Journal of Antimicrobial Chemotherapy

Leading articles:

A. M. EMMERSON

The need for a pneumococcal vaccine
J. Antimicrob. Chemother. 1980 6: 301-303; doi:10.1093/jac/6.3.301 [PDF] [Request Permissions]  

S. G. B. AMYES

Boston: mechanisms of antimicrobial drug resistance
J. Antimicrob. Chemother. 1980 6: 303-305; doi:10.1093/jac/6.3.303 [PDF] [Request Permissions]  

C. J. ELLIS

How should we use metronidazole?
J. Antimicrob. Chemother. 1980 6: 305-307; doi:10.1093/jac/6.3.305 [PDF] [Request Permissions]  

J. L. MADDOCKS

Indirect pathogenicity
J. Antimicrob. Chemother. 1980 6: 307-309; doi:10.1093/jac/6.3.307 [PDF] [Request Permissions]  

Review article:

G. N. Rolinson

The significance of protein binding of antibiotics in antibacterial chemotherapy
J. Antimicrob. Chemother. 1980 6: 311-317; doi:10.1093/jac/6.3.311 [PDF] [Request Permissions]  

Original articles:

R. Wise, S. Baker, N. Wright, and R. Livingston

The pharmacokinetics of LY127935, a broad spectrum oxa-ß-lactam
J. Antimicrob. Chemother. 1980 6: 319-322; doi:10.1093/jac/6.3.319 [Abstract] [PDF] [Request Permissions]  

Richard F. Collins and Larry D. Edwards

In vitro synergy of cefazolin-tobramycin against Gram-positive bacteria
J. Antimicrob. Chemother. 1980 6: 323-331; doi:10.1093/jac/6.3.323 [Abstract] [PDF] [Request Permissions]  

M. J. Basker, R. A. Edmondson, and R. Sutherland

Comparative stabilities of penicillins and cephalosporins to staphylococcal ß-lactamase and activities against Staphylococcus aureus
J. Antimicrob. Chemother. 1980 6: 333-341; doi:10.1093/jac/6.3.333 [Abstract] [PDF] [Request Permissions]  

H. R. Ingham, C. J. Hall, Penelope R. Sisson, Danka Tharagonnet, and J. B. Selkon

The activity of metronidazole against facultatively anaerobic bacteria
J. Antimicrob. Chemother. 1980 6: 343-347; doi:10.1093/jac/6.3.343 [Abstract] [PDF] [Request Permissions]  

R. N. Grüneberg and A. M. Emmerson

Prevention of emergence of bacterial resistance by combination of two antibiotics: rifampicin and trimethoprim
J. Antimicrob. Chemother. 1980 6: 349-356; doi:10.1093/jac/6.3.349 [Abstract] [PDF] [Request Permissions]  

Teresa Urban and Connie Jarstrand

Rapid micromethod for aminoglycoside assays in serum by utilization of bacterial reduction of nitroblue tetrazolium
J. Antimicrob. Chemother. 1980 6: 357-361; doi:10.1093/jac/6.3.357 [Abstract] [PDF] [Request Permissions]  

Larry J. Strausbaugh, Thomas W. Murray, and Merle A. Sande

Comparative penetration of six antibiotics into the cerebrospinal fluid of rabbits with experimental staphylococcal meningitis
J. Antimicrob. Chemother. 1980 6: 363-371; doi:10.1093/jac/6.3.363 [Abstract] [PDF] [Request Permissions]  

P. G. Welling, M. J. Kendall, S. Dean, R. Wise, and J. M. Andrews

Effect of food on the bioavailability of alafosfalin, a new antibacterial agent
J. Antimicrob. Chemother. 1980 6: 373-379; doi:10.1093/jac/6.3.373 [Abstract] [PDF] [Request Permissions]  

C. Baylis

The mechanism of the decline in glomerular filtration rate in gentamicin-induced acute renal failure in the rat
J. Antimicrob. Chemother. 1980 6: 381-388; doi:10.1093/jac/6.3.381 [Abstract] [PDF] [Request Permissions]  

C. W. Clarke, C. S. May, W. Robinson, P. Hampshire, and B. D. Rawal

A new formulation of erythromycin stearate: blood and sputum levels in patients with chronic lower respiratory tract infection
J. Antimicrob. Chemother. 1980 6: 389-392; doi:10.1093/jac/6.3.389 [Abstract] [PDF] [Request Permissions]  

N. J. Mitchell, D. S. Evans, and D. Pollock

Pre-operation single-dose cefuroxime antimicrobial prophylaxis with and without metronidazole in elective gastrointestinal surgery
J. Antimicrob. Chemother. 1980 6: 393-399; doi:10.1093/jac/6.3.393 [Abstract] [PDF] [Request Permissions]  

Correspondence:

S. SELWYN

Comparison and classification of cephalosporins
J. Antimicrob. Chemother. 1980 6: 401-402; doi:10.1093/jac/6.3.401 [PDF] [Request Permissions]  

D. I. EDWARDS and D. SHANSON

Metronidazole inactivation by aerobes
J. Antimicrob. Chemother. 1980 6: 402-403; doi:10.1093/jac/6.3.402 [PDF] [Request Permissions]  

D. A. LEIGH, J. MARRINER, and S. FABB

Treatment of domiciliary urinary tract infections with a single dose of amoxycillin
J. Antimicrob. Chemother. 1980 6: 403-405; doi:10.1093/jac/6.3.403 [PDF] [Request Permissions]  

B. TROLLFORS and R. NORRBY

Effect of frusemide on the elimination of cefuroxime and cefoxitin
J. Antimicrob. Chemother. 1980 6: 405-407; doi:10.1093/jac/6.3.405 [PDF] [Request Permissions]  

P. ACRED, P. GRUJIC, D. M. RYAN, L. XERRI, P. ORSOLINI, and E. ERANI

In vitro activity of cefuroxime against Treponema pallidum and Neisseria gonorrhoeae
J. Antimicrob. Chemother. 1980 6: 407-408; doi:10.1093/jac/6.3.407 [PDF] [Request Permissions]  

OTTO CARS and SÖREN ÖGREN

Tissue penetration of ampicillin: parallel determinations of levels in tissue cage fluid and rabbit muscle
J. Antimicrob. Chemother. 1980 6: 408-409; doi:10.1093/jac/6.3.408 [PDF] [Request Permissions]  

R. HONE and M. FOLEY

In vitro activity of mecillinam and mecillinam/ampicillin combinations on Proteus species
J. Antimicrob. Chemother. 1980 6: 410-412; doi:10.1093/jac/6.3.410 [PDF] [Request Permissions]  

RONICA M. KLUGE

Comparative in vitro activity of methicillin, oxacillin and cefamandole against clinical isolates of Staphylococcus aureus
J. Antimicrob. Chemother. 1980 6: 412-415; doi:10.1093/jac/6.3.412 [PDF] [Request Permissions]  

F. DASCHNER and S. NOPPER

Susceptibility of nosocomial Acinetobacter anitratus strains to 14 antibiotics
J. Antimicrob. Chemother. 1980 6: 415-416; doi:10.1093/jac/6.3.415 [PDF] [Request Permissions]  

J. R. NEEDHAM, J. E. COOPER, and G. D. ZANELLI

Investigation of serum carbenicillin levels in healthy greyhounds and beagles
J. Antimicrob. Chemother. 1980 6: 416-418; doi:10.1093/jac/6.3.416 [PDF] [Request Permissions]  

B. CHATTOPADHYAY and J. C. TELI

In vitro activity of mezlocillin against Enterobacteriaceae
J. Antimicrob. Chemother. 1980 6: 418-420; doi:10.1093/jac/6.3.418 [PDF] [Request Permissions]  

SHIGERU YAMABE

Spectrophotometric determination of inhibitory effects of CP-45899 on ß-lactamase with benzylpenicillin and nitrocefin
J. Antimicrob. Chemother. 1980 6: 420-421; doi:10.1093/jac/6.3.420 [PDF] [Request Permissions]  

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