Journal of Antimicrobial Chemotherapy

Editorial:

David Reeves

Another set of endocarditis guidelines?
JAC Advance Access published on April 19, 2006
J. Antimicrob. Chemother. 2006 57: 1023; doi:10.1093/jac/dkl118 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Leading articles:

Richard Wise

Antimicrobial resistance: paradox, actions and economics
JAC Advance Access published on April 19, 2006
J. Antimicrob. Chemother. 2006 57: 1024-1025; doi:10.1093/jac/dkl138 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Matthew J. Ellington and Neil Woodford

Fluoroquinolone resistance and plasmid addiction systems: self-imposed selection pressure?
JAC Advance Access published on April 3, 2006
J. Antimicrob. Chemother. 2006 57: 1026-1029; doi:10.1093/jac/dkl110 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Melissa K. Osborn and Anna S. F. Lok

Antiviral options for the treatment of chronic hepatitis B
JAC Advance Access published on April 4, 2006
J. Antimicrob. Chemother. 2006 57: 1030-1034; doi:10.1093/jac/dkl123 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Reviews:

F. K. Gould, T. S. J. Elliott, J. Foweraker, M. Fulford, J. D. Perry, G. J. Roberts, J. A. T. Sandoe, and R. W. Watkin

Guidelines for the prevention of endocarditis: report of the Working Party of the British Society for Antimicrobial Chemotherapy
JAC Advance Access published on April 19, 2006
J. Antimicrob. Chemother. 2006 57: 1035-1042; doi:10.1093/jac/dkl121 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Alexis Nzila

The past, present and future of antifolates in the treatment of Plasmodium falciparum infection
JAC Advance Access published on April 14, 2006
J. Antimicrob. Chemother. 2006 57: 1043-1054; doi:10.1093/jac/dkl104 [Abstract] [Full Text] [PDF] [Request Permissions]  

G. Carosi, C. Torti, M. Andreoni, G. Angarano, A. Antinori, S. Bonora, M. Borderi, A. Castagna, F. Castelli, R. Cauda, F. Chiodo, A. D'arminio-Monforte, A. De Luca, G. Di Perri, F. Dianzani, G. Filice, M. Galli, A. Lazzarin, F. Maggiolo, R. Maserati, F. Mazzotta, M. Moroni, C. F. Perno, and V. Vullo on behalf of the Members of the Italian HIV Guidelines Working Group

Key questions in antiretroviral therapy: Italian Consensus Workshop (2005)
JAC Advance Access published on April 10, 2006
J. Antimicrob. Chemother. 2006 57: 1055-1064; doi:10.1093/jac/dkl113 [Abstract] [Full Text] [PDF] [Request Permissions]  

Original articles:

Kayode K. Ojo, Nevada L. Ruehlen, Natasha S. Close, Henrique Luis, Mario Bernardo, Jorge Leitao, and Marilyn C. Roberts

The presence of a conjugative Gram-positive Tn2009 in Gram-negative commensal bacteria
JAC Advance Access published on March 21, 2006
J. Antimicrob. Chemother. 2006 57: 1065-1069; doi:10.1093/jac/dkl094 [Abstract] [Full Text] [PDF] [Request Permissions]  

Virginia C. Gould and Matthew B. Avison

SmeDEF-mediated antimicrobial drug resistance in Stenotrophomonas maltophilia clinical isolates having defined phylogenetic relationships
JAC Advance Access published on April 5, 2006
J. Antimicrob. Chemother. 2006 57: 1070-1076; doi:10.1093/jac/dkl106 [Abstract] [Full Text] [PDF] [Request Permissions]  

Keiko Hasegawa, Reiko Kobayashi, Emi Takada, Akiko Ono, Naoko Chiba, Miyuki Morozumi, Satoshi Iwata, Keisuke Sunakawa, and Kimiko Ubukata on behalf of the Working Group of the Nationwide Surveillance for Bacterial Meningitis

High prevalence of type b ß-lactamase-non-producing ampicillin-resistant Haemophilus influenzae in meningitis: the situation in Japan where Hib vaccine has not been introduced
JAC Advance Access published on April 14, 2006
J. Antimicrob. Chemother. 2006 57: 1077-1082; doi:10.1093/jac/dkl142 [Abstract] [Full Text] [PDF] [Request Permissions]  

María Dolores Navarro-Martínez, Francisco García-Cánovas, and José Neptuno Rodríguez-López

Tea polyphenol epigallocatechin-3-gallate inhibits ergosterol synthesis by disturbing folic acid metabolism in Candida albicans
JAC Advance Access published on April 3, 2006
J. Antimicrob. Chemother. 2006 57: 1083-1092; doi:10.1093/jac/dkl124 [Abstract] [Full Text] [PDF] [Request Permissions]  

B. Pradines, A. Tall, F. Ramiandrasoa, A. Spiegel, C. Sokhna, T. Fusai, J. Mosnier, W. Daries, J. F. Trape, G. Kunesch, D. Parzy, and C. Rogier

In vitro activity of iron-binding compounds against Senegalese isolates of Plasmodium falciparum
JAC Advance Access published on April 4, 2006
J. Antimicrob. Chemother. 2006 57: 1093-1099; doi:10.1093/jac/dkl117 [Abstract] [Full Text] [PDF] [Request Permissions]  

Guo-Xian Wei, Alexander N. Campagna, and Libuse A. Bobek

Effect of MUC7 peptides on the growth of bacteria and on Streptococcus mutans biofilm
JAC Advance Access published on April 4, 2006
J. Antimicrob. Chemother. 2006 57: 1100-1109; doi:10.1093/jac/dkl120 [Abstract] [Full Text] [PDF] [Request Permissions]  

Ji-Young Lee, Kwan Soo Ko, Kyong Ran Peck, Won Sup Oh, and Jae-Hoon Song

In vitro evaluation of the antibiotic lock technique (ALT) for the treatment of catheter-related infections caused by staphylococci
JAC Advance Access published on March 23, 2006
J. Antimicrob. Chemother. 2006 57: 1110-1115; doi:10.1093/jac/dkl098 [Abstract] [Full Text] [PDF] [Request Permissions]  

Sara K. Olofsson, Linda L. Marcusson, Patricia Komp Lindgren, Diarmaid Hughes, and Otto Cars

Selection of ciprofloxacin resistance in Escherichia coli in an in vitro kinetic model: relation between drug exposure and mutant prevention concentration
JAC Advance Access published on April 19, 2006
J. Antimicrob. Chemother. 2006 57: 1116-1121; doi:10.1093/jac/dkl135 [Abstract] [Full Text] [PDF] [Request Permissions]  

Dong Taek Cho, Hwa Yun Cha, Hyun-Ha Chang, Shin-Woo Kim, Jae Myung Chung, Jungmin Kim, Yoo Chul Lee, Sung Yong Seol, and Je Chul Lee

Risk factors for specific methicillin-resistant Staphylococcus aureus clones in a Korean hospital
JAC Advance Access published on March 31, 2006
J. Antimicrob. Chemother. 2006 57: 1122-1127; doi:10.1093/jac/dkl114 [Abstract] [Full Text] [PDF] [Request Permissions]  

David Sevillano, Luis Alou, Lorenzo Aguilar, Olatz Echevarría, María-José Giménez, and José Prieto

Azithromycin iv pharmacodynamic parameters predicting Streptococcus pneumoniae killing in epithelial lining fluid versus serum: an in vitro pharmacodynamic simulation
JAC Advance Access published on April 14, 2006
J. Antimicrob. Chemother. 2006 57: 1128-1133; doi:10.1093/jac/dkl140 [Abstract] [Full Text] [PDF] [Request Permissions]  

Vadim Makarov, Olga B. Riabova, Anatoly Yuschenko, Nailya Urlyapova, Adilya Daudova, Peter F. Zipfel, and Ute Möllmann

Synthesis and antileprosy activity of some dialkyldithiocarbamates
JAC Advance Access published on April 4, 2006
J. Antimicrob. Chemother. 2006 57: 1134-1138; doi:10.1093/jac/dkl095 [Abstract] [Full Text] [PDF] [Request Permissions]  

Jennifer Keiser, Xiao Shu-Hua, Marcel Tanner, and Jürg Utzinger

Artesunate and artemether are effective fasciolicides in the rat model and in vitro
JAC Advance Access published on March 31, 2006
J. Antimicrob. Chemother. 2006 57: 1139-1145; doi:10.1093/jac/dkl125 [Abstract] [Full Text] [PDF] [Request Permissions]  

Rajesh Pandey and G. K. Khuller

Oral nanoparticle-based antituberculosis drug delivery to the brain in an experimental model
JAC Advance Access published on April 5, 2006
J. Antimicrob. Chemother. 2006 57: 1146-1152; doi:10.1093/jac/dkl128 [Abstract] [Full Text] [PDF] [Request Permissions]  

Helene Vogelsinger, Stefan Weiler, Angela Djanani, Jordan Kountchev, Rosa Bellmann-Weiler, Christian J. Wiedermann, and Romuald Bellmann

Amphotericin B tissue distribution in autopsy material after treatment with liposomal amphotericin B and amphotericin B colloidal dispersion
JAC Advance Access published on April 20, 2006
J. Antimicrob. Chemother. 2006 57: 1153-1160; doi:10.1093/jac/dkl141 [Abstract] [Full Text] [PDF] [Request Permissions]  

Mark A. Boyd, Umaporn Siangphoe, Kiat Ruxrungtham, Peter Reiss, Apicha Mahanontharit, Joep M. A. Lange, Praphan Phanuphak, David A. Cooper, and David M. Burger

The use of pharmacokinetically guided indinavir dose reductions in the management of indinavir-associated renal toxicity
JAC Advance Access published on April 4, 2006
J. Antimicrob. Chemother. 2006 57: 1161-1167; doi:10.1093/jac/dkl112 [Abstract] [Full Text] [PDF] [Request Permissions]  

Raffaella Rosso, Antonio Di Biagio, Chiara Dentone, Guido Castelli Gattinara, Alessandra Maria Martino, Alessandra Viganò, Marzia Merlo, Carlo Giaquinto, Osvalda Rampon, Matteo Bassetti, Giorgio Gatti, and Claudio Viscoli

Lopinavir/ritonavir exposure in treatment-naive HIV-infected children following twice or once daily administration
JAC Advance Access published on April 10, 2006
J. Antimicrob. Chemother. 2006 57: 1168-1171; doi:10.1093/jac/dkl136 [Abstract] [Full Text] [PDF] [Request Permissions]  

Nuria Fernandez-Hidalgo, Benito Almirante, Raquel Calleja, Isabel Ruiz, Ana M. Planes, Dolors Rodriguez, Carles Pigrau, and Albert Pahissa

Antibiotic-lock therapy for long-term intravascular catheter-related bacteraemia: results of an open, non-comparative study
JAC Advance Access published on April 5, 2006
J. Antimicrob. Chemother. 2006 57: 1172-1180; doi:10.1093/jac/dkl103 [Abstract] [Full Text] [PDF] [Request Permissions]  

Chien-Yuan Chen, Ritesh N. Kumar, Yin-Hsun Feng, Chao-Hung Ho, Jie-Yu You, Chi-Chou Liao, Chiung-Hui Tseng, Panagiotis Mavros, William C. Gerth, and Yee-Chun Chen

Treatment outcomes in patients receiving conventional amphotericin B therapy: a prospective multicentre study in Taiwan
JAC Advance Access published on April 4, 2006
J. Antimicrob. Chemother. 2006 57: 1181-1188; doi:10.1093/jac/dkl107 [Abstract] [Full Text] [PDF] [Request Permissions]  

Antimicrobial practice:

Dilip Nathwani on behalf of Scottish Medicines Consortium (SMC) Short Life Working Group, The Scottish Executive Health Department Healthcare Associated Infection Task Force

Antimicrobial prescribing policy and practice in Scotland: recommendations for good antimicrobial practice in acute hospitals
JAC Advance Access published on April 19, 2006
J. Antimicrob. Chemother. 2006 57: 1189-1196; doi:10.1093/jac/dkl137 [Abstract] [Full Text] [PDF] Supplementary Data [Request Permissions]  

Alberto Sandiumenge, Emili Diaz, Alejandro Rodriguez, Loreto Vidaur, Laura Canadell, Montserrat Olona, Montserrat Rue, and Jordi Rello

Impact of diversity of antibiotic use on the development of antimicrobial resistance
JAC Advance Access published on March 24, 2006
J. Antimicrob. Chemother. 2006 57: 1197-1204; doi:10.1093/jac/dkl097 [Abstract] [Full Text] [PDF] [Request Permissions]  

Brief reports:

Patrizia Spigaglia, Fabrizio Barbanti, and Paola Mastrantonio

New variants of the tet(M) gene in Clostridium difficile clinical isolates harbouring Tn916-like elements
JAC Advance Access published on March 24, 2006
J. Antimicrob. Chemother. 2006 57: 1205-1209; doi:10.1093/jac/dkl105 [Abstract] [Full Text] [PDF] [Request Permissions]  

Beatriz Guerra, Ernst Junker, Andreas Schroeter, Reiner Helmuth, Beatriz E. C. Guth, and Lothar Beutin

Phenotypic and genotypic characterization of antimicrobial resistance in Escherichia coli O111 isolates
JAC Advance Access published on April 7, 2006
J. Antimicrob. Chemother. 2006 57: 1210-1214; doi:10.1093/jac/dkl127 [Abstract] [Full Text] [PDF] [Request Permissions]  

David Skurnik, Raymond Ruimy, Antoine Andremont, Christine Amorin, Pierre Rouquet, Bertrand Picard, and Erick Denamur

Effect of human vicinity on antimicrobial resistance and integrons in animal faecal Escherichia coli
JAC Advance Access published on March 31, 2006
J. Antimicrob. Chemother. 2006 57: 1215-1219; doi:10.1093/jac/dkl122 [Abstract] [Full Text] [PDF] Supplementary Data [Request Permissions]  

Miren J. Canduela, Lucía Gallego, Elena Sevillano, Cristina Valderrey, Felícitas Calvo, and Julia Pérez

Evolution of multidrug-resistant Acinetobacter baumannii isolates obtained from elderly patients with respiratory tract infections
JAC Advance Access published on April 5, 2006
J. Antimicrob. Chemother. 2006 57: 1220-1222; doi:10.1093/jac/dkl129 [Abstract] [Full Text] [PDF] [Request Permissions]  

Muriel Masi, Jean-Marie Pagès, and Elizabeth Pradel

Production of the cryptic EefABC efflux pump in Enterobacter aerogenes chloramphenicol-resistant mutants
JAC Advance Access published on April 10, 2006
J. Antimicrob. Chemother. 2006 57: 1223-1226; doi:10.1093/jac/dkl139 [Abstract] [Full Text] [PDF] [Request Permissions]  

C. K. Hope and M. Wilson

Induction of lethal photosensitization in biofilms using a confocal scanning laser as the excitation source
JAC Advance Access published on March 20, 2006
J. Antimicrob. Chemother. 2006 57: 1227-1230; doi:10.1093/jac/dkl096 [Abstract] [Full Text] [PDF] Supplementary Data [Request Permissions]  

Yaya Rukayadi, Dongeun Yong, and Jae-Kwan Hwang

In vitro anticandidal activity of xanthorrhizol isolated from Curcuma xanthorrhiza Roxb
JAC Advance Access published on April 14, 2006
J. Antimicrob. Chemother. 2006 57: 1231-1234; doi:10.1093/jac/dkl132 [Abstract] [Full Text] [PDF] [Request Permissions]  

L. Joseph Wheat, Patricia Connolly, Melinda Smedema, Michelle Durkin, Edward Brizendine, Paul Mann, Reena Patel, Paul M. McNicholas, and Mitchell Goldman

Activity of newer triazoles against Histoplasma capsulatum from patients with AIDS who failed fluconazole
JAC Advance Access published on April 20, 2006
J. Antimicrob. Chemother. 2006 57: 1235-1239; doi:10.1093/jac/dkl133 [Abstract] [Full Text] [PDF] [Request Permissions]  

Michael D. Green, Bernard Beall, Mario J. Marcon, Coburn H. Allen, John S. Bradley, Barry Dashefsky, Janet R. Gilsdorf, Gordon E. Schutze, Clay Smith, Emmanuel B. Walter, Judith M. Martin, Kathryn M. Edwards, Karen A. Barbadora, and Ellen R. Wald

Multicentre surveillance of the prevalence and molecular epidemiology of macrolide resistance among pharyngeal isolates of group A streptococci in the USA
JAC Advance Access published on March 23, 2006
J. Antimicrob. Chemother. 2006 57: 1240-1243; doi:10.1093/jac/dkl101 [Abstract] [Full Text] [PDF] [Request Permissions]  

M. Cruciani, G. Liuzzi, A. Chirianni, S. Audagnotto, S. Bonora, A. Di Biagio, A. Sinicco, M. Bassetti, and G. Gatti

Penetration of didanosine in semen of HIV-1-infected men
JAC Advance Access published on March 23, 2006
J. Antimicrob. Chemother. 2006 57: 1244-1247; doi:10.1093/jac/dkl111 [Abstract] [Full Text] [PDF] [Request Permissions]  

Jan G. den Hollander, Cornelis van Arkel, Bart J. Rijnders, Pieternella J. Lugtenburg, Siem de Marie, and Mark-David Levin

Incidence of voriconazole hepatotoxicity during intravenous and oral treatment for invasive fungal infections
JAC Advance Access published on March 23, 2006
J. Antimicrob. Chemother. 2006 57: 1248-1250; doi:10.1093/jac/dkl108 [Abstract] [Full Text] [PDF] [Request Permissions]  

Matthew E. Falagas, Sofia K. Kasiakou, Petros I. Rafailidis, George Zouglakis, and Panayiota Morfou

Comparison of mortality of patients with Acinetobacter baumannii bacteraemia receiving appropriate and inappropriate empirical therapy
JAC Advance Access published on April 20, 2006
J. Antimicrob. Chemother. 2006 57: 1251-1254; doi:10.1093/jac/dkl130 [Abstract] [Full Text] [PDF] [Request Permissions]  

Correspondence:

Larry M. Baddour, James M. Steckelberg, and Walter R. Wilson

Comment on: The role of aminoglycosides in combination with a ß-lactam for the treatment of bacterial endocarditis: a meta-analysis of comparative trials
JAC Advance Access published on March 20, 2006
J. Antimicrob. Chemother. 2006 57: 1255; doi:10.1093/jac/dkl100 [Extract] [Full Text] [PDF] [Request Permissions]  

Matthew E. Falagas, Dimitrios K. Matthaiou, and Ioannis A. Bliziotis

Aminoglycosides in combination with a ß-lactam for the treatment of bacterial endocarditis: authors' response
JAC Advance Access published on April 4, 2006
J. Antimicrob. Chemother. 2006 57: 1255-1256; doi:10.1093/jac/dkl126 [Extract] [Full Text] [PDF] [Request Permissions]  

Hyun-Joo Kim, Min-Jeong Seol, Hee-Soo Park, Dong-Rak Choi, Seung-Kyoo Seong, Hyun-Kil Shin, and Jin-Hwan Kwak

Antimicrobial activity of DW-224a, a new fluoroquinolone, against Streptococcus pneumoniae
JAC Advance Access published on April 7, 2006
J. Antimicrob. Chemother. 2006 57: 1256-1258; doi:10.1093/jac/dkl144 [Extract] [Full Text] [PDF] [Request Permissions]  

Frank M. Aarestrup, Henrik Hasman, Y. Agersø, L. B. Jensen, Solveig Harksen, and Birgitta Svensmark

First description of bla_CTX-M-1-carrying Escherichia coli isolates in Danish primary food production
JAC Advance Access published on April 5, 2006
J. Antimicrob. Chemother. 2006 57: 1258-1259; doi:10.1093/jac/dkl109 [Extract] [Full Text] [PDF] [Request Permissions]  

Yong Hwan Lee, Byungkyu Cho, Il Kwon Bae, Chulhun L. Chang, and Seok Hoon Jeong

Klebsiella pneumoniae strains carrying the chromosomal SHV-11 ß-lactamase gene produce the plasmid-mediated SHV-12 extended-spectrum ß-lactamase more frequently than those carrying the chromosomal SHV-1 ß-lactamase gene
JAC Advance Access published on April 4, 2006
J. Antimicrob. Chemother. 2006 57: 1259-1261; doi:10.1093/jac/dkl115 [Extract] [Full Text] [PDF] [Request Permissions]  

Chunxin Wang, Peiquan Cai, Dong Chang, and Zuhuang Mi

A Pseudomonas aeruginosa isolate producing the GES-5 extended-spectrum ß-lactamase
JAC Advance Access published on April 14, 2006
J. Antimicrob. Chemother. 2006 57: 1261-1262; doi:10.1093/jac/dkl116 [Extract] [Full Text] [PDF] [Request Permissions]  

Philippe R. S. Lagacé-Wiens, Kim A. Nichol, Lindsay E. Nicolle, Mel DeCorby, Melissa McCracken, Michael R. Mulvey, and George G. Zhanel

Treatment of lower urinary tract infection caused by multidrug-resistant extended-spectrum-ß-lactamase-producing Escherichia coli with amoxicillin/clavulanate: case report and characterization of the isolate
JAC Advance Access published on March 24, 2006
J. Antimicrob. Chemother. 2006 57: 1262-1263; doi:10.1093/jac/dkl102 [Extract] [Full Text] [PDF] [Request Permissions]  

Book review:

S. de Silva

Oxford Handbook of Genitourinary Medicine, HIV and AIDS • R. Pattman, M. Snow, P. Handy, K. N. Sankar and B. Elawad, Eds. • Oxford University Press, Oxford, UK, 2005. • ISBN 0-19-852077-8. £24.95, 580 pp. (pocket book)
JAC Advance Access published on April 11, 2006
J. Antimicrob. Chemother. 2006 57: 1264; doi:10.1093/jac/dkl134 [Extract] [Full Text] [PDF] [Request Permissions]  

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