Journal of Antimicrobial Chemotherapy

Leading articles:

Mark A. Toleman, Peter M. Bennett, and Timothy R. Walsh

Common regions e.g. orf513 and antibiotic resistance: IS91-like elements evolving complex class 1 integrons
JAC Advance Access published on June 2, 2006
J. Antimicrob. Chemother. 2006 58: 1-6; doi:10.1093/jac/dkl204 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Diego Rincón, Cristina Ripoll, María Vega Catalina, Magdalena Salcedo, and Rafael Bañares

Does interferon improve portal hypertension?
JAC Advance Access published on May 23, 2006
J. Antimicrob. Chemother. 2006 58: 7-12; doi:10.1093/jac/dkl170 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Corinna Kehrenberg, Danièle Meunier, Hayette Targant, Axel Cloeckaert, Stefan Schwarz, and Jean-Yves Madec

Plasmid-mediated florfenicol resistance in Pasteurella trehalosi
JAC Advance Access published on May 2, 2006
J. Antimicrob. Chemother. 2006 58: 13-17; doi:10.1093/jac/dkl174 [Abstract] [Full Text] [PDF] [Request Permissions]  

Corinna Kehrenberg, Sonja Friederichs, Anno de Jong, Geovana Brenner Michael, and Stefan Schwarz

Identification of the plasmid-borne quinolone resistance gene qnrS in Salmonella enterica serovar Infantis
JAC Advance Access published on May 23, 2006
J. Antimicrob. Chemother. 2006 58: 18-22; doi:10.1093/jac/dkl213 [Abstract] [Full Text] [PDF] [Request Permissions]  

Duarte C. Oliveira, Catarina Milheiriço, Susana Vinga, and Hermínia de Lencastre

Assessment of allelic variation in the ccrAB locus in methicillin-resistant Staphylococcus aureus clones
JAC Advance Access published on May 30, 2006
J. Antimicrob. Chemother. 2006 58: 23-30; doi:10.1093/jac/dkl208 [Abstract] [Full Text] [PDF] Supplementary Data [Request Permissions]  

Ricardo E. de Cristóbal, Paula A. Vincent, and Raúl A. Salomón

Multidrug resistance pump AcrAB-TolC is required for high-level, Tet(A)-mediated tetracycline resistance in Escherichia coli
JAC Advance Access published on May 10, 2006
J. Antimicrob. Chemother. 2006 58: 31-36; doi:10.1093/jac/dkl172 [Abstract] [Full Text] [PDF] [Request Permissions]  

Lilian Pumbwe, Ohmi Ueda, Fuminobu Yoshimura, Abraham Chang, Rachel L. Smith, and Hannah M. Wexler

Bacteroides fragilis BmeABC efflux systems additively confer intrinsic antimicrobial resistance
JAC Advance Access published on June 6, 2006
J. Antimicrob. Chemother. 2006 58: 37-46; doi:10.1093/jac/dkl202 [Abstract] [Full Text] [PDF] [Request Permissions]  

Michelle L. Gatton and Qin Cheng

Plasmodium falciparum infection dynamics and transmission potential following treatment with sulfadoxine-pyrimethamine
JAC Advance Access published on April 26, 2006
J. Antimicrob. Chemother. 2006 58: 47-51; doi:10.1093/jac/dkl158 [Abstract] [Full Text] [PDF] [Request Permissions]  

Sonja Maerki, Reto Brun, Susan A. Charman, Arnulf Dorn, Hugues Matile, and Sergio Wittlin

In vitro assessment of the pharmacodynamic properties and the partitioning of OZ277/RBx-11160 in cultures of Plasmodium falciparum
JAC Advance Access published on May 30, 2006
J. Antimicrob. Chemother. 2006 58: 52-58; doi:10.1093/jac/dkl209 [Abstract] [Full Text] [PDF] [Request Permissions]  

Érica S. Martins-Duarte, Julio A. Urbina, Wanderley de Souza, and Rossiane C. Vommaro

Antiproliferative activities of two novel quinuclidine inhibitors against Toxoplasma gondii tachyzoites in vitro
JAC Advance Access published on May 15, 2006
J. Antimicrob. Chemother. 2006 58: 59-65; doi:10.1093/jac/dkl180 [Abstract] [Full Text] [PDF] [Request Permissions]  

Nilton Lincopan and Ana M. Carmona-Ribeiro

Lipid-covered drug particles: combined action of dioctadecyldimethylammonium bromide and amphotericin B or miconazole
JAC Advance Access published on April 24, 2006
J. Antimicrob. Chemother. 2006 58: 66-75; doi:10.1093/jac/dkl153 [Abstract] [Full Text] [PDF] [Request Permissions]  

Elena Banfi, Giuditta Scialino, Daniele Zampieri, Maria Grazia Mamolo, Luciano Vio, Marco Ferrone, Maurizio Fermeglia, Maria Silvia Paneni, and Sabrina Pricl

Antifungal and antimycobacterial activity of new imidazole and triazole derivatives. A combined experimental and computational approach
JAC Advance Access published on May 18, 2006
J. Antimicrob. Chemother. 2006 58: 76-84; doi:10.1093/jac/dkl182 [Abstract] [Full Text] [PDF] Colour figures [Request Permissions]  

L. Masco, K. Van Hoorde, E. De Brandt, J. Swings, and G. Huys

Antimicrobial susceptibility of Bifidobacterium strains from humans, animals and probiotic products
JAC Advance Access published on May 12, 2006
J. Antimicrob. Chemother. 2006 58: 85-94; doi:10.1093/jac/dkl197 [Abstract] [Full Text] [PDF] [Request Permissions]  

María Jesús Rodríguez-Hernández, José Saugar, Fernando Docobo-Pérez, Beatriz G. de la Torre, María Eugenia Pachón-Ibáñez, Andrés García-Curiel, Felipe Fernández-Cuenca, David Andreu, Luis Rivas, and Jerónimo Pachón

Studies on the antimicrobial activity of cecropin A–melittin hybrid peptides in colistin-resistant clinical isolates of Acinetobacter baumannii
JAC Advance Access published on April 24, 2006
J. Antimicrob. Chemother. 2006 58: 95-100; doi:10.1093/jac/dkl145 [Abstract] [Full Text] [PDF] [Request Permissions]  

Vibeke F. Jensen, Lotte Jakobsen, Hanne-Dorthe Emborg, Anne Mette Seyfarth, and Anette M. Hammerum

Correlation between apramycin and gentamicin use in pigs and an increasing reservoir of gentamicin-resistant Escherichia coli
JAC Advance Access published on May 18, 2006
J. Antimicrob. Chemother. 2006 58: 101-107; doi:10.1093/jac/dkl201 [Abstract] [Full Text] [PDF] [Request Permissions]  

Jeremy A. Schafer, Laurie B. Hovde, and John C. Rotschafer

Consistent rates of kill of Staphylococcus aureus by gentamicin over a 6-fold clinical concentration range in an in vitro pharmacodynamic model (IVPDM)
JAC Advance Access published on May 30, 2006
J. Antimicrob. Chemother. 2006 58: 108-111; doi:10.1093/jac/dkl216 [Abstract] [Full Text] [PDF] [Request Permissions]  

George G. Zhanel, Joanne James, Sheldon Derkatch, Nancy Laing, Ayman M. Noreddin, and Daryl J. Hoban

Pharmacodynamic activity of garenoxacin against ciprofloxacin-resistant Streptococcus pneumoniae
JAC Advance Access published on April 27, 2006
J. Antimicrob. Chemother. 2006 58: 112-116; doi:10.1093/jac/dkl159 [Abstract] [Full Text] [PDF] [Request Permissions]  

Shiranee Sriskandan, Melissa Ferguson, Victoria Elliot, Lee Faulkner, and Jonathan Cohen

Human intravenous immunoglobulin for experimental streptococcal toxic shock: bacterial clearance and modulation of inflammation
JAC Advance Access published on May 2, 2006
J. Antimicrob. Chemother. 2006 58: 117-124; doi:10.1093/jac/dkl173 [Abstract] [Full Text] [PDF] [Request Permissions]  

Masood A. Khan and Mohd Owais

Toxicity, stability and pharmacokinetics of amphotericin B in immunomodulator tuftsin-bearing liposomes in a murine model
JAC Advance Access published on May 18, 2006
J. Antimicrob. Chemother. 2006 58: 125-132; doi:10.1093/jac/dkl177 [Abstract] [Full Text] [PDF] [Request Permissions]  

Juan José Ríos Blanco, Inés Suárez García, Jorge Gómez Cerezo, José María Peña Sánchez de Rivera, Pilar Moreno Anaya, Pilar García Raya, Juan González García, José Ramón Arribas López, Francisco Javier Barbado Hernández, and Juan José Vázquez Rodríguez

Endothelial function in HIV-infected patients with low or mild cardiovascular risk
JAC Advance Access published on May 15, 2006
J. Antimicrob. Chemother. 2006 58: 133-139; doi:10.1093/jac/dkl190 [Abstract] [Full Text] [PDF] [Request Permissions]  

José A. Mira, Juan Macías, José A. Girón-González, Dolores Merino, Mercedes González-Serrano, Manuel E. Jiménez-Mejías, Francisco J. Caballero-Granado, Julián Torre-Cisneros, Alberto Terrón, Mark I. Becker, Jesús Gómez-Mateos, Ana Arizcorreta-Yarza, Juan A. Pineda, and for the Grupo Andaluz Para el Estudio de las Enfermedades Infecciosas (GAEI)

Incidence of and risk factors for severe hepatotoxicity of nelfinavir-containing regimens among HIV-infected patients with chronic hepatitis C
JAC Advance Access published on May 23, 2006
J. Antimicrob. Chemother. 2006 58: 140-146; doi:10.1093/jac/dkl214 [Abstract] [Full Text] [PDF] [Request Permissions]  

Mark Oette, Arne Kroidl, Klaus Göbels, Antje Stabbert, Marion Menge, Abdurrahman Sagir, Dieter Kuschak, Tara O'Hanley, Johannes G. Bode, and Dieter Häussinger

Predictors of short-term success of antiretroviral therapy in HIV infection
JAC Advance Access published on May 10, 2006
J. Antimicrob. Chemother. 2006 58: 147-153; doi:10.1093/jac/dkl189 [Abstract] [Full Text] [PDF] [Request Permissions]  

Graeme N. Forrest, Sanjay Mehta, Elizabeth Weekes, Durry P. Lincalis, Jennifer K. Johnson, and Richard A. Venezia

Impact of rapid in situ hybridization testing on coagulase-negative staphylococci positive blood cultures
JAC Advance Access published on April 24, 2006
J. Antimicrob. Chemother. 2006 58: 154-158; doi:10.1093/jac/dkl146 [Abstract] [Full Text] [PDF] [Request Permissions]  

R. H. Vander Stichele, M. M. Elseviers, M. Ferech, S. Blot, H. Goossens, and on behalf of the European Surveillance of Antibiotic Consumption (ESAC) Project Group

Hospital consumption of antibiotics in 15 European countries: results of the ESAC Retrospective Data Collection (1997–2002)
JAC Advance Access published on May 12, 2006
J. Antimicrob. Chemother. 2006 58: 159-167; doi:10.1093/jac/dkl147 [Abstract] [Full Text] [PDF] Supplementary Data [Request Permissions]  

Brief reports:

Cédric Cagliero, Lucie Cloix, Axel Cloeckaert, and Sophie Payot

High genetic variation in the multidrug transporter cmeB gene in Campylobacter jejuni and Campylobacter coli
JAC Advance Access published on May 30, 2006
J. Antimicrob. Chemother. 2006 58: 168-172; doi:10.1093/jac/dkl212 [Abstract] [Full Text] [PDF] [Request Permissions]  

Rebeccah M. Travis, Carlton L. Gyles, Richard Reid-Smith, Cornelis Poppe, Scott A. McEwen, Robert Friendship, Nicol Janecko, and Patrick Boerlin

Chloramphenicol and kanamycin resistance among porcine Escherichia coli in Ontario
JAC Advance Access published on May 23, 2006
J. Antimicrob. Chemother. 2006 58: 173-177; doi:10.1093/jac/dkl207 [Abstract] [Full Text] [PDF] [Request Permissions]  

Thierry Naas, Pierre Bogaerts, Caroline Bauraing, Yves Degheldre, Youri Glupczynski, and Patrice Nordmann

Emergence of PER and VEB extended-spectrum ß-lactamases in Acinetobacter baumannii in Belgium
JAC Advance Access published on May 2, 2006
J. Antimicrob. Chemother. 2006 58: 178-182; doi:10.1093/jac/dkl178 [Abstract] [Full Text] [PDF] [Request Permissions]  

Stephen G. Tristram and Scott Nichols

A multiplex PCR for ß-lactamase genes of Haemophilus influenzae and description of a new bla_TEM promoter variant
JAC Advance Access published on April 26, 2006
J. Antimicrob. Chemother. 2006 58: 183-185; doi:10.1093/jac/dkl150 [Abstract] [Full Text] [PDF] [Request Permissions]  

R. Charlesworth, M. Warner, D. M. Livermore, and A. P. R. Wilson

Comparison of four methods for detection of teicoplanin resistance in methicillin-resistant Staphylococcus aureus
JAC Advance Access published on April 26, 2006
J. Antimicrob. Chemother. 2006 58: 186-189; doi:10.1093/jac/dkl151 [Abstract] [Full Text] [PDF] [Request Permissions]  

Daniel Metcalf, Colin Robinson, Deirdre Devine, and Simon Wood

Enhancement of erythrosine-mediated photodynamic therapy of Streptococcus mutans biofilms by light fractionation
JAC Advance Access published on May 30, 2006
J. Antimicrob. Chemother. 2006 58: 190-192; doi:10.1093/jac/dkl205 [Abstract] [Full Text] [PDF] [Request Permissions]  

Astrid Buxbaum, Christina Kratzer, Wolfgang Graninger, and Apostolos Georgopoulos

Antimicrobial and toxicological profile of the new biocide Akacid plus®
JAC Advance Access published on June 2, 2006
J. Antimicrob. Chemother. 2006 58: 193-197; doi:10.1093/jac/dkl206 [Abstract] [Full Text] [PDF] [Request Permissions]  

H. Altman, D. Steinberg, Y. Porat, A. Mor, D. Fridman, M. Friedman, and G. Bachrach

In vitro assessment of antimicrobial peptides as potential agents against several oral bacteria
JAC Advance Access published on May 10, 2006
J. Antimicrob. Chemother. 2006 58: 198-201; doi:10.1093/jac/dkl181 [Abstract] [Full Text] [PDF] [Request Permissions]  

Heather J. Adam, Kristen N. Schurek, Melanie R. DeCorby, Barbara Weshnoweski, Ravinder Vashisht, Kathy Karlowsky, Daryl J. Hoban, and George G. Zhanel

Comparative in vitro activity of PGE 9262932 and fluoroquinolones against Canadian clinical Streptococcus pneumoniae isolates, including molecularly characterized ciprofloxacin-resistant isolates
JAC Advance Access published on April 24, 2006
J. Antimicrob. Chemother. 2006 58: 202-204; doi:10.1093/jac/dkl152 [Abstract] [Full Text] [PDF] [Request Permissions]  

Flávia Rossi, Fernando Baquero, Po-Ren Hsueh, David L. Paterson, Grant V. Bochicchio, Theresa A. Snyder, Vilas Satishchandran, Kathleen McCarroll, Mark J. DiNubile, and Joseph W. Chow

In vitro susceptibilities of aerobic and facultatively anaerobic Gram-negative bacilli isolated from patients with intra-abdominal infections worldwide: 2004 results from SMART (Study for Monitoring Antimicrobial Resistance Trends)
JAC Advance Access published on May 22, 2006
J. Antimicrob. Chemother. 2006 58: 205-210; doi:10.1093/jac/dkl199 [Abstract] [Full Text] [PDF] [Request Permissions]  

Raúl Jesús Mesa, Vanessa Blanc, Anicet R. Blanch, Pilar Cortés, Juan José González, Susana Lavilla, Elisenda Miró, Maite Muniesa, Montserrat Saco, Ma Teresa Tórtola, Beatriz Mirelis, Pere Coll, Montserrat Llagostera, Guillem Prats, and Ferran Navarro

Extended-spectrum ß-lactamase-producing Enterobacteriaceae in different environments (humans, food, animal farms and sewage)
JAC Advance Access published on May 23, 2006
J. Antimicrob. Chemother. 2006 58: 211-215; doi:10.1093/jac/dkl211 [Abstract] [Full Text] [PDF] [Request Permissions]  

Ximena Coronado, Inés Zulantay, Marlene Rozas, Werner Apt, Gittith Sánchez, Jorge Rodríguez, Sylvia Ortiz, and Aldo Solari

Dissimilar distribution of Trypanosoma cruzi clones in humans after chemotherapy with allopurinol and itraconazole
JAC Advance Access published on May 22, 2006
J. Antimicrob. Chemother. 2006 58: 216-219; doi:10.1093/jac/dkl192 [Abstract] [Full Text] [PDF] [Request Permissions]  

Correspondence:

Leonard Leibovici and Mical Paul

Comment on Guidelines for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in the UK
JAC Advance Access published on April 6, 2006
J. Antimicrob. Chemother. 2006 58: 220; doi:10.1093/jac/dkl143 [Extract] [Full Text] [PDF] [Request Permissions]  

Peter L. Anderson and Thomas N. Kakuda

Comment on: Suboptimal CD4 gains in HIV-infected patients receiving didanosine plus tenofovir
JAC Advance Access published on May 22, 2006
J. Antimicrob. Chemother. 2006 58: 220-221; doi:10.1093/jac/dkl203 [Extract] [Full Text] [PDF] [Request Permissions]  

Jian Li and Roger L. Nation

Comment on: Pharmacokinetics of inhaled colistin in patients with cystic fibrosis
JAC Advance Access published on April 26, 2006
J. Antimicrob. Chemother. 2006 58: 222-223; doi:10.1093/jac/dkl169 [Extract] [Full Text] [PDF] [Request Permissions]  

F. Ratjen, H. Beier, and H. Grasemann

Pharmacokinetics of inhaled colistin in patients with cystic fibrosis: authors' response
JAC Advance Access published on May 15, 2006
J. Antimicrob. Chemother. 2006 58: 223; doi:10.1093/jac/dkl195 [Extract] [Full Text] [PDF] [Request Permissions]  

N. P. Brenwald, J. Andrews, and A. P. Fraise

Activity of mecillinam against AmpC ß-lactamase-producing Escherichia coli
JAC Advance Access published on May 12, 2006
J. Antimicrob. Chemother. 2006 58: 223-224; doi:10.1093/jac/dkl198 [Extract] [Full Text] [PDF] [Request Permissions]  

David A. Boyd and Michael R. Mulvey

OXA-1 is OXA-30 is OXA-1
JAC Advance Access published on May 30, 2006
J. Antimicrob. Chemother. 2006 58: 224-225; doi:10.1093/jac/dkl154 [Extract] [Full Text] [PDF] [Request Permissions]  

Kristina Kadlec, Corinna Kehrenberg, and Stefan Schwarz

tet(A)-mediated tetracycline resistance in porcine Bordetella bronchiseptica isolates is based on plasmid-borne Tn1721 relics
JAC Advance Access published on April 24, 2006
J. Antimicrob. Chemother. 2006 58: 225-227; doi:10.1093/jac/dkl149 [Extract] [Full Text] [PDF] [Request Permissions]  

Katrina Pollock, Justin Stebbing, Mark Bower, Brian Gazzard, and Mark Nelson

Emtricitabine intolerance in treatment-experienced patients switched from lamivudine: a method of assessing toxicity
JAC Advance Access published on May 9, 2006
J. Antimicrob. Chemother. 2006 58: 227-228; doi:10.1093/jac/dkl179 [Extract] [Full Text] [PDF] [Request Permissions]  

R. Zarychanski, K. Wlodarczyk, R. Ariano, and E. Bow

Pharmacokinetic interaction between methotrexate and piperacillin/tazobactam resulting in prolonged toxic concentrations of methotrexate
JAC Advance Access published on May 22, 2006
J. Antimicrob. Chemother. 2006 58: 228-230; doi:10.1093/jac/dkl196 [Extract] [Full Text] [PDF] [Request Permissions]  

Book reviews:

C. A. Hart

Pocket Guide to Extended-Spectrum ß-Lactamases in Resistance • D. M. Livermore and D. L. Paterson • Current Medicine Group, London, UK, 2006. • ISBN 1-85873-859-8. 64 pp
JAC Advance Access published on April 26, 2006
J. Antimicrob. Chemother. 2006 58: 231; doi:10.1093/jac/dkl176 [Extract] [Full Text] [PDF] [Request Permissions]  

Alan Johnson

Antimicrobial Agents: Antibacterials and Antifungals • Andre Bryskier, Ed. • ASM Press, Washington, USA, 2005. • ISBN 1-55581-237-6. $189.95, 1456 pp.
JAC Advance Access published on May 23, 2006
J. Antimicrob. Chemother. 2006 58: 231; doi:10.1093/jac/dkl218 [Extract] [Full Text] [PDF] [Request Permissions]  

Jeremy Hamilton-Miller

Probiotics and prebiotics: scientific aspects • G. W. Tannock, Ed. Caister Academic Press, Wymondham, UK, 2005. • ISBN 1-904455-01-8. £99, 230 pp
JAC Advance Access published on April 26, 2006
J. Antimicrob. Chemother. 2006 58: 232-233; doi:10.1093/jac/dkl171 [Extract] [Full Text] [PDF] [Request Permissions]  

I. M. Gould

Frontiers in Antimicrobial Resistance: A Tribute to Stuart B. Levy • David G. White, Michael N. Alekshun and • Patrick F. Mcdermott, Eds. • ASM Press, USA, 2005. • ISBN 1-55581-329-1. $119.95, 598 pp.
JAC Advance Access published on June 2, 2006
J. Antimicrob. Chemother. 2006 58: 232; doi:10.1093/jac/dkl194 [Extract] [Full Text] [PDF] [Request Permissions]  

A.A. Glynn

Museum review • Alexander Fleming Laboratory Museum • St Mary's Hospital, Praed Street, London W2 1NY, UK [Curator: Kevin Brown]
JAC Advance Access published on April 26, 2006
J. Antimicrob. Chemother. 2006 58: 233-234; doi:10.1093/jac/dkl148 [Extract] [Full Text] [PDF] [Request Permissions]  

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