Journal of Antimicrobial Chemotherapy

Leading articles

Get checked abstract Hanneke K. A. Knaapen and Pilar Barrera

Therapy for Whipple's disease
JAC Advance Access published on July 10, 2007
J. Antimicrob. Chemother. 2007 60: 457-458; doi:10.1093/jac/dkm259 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Darius Armstrong-James

Invasive Candida species infection: the importance of adequate empirical antifungal therapy
JAC Advance Access published on July 23, 2007
J. Antimicrob. Chemother. 2007 60: 459-460; doi:10.1093/jac/dkm260 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Nicolai Lohse, Ann-Brit Eg Hansen, Jan Gerstoft, and Niels Obel

Improved survival in HIV-infected persons: consequences and perspectives
JAC Advance Access published on July 2, 2007
J. Antimicrob. Chemother. 2007 60: 461-463; doi:10.1093/jac/dkm241 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Meeting report

Get checked abstract Glenn S. Tillotson and Peter Ball

Meeting report: Fourth Forum on Respiratory Tract Infections, Sitges, Spain, 8–11 February 2007
JAC Advance Access published on June 26, 2007
J. Antimicrob. Chemother. 2007 60: 464-469; doi:10.1093/jac/dkm216 [Abstract] [Full Text] [PDF] [Request Permissions]  

Review

Get checked abstract Jan Walther-Rasmussen and Niels Høiby

Class A carbapenemases
JAC Advance Access published on June 26, 2007
J. Antimicrob. Chemother. 2007 60: 470-482; doi:10.1093/jac/dkm226 [Abstract] [Full Text] [PDF] [Request Permissions]  

Original articles

Get checked abstract Alexandr Nemec, Martina Maixnerová, Tanny J. K. van der Reijden, Peterhans J. van den Broek, and Lenie Dijkshoorn

Relationship between the AdeABC efflux system gene content, netilmicin susceptibility and multidrug resistance in a genotypically diverse collection of Acinetobacter baumannii strains
JAC Advance Access published on June 26, 2007
J. Antimicrob. Chemother. 2007 60: 483-489; doi:10.1093/jac/dkm231 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Hedi Mammeri, Laurent Poirel, and Patrice Nordmann

Extension of the hydrolysis spectrum of AmpC ß-lactamase of Escherichia coli due to amino acid insertion in the H-10 helix
JAC Advance Access published on June 22, 2007
J. Antimicrob. Chemother. 2007 60: 490-494; doi:10.1093/jac/dkm227 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Yang Wu, Kunqian Yu, Bin Xu, Lili Chen, Xianglong Chen, Jialing Mao, Antoine Danchin, Xu Shen, Di Qu, and Hualiang Jiang

Potent and selective inhibitors of Staphylococcus epidermidis tryptophanyl-tRNA synthetase
JAC Advance Access published on July 2, 2007
J. Antimicrob. Chemother. 2007 60: 502-509; doi:10.1093/jac/dkm229 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Michael P. B. Sandrini, Anders R. Clausen, Stephen L. W. On, Frank M. Aarestrup, Birgitte Munch-Petersen, and Jure Piskur

Nucleoside analogues are activated by bacterial deoxyribonucleoside kinases in a species-specific manner
JAC Advance Access published on July 5, 2007
J. Antimicrob. Chemother. 2007 60: 510-520; doi:10.1093/jac/dkm240 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract James McBride, Alexander B. Mullen, K. Christine Carter, and Craig W. Roberts

Differential cytotoxicity of phospholipid analogues to pathogenic Acanthamoeba species and mammalian cells
JAC Advance Access published on July 10, 2007
J. Antimicrob. Chemother. 2007 60: 521-525; doi:10.1093/jac/dkm245 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Danilo C. Miguel, Jenicer K. U. Yokoyama-Yasunaka, Walter K. Andreoli, Renato A. Mortara, and Silvia R. B. Uliana

Tamoxifen is effective against Leishmania and induces a rapid alkalinization of parasitophorous vacuoles harbouring Leishmania (Leishmania) amazonensis amastigotes
JAC Advance Access published on June 21, 2007
J. Antimicrob. Chemother. 2007 60: 526-534; doi:10.1093/jac/dkm219 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Robert Bucki, Audra Goach Sostarecz, Fitzroy J. Byfield, Paul B. Savage, and Paul A. Janmey

Resistance of the antibacterial agent ceragenin CSA-13 to inactivation by DNA or F-actin and its activity in cystic fibrosis sputum
JAC Advance Access published on June 21, 2007
J. Antimicrob. Chemother. 2007 60: 535-545; doi:10.1093/jac/dkm218 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Emma M. Caraher, Kiranmai Gumulapurapu, Clifford C. Taggart, Philip Murphy, Siobhán McClean, and Máire Callaghan

The effect of recombinant human lactoferrin on growth and the antibiotic susceptibility of the cystic fibrosis pathogen Burkholderia cepacia complex when cultured planktonically or as biofilms
JAC Advance Access published on June 26, 2007
J. Antimicrob. Chemother. 2007 60: 546-554; doi:10.1093/jac/dkm222 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Vicki A. Luna, Debra S. King, Jenny Gulledge, Andrew C. Cannons, Philip T. Amuso, and Jacqueline Cattani

Susceptibility of Bacillus anthracis, Bacillus cereus, Bacillus mycoides, Bacillus pseudomycoides and Bacillus thuringiensis to 24 antimicrobials using Sensititre^® automated microbroth dilution and Etest^® agar gradient diffusion methods
JAC Advance Access published on June 22, 2007
J. Antimicrob. Chemother. 2007 60: 555-567; doi:10.1093/jac/dkm213 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Hee Soo Park, Yu Min Yoon, Sung Ji Jung, Cheol Min Kim, Jeong Mi Kim, and Jin-Hwan Kwak

Antistaphylococcal activities of CG400549, a new bacterial enoyl-acyl carrier protein reductase (FabI) inhibitor
JAC Advance Access published on July 2, 2007
J. Antimicrob. Chemother. 2007 60: 568-574; doi:10.1093/jac/dkm236 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Marion Grare, Maxime Mourer, Stéphane Fontanay, Jean-Bernard Regnouf-de-Vains, Chantal Finance, and Raphaël Emmanuel Duval

In vitro activity of para-guanidinoethylcalix[4]arene against susceptible and antibiotic-resistant Gram-negative and Gram-positive bacteria
JAC Advance Access published on July 10, 2007
J. Antimicrob. Chemother. 2007 60: 575-581; doi:10.1093/jac/dkm244 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Manju Bala, Krishna Ray, S. M. Gupta, Sumathi Muralidhar, and R. K. Jain

Changing trends of antimicrobial susceptibility patterns of Neisseria gonorrhoeae in India and the emergence of ceftriaxone less susceptible N. gonorrhoeae strains
JAC Advance Access published on June 29, 2007
J. Antimicrob. Chemother. 2007 60: 582-586; doi:10.1093/jac/dkm238 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Burçin Sener, Ferda Tunçkanat, Sercan Ulusoy, Alper Tünger, Güner Söyletir, Lütfiye Mülazimoglu, Nezahat Gürler, Lütfiye Öksüz, Iftihar Köksal, Kemalettin Aydin, Ata Nevzat Yalçin, Dilara Ögünç, Asli Acar, and Jörg Sievers

A survey of antibiotic resistance in Streptococcus pneumoniae and Haemophilus influenzae in Turkey, 2004–2005
JAC Advance Access published on June 26, 2007
J. Antimicrob. Chemother. 2007 60: 587-593; doi:10.1093/jac/dkm232 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Cesar A. Arias, Kavindra V. Singh, Diana Panesso, and Barbara E. Murray

Evaluation of ceftobiprole medocaril against Enterococcus faecalis in a mouse peritonitis model
JAC Advance Access published on July 2, 2007
J. Antimicrob. Chemother. 2007 60: 594-598; doi:10.1093/jac/dkm237 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Hsin-Yun Sun, Chien-Ching Hung, Pi-Han Lin, Shu-Fang Chang, Ching-Yao Yang, Sui-Yuan Chang, and Shan-Chwen Chang

Incidence of abacavir hypersensitivity and its relationship with HLA-B*5701 in HIV-infected patients in Taiwan
JAC Advance Access published on July 12, 2007
J. Antimicrob. Chemother. 2007 60: 599-604; doi:10.1093/jac/dkm243 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Andrés Canut, Jose E. Martín-Herrero, Alicia Labora, and Hiart Maortua

What are the most appropriate antibiotics for the treatment of acute exacerbation of chronic obstructive pulmonary disease? A therapeutic outcomes model
JAC Advance Access published on June 26, 2007
J. Antimicrob. Chemother. 2007 60: 605-612; doi:10.1093/jac/dkm228 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Michael D. Parkins, Deana M. Sabuda, Sameer Elsayed, and Kevin B. Laupland

Adequacy of empirical antifungal therapy and effect on outcome among patients with invasive Candida species infections
JAC Advance Access published on June 18, 2007
J. Antimicrob. Chemother. 2007 60: 613-618; doi:10.1093/jac/dkm212 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Elisabeth Meyer, Frank Schwab, Petra Gastmeier, Henning Ruden, and Alexandra Heininger

Antifungal use in intensive care units
JAC Advance Access published on July 2, 2007
J. Antimicrob. Chemother. 2007 60: 619-624; doi:10.1093/jac/dkm255 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Jihad Bishara, Dov Hershkovitz, Mical Paul, Zvi Rotenberg, and Silvio Pitlik

Appropriateness of antibiotic therapy on weekends versus weekdays
JAC Advance Access published on June 26, 2007
J. Antimicrob. Chemother. 2007 60: 625-628; doi:10.1093/jac/dkm233 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Jina Lee, Hyunjoo Pai, Yun Kyung Kim, Nam Hee Kim, Byung Wook Eun, Hyoung Jin Kang, Kyoung Ho Park, Eun Hwa Choi, Hee Young Shin, Eui Chong Kim, Hoan Jong Lee, and Hyo Seop Ahn

Control of extended-spectrum ß-lactamase-producing Escherichia coli and Klebsiella pneumoniae in a children's hospital by changing antimicrobial agent usage policy
JAC Advance Access published on June 27, 2007
J. Antimicrob. Chemother. 2007 60: 629-637; doi:10.1093/jac/dkm225 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Attila Altiner, Silke Brockmann, Martin Sielk, Stefan Wilm, Karl Wegscheider, and Heinz-Harald Abholz

Reducing antibiotic prescriptions for acute cough by motivating GPs to change their attitudes to communication and empowering patients: a cluster-randomized intervention study
JAC Advance Access published on July 10, 2007
J. Antimicrob. Chemother. 2007 60: 638-644; doi:10.1093/jac/dkm254 [Abstract] [Full Text] [PDF] [Request Permissions]  

Brief reports

Get checked abstract Noémi Nógrády, Ákos Tóth, Ágnes Kostyák, Judit Pászti, and Béla Nagy

Emergence of multidrug-resistant clones of Salmonella Infantis in broiler chickens and humans in Hungary
JAC Advance Access published on July 6, 2007
J. Antimicrob. Chemother. 2007 60: 645-648; doi:10.1093/jac/dkm249 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Athanassios Tsakris, Satish K. Pillai, Howard S. Gold, Claudie Thauvin-Eliopoulos, Lata Venkataraman, Christine Wennersten, Robert C. Moellering, Jr, and George M. Eliopoulos

Persistence of rRNA operon mutated copies and rapid re-emergence of linezolid resistance in Staphylococcus aureus
JAC Advance Access published on July 10, 2007
J. Antimicrob. Chemother. 2007 60: 649-651; doi:10.1093/jac/dkm246 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Sarjana Jain, Jenny Andrews, Adam Fraise, and Nigel Brenwald

Rapid detection of extended-spectrum ß-lactamase-producing Gram-negative bacilli in blood cultures
JAC Advance Access published on July 12, 2007
J. Antimicrob. Chemother. 2007 60: 652-654; doi:10.1093/jac/dkm256 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Lina Marcela Aragón, Montserrat Garrigó, Carmen Moreno, Montserrat Español, and Pere Coll

Evaluation of the BacT/ALERT PZA kit in comparison with the BACTEC 460TB PZA for testing Mycobacterium tuberculosis susceptibility to pyrazinamide
JAC Advance Access published on July 5, 2007
J. Antimicrob. Chemother. 2007 60: 655-657; doi:10.1093/jac/dkm252 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Josep M. Torres-Rodríguez and Eidi Alvarado-Ramírez

In vitro susceptibilities to yeasts using the ATB^® FUNGUS 2 method, compared with Sensititre Yeast One^® and standard CLSI (NCCLS) M27-A2 methods
JAC Advance Access published on July 10, 2007
J. Antimicrob. Chemother. 2007 60: 658-661; doi:10.1093/jac/dkm247 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Inácio Mandomando, Mateu Espasa, Xavier Vallès, Jahit Sacarlal, Betuel Sigaúque, Joaquim Ruiz, and Pedro Alonso

Antimicrobial resistance of Vibrio cholerae O1 serotype Ogawa isolated in Manhiça District Hospital, southern Mozambique
JAC Advance Access published on July 11, 2007
J. Antimicrob. Chemother. 2007 60: 662-664; doi:10.1093/jac/dkm257 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Gerdien A. Tramper-Stranders, Cornelis K. van der Ent, Susan A. M. Gerritsen, André Fleer, Jan L. L. Kimpen, and Tom F. W. Wolfs

Macrolide-resistant Staphylococcus aureus colonization in cystic fibrosis patients: is there transmission to household contacts?
JAC Advance Access published on June 29, 2007
J. Antimicrob. Chemother. 2007 60: 665-668; doi:10.1093/jac/dkm235 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Berthony Deslouches, Ivan A. Gonzalez, Dilhari DeAlmeida, Kazi Islam, Chad Steele, Ronald C. Montelaro, and Timothy A. Mietzner

De novo-derived cationic antimicrobial peptide activity in a murine model of Pseudomonas aeruginosa bacteraemia
JAC Advance Access published on July 10, 2007
J. Antimicrob. Chemother. 2007 60: 669-672; doi:10.1093/jac/dkm253 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Javier Capilla, Karl V. Clemons, Raymond A. Sobel, and David A. Stevens

Efficacy of amphotericin B lipid complex in a rabbit model of coccidioidal meningitis
JAC Advance Access published on July 23, 2007
J. Antimicrob. Chemother. 2007 60: 673-676; doi:10.1093/jac/dkm264 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract J. Andrews, D. Honeybourne, J. Ashby, G. Jevons, A. Fraise, P. Fry, S. Warrington, S. Hawser, and R. Wise

Concentrations in plasma, epithelial lining fluid, alveolar macrophages and bronchial mucosa after a single intravenous dose of 1.6 mg/kg of iclaprim (AR-100) in healthy men
JAC Advance Access published on July 10, 2007
J. Antimicrob. Chemother. 2007 60: 677-680; doi:10.1093/jac/dkm242 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract David P. Nicolau, Heather K. Sun, Elyse Seltzer, Mary Buckwalter, and James A. Dowell

Pharmacokinetics of dalbavancin in plasma and skin blister fluid
JAC Advance Access published on July 12, 2007
J. Antimicrob. Chemother. 2007 60: 681-684; doi:10.1093/jac/dkm263 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Becky Chandler, Maria Detsika, Saye H. Khoo, Jill Williams, David J. Back, and Andrew Owen

Factors impacting the expression of membrane-bound proteins in lymphocytes from HIV-positive subjects
JAC Advance Access published on July 2, 2007
J. Antimicrob. Chemother. 2007 60: 685-689; doi:10.1093/jac/dkm230 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Sumit Mohan, Saud Ahmed, Behzad Alimohammadi, Manasvi Jaitly, Jen-Tse Cheng, and Velvie A. Pogue

Proteinuria lowers the risk of amphotericin B-associated hypokalaemia
JAC Advance Access published on June 27, 2007
J. Antimicrob. Chemother. 2007 60: 690-693; doi:10.1093/jac/dkm220 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Charis Marwick, Emily Watts, Josie Evans, and Peter Davey

Quality of care in sepsis management: development and testing of measures for improvement
JAC Advance Access published on June 26, 2007
J. Antimicrob. Chemother. 2007 60: 694-697; doi:10.1093/jac/dkm234 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract José Campos, Matus Ferech, Edurne Lázaro, Francisco de Abajo, Jesús Oteo, Peter Stephens, and Herman Goossens

Surveillance of outpatient antibiotic consumption in Spain according to sales data and reimbursement data
JAC Advance Access published on July 6, 2007
J. Antimicrob. Chemother. 2007 60: 698-701; doi:10.1093/jac/dkm248 [Abstract] [Full Text] [PDF] [Request Permissions]  

Correspondence

Raffaella Koncan, Aránzazu Valverde, María-Isabel Morosini, María García-Castillo, Rafael Cantón, Giuseppe Cornaglia, Fernando Baquero, and Rosa del Campo

Learning from mistakes: Taq polymerase contaminated with ß-lactamase sequences results in false emergence of Streptococcus pneumoniae containing TEM
JAC Advance Access published on June 26, 2007
J. Antimicrob. Chemother. 2007 60: 702-703; doi:10.1093/jac/dkm239 [Extract] [Full Text] [PDF] [Request Permissions]  

Amitabha Bhattacharjee, Malay Ranjan Sen, Shampa Anupurba, Pradyot Prakash, and Gopal Nath

Detection of OXA-2 group extended-spectrum-ß-lactamase-producing clinical isolates of Escherichia coli from India
JAC Advance Access published on July 10, 2007
J. Antimicrob. Chemother. 2007 60: 703-704; doi:10.1093/jac/dkm267 [Extract] [Full Text] [PDF] [Request Permissions]  

L. M. Cavaco, R. S. Hendriksen, and F. M. Aarestrup

Plasmid-mediated quinolone resistance determinant qnrS1 detected in Salmonella enterica serovar Corvallis strains isolated in Denmark and Thailand
JAC Advance Access published on July 16, 2007
J. Antimicrob. Chemother. 2007 60: 704-706; doi:10.1093/jac/dkm261 [Extract] [Full Text] [PDF] [Request Permissions]  

Chao-Yi Wu and Ping-Ing Lee

Antibiotic-lock therapy and erythromycin for treatment of catheter-related Candida parapsilosis and Staphylococcus aureus infections
JAC Advance Access published on July 10, 2007
J. Antimicrob. Chemother. 2007 60: 706-707; doi:10.1093/jac/dkm262 [Extract] [Full Text] [PDF] [Request Permissions]  

Erratum

Catarina Milheiriço, Duarte C. Oliveira, and Hermínia de Lencastre

Multiplex PCR strategy for subtyping the staphylococcal cassette chromosome mec type IV in methicillin-resistant Staphylococcus aureus: ‘SCCmec IV multiplex’
JAC Advance Access published on July 19, 2007
J. Antimicrob. Chemother. 2007 60: 708; doi:10.1093/jac/dkm268 [Extract] [Full Text] [PDF] [Request Permissions]  

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