Journal of Antimicrobial Chemotherapy

Leading articles

Get checked abstract Ian Chopra

The increasing use of silver-based products as antimicrobial agents: a useful development or a cause for concern?
JAC Advance Access published on February 16, 2007
J. Antimicrob. Chemother. 2007 59: 587-590; doi:10.1093/jac/dkm006 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Andrew Lucas, David Nolan, and Simon Mallal

HLA-B*5701 screening for susceptibility to abacavir hypersensitivity
JAC Advance Access published on February 22, 2007
J. Antimicrob. Chemother. 2007 59: 591-593; doi:10.1093/jac/dkl557 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles

Get checked abstract An T. T. Vo, Engeline van Duijkeren, Ad C. Fluit, and Wim Gaastra

A novel Salmonella genomic island 1 and rare integron types in Salmonella Typhimurium isolates from horses in The Netherlands
JAC Advance Access published on February 9, 2007
J. Antimicrob. Chemother. 2007 59: 594-599; doi:10.1093/jac/dkl531 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract P. Lüthje, M. von Köckritz-Blickwede, and S. Schwarz

Identification and characterization of nine novel types of small staphylococcal plasmids carrying the lincosamide nucleotidyltransferase gene lnu(A)
JAC Advance Access published on February 28, 2007
J. Antimicrob. Chemother. 2007 59: 600-606; doi:10.1093/jac/dkm008 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract A. Bizzini, J. M. Entenza, and P. Moreillon

Loss of penicillin tolerance by inactivating the carbon catabolite repression determinant CcpA in Streptococcus gordonii
JAC Advance Access published on February 27, 2007
J. Antimicrob. Chemother. 2007 59: 607-615; doi:10.1093/jac/dkm021 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract P. David Rogers, Teresa T. Liu, Katherine S. Barker, George M. Hilliard, B. Keith English, Justin Thornton, Edwin Swiatlo, and Larry S. McDaniel

Gene expression profiling of the response of Streptococcus pneumoniae to penicillin
JAC Advance Access published on March 5, 2007
J. Antimicrob. Chemother. 2007 59: 616-626; doi:10.1093/jac/dkl560 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Tse Hsien Koh, Li-Hwei Sng, Grace Chee Yeng Wang, Li-Yang Hsu, and Yi Zhao

IMP-4 and OXA ß-lactamases in Acinetobacter baumannii from Singapore
JAC Advance Access published on February 6, 2007
J. Antimicrob. Chemother. 2007 59: 627-632; doi:10.1093/jac/dkl544 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Jung Hoon Lee, Chul Hee Choi, Hee Young Kang, Ji Young Lee, Jungmin Kim, Yoo Chul Lee, Sung Yong Seol, Dong Taek Cho, Kun Woo Kim, Do Young Song, and Je Chul Lee

Differences in phenotypic and genotypic traits against antimicrobial agents between Acinetobacter baumannii and Acinetobacter genomic species 13TU
JAC Advance Access published on March 5, 2007
J. Antimicrob. Chemother. 2007 59: 633-639; doi:10.1093/jac/dkm007 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract M.-F. Odou, C. Muller, L. Calvet, and L. Dubreuil

In vitro activity against anaerobes of retapamulin, a new topical antibiotic for treatment of skin infections
JAC Advance Access published on March 9, 2007
J. Antimicrob. Chemother. 2007 59: 646-651; doi:10.1093/jac/dkm019 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract L. Alou, M. J. Giménez, D. Sevillano, L. Aguilar, N. González, O. Echeverría, M. Torrico, P. Coronel, and J. Prieto

Are ß-lactam breakpoints adequate to define non-susceptibility for all Haemophilus influenzae resistance phenotypes from a pharmacodynamic point of view?
JAC Advance Access published on March 6, 2007
J. Antimicrob. Chemother. 2007 59: 652-657; doi:10.1093/jac/dkm015 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract L. Vivas, L. Rattray, L. B. Stewart, B. L. Robinson, B. Fugmann, R. K. Haynes, W. Peters, and S. L. Croft

Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo
JAC Advance Access published on March 2, 2007
J. Antimicrob. Chemother. 2007 59: 658-665; doi:10.1093/jac/dkl563 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract Luigia Rossi, Palmarisa Franchetti, Francesca Pierigé, Loredana Cappellacci, Sonja Serafini, Emanuela Balestra, Carlo-Federico Perno, Mario Grifantini, Raffaele Caliò, and Mauro Magnani

Inhibition of HIV-1 replication in macrophages by a heterodinucleotide of lamivudine and tenofovir
JAC Advance Access published on February 27, 2007
J. Antimicrob. Chemother. 2007 59: 666-675; doi:10.1093/jac/dkm011 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Fabian E. Lopez, Paula A. Vincent, Ana M. Zenoff, Raúl A. Salomón, and Ricardo N. Farías

Efficacy of microcin J25 in biomatrices and in a mouse model of Salmonella infection
JAC Advance Access published on March 12, 2007
J. Antimicrob. Chemother. 2007 59: 676-680; doi:10.1093/jac/dkm009 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Esteban Ribera, Carlos Azuaje, Rosa M. Lopez, Pere Domingo, Adria Curran, Maria Feijoo, Leonor Pou, Paquita Sánchez, Maria Antonia Sambeat, Joan Colomer, Josep Lluis Lopez-Colomes, Manuel Crespo, Vicenç Falcó, Imma Ocaña, and Albert Pahissa

Pharmacokinetic interaction between rifampicin and the once-daily combination of saquinavir and low-dose ritonavir in HIV-infected patients with tuberculosis
JAC Advance Access published on February 16, 2007
J. Antimicrob. Chemother. 2007 59: 690-697; doi:10.1093/jac/dkl552 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Carmen de Mendoza, Carmen Rodriguez, Federico García, José M. Eiros, Lidia Ruíz, Estrella Caballero, Antonio Aguilera, Pilar Leiva, Javier Colomina, Felix Gutierrez, Jorge del Romero, Jesús Aguero, and Vincent Soriano on behalf of the Spanish HIV Seroconverter Study Group

Prevalence of X4 tropic viruses in patients recently infected with HIV-1 and lack of association with transmission of drug resistance
JAC Advance Access published on February 27, 2007
J. Antimicrob. Chemother. 2007 59: 698-704; doi:10.1093/jac/dkm012 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Daniel M. Musher, Nancy Logan, Vaibhav Mehendiratta, Nicolas A. Melgarejo, Sagar Garud, and Richard J. Hamill

Clostridium difficile colitis that fails conventional metronidazole therapy: response to nitazoxanide
JAC Advance Access published on March 2, 2007
J. Antimicrob. Chemother. 2007 59: 705-710; doi:10.1093/jac/dkl553 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Dag Torfoss, E. Arne Høiby, Jon Magnus Tangen, Harald Holte, Kåre Bø, Peter Meyer, Kjell Grøttum, Kjetil Weyde, Grete Fossum Lauritzsen, Berit Sandstad, Anne-Birgitte Jacobsen, Harald Olsen, and Stein Kvaløy

Tobramycin once versus three times daily, given with penicillin G, to febrile neutropenic cancer patients in Norway: a prospective, randomized, multicentre trial
JAC Advance Access published on February 27, 2007
J. Antimicrob. Chemother. 2007 59: 711-717; doi:10.1093/jac/dkm003 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Get checked abstract N. Nyazema, N. Viberg, S. Khoza, S. Vyas, L. Kumaranayake, G. Tomson, and C. Stålsby Lundborg

Low sale of antibiotics without prescription: a cross-sectional study in Zimbabwean private pharmacies
JAC Advance Access published on March 2, 2007
J. Antimicrob. Chemother. 2007 59: 718-726; doi:10.1093/jac/dkm013 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Cliodna A. M. McNulty, Paul Boyle, Tom Nichols, Peter Clappison, and Peter Davey

Don't wear me out—the public's knowledge of and attitudes to antibiotic use
JAC Advance Access published on February 16, 2007
J. Antimicrob. Chemother. 2007 59: 727-738; doi:10.1093/jac/dkl558 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Brief reports

Get checked abstract Athanassios Tsakris, Alexandros Ikonomidis, Nicholas Spanakis, Aggeliki Poulou, and Spyros Pournaras

Characterization of In3Mor, a new integron carrying VIM-1 metallo-ß-lactamase and sat1 gene, from Morganella morganii
JAC Advance Access published on March 6, 2007
J. Antimicrob. Chemother. 2007 59: 739-741; doi:10.1093/jac/dkm020 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Thierry Frank, Valérie Gautier, Antoine Talarmin, Raymond Bercion, and Guillaume Arlet

Characterization of sulphonamide resistance genes and class 1 integron gene cassettes in Enterobacteriaceae, Central African Republic (CAR)
JAC Advance Access published on March 9, 2007
J. Antimicrob. Chemother. 2007 59: 742-745; doi:10.1093/jac/dkl538 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Alieda van Essen-Zandbergen, Hilde Smith, Kees Veldman, and Dik Mevius

Occurrence and characteristics of class 1, 2 and 3 integrons in Escherichia coli, Salmonella and Campylobacter spp. in the Netherlands
JAC Advance Access published on February 16, 2007
J. Antimicrob. Chemother. 2007 59: 746-750; doi:10.1093/jac/dkl549 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Vincent Cattoir, François-Xavier Weill, Laurent Poirel, Laëtitia Fabre, Claude-James Soussy, and Patrice Nordmann

Prevalence of qnr genes in Salmonella in France
JAC Advance Access published on February 16, 2007
J. Antimicrob. Chemother. 2007 59: 751-754; doi:10.1093/jac/dkl547 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Hoang Anh Nguyen, Jean Grellet, Véronique Dubois, Marie-Claude Saux, and Claudine Quentin

Factors compromising the activity of moxifloxacin against intracellular Staphylococcus aureus
JAC Advance Access published on March 12, 2007
J. Antimicrob. Chemother. 2007 59: 755-758; doi:10.1093/jac/dkm004 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Shirley Graham and Peter J. Coote

Potent, synergistic inhibition of Staphylococcus aureus upon exposure to a combination of the endopeptidase lysostaphin and the cationic peptide ranalexin
JAC Advance Access published on February 26, 2007
J. Antimicrob. Chemother. 2007 59: 759-762; doi:10.1093/jac/dkl539 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Olivier F. Join-Lambert, Sylvain Clauser, Christelle Guillet, Jean-Philippe Jais, Eric Abachin, Gilles Quesnes, Etienne Carbonnelle, Alban Le Monnier, Jean-Ralph Zahar, Samer Kayal, Patrick Berche, and Agnès Ferroni

Comparison of cefoxitin and moxalactam 30 µg disc diffusion methods for detection of methicillin resistance in coagulase-negative staphylococci
JAC Advance Access published on March 5, 2007
J. Antimicrob. Chemother. 2007 59: 763-766; doi:10.1093/jac/dkl548 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Ralf Fleck, Annebärbel Dietz, and Herbert Hof

In vitro susceptibility of Candida species to five antifungal agents in a German university hospital assessed by the reference broth microdilution method and Etest
JAC Advance Access published on February 9, 2007
J. Antimicrob. Chemother. 2007 59: 767-771; doi:10.1093/jac/dkl555 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Shiri Navon-Venezia, Azita Leavitt, and Yehuda Carmeli

High tigecycline resistance in multidrug-resistant Acinetobacter baumannii
JAC Advance Access published on March 12, 2007
J. Antimicrob. Chemother. 2007 59: 772-774; doi:10.1093/jac/dkm018 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Jeanette K. Miflin, Jillian M. Templeton, and P. J. Blackall

Antibiotic resistance in Campylobacter jejuni and Campylobacter coli isolated from poultry in the South-East Queensland region
J. Antimicrob. Chemother. 2007 59: 775-778; doi:10.1093/jac/dkm024 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Stephen T. Chambers, Alan Pithie, Katrina Gallagher, Tina Liu, Christopher J. Charles, and Lois Seaward

Treatment of Staphylococcus epidermidis central vascular catheter infection with 70% ethanol locks: efficacy in a sheep model
JAC Advance Access published on February 5, 2007
J. Antimicrob. Chemother. 2007 59: 779-782; doi:10.1093/jac/dkl542 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Vincenzo De Francesco, Marcella Margiotta, Angelo Zullo, Cesare Hassan, Floriana Giorgio, Osvaldo Burattini, Giuseppe Stoppino, Ugo Cea, Antonella Pace, Mariangela Zotti, Sergio Morini, Carmine Panella, and Enzo Ierardi

Prevalence of primary clarithromycin resistance in Helicobacter pylori strains over a 15 year period in Italy
JAC Advance Access published on February 28, 2007
J. Antimicrob. Chemother. 2007 59: 783-785; doi:10.1093/jac/dkm005 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Anastasia Antoniadou, Flora Kontopidou, Garifalia Poulakou, Evangelos Koratzanis, Irene Galani, Evangelos Papadomichelakis, Petros Kopterides, Maria Souli, Apostolos Armaganidis, and Helen Giamarellou

Colistin-resistant isolates of Klebsiella pneumoniae emerging in intensive care unit patients: first report of a multiclonal cluster
JAC Advance Access published on February 16, 2007
J. Antimicrob. Chemother. 2007 59: 786-790; doi:10.1093/jac/dkl562 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract A. C. Pasqualotto, S. J. Howard, C. B. Moore, and D. W. Denning

Flucytosine therapeutic monitoring: 15 years experience from the UK
JAC Advance Access published on March 5, 2007
J. Antimicrob. Chemother. 2007 59: 791-793; doi:10.1093/jac/dkl550 [Abstract] [Full Text] [PDF] [Request Permissions]  

Get checked abstract Jesús Fortún, Pilar Martín-Dávila, Auxiliadora Molina, Enrique Navas, José Manuel Hermida, Javier Cobo, Enrique Gómez-Mampaso, and Santiago Moreno

Sputum conversion among patients with pulmonary tuberculosis: are there implications for removal of respiratory isolation?
J. Antimicrob. Chemother. 2007 59: 794-798; doi:10.1093/jac/dkm025 [Abstract] [Full Text] [PDF] [Request Permissions]  

Correspondence

T. R. Walsh, M. A. Toleman, and R. N. Jones

Comment on: Occurrence, prevalence and genetic environment of CTX-M ß-lactamases in Enterobacteriaceae from Indian hospitals
JAC Advance Access published on February 8, 2007
J. Antimicrob. Chemother. 2007 59: 799-800; doi:10.1093/jac/dkl532 [Extract] [Full Text] [PDF] [Request Permissions]  

V. M. Ensor, M. Shahid, J. T. Evans, and P. M. Hawkey

Occurrence, prevalence and genetic environment of CTX-M ß-lactamases in Enterobacteriaceae from Indian hospitals—authors' response
JAC Advance Access published on March 9, 2007
J. Antimicrob. Chemother. 2007 59: 800; doi:10.1093/jac/dkm017 [Extract] [Full Text] [PDF] [Request Permissions]  

Benoît Doublet, George R. Golding, Michael R. Mulvey, and Axel Cloeckaert

Potential integration sites of the Salmonella genomic island 1 in Proteus mirabilis and other bacteria
JAC Advance Access published on February 9, 2007
J. Antimicrob. Chemother. 2007 59: 801-803; doi:10.1093/jac/dkl540 [Extract] [Full Text] [PDF] [Request Permissions]  

Rina Karunakaran and I-Ching Sam

Mutations in gyrA and parC in ciprofloxacin-resistant Neisseria gonorrhoeae in Kuala Lumpur, Malaysia
JAC Advance Access published on February 28, 2007
J. Antimicrob. Chemother. 2007 59: 803-804; doi:10.1093/jac/dkm016 [Extract] [Full Text] [PDF] [Request Permissions]  

L. M. Cavaco, D. S. Hansen, A. Friis-Møller, F. M. Aarestrup, H. Hasman, and N. Frimodt-Møller

First detection of plasmid-mediated quinolone resistance (qnrA and qnrS) in Escherichia coli strains isolated from humans in Scandinavia
JAC Advance Access published on February 6, 2007
J. Antimicrob. Chemother. 2007 59: 804-805; doi:10.1093/jac/dkl554 [Extract] [Full Text] [PDF] [Request Permissions]  

Teresa Nebreda, Jesús Oteo, Carmen Aldea, Carmen García-Estébanez, Juan Gastelu-Iturri, Verónica Bautista, Silvia García-Cobos, and José Campos

Hospital dissemination of a clonal complex 17 vanB2-containing Enterococcus faecium
JAC Advance Access published on February 28, 2007
J. Antimicrob. Chemother. 2007 59: 806-807; doi:10.1093/jac/dkm022 [Extract] [Full Text] [PDF] [Request Permissions]  

B. Ni Laoi, C. Herra, S. Norris, and B. Crowley

Hepatitis B virus resistance to adefovir in a nucleotide naive patient with chronic hepatitis B virus infection
JAC Advance Access published on March 1, 2007
J. Antimicrob. Chemother. 2007 59: 807-809; doi:10.1093/jac/dkm026 [Extract] [Full Text] [PDF] [Request Permissions]  

H. L. Young, S. A. Ballard, P. Roffey, and M. L. Grayson

Direct detection of vanB2 using the Roche LightCycler vanA/B detection assay to indicate vancomycin-resistant enterococcal carriage – sensitive but not specific
JAC Advance Access published on February 6, 2007
J. Antimicrob. Chemother. 2007 59: 809-810; doi:10.1093/jac/dkl543 [Extract] [Full Text] [PDF] [Request Permissions]  

Lorena López-Cerero, Marina de Cueto, Miguel Angel Díaz-Guerrero, Concepción Morillo, and Alvaro Pascual

Evaluation of the Etest method for fosfomycin susceptibility of ESBL-producing Klebsiella pneumoniae
JAC Advance Access published on February 8, 2007
J. Antimicrob. Chemother. 2007 59: 810-812; doi:10.1093/jac/dkl545 [Extract] [Full Text] [PDF] [Request Permissions]  

L. Bergès, H. Rodriguez-Villalobos, A. Deplano, and M. J. Struelens

Prospective evaluation of imipenem/EDTA combined disc and Etest for detection of metallo-ß-lactamase-producing Pseudomonas aeruginosa
JAC Advance Access published on February 22, 2007
J. Antimicrob. Chemother. 2007 59: 812-813; doi:10.1093/jac/dkm001 [Extract] [Full Text] [PDF] [Request Permissions]  

Line Bagger-Skjøt, Eva M. Nielsen, Dorthe Sandvang, Steen Ethelberg, Dominique L. Monnet, and Anette M. Hammerum

Less frequent Salmonella serovars as a reservoir of antimicrobial resistance
JAC Advance Access published on March 6, 2007
J. Antimicrob. Chemother. 2007 59: 814-815; doi:10.1093/jac/dkm010 [Extract] [Full Text] [PDF] [Request Permissions]  

F. Tarrant, A. P. MacGowan, and T. R. Walsh

Occurrence and current frequency of CTX-M-type ß-lactamases from a regional hospital in the South West of England
JAC Advance Access published on February 8, 2007
J. Antimicrob. Chemother. 2007 59: 815-816; doi:10.1093/jac/dkl559 [Extract] [Full Text] [PDF] [Request Permissions]  

Jon Iredell, Lee Thomas, Damla Power, and Eulogio Mendes

Tigecycline resistance in Australian antibiotic-resistant Gram-negative bacteria
JAC Advance Access published on March 12, 2007
J. Antimicrob. Chemother. 2007 59: 816-818; doi:10.1093/jac/dkm002 [Extract] [Full Text] [PDF] [Request Permissions]  

E. Denes, A. Boumediene, H. Durox, A. Oksman, F. Saint-Marcoux, M.-L. Darde, and J.-M. Gaulier

Voriconazole concentrations in synovial fluid and bone tissues
JAC Advance Access published on February 28, 2007
J. Antimicrob. Chemother. 2007 59: 818-819; doi:10.1093/jac/dkm023 [Extract] [Full Text] [PDF] [Request Permissions]  

Charis A. Marwick and Dilip Nathwani

Improving antimicrobial prescribing through knowledge and skills
JAC Advance Access published on February 5, 2007
J. Antimicrob. Chemother. 2007 59: 819-820; doi:10.1093/jac/dkl546 [Extract] [Full Text] [PDF] [Request Permissions]  

Erratum

R. S. Braithwaite, S. Shechter, M. S. Roberts, A. Schaefer, D. R. Bangsberg, P. R. Harrigan, and A. C. Justice

Explaining variability in the relationship between antiretroviral adherence and HIV mutation accumulation
JAC Advance Access published on March 6, 2007
J. Antimicrob. Chemother. 2007 59: 821; doi:10.1093/jac/dkm027 [Extract] [Full Text] [PDF] [Request Permissions]  

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