Ole E. Heuer

Occurrence of antimicrobial resistance in bacteria from diagnostic samples from dogs
JAC Advance Access published on July 20, 2007
J. Antimicrob. Chemother. 2007 60: 775-781; doi:10.1093/jac/dkm269 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Mi Young Lee, Kwan Soo Ko, Jae-Hoon Song, and Kyong Ran Peck

In vitro effectiveness of the antibiotic lock technique (ALT) for the treatment of catheter-related infections by Pseudomonas aeruginosa and Klebsiella pneumoniae
JAC Advance Access published on August 5, 2007
J. Antimicrob. Chemother. 2007 60: 782-787; doi:10.1093/jac/dkm295 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Gregory Steinkraus, Roger White, and Lawrence Friedrich

Vancomycin MIC creep in non-vancomycin-intermediate Staphylococcus aureus (VISA), vancomycin-susceptible clinical methicillin-resistant S. aureus (MRSA) blood isolates from 2001–05
JAC Advance Access published on July 10, 2007
J. Antimicrob. Chemother. 2007 60: 788-794; doi:10.1093/jac/dkm258 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Sara K. Olofsson, Linda L. Marcusson, Ann Strömbäck, Diarmaid Hughes, and Otto Cars

Dose-related selection of fluoroquinolone-resistant Escherichia coli
JAC Advance Access published on July 16, 2007
J. Antimicrob. Chemother. 2007 60: 795-801; doi:10.1093/jac/dkm265 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Tracy Garnier, Antti Mäntylä, Tomi Järvinen, Jayne Lawrence, Marc Brown, and Simon Croft

In vivo studies on the antileishmanial activity of buparvaquone and its prodrugs
JAC Advance Access published on August 21, 2007
J. Antimicrob. Chemother. 2007 60: 802-810; doi:10.1093/jac/dkm303 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Michael D. Edstein, Barbara M. Kotecka, Arba L. Ager, Kirsten S. Smith, Charles A. DiTusa, Damaris S. Diaz, Dennis E. Kyle, Guy A. Schiehser, David P. Jacobus, Karl H. Rieckmann, and Michael T. O'Neil

Antimalarial pharmacodynamics and pharmacokinetics of a third-generation antifolate—JPC2056—in cynomolgus monkeys using an in vivo–in vitro model
JAC Advance Access published on July 23, 2007
J. Antimicrob. Chemother. 2007 60: 811-818; doi:10.1093/jac/dkm280 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Gary E. Stein, Sharon Schooley, Charles A. Peloquin, Anne Missavage, and Daniel H. Havlichek

Linezolid tissue penetration and serum activity against strains of methicillin-resistant Staphylococcus aureus with reduced vancomycin susceptibility in diabetic patients with foot infections
JAC Advance Access published on August 1, 2007
J. Antimicrob. Chemother. 2007 60: 819-823; doi:10.1093/jac/dkm271 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract A. León, E. Martinez, M. Sarasa, Y. López, J. Mallolas, E. De Lazzari, M. Laguno, A. Milincovic, J. L. Blanco, M. Larrousse, M. Lonca, and J. M. Gatell

Impact of steady-state lopinavir plasma levels on plasma lipids and body composition after 24 weeks of lopinavir/ritonavir-containing therapy free of thymidine analogues
JAC Advance Access published on August 21, 2007
J. Antimicrob. Chemother. 2007 60: 824-830; doi:10.1093/jac/dkm285 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Elena Seminari, Anna De Bona, Gianluca Gentilini, Laura Galli, Giulia Schira, Nicola Gianotti, Caterina Uberti-Foppa, Armando Soldarini, Fernanda Dorigatti, Adriano Lazzarin, and Antonella Castagna

Amprenavir and ritonavir plasma concentrations in HIV-infected patients treated with fosamprenavir/ritonavir with various degrees of liver impairment
JAC Advance Access published on August 7, 2007
J. Antimicrob. Chemother. 2007 60: 831-836; doi:10.1093/jac/dkm282 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract I. Molina, V. Falcó, M. Crespo, C. Riera, E. Ribera, A. Curran, J. Carrio, M. Diaz, S. Villar del Saz, R. Fisa, P. López-Chejade, I. Ocaña, and A. Pahissa

Efficacy of liposomal amphotericin B for secondary prophylaxis of visceral leishmaniasis in HIV-infected patients
JAC Advance Access published on August 7, 2007
J. Antimicrob. Chemother. 2007 60: 837-842; doi:10.1093/jac/dkm294 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract A. Deplano, O. Denis, C. Nonhoff, F. Rost, B. Byl, F. Jacobs, V. Vankerckhoven, H. Goossens, and M. J. Struelens

Outbreak of hospital-adapted clonal complex-17 vancomycin-resistant Enterococcus faecium strain in a haematology unit: role of rapid typing for early control
JAC Advance Access published on July 23, 2007
J. Antimicrob. Chemother. 2007 60: 849-854; doi:10.1093/jac/dkm270 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Galo Peralta, M. Blanca Sánchez, J. Carlos Garrido, Inés De Benito, M. Eliecer Cano, Luis Martínez-Martínez, and M. Pía Roiz

Impact of antibiotic resistance and of adequate empirical antibiotic treatment in the prognosis of patients with Escherichia coli bacteraemia
JAC Advance Access published on July 20, 2007
J. Antimicrob. Chemother. 2007 60: 855-863; doi:10.1093/jac/dkm279 [Abstract] [Full Text] [PDF] [Request Permissions]  

Brief reports

Get checked abstract Mónica Blanco, Kristina Kadlec, César B. Gutiérrez Martín, Ana Judith Martín de la Fuente, Stefan Schwarz, and Jesús Navas

Nucleotide sequence and transfer properties of two novel types of Actinobacillus pleuropneumoniae plasmids carrying the tetracycline resistance gene tet(H)
JAC Advance Access published on August 17, 2007
J. Antimicrob. Chemother. 2007 60: 864-867; doi:10.1093/jac/dkm293 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Yeon-Joon Park, Jin Kyung Yu, Seungok Lee, Eun-Jee Oh, and Gun-Jo Woo

Prevalence and diversity of qnr alleles in AmpC-producing Enterobacter cloacae, Enterobacter aerogenes, Citrobacter freundii and Serratia marcescens: a multicentre study from Korea
JAC Advance Access published on July 27, 2007
J. Antimicrob. Chemother. 2007 60: 868-871; doi:10.1093/jac/dkm266 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Stéphane Corvec, Adèle Prodhomme, Cécile Giraudeau, Sandie Dauvergne, Alain Reynaud, and Nathalie Caroff

Most Escherichia coli strains overproducing chromosomal AmpC ß-lactamase belong to phylogenetic group A
JAC Advance Access published on July 27, 2007
J. Antimicrob. Chemother. 2007 60: 872-876; doi:10.1093/jac/dkm284 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Mariagrazia Perilli, Giuseppe Celenza, Marianna Fiore, Bernardetta Segatore, Cristina Pellegrini, Francesco Luzzaro, Gian Maria Rossolini, and Gianfranco Amicosante

Biochemical analysis of TEM-134, a new TEM-type extended-spectrum ß-lactamase variant produced in a Citrobacter koseri clinical isolate from an Italian hospital
JAC Advance Access published on August 2, 2007
J. Antimicrob. Chemother. 2007 60: 877-880; doi:10.1093/jac/dkm275 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Maria G. Detsika, Becky Chandler, Saye H. Khoo, Craig Winstanley, Pat Cane, David J. Back, and Andrew Owen

Detection and quantification of minority HIV isolates harbouring the D30N mutation by real-time PCR amplification
JAC Advance Access published on July 23, 2007
J. Antimicrob. Chemother. 2007 60: 881-884; doi:10.1093/jac/dkm281 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Eva Poveda, Carmen de Mendoza, Luz Martin-Carbonero, Angélica Corral, Verónica Briz, Juan González-Lahoz, and Vincent Soriano

Prevalence of darunavir resistance mutations in HIV-1-infected patients failing other protease inhibitors
JAC Advance Access published on July 23, 2007
J. Antimicrob. Chemother. 2007 60: 885-888; doi:10.1093/jac/dkm276 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Riina Rautemaa, Malcolm Richardson, Michael Pfaller, Pirkko Koukila-Kähkölä, Jaakko Perheentupa, and Harri Saxén

Decreased susceptibility of Candida albicans to azole antifungals: a complication of long-term treatment in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) patients
JAC Advance Access published on August 17, 2007
J. Antimicrob. Chemother. 2007 60: 889-892; doi:10.1093/jac/dkm299 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract E. Boselli, D. Breilh, S. Djabarouti, J. C. Bel, M. C. Saux, and B. Allaouchiche

Diffusion of ertapenem into bone and synovial tissues
JAC Advance Access published on August 17, 2007
J. Antimicrob. Chemother. 2007 60: 893-896; doi:10.1093/jac/dkm296 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract R. M. M. Cleijsen, M. E. van de Ende, F. P. Kroon, F. Verduyn Lunel, P. P. Koopmans, L. Gras, F. de Wolf, and D. M. Burger

Therapeutic drug monitoring of the HIV protease inhibitor atazanavir in clinical practice
JAC Advance Access published on August 17, 2007
J. Antimicrob. Chemother. 2007 60: 897-900; doi:10.1093/jac/dkm298 [Abstract] [Full Text] [PDF] [Request Permissions]  

Correspondence

Adrian J. Brink, Charles Feldman, and Guy A. Richards

Comment on: Best in class: a good principle for antibiotic usage to limit resistance development?
JAC Advance Access published on July 20, 2007
J. Antimicrob. Chemother. 2007 60: 901; doi:10.1093/jac/dkm278 [Extract] [Full Text] [PDF] [Request Permissions]  

Sebastian G. B. Amyes

Best in class: a good principle for antibiotic usage to limit resistance development?—author's response
JAC Advance Access published on August 30, 2007
J. Antimicrob. Chemother. 2007 60: 901-902; doi:10.1093/jac/dkm339 [Extract] [Full Text] [PDF] [Request Permissions]  

Margaret R. Hammerschlag

Comment on: Gemifloxacin once daily for 5 days versus 7 days for the treatment of community-acquired pneumonia: a randomized, multicentre, double-blind study
JAC Advance Access published on August 6, 2007
J. Antimicrob. Chemother. 2007 60: 902-903; doi:10.1093/jac/dkm290 [Extract] [Full Text] [PDF] [Request Permissions]  

T. M. File, L. A. Mandell, and G. Tillotson

Gemifloxacin once daily for 5 days versus 7 days for the treatment of community-acquired pneumonia: a randomized, multicentre, double-blind study—authors' response
JAC Advance Access published on August 30, 2007
J. Antimicrob. Chemother. 2007 60: 903; doi:10.1093/jac/dkm333 [Extract] [Full Text] [PDF] [Request Permissions]  

Corinna Kehrenberg, Katie L. Hopkins, E. John Threlfall, and Stefan Schwarz

Complete nucleotide sequence of a small qnrS1-carrying plasmid from Salmonella enterica subsp. enterica Typhimurium DT193
JAC Advance Access published on July 25, 2007
J. Antimicrob. Chemother. 2007 60: 903-905; doi:10.1093/jac/dkm283 [Extract] [Full Text] [PDF] [Request Permissions]  

Ian Morrissey and Stephen Hawser

Activity of iclaprim against Legionella pneumophila
JAC Advance Access published on August 6, 2007
J. Antimicrob. Chemother. 2007 60: 905-906; doi:10.1093/jac/dkm288 [Extract] [Full Text] [PDF] [Request Permissions]  

Arlo Upton, Jasmine Mohiuddin, Tracy Bathgate, Susan Taylor, Greg Simmons, Rosemary Woodhouse, and Helen Heffernan

High prevalence of CTX-M-15 extended-spectrum ß-lactamase among contacts of patients with shigellosis due to Shigella flexneri carrying CTX-M-15
JAC Advance Access published on July 23, 2007
J. Antimicrob. Chemother. 2007 60: 906-908; doi:10.1093/jac/dkm277 [Extract] [Full Text] [PDF] [Request Permissions]  

Josh Freeman, Amy Heshmati, David Holland, Rob Ticehurst, and Selwyn Lang

Marked increase in steady-state serum levels achieved with itraconazole oral solution compared with capsule formulation
JAC Advance Access published on July 12, 2007
J. Antimicrob. Chemother. 2007 60: 908-909; doi:10.1093/jac/dkm272 [Extract] [Full Text] [PDF] [Request Permissions]  

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