Journal of Antimicrobial Chemotherapy

Leading articles:

Patricia K. Lee, Tara L. Kieffer, Robert F. Siliciano, and Richard E. Nettles

HIV-1 viral load blips are of limited clinical significance
JAC Advance Access published on March 13, 2006
J. Antimicrob. Chemother. 2006 57: 803-805; doi:10.1093/jac/dkl092 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Pablo Barreiro and Vincent Soriano

Suboptimal CD4 gains in HIV-infected patients receiving didanosine plus tenofovir
JAC Advance Access published on March 10, 2006
J. Antimicrob. Chemother. 2006 57: 806-809; doi:10.1093/jac/dkl045 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Flavia B. Lillo and Caterina Uberti-Foppa

Human papillomavirus viral load: a possible marker for cervical disease in HIV-infected women
JAC Advance Access published on March 23, 2006
J. Antimicrob. Chemother. 2006 57: 810-814; doi:10.1093/jac/dkl073 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Vincent Soriano, Pablo Barreiro, and Marina Nuñez

Management of chronic hepatitis B and C in HIV-coinfected patients
JAC Advance Access published on March 23, 2006
J. Antimicrob. Chemother. 2006 57: 815-818; doi:10.1093/jac/dkl068 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Review:

D. W. M. Verhagen, A. C. Vedder, P. Speelman, and J. T. M. van der Meer

Antimicrobial treatment of infective endocarditis caused by viridans streptococci highly susceptible to penicillin: historic overview and future considerations
JAC Advance Access published on March 20, 2006
J. Antimicrob. Chemother. 2006 57: 819-824; doi:10.1093/jac/dkl087 [Abstract] [Full Text] [PDF] [Request Permissions]  

Original articles:

Lina Marcela Aragón, Ferran Navarro, Volker Heiser, Montserrat Garrigó, Montserrat Español, and Pere Coll

Rapid detection of specific gene mutations associated with isoniazid or rifampicin resistance in Mycobacterium tuberculosis clinical isolates using non-fluorescent low-density DNA microarrays
JAC Advance Access published on March 17, 2006
J. Antimicrob. Chemother. 2006 57: 825-831; doi:10.1093/jac/dkl058 [Abstract] [Full Text] [PDF] [Request Permissions]  

Yvonne Agersø, Anders Gorm Pedersen, and Frank Møller Aarestrup

Identification of Tn5397-like and Tn916-like transposons and diversity of the tetracycline resistance gene tet(M) in enterococci from humans, pigs and poultry
JAC Advance Access published on March 24, 2006
J. Antimicrob. Chemother. 2006 57: 832-839; doi:10.1093/jac/dkl069 [Abstract] [Full Text] [PDF] [Request Permissions]  

Hanna E. Sidjabat, Kirsty M. Townsend, Nancy D. Hanson, Jan M. Bell, H. W. Stokes, Kari S. Gobius, Susan M. Moss, and Darren J. Trott

Identification of bla_CMY-7 and associated plasmid-mediated resistance genes in multidrug-resistant Escherichia coli isolated from dogs at a veterinary teaching hospital in Australia
JAC Advance Access published on March 8, 2006
J. Antimicrob. Chemother. 2006 57: 840-848; doi:10.1093/jac/dkl057 [Abstract] [Full Text] [PDF] [Request Permissions]  

Stephanie K. Henderson-Begg, David M. Livermore, and Lucinda M. C. Hall

Effect of subinhibitory concentrations of antibiotics on mutation frequency in Streptococcus pneumoniae
JAC Advance Access published on March 10, 2006
J. Antimicrob. Chemother. 2006 57: 849-854; doi:10.1093/jac/dkl064 [Abstract] [Full Text] [PDF] [Request Permissions]  

Gabrielle Luck de Araujo, Leonardo Rocchetto Coelho, Camila Barbosa de Carvalho, Rafael Muniz Maciel, Amada Zambrana Coronado, Ronaldo Rozenbaum, Bernadete Teixeira Ferreira-Carvalho, Agnes Marie Sá Figueiredo, and Lenise Arneiro Teixeira

Commensal isolates of methicillin-resistant Staphylococcus epidermidis are also well equipped to produce biofilm on polystyrene surfaces
JAC Advance Access published on March 21, 2006
J. Antimicrob. Chemother. 2006 57: 855-864; doi:10.1093/jac/dkl071 [Abstract] [Full Text] [PDF] [Request Permissions]  

Avshalom Tam, Moshe Shemesh, Uri Wormser, Amnon Sintov, and Doron Steinberg

Effect of different iodine formulations on the expression and activity of Streptococcus mutans glucosyltransferase and fructosyltransferase in biofilm and planktonic environments
JAC Advance Access published on March 20, 2006
J. Antimicrob. Chemother. 2006 57: 865-871; doi:10.1093/jac/dkl085 [Abstract] [Full Text] [PDF] [Request Permissions]  

Osnat Feuerstein, Daniel Moreinos, and Doron Steinberg

Synergic antibacterial effect between visible light and hydrogen peroxide on Streptococcus mutans
JAC Advance Access published on March 13, 2006
J. Antimicrob. Chemother. 2006 57: 872-876; doi:10.1093/jac/dkl070 [Abstract] [Full Text] [PDF] [Request Permissions]  

Belén López-García, Phillip H. A. Lee, and Richard L. Gallo

Expression and potential function of cathelicidin antimicrobial peptides in dermatophytosis and tinea versicolor
JAC Advance Access published on March 23, 2006
J. Antimicrob. Chemother. 2006 57: 877-882; doi:10.1093/jac/dkl078 [Abstract] [Full Text] [PDF] [Request Permissions]  

Hoang Anh Nguyen, Jean Grellet, Delphine Paillard, Véronique Dubois, Claudine Quentin, and Marie-Claude Saux

Factors influencing the intracellular activity of fluoroquinolones: a study using levofloxacin in a Staphylococcus aureus THP-1 monocyte model
JAC Advance Access published on March 13, 2006
J. Antimicrob. Chemother. 2006 57: 883-890; doi:10.1093/jac/dkl079 [Abstract] [Full Text] [PDF] [Request Permissions]  

Pier Luigi Fiori, Antonella Mattana, Daniele Dessì, Stefania Conti, Walter Magliani, and Luciano Polonelli

In vitro acanthamoebicidal activity of a killer monoclonal antibody and a synthetic peptide
JAC Advance Access published on February 28, 2006
J. Antimicrob. Chemother. 2006 57: 891-898; doi:10.1093/jac/dkl051 [Abstract] [Full Text] [PDF] [Request Permissions]  

Lori L. Burrows, Margareta Stark, Celine Chan, Evgenia Glukhov, Selva Sinnadurai, and Charles M. Deber

Activity of novel non-amphipathic cationic antimicrobial peptides against Candida species
JAC Advance Access published on March 8, 2006
J. Antimicrob. Chemother. 2006 57: 899-907; doi:10.1093/jac/dkl056 [Abstract] [Full Text] [PDF] [Request Permissions]  

Olivier Vandenberg, Kurt Houf, Nicole Douat, Linda Vlaes, Patricia Retore, Jean-Paul Butzler, and Anne Dediste

Antimicrobial susceptibility of clinical isolates of non-jejuni/coli campylobacters and arcobacters from Belgium
JAC Advance Access published on March 13, 2006
J. Antimicrob. Chemother. 2006 57: 908-913; doi:10.1093/jac/dkl080 [Abstract] [Full Text] [PDF] [Request Permissions]  

Amy A. Watters, Ronald N. Jones, Jennifer A. Leeds, Gerald Denys, Helio S. Sader, and Thomas R. Fritsche

Antimicrobial activity of a novel peptide deformylase inhibitor, LBM415, tested against respiratory tract and cutaneous infection pathogens: a global surveillance report (2003–2004)
JAC Advance Access published on March 20, 2006
J. Antimicrob. Chemother. 2006 57: 914-923; doi:10.1093/jac/dkl093 [Abstract] [Full Text] [PDF] [Request Permissions]  

Maria Leticia Zarantonelli, Aude Antignac, Marcelo Lancellotti, Annie Guiyoule, Jean-Michel Alonso, and Muhamed-Kheir Taha

Immunogenicity of meningococcal PBP2 during natural infection and protective activity of anti-PBP2 antibodies against meningococcal bacteraemia in mice
JAC Advance Access published on March 2, 2006
J. Antimicrob. Chemother. 2006 57: 924-930; doi:10.1093/jac/dkl066 [Abstract] [Full Text] [PDF] [Request Permissions]  

Sandra Ribes, Ferran Taberner, Alejandro Domenech, Carmen Cabellos, Fe Tubau, Josefina Liñares, Pedro Fernández Viladrich, and Francesc Gudiol

Evaluation of fosfomycin alone and in combination with ceftriaxone or vancomycin in an experimental model of meningitis caused by two strains of cephalosporin-resistant Streptococcus pneumoniae
JAC Advance Access published on February 28, 2006
J. Antimicrob. Chemother. 2006 57: 931-936; doi:10.1093/jac/dkl047 [Abstract] [Full Text] [PDF] [Request Permissions]  

Evangelos J. Giamarellos-Bourboulis, Vassiliki Tziortzioti, Pantelis Koutoukas, Fotini Baziaka, Maria Raftogiannis, Anastasia Antonopoulou, Theodoros Adamis, Labros Sabracos, and Helen Giamarellou

Clarithromycin is an effective immunomodulator in experimental pyelonephritis caused by pan-resistant Klebsiella pneumoniae
JAC Advance Access published on March 20, 2006
J. Antimicrob. Chemother. 2006 57: 937-944; doi:10.1093/jac/dkl084 [Abstract] [Full Text] [PDF] [Request Permissions]  

Anders Helldén, Jan Lycke, Tatiana Vander, Jan-Olof Svensson, Ingegerd Odar-Cederlöf, and Lars Ståhle

The aciclovir metabolite CMMG is detectable in the CSF of subjects with neuropsychiatric symptoms during aciclovir and valaciclovir treatment
JAC Advance Access published on March 15, 2006
J. Antimicrob. Chemother. 2006 57: 945-949; doi:10.1093/jac/dkl067 [Abstract] [Full Text] [PDF] [Request Permissions]  

L. Malincarne, M. Ghebregzabher, M. V. Moretti, A. M. Egidi, B. Canovari, G. Tavolieri, D. Francisci, G. Cerulli, and F. Baldelli

Penetration of moxifloxacin into bone in patients undergoing total knee arthroplasty
JAC Advance Access published on March 21, 2006
J. Antimicrob. Chemother. 2006 57: 950-954; doi:10.1093/jac/dkl091 [Abstract] [Full Text] [PDF] [Request Permissions]  

Sita Nys, T. van Merode, A. I. M. Bartelds, and E. E. Stobberingh

Urinary tract infections in general practice patients: diagnostic tests versus bacteriological culture
JAC Advance Access published on March 22, 2006
J. Antimicrob. Chemother. 2006 57: 955-958; doi:10.1093/jac/dkl082 [Abstract] [Full Text] [PDF] [Request Permissions]  

Antimicrobial practice:

M. H. Ali, P. Kalima, and S. R. J. Maxwell

Failure to implement hospital antimicrobial prescribing guidelines: a comparison of two UK academic centres
JAC Advance Access published on March 10, 2006
J. Antimicrob. Chemother. 2006 57: 959-962; doi:10.1093/jac/dkl076 [Abstract] [Full Text] [PDF] [Request Permissions]  

H. M. Ziglam, D. Morales, K. Webb, and D. Nathwani

Knowledge about sepsis among training-grade doctors
JAC Advance Access published on March 13, 2006
J. Antimicrob. Chemother. 2006 57: 963-965; doi:10.1093/jac/dkl042 [Abstract] [Full Text] [PDF] [Request Permissions]  

Brief reports:

Petra Lüthje and Stefan Schwarz

Antimicrobial resistance of coagulase-negative staphylococci from bovine subclinical mastitis with particular reference to macrolide–lincosamide resistance phenotypes and genotypes
JAC Advance Access published on March 8, 2006
J. Antimicrob. Chemother. 2006 57: 966-969; doi:10.1093/jac/dkl061 [Abstract] [Full Text] [PDF] [Request Permissions]  

Stefanie Pannek, Paul G. Higgins, Petra Steinke, Daniel Jonas, Murat Akova, Jürgen A. Bohnert, Harald Seifert, and Winfried V. Kern

Multidrug efflux inhibition in Acinetobacter baumannii: comparison between 1-(1-naphthylmethyl)-piperazine and phenyl-arginine-ß-naphthylamide
JAC Advance Access published on March 10, 2006
J. Antimicrob. Chemother. 2006 57: 970-974; doi:10.1093/jac/dkl081 [Abstract] [Full Text] [PDF] [Request Permissions]  

Giuseppe Celenza, Cristina Pellegrini, Marisa Caccamo, Bernardetta Segatore, Gianfranco Amicosante, and Mariagrazia Perilli

Spread of bla_CTX-M-type and bla_PER-2 ß-lactamase genes in clinical isolates from Bolivian hospitals
JAC Advance Access published on March 1, 2006
J. Antimicrob. Chemother. 2006 57: 975-978; doi:10.1093/jac/dkl055 [Abstract] [Full Text] [PDF] [Request Permissions]  

Maria Bagattini, Valeria Crivaro, Anna Di Popolo, Fabrizio Gentile, Alda Scarcella, Maria Triassi, Paolo Villari, and Raffaele Zarrilli

Molecular epidemiology of extended-spectrum ß-lactamase-producing Klebsiella pneumoniae in a neonatal intensive care unit
JAC Advance Access published on March 10, 2006
J. Antimicrob. Chemother. 2006 57: 979-982; doi:10.1093/jac/dkl077 [Abstract] [Full Text] [PDF] [Request Permissions]  

Rosa del Campo, Fabio Cafini, María Isabel Morosini, Asunción Fenoll, Josefina Liñares, Luis Alou, David Sevillano, Rafael Cantón, José Prieto, and Fernando Baquero on behalf of the Spanish Pneumococcal Network (G3/103)

Combinations of PBPs and MurM protein variants in early and contemporary high-level penicillin-resistant Streptococcus pneumoniae isolates in Spain
JAC Advance Access published on March 13, 2006
J. Antimicrob. Chemother. 2006 57: 983-986; doi:10.1093/jac/dkl083 [Abstract] [Full Text] [PDF] [Request Permissions]  

H. Syre, H. Valvatne, P. Sandven, and H. M. S. Grewal

Evaluation of the nitrate-based colorimetric method for testing the susceptibility of Mycobacterium tuberculosis to streptomycin and ethambutol in liquid cultures
JAC Advance Access published on March 8, 2006
J. Antimicrob. Chemother. 2006 57: 987-991; doi:10.1093/jac/dkl054 [Abstract] [Full Text] [PDF] [Request Permissions]  

Sally A. Roberts, Keith P. Shore, Susan D. Paviour, David Holland, and Arthur J. Morris

Antimicrobial susceptibility of anaerobic bacteria in New Zealand: 1999–2003
JAC Advance Access published on February 28, 2006
J. Antimicrob. Chemother. 2006 57: 992-998; doi:10.1093/jac/dkl052 [Abstract] [Full Text] [PDF] [Request Permissions]  

Philip D. Lister, Daniel J. Wolter, Paul A. Wickman, and Mark D. Reisbig

Levofloxacin/imipenem prevents the emergence of high-level resistance among Pseudomonas aeruginosa strains already lacking susceptibility to one or both drugs
JAC Advance Access published on March 2, 2006
J. Antimicrob. Chemother. 2006 57: 999-1003; doi:10.1093/jac/dkl063 [Abstract] [Full Text] [PDF] [Request Permissions]  

Yuki Asano-Mori, Yoshinobu Kanda, Kumi Oshima, Takuro Watanabe, Eriko Shoda, Toru Motokura, Mineo Kurokawa, and Shigeru Chiba

Pharmacokinetics of ganciclovir in haematopoietic stem cell transplantation recipients with or without renal impairment
JAC Advance Access published on March 21, 2006
J. Antimicrob. Chemother. 2006 57: 1004-1007; doi:10.1093/jac/dkl089 [Abstract] [Full Text] [PDF] [Request Permissions]  

Correspondence:

S. McNicholas, A. Barber, G. Corbett-Feeney, and M. Cormican

Linezolid audit: similarities and contrasts with published experience
JAC Advance Access published on March 20, 2006
J. Antimicrob. Chemother. 2006 57: 1008-1009; doi:10.1093/jac/dkl090 [Extract] [Full Text] [PDF] [Request Permissions]  

B. Ni Laoi, C. Herra, S. Norris, and B. Crowley

First report of genotypic resistance to adefovir in chronic HBV in the Republic of Ireland
JAC Advance Access published on March 8, 2006
J. Antimicrob. Chemother. 2006 57: 1009-1010; doi:10.1093/jac/dkl065 [Extract] [Full Text] [PDF] [Request Permissions]  

S. Ballesta, M. C. Conejo, I. García, J. M. Rodríguez-Martínez, C. Velasco, and A. Pascual

Survival and resistance to imipenem of Pseudomonas aeruginosa on latex gloves
JAC Advance Access published on March 10, 2006
J. Antimicrob. Chemother. 2006 57: 1010-1012; doi:10.1093/jac/dkl072 [Extract] [Full Text] [PDF] [Request Permissions]  

David M. Livermore, Russell Hope, Elizabeth J. Fagan, Marina Warner, Neil Woodford, and Nicola Potz

Activity of temocillin against prevalent ESBL- and AmpC-producing Enterobacteriaceae from south-east England
JAC Advance Access published on March 10, 2006
J. Antimicrob. Chemother. 2006 57: 1012-1014; doi:10.1093/jac/dkl043 [Extract] [Full Text] [PDF] [Request Permissions]  

Nuno Mendonça, Deolinda Louro, Ana Paula Castro, José Diogo, and Manuela Caniça

CTX-M-15, OXA-30 and TEM-1-producing Escherichia coli in two Portuguese regions
JAC Advance Access published on March 10, 2006
J. Antimicrob. Chemother. 2006 57: 1014-1016; doi:10.1093/jac/dkl062 [Extract] [Full Text] [PDF] [Request Permissions]  

Juan A. Pineda, Rosario Palacios, Antonio Rivero, Laila Abdel-kader, Manuel Márquez, Pilar Cano, José A. Mira, Julián Torre-Cisneros, Fernando Lozano, and Jesús Santos

Low incidence of severe liver toxicity in patients receiving antiretroviral combinations including atazanavir
JAC Advance Access published on March 23, 2006
J. Antimicrob. Chemother. 2006 57: 1016-1017; doi:10.1093/jac/dkl074 [Extract] [Full Text] [PDF] [Request Permissions]  

Emily E. Han, Paul M. Beringer, Pål Falck, Stan Louie, Purush Rao, Bertrand Shapiro, and Mark Gill

Pilot study of continuous infusion cefepime in adult patients with cystic fibrosis
JAC Advance Access published on March 13, 2006
J. Antimicrob. Chemother. 2006 57: 1017-1019; doi:10.1093/jac/dkl053 [Extract] [Full Text] [PDF] [Request Permissions]  

Miguel G. Madariaga

Non-adherence to infectious disease consultations: are surgeons to blame?
JAC Advance Access published on March 10, 2006
J. Antimicrob. Chemother. 2006 57: 1019-1020; doi:10.1093/jac/dkl075 [Extract] [Full Text] [PDF] [Request Permissions]  

Book review:

Kate Cuschieri

Papillomavirus Research—From Natural History to Vaccines and Beyond • M. Saveria Campo, Ed. • Caister Academic Press, UK, 2006. • ISBN 1-904455-04-2. £150, 424 pp.
JAC Advance Access published on March 15, 2006
J. Antimicrob. Chemother. 2006 57: 1021; doi:10.1093/jac/dkl086 [Extract] [Full Text] [PDF] [Request Permissions]  

Errata:

Silvano Esposito, Silvana Noviello, Gioacchino D'Errico, Gaetano Motta, Desiderio Passali, Claudia Aimoni, Stefano Pelucchi, Stefania Fallani, Maria Iris Cassetta, Teresita Mazzei, and Andrea Novelli

Concentration of moxifloxacin in plasma and tonsillar tissue after multiple administration in adult patients
JAC Advance Access published on March 29, 2006
J. Antimicrob. Chemother. 2006 57: 1022; doi:10.1093/jac/dkl119 [Extract] [Full Text] [PDF] [Request Permissions]  

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