Journal of Antimicrobial Chemotherapy

Leading articles

Get checked abstract Jane Democratis, Manish Pareek, and Iain Stephenson

Use of neuraminidase inhibitors to combat pandemic influenza
JAC Advance Access published on September 6, 2006
J. Antimicrob. Chemother. 2006 58: 911-915; doi:10.1093/jac/dkl376 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Review

Get checked abstract A. C. Rodloff, E. J. C. Goldstein, and A. Torres

Two decades of imipenem therapy
JAC Advance Access published on September 22, 2006
J. Antimicrob. Chemother. 2006 58: 916-929; doi:10.1093/jac/dkl354 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles

Get checked abstract P. Barco, R. F. Cardoso, R. D. C. Hirata, C. Q. F. Leite, J. R. Pandolfi, D. N. Sato, M. L. Shikama, F. Fiúza de Melo, E. M. Mamizuka, P. A. Z. Campanerut, and M. H. Hirata

pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis clinical isolates from the southeast region of Brazil
JAC Advance Access published on September 13, 2006
J. Antimicrob. Chemother. 2006 58: 930-935; doi:10.1093/jac/dkl363 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Mary Margaret Wade and Ying Zhang

Effects of weak acids, UV and proton motive force inhibitors on pyrazinamide activity against Mycobacterium tuberculosis in vitro
JAC Advance Access published on September 1, 2006
J. Antimicrob. Chemother. 2006 58: 936-941; doi:10.1093/jac/dkl358 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Kelly Ishida, João Carlos Palazzo de Mello, Diógenes Aparício Garcia Cortez, Benedito Prado Dias Filho, Tânia Ueda-Nakamura, and Celso Vataru Nakamura

Influence of tannins from Stryphnodendron adstringens on growth and virulence factors of Candida albicans
JAC Advance Access published on September 14, 2006
J. Antimicrob. Chemother. 2006 58: 942-949; doi:10.1093/jac/dkl377 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Monica Benincasa, Marco Scocchi, Sabrina Pacor, Alessandro Tossi, Donatella Nobili, Giancarlo Basaglia, Marina Busetti, and Renato Gennaro

Fungicidal activity of five cathelicidin peptides against clinically isolated yeasts
JAC Advance Access published on October 5, 2006
J. Antimicrob. Chemother. 2006 58: 950-959; doi:10.1093/jac/dkl382 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Inga Odenholt and Otto Cars

Pharmacodynamics of moxifloxacin and levofloxacin against Streptococcus pneumoniae, Staphylococcus aureus, Klebsiella pneumoniae and Escherichia coli: simulation of human plasma concentrations after intravenous dosage in an in vitro kinetic model
JAC Advance Access published on August 26, 2006
J. Antimicrob. Chemother. 2006 58: 960-965; doi:10.1093/jac/dkl356 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Jun Lin and Ad'Lynn Martinez

Effect of efflux pump inhibitors on bile resistance and in vivo colonization of Campylobacter jejuni
JAC Advance Access published on September 7, 2006
J. Antimicrob. Chemother. 2006 58: 966-972; doi:10.1093/jac/dkl374 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Brad Spellberg, Julie Schwartz, Yue Fu, Valentina Avanesian, Jill Adler-Moore, John E. Edwards, Jr, and Ashraf S. Ibrahim

Comparison of antifungal treatments for murine fusariosis
JAC Advance Access published on September 14, 2006
J. Antimicrob. Chemother. 2006 58: 973-979; doi:10.1093/jac/dkl378 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Juliana F. Roos, Jurgen Bulitta, Jeffrey Lipman, and Carl M. J. Kirkpatrick

Pharmacokinetic-pharmacodynamic rationale for cefepime dosing regimens in intensive care units
JAC Advance Access published on August 30, 2006
J. Antimicrob. Chemother. 2006 58: 987-993; doi:10.1093/jac/dkl349 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Rainer Wacke, Sven Förster, Ulrich Adam, Ralf G. Mundkowski, Ernst Klar, Ulrich T. Hopt, and Bernd Drewelow

Penetration of moxifloxacin into the human pancreas following a single intravenous or oral dose
JAC Advance Access published on September 6, 2006
J. Antimicrob. Chemother. 2006 58: 994-999; doi:10.1093/jac/dkl353 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract C. A. M. McNulty, J. Richards, D. M. Livermore, P. Little, A. Charlett, E. Freeman, I. Harvey, and M. Thomas

Clinical relevance of laboratory-reported antibiotic resistance in acute uncomplicated urinary tract infection in primary care
JAC Advance Access published on September 23, 2006
J. Antimicrob. Chemother. 2006 58: 1000-1008; doi:10.1093/jac/dkl368 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Jennifer Ford, Marta Boffito, Desmond Maitland, Andrew Hill, David Back, Saye Khoo, Mark Nelson, Graeme Moyle, Brian Gazzard, and Anton Pozniak

Influence of atazanavir 200 mg on the intracellular and plasma pharmacokinetics of saquinavir and ritonavir 1600/100 mg administered once daily in HIV-infected patients
JAC Advance Access published on September 19, 2006
J. Antimicrob. Chemother. 2006 58: 1009-1016; doi:10.1093/jac/dkl379 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Luis F. Lopez-Cortes, Rosa Ruiz-Valderas, Josefa Ruiz-Morales, Eva Leon, Antonio Vergara de Campos, Ana Marin-Niebla, Manuel Marquez-Solero, Fernando Lozano, and Rebeca Valiente

Efavirenz trough levels are not associated with virological failure throughout therapy with 800 mg daily and a rifampicin-containing antituberculosis regimen
JAC Advance Access published on September 6, 2006
J. Antimicrob. Chemother. 2006 58: 1017-1023; doi:10.1093/jac/dkl357 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Schlomo Staszewski, Errol Babacan, Christoph Stephan, Annette Haberl, Amina Carlebach, Peter Gute, Stephan Klauke, Yvonne Hermschulte, Martin Stuermer, Brenda Dauer, and for the Frankfurt HIV Cohort

The LOPSAQ study: 48 week analysis of a boosted double protease inhibitor regimen containing lopinavir/ritonavir plus saquinavir without additional antiretroviral therapy
JAC Advance Access published on September 6, 2006
J. Antimicrob. Chemother. 2006 58: 1024-1030; doi:10.1093/jac/dkl375 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Ming Shi, Rong Sheng Wang, Hua Zhang, Yu Fen Zhu, Bei Han, Yong Zhang, Li Ji Jin, Zhi-Jun Yang, and Yong Ping Xu

Sequential treatment with lamivudine and interferon- monotherapies in hepatitis B e antigen-negative Chinese patients and its suppression of lamivudine-resistant mutations
JAC Advance Access published on September 19, 2006
J. Antimicrob. Chemother. 2006 58: 1031-1035; doi:10.1093/jac/dkl385 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract R. S. Braithwaite, S. Shechter, M. S. Roberts, A. Schaefer, D. R. Bangsberg, P. R. Harrigan, and A. C. Justice

Explaining variability in the relationship between antiretroviral adherence and HIV mutation accumulation
JAC Advance Access published on October 5, 2006
J. Antimicrob. Chemother. 2006 58: 1036-1043; doi:10.1093/jac/dkl386 [Abstract] [FREE Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Brief reports

Get checked abstract Yvonne Agersø, Gisele Peirano, and Frank M. Aarestrup

dfrA25, a novel trimethoprim resistance gene from Salmonella Agona isolated from a human urine sample in Brazil
JAC Advance Access published on September 15, 2006
J. Antimicrob. Chemother. 2006 58: 1044-1047; doi:10.1093/jac/dkl366 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Olusegun O. Soge, Bolanle A. Adeniyi, and Marilyn C. Roberts

New antibiotic resistance genes associated with CTX-M plasmids from uropathogenic Nigerian Klebsiella pneumoniae
JAC Advance Access published on September 22, 2006
J. Antimicrob. Chemother. 2006 58: 1048-1053; doi:10.1093/jac/dkl370 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Vincent Cattoir, Philippe Lesprit, Christine Lascols, Erik Denamur, Patrick Legrand, Claude-James Soussy, and Emmanuelle Cambau

In vivo selection during ofloxacin therapy of Escherichia coli with combined topoisomerase mutations that confer high resistance to ofloxacin but susceptibility to nalidixic acid
JAC Advance Access published on September 19, 2006
J. Antimicrob. Chemother. 2006 58: 1054-1057; doi:10.1093/jac/dkl361 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Christina Kratzer, Selma Tobudic, Monika Schmoll, Wolfgang Graninger, and Apostolos Georgopoulos

In vitro activity and synergism of amphotericin B, azoles and cationic antimicrobials against the emerging pathogen Trichoderma spp.
JAC Advance Access published on September 19, 2006
J. Antimicrob. Chemother. 2006 58: 1058-1061; doi:10.1093/jac/dkl384 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Simon D. Baines, Katie Saxton, Jane Freeman, and Mark H. Wilcox

Tigecycline does not induce proliferation or cytotoxin production by epidemic Clostridium difficile strains in a human gut model
JAC Advance Access published on October 8, 2006
J. Antimicrob. Chemother. 2006 58: 1062-1065; doi:10.1093/jac/dkl364 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Manuel L. Fernández Guerrero and Miguel de Górgolas

Comparative activity of cloxacillin and vancomycin against methicillin-susceptible Staphylococcus aureus experimental endocarditis
JAC Advance Access published on August 24, 2006
J. Antimicrob. Chemother. 2006 58: 1066-1069; doi:10.1093/jac/dkl355 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Ashraf S. Ibrahim, John E. Edwards, Jr, Yue Fu, and Brad Spellberg

Deferiprone iron chelation as a novel therapy for experimental mucormycosis
JAC Advance Access published on August 23, 2006
J. Antimicrob. Chemother. 2006 58: 1070-1073; doi:10.1093/jac/dkl350 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Chen-Hsiang Lee, Lin-Hui Su, Ya-Fen Tang, and Jien-Wei Liu

Treatment of ESBL-producing Klebsiella pneumoniae bacteraemia with carbapenems or flomoxef: a retrospective study and laboratory analysis of the isolates
JAC Advance Access published on September 13, 2006
J. Antimicrob. Chemother. 2006 58: 1074-1077; doi:10.1093/jac/dkl381 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract John Ng, Iain B. Gosbell, John A. Kelly, Michael J. Boyle, and John K. Ferguson

Cure of multiresistant Acinetobacter baumannii central nervous system infections with intraventricular or intrathecal colistin: case series and literature review
JAC Advance Access published on August 17, 2006
J. Antimicrob. Chemother. 2006 58: 1078-1081; doi:10.1093/jac/dkl347 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract José A. Martínez, Josefa Aguilar, Manel Almela, Francesc Marco, Alex Soriano, Fina López, Valentina Balasso, Laura Pozo, and Josep Mensa

Prior use of carbapenems may be a significant risk factor for extended-spectrum ß-lactamase-producing Escherichia coli or Klebsiella spp. in patients with bacteraemia
JAC Advance Access published on September 1, 2006
J. Antimicrob. Chemother. 2006 58: 1082-1085; doi:10.1093/jac/dkl367 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Marco Bongiovanni, Fulvio Adorni, Maddalena Casana, Federica Tordato, Camilla Tincati, Paola Cicconi, Teresa Bini, and Antonella d'Arminio Monforte

Subclinical hypothyroidism in HIV-infected subjects
JAC Advance Access published on September 1, 2006
J. Antimicrob. Chemother. 2006 58: 1086-1089; doi:10.1093/jac/dkl360 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Get checked abstract Sarah Djabarouti, Dominique Breilh, Isabelle Pellegrin, Michel Lavit, Fabrice Camou, Olivier Caubet, Hervé Fleury, Marie-Claude Saux, and Jean-Luc Pellegrin

Intracellular and plasma efavirenz concentrations in HIV-infected patients switching from successful protease inhibitor-based highly active antiretroviral therapy (HAART) to efavirenz-based HAART (SUSTIPHAR Study)
JAC Advance Access published on August 18, 2006
J. Antimicrob. Chemother. 2006 58: 1090-1093; doi:10.1093/jac/dkl348 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence

Alexandre Prehn Zavascki

Comment on: Immune reconstitution inflammatory syndrome: more answers, more questions
JAC Advance Access published on September 14, 2006
J. Antimicrob. Chemother. 2006 58: 1094; doi:10.1093/jac/dkl362 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

S. A. Shelburne, M. Montes, and R. Hamill

Immune reconstitution inflammatory syndrome: more answers, more questions—authors' response
JAC Advance Access published on September 26, 2006
J. Antimicrob. Chemother. 2006 58: 1094-1095; doi:10.1093/jac/dkl390 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Daniela Ceccarelli, Stefania Bani, Piero Cappuccinelli, and Mauro Maria Colombo

Prevalence of aadA1 and dfrA15 class 1 integron cassettes and SXT circulation in Vibrio cholerae O1 isolates from Africa
JAC Advance Access published on September 15, 2006
J. Antimicrob. Chemother. 2006 58: 1095-1097; doi:10.1093/jac/dkl352 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Céline Pulcini

Comment on: Non-adherence to infectious diseases consultations: are surgeons to blame?
JAC Advance Access published on September 1, 2006
J. Antimicrob. Chemother. 2006 58: 1095; doi:10.1093/jac/dkl371 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Athanassios Tsakris, Alexandros Ikonomidis, Spyros Pournaras, Nicholas Spanakis, and Antonios Markogiannakis

Carriage of OXA-58 but not of OXA-51 ß-lactamase gene correlates with carbapenem resistance in Acinetobacter baumannii
JAC Advance Access published on September 22, 2006
J. Antimicrob. Chemother. 2006 58: 1097-1099; doi:10.1093/jac/dkl365 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Harald Seifert, Danuta Stefanik, and Hilmar Wisplinghoff

Comparative in vitro activities of tigecycline and 11 other antimicrobial agents against 215 epidemiologically defined multidrug-resistant Acinetobacter baumannii isolates
JAC Advance Access published on September 14, 2006
J. Antimicrob. Chemother. 2006 58: 1099-1100; doi:10.1093/jac/dkl383 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

T. W. Boo, F. Walsh, and B. Crowley

First report of OXA-23 carbapenemase in clinical isolates of Acinetobacter species in the Irish Republic
JAC Advance Access published on August 17, 2006
J. Antimicrob. Chemother. 2006 58: 1101-1102; doi:10.1093/jac/dkl345 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Suppiah Paramalingam Sivalingam, Siew Hoon Sim, Lay Tin Aw, and Eng Eong Ooi

Antibiotic susceptibility of 50 clinical isolates of Burkholderia pseudomallei from Singapore
JAC Advance Access published on September 2, 2006
J. Antimicrob. Chemother. 2006 58: 1102-1103; doi:10.1093/jac/dkl359 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Erik Glocker and Manfred Kist

Emergence of a Helicobacter pylori isolate with reduced susceptibility to tetracycline in Germany
JAC Advance Access published on August 18, 2006
J. Antimicrob. Chemother. 2006 58: 1103-1104; doi:10.1093/jac/dkl346 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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