Journal of Antimicrobial Chemotherapy

Leading articles:

R. Scott McClelland and Jared M. Baeten

Reducing HIV-1 transmission through prevention strategies targeting HIV-1-seropositive individuals
JAC Advance Access published on December 6, 2005
J. Antimicrob. Chemother. 2006 57: 163-166; doi:10.1093/jac/dki433 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Samuel A. Shelburne, Martin Montes, and Richard J. Hamill

Immune reconstitution inflammatory syndrome: more answers, more questions
JAC Advance Access published on December 14, 2005
J. Antimicrob. Chemother. 2006 57: 167-170; doi:10.1093/jac/dki444 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Meeting report:

Colin W. E. Drummond

Resistance is futile—a conference to promote the rational use of antimicrobials in acute hospitals
JAC Advance Access published on November 30, 2005
J. Antimicrob. Chemother. 2006 57: 171-175; doi:10.1093/jac/dki434 [Abstract] [Full Text] [PDF] [Request Permissions]  

Systematic review:

Mical Paul, Dafna Yahav, Abigail Fraser, and Leonard Leibovici

Empirical antibiotic monotherapy for febrile neutropenia: systematic review and meta-analysis of randomized controlled trials
JAC Advance Access published on December 12, 2005
J. Antimicrob. Chemother. 2006 57: 176-189; doi:10.1093/jac/dki448 [Abstract] [Full Text] [PDF] Supplementary Data [Request Permissions]  

Original articles:

J. D. Tankson, P. J. Fedorka-Cray, C. R. Jackson, and M. Headrick

Genetic relatedness of a rarely isolated Salmonella: Salmonella enterica serotype Niakhar from NARMS animal isolates
JAC Advance Access published on December 13, 2005
J. Antimicrob. Chemother. 2006 57: 190-198; doi:10.1093/jac/dki439 [Abstract] [Full Text] [PDF] [Request Permissions]  

Virginia C. Gould, Aki Okazaki, and Matthew B. Avison

ß-Lactam resistance and ß-lactamase expression in clinical Stenotrophomonas maltophilia isolates having defined phylogenetic relationships
JAC Advance Access published on December 13, 2005
J. Antimicrob. Chemother. 2006 57: 199-203; doi:10.1093/jac/dki453 [Abstract] [Full Text] [PDF] [Request Permissions]  

Eva Moreno, Guillem Prats, Montserrat Sabaté, Teresa Pérez, James R. Johnson, and Antonia Andreu

Quinolone, fluoroquinolone and trimethoprim/sulfamethoxazole resistance in relation to virulence determinants and phylogenetic background among uropathogenic Escherichia coli
JAC Advance Access published on January 3, 2006
J. Antimicrob. Chemother. 2006 57: 204-211; doi:10.1093/jac/dki468 [Abstract] [Full Text] [PDF] [Request Permissions]  

József Sóki, Micaela Gal, Jon S. Brazier, Vincent O. Rotimi, Edit Urbán, Elisabeth Nagy, and Brian I. Duerden

Molecular investigation of genetic elements contributing to metronidazole resistance in Bacteroides strains
JAC Advance Access published on December 7, 2005
J. Antimicrob. Chemother. 2006 57: 212-220; doi:10.1093/jac/dki443 [Abstract] [Full Text] [PDF] [Request Permissions]  

Cosme Alvarado-Esquivel, Manuela de la Ascensión Carrera-Gracia, Carlos Jesús Conde-González, Luis Juárez-Figueroa, Lilia Ruiz-Maya, Sergio Aguilar-Benavides, Alejandro Torres-Valenzuela, and Erwin Sablon

Genotypic resistance to lamivudine among hepatitis B virus isolates in Mexico
JAC Advance Access published on December 22, 2005
J. Antimicrob. Chemother. 2006 57: 221-223; doi:10.1093/jac/dki457 [Abstract] [Full Text] [PDF] [Request Permissions]  

Fabio Cafini, Rosa del Campo, Luis Alou, David Sevillano, María Isabel Morosini, Fernando Baquero, and José Prieto on behalf of the Spanish Pneumococcal Network (G03/103)

Alterations of the penicillin-binding proteins and murM alleles of clinical Streptococcus pneumoniae isolates with high-level resistance to amoxicillin in Spain
JAC Advance Access published on December 20, 2005
J. Antimicrob. Chemother. 2006 57: 224-229; doi:10.1093/jac/dki442 [Abstract] [Full Text] [PDF] [Request Permissions]  

Itamar Shalit, Drora Halperin, Debby Haite, Avital Levitov, Jacob Romano, Nir Osherov, and Ina Fabian

Anti-inflammatory effects of moxifloxacin on IL-8, IL-1ß and TNF- secretion and NFB and MAP-kinase activation in human monocytes stimulated with Aspergillus fumigatus
JAC Advance Access published on December 13, 2005
J. Antimicrob. Chemother. 2006 57: 230-235; doi:10.1093/jac/dki441 [Abstract] [Full Text] [PDF] [Request Permissions]  

Ekatherina Charvalos, Manolis N. Tzatzarakis, Françoise Van Bambeke, Paul M. Tulkens, Aristidis M. Tsatsakis, George N. Tzanakakis, and Marie-Paule Mingeot-Leclercq

Water-soluble amphotericin B–polyvinylpyrrolidone complexes with maintained antifungal activity against Candida spp. and Aspergillus spp. and reduced haemolytic and cytotoxic effects
JAC Advance Access published on December 16, 2005
J. Antimicrob. Chemother. 2006 57: 236-244; doi:10.1093/jac/dki455 [Abstract] [Full Text] [PDF] [Request Permissions]  

Estelle André, Lionel Bastide, Sylvie Michaux-Charachon, Anne Gouby, Philippe Villain-Guillot, Jaqueline Latouche, Aurélie Bouchet, Maxime Gualtiéri, and Jean-Paul Leonetti

Novel synthetic molecules targeting the bacterial RNA polymerase assembly
JAC Advance Access published on December 22, 2005
J. Antimicrob. Chemother. 2006 57: 245-251; doi:10.1093/jac/dki426 [Abstract] [Full Text] [PDF] [Request Permissions]  

Santiago Ramón-García, Carlos Martín, José A. Aínsa, and Edda De Rossi

Characterization of tetracycline resistance mediated by the efflux pump Tap from Mycobacterium fortuitum
JAC Advance Access published on December 22, 2005
J. Antimicrob. Chemother. 2006 57: 252-259; doi:10.1093/jac/dki436 [Abstract] [Full Text] [PDF] [Request Permissions]  

W. Baranska-Rybak, A. Sonesson, R. Nowicki, and A. Schmidtchen

Glycosaminoglycans inhibit the antibacterial activity of LL-37 in biological fluids
JAC Advance Access published on December 30, 2005
J. Antimicrob. Chemother. 2006 57: 260-265; doi:10.1093/jac/dki460 [Abstract] [Full Text] [PDF] [Request Permissions]  

G. Ll. Jones, C. T. Muller, M. O'Reilly, and D. J. Stickler

Effect of triclosan on the development of bacterial biofilms by urinary tract pathogens on urinary catheters
JAC Advance Access published on December 9, 2005
J. Antimicrob. Chemother. 2006 57: 266-272; doi:10.1093/jac/dki447 [Abstract] [Full Text] [PDF] [Request Permissions]  

C. Blaha, M. Duchêne, H. Aspöck, and J. Walochnik

In vitro activity of hexadecylphosphocholine (miltefosine) against metronidazole-resistant and -susceptible strains of Trichomonas vaginalis
JAC Advance Access published on December 12, 2005
J. Antimicrob. Chemother. 2006 57: 273-278; doi:10.1093/jac/dki417 [Abstract] [Full Text] [PDF] [Request Permissions]  

Ronald N. Jones, James E. Ross, Thomas R. Fritsche, and Helio S. Sader

Oxazolidinone susceptibility patterns in 2004: report from the Zyvox® Annual Appraisal of Potency and Spectrum (ZAAPS) Program assessing isolates from 16 nations
JAC Advance Access published on December 2, 2005
J. Antimicrob. Chemother. 2006 57: 279-287; doi:10.1093/jac/dki437 [Abstract] [Full Text] [PDF] [Request Permissions]  

Russell E. Lewis, Nathan P. Wiederhold, Randall A. Prince, and Dimitrios P. Kontoyiannis

In vitro pharmacodynamics of rapid versus continuous infusion of amphotericin B deoxycholate against Candida species in the presence of human serum albumin
JAC Advance Access published on December 30, 2005
J. Antimicrob. Chemother. 2006 57: 288-293; doi:10.1093/jac/dki467 [Abstract] [Full Text] [PDF] [Request Permissions]  

Lian-Chen Wang, Shih-Ming Jung, Chien-Chuan Chen, Ho-Fai Wong, Dinah-Pingni Wan, and Yung-Liang Wan

Pathological changes in the brains of rabbits experimentally infected with Angiostrongylus cantonensis after albendazole treatment: histopathological and magnetic resonance imaging studies
JAC Advance Access published on November 30, 2005
J. Antimicrob. Chemother. 2006 57: 294-300; doi:10.1093/jac/dki430 [Abstract] [Full Text] [PDF] [Request Permissions]  

Mark S. Rouse, Kerryl E. Piper, Melissa Jacobson, David J. Jacofsky, James M. Steckelberg, and Robin Patel

Daptomycin treatment of Staphylococcus aureus experimental chronic osteomyelitis
JAC Advance Access published on December 16, 2005
J. Antimicrob. Chemother. 2006 57: 301-305; doi:10.1093/jac/dki435 [Abstract] [Full Text] [PDF] [Request Permissions]  

F. Ratjen, E. Rietschel, D. Kasel, R. Schwiertz, K. Starke, H. Beier, S. van Koningsbruggen, and H. Grasemann

Pharmacokinetics of inhaled colistin in patients with cystic fibrosis
JAC Advance Access published on January 5, 2006
J. Antimicrob. Chemother. 2006 57: 306-311; doi:10.1093/jac/dki461 [Abstract] [Full Text] [PDF] [Request Permissions]  

M. Wittau, E. Wagner, V. Kaever, T. Koal, D. Henne-Bruns, and R. Isenmann

Intraabdominal tissue concentration of ertapenem
JAC Advance Access published on January 5, 2006
J. Antimicrob. Chemother. 2006 57: 312-316; doi:10.1093/jac/dki459 [Abstract] [Full Text] [PDF] [Request Permissions]  

Axel Glasmacher, Oliver Cornely, Andrew J. Ullmann, Ulrich Wedding, Heinrich Bodenstein, Hannes Wandt, Christian Boewer, Rita Pasold, Hans-Heinrich Wolf, Mathias Hänel, Gottfried Dölken, Christian Junghanss, Reinhard Andreesen, and Hartmut Bertz on behalf of the Itraconazole Research Group of Germany

An open-label randomized trial comparing itraconazole oral solution with fluconazole oral solution for primary prophylaxis of fungal infections in patients with haematological malignancy and profound neutropenia
JAC Advance Access published on December 8, 2005
J. Antimicrob. Chemother. 2006 57: 317-325; doi:10.1093/jac/dki440 [Abstract] [Full Text] [PDF] [Request Permissions]  

Antimicrobial practice:

Dag Berild, Atefeh Mohseni, Lien My Diep, Mogens Jensenius, and Signe Holta Ringertz

Adjustment of antibiotic treatment according to the results of blood cultures leads to decreased antibiotic use and costs
JAC Advance Access published on December 30, 2005
J. Antimicrob. Chemother. 2006 57: 326-330; doi:10.1093/jac/dki463 [Abstract] [Full Text] [PDF] [Request Permissions]  

Brief reports:

Ana Budimir, Ruud H. Deurenberg, Vanda Plecko, Cornelis Vink, Smilja Kalenic, and Ellen E. Stobberingh

Molecular characterization of methicillin-resistant Staphylococcus aureus bloodstream isolates from Croatia
JAC Advance Access published on December 9, 2005
J. Antimicrob. Chemother. 2006 57: 331-334; doi:10.1093/jac/dki452 [Abstract] [Full Text] [PDF] [Request Permissions]  

J. C. N. Shackelford, G. W. Hanlon, and J.-Y. Maillard

Use of a new alginate film test to study the bactericidal efficacy of the high-level disinfectant ortho-phthalaldehyde
JAC Advance Access published on December 6, 2005
J. Antimicrob. Chemother. 2006 57: 335-338; doi:10.1093/jac/dki432 [Abstract] [Full Text] [PDF] [Request Permissions]  

Winfried V. Kern, Petra Steinke, Anja Schumacher, Sabine Schuster, Heike von Baum, and Jürgen A. Bohnert

Effect of 1-(1-naphthylmethyl)-piperazine, a novel putative efflux pump inhibitor, on antimicrobial drug susceptibility in clinical isolates of Escherichia coli
JAC Advance Access published on December 14, 2005
J. Antimicrob. Chemother. 2006 57: 339-343; doi:10.1093/jac/dki445 [Abstract] [Full Text] [PDF] [Request Permissions]  

Anja Schumacher, Petra Steinke, Jürgen A. Bohnert, Murat Akova, Daniel Jonas, and Winfried V. Kern

Effect of 1-(1-naphthylmethyl)-piperazine, a novel putative efflux pump inhibitor, on antimicrobial drug susceptibility in clinical isolates of Enterobacteriaceae other than Escherichia coli
JAC Advance Access published on December 14, 2005
J. Antimicrob. Chemother. 2006 57: 344-348; doi:10.1093/jac/dki446 [Abstract] [Full Text] [PDF] [Request Permissions]  

Tahseen H. Nasti, Masood A. Khan, and M. Owais

Enhanced efficacy of pH-sensitive nystatin liposomes against Cryptococcus neoformans in murine model
JAC Advance Access published on December 20, 2005
J. Antimicrob. Chemother. 2006 57: 349-352; doi:10.1093/jac/dki454 [Abstract] [Full Text] [PDF] [Request Permissions]  

A. Baishanbo, G. Gargala, C. Duclos, A. François, J.-F. Rossignol, J. J. Ballet, and L. Favennec

Efficacy of nitazoxanide and paromomycin in biliary tract cryptosporidiosis in an immunosuppressed gerbil model
JAC Advance Access published on December 16, 2005
J. Antimicrob. Chemother. 2006 57: 353-355; doi:10.1093/jac/dki456 [Abstract] [Full Text] [PDF] [Request Permissions]  

E. O'Neill, H. Humphreys, J. Phillips, and E. G. Smyth

Third-generation cephalosporin resistance among Gram-negative bacilli causing meningitis in neurosurgical patients: significant challenges in ensuring effective antibiotic therapy
JAC Advance Access published on December 20, 2005
J. Antimicrob. Chemother. 2006 57: 356-359; doi:10.1093/jac/dki462 [Abstract] [Full Text] [PDF] [Request Permissions]  

Francesco G. De Rosa, Olivia Bargiacchi, Sabrina Audagnotto, Silvia Garazzino, Giuseppe Cariti, Riccardo Raiteri, and Giovanni Di Perri

Dose-dependent and genotype-independent sustained virological response of a 12 week pegylated interferon alpha-2b treatment for acute hepatitis C
JAC Advance Access published on January 5, 2006
J. Antimicrob. Chemother. 2006 57: 360-363; doi:10.1093/jac/dki458 [Abstract] [Full Text] [PDF] [Request Permissions]  

Correspondence:

J. M. Ling and Y. Jin

Evaluation of six fluoroquinolones for their capabilities in restricting the selection of resistant salmonellae
JAC Advance Access published on December 20, 2005
J. Antimicrob. Chemother. 2006 57: 364-365; doi:10.1093/jac/dki465 [Extract] [Full Text] [PDF] [Request Permissions]  

P. L. Ho, Gannon C. Mak, Cindy W. S. Tse, K. H. Chow, and Chris H. Y. Cheung

Invasive Haemophilus influenzae isolates with decreased levofloxacin susceptibility in Hong Kong
JAC Advance Access published on December 30, 2005
J. Antimicrob. Chemother. 2006 57: 366; doi:10.1093/jac/dki466 [Extract] [Full Text] [PDF] [Request Permissions]  

K. Thomas, M. J. Weinbren, M. Warner, N. Woodford, and D. Livermore

Activity of mecillinam against ESBL producers in vitro
JAC Advance Access published on December 14, 2005
J. Antimicrob. Chemother. 2006 57: 367-368; doi:10.1093/jac/dki451 [Extract] [Full Text] [PDF] [Request Permissions]  

Véronique Dubois, Corinne Arpin, Laure Coulange, Catherine André, Patrick Noury, and Claudine Quentin

TEM-21 extended-spectrum ß-lactamase in a clinical isolate of Alcaligenes faecalis from a nursing home
JAC Advance Access published on December 12, 2005
J. Antimicrob. Chemother. 2006 57: 368-369; doi:10.1093/jac/dki450 [Extract] [Full Text] [PDF] [Request Permissions]  

Kenichi Kaneko, Yoshinori Sato, Shu-ko Tokunaga, Sho-ko Tamaki, Ryoichi Okamoto, and Matsuhisa Inoue

AmpC ß-lactamase-mediated cefpodoxime-resistant Escherichia coli isolated from faecal samples of healthy volunteers
JAC Advance Access published on December 7, 2005
J. Antimicrob. Chemother. 2006 57: 369-371; doi:10.1093/jac/dki438 [Extract] [Full Text] [PDF] [Request Permissions]  

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