Journal of Antimicrobial Chemotherapy

Leading articles:

Susan Brown and Sebastian Amyes

OXA ß-lactamases in Acinetobacter: the story so far
JAC Advance Access published on December 6, 2005
J. Antimicrob. Chemother. 2006 57: 1-3; doi:10.1093/jac/dki425 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Sophie Grabar, Laurence Weiss, and Dominique Costagliola

HIV infection in older patients in the HAART era
JAC Advance Access published on November 11, 2005
J. Antimicrob. Chemother. 2006 57: 4-7; doi:10.1093/jac/dki411 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Robert G. Gish

Treating HCV with ribavirin analogues and ribavirin-like molecules
JAC Advance Access published on November 17, 2005
J. Antimicrob. Chemother. 2006 57: 8-13; doi:10.1093/jac/dki405 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

C. Eckert, V. Gautier, and G. Arlet

DNA sequence analysis of the genetic environment of various bla_CTX-M genes
JAC Advance Access published on November 16, 2005
J. Antimicrob. Chemother. 2006 57: 14-23; doi:10.1093/jac/dki398 [Abstract] [Full Text] [PDF] [Request Permissions]  

Olusegun O. Soge, Anne Marie Queenan, Kayode K. Ojo, Bolanle A. Adeniyi, and Marilyn C. Roberts

CTX-M-15 extended-spectrum ß-lactamase from Nigerian Klebsiella pneumoniae
JAC Advance Access published on November 30, 2005
J. Antimicrob. Chemother. 2006 57: 24-30; doi:10.1093/jac/dki429 [Abstract] [Full Text] [PDF] [Request Permissions]  

T. L. Poole, T. R. Callaway, K. M. Bischoff, C. E. Warnes, and D. J. Nisbet

Macrolide inactivation gene cluster mphA-mrx-mphR adjacent to a class 1 integron in Aeromonas hydrophila isolated from a diarrhoeic pig in Oklahoma
JAC Advance Access published on December 8, 2005
J. Antimicrob. Chemother. 2006 57: 31-38; doi:10.1093/jac/dki421 [Abstract] [Full Text] [PDF] [Request Permissions]  

A. Herrero, M. R. Rodicio, M. A. González-Hevia, and M. C. Mendoza

Molecular epidemiology of emergent multidrug-resistant Salmonella enterica serotype Typhimurium strains carrying the virulence resistance plasmid pUO-StVR2
JAC Advance Access published on November 12, 2005
J. Antimicrob. Chemother. 2006 57: 39-45; doi:10.1093/jac/dki400 [Abstract] [Full Text] [PDF] [Request Permissions]  

Jostein Bjorland, Terje Steinum, Marianne Sunde, Steinar Waage, Ståle Sviland, Hanne Oppegaard, and Even Heir

Deletion of pT181-like sequence in an smr-encoding mosaic plasmid harboured by a persistent bovine Staphylococcus warneri strain
JAC Advance Access published on November 12, 2005
J. Antimicrob. Chemother. 2006 57: 46-51; doi:10.1093/jac/dki407 [Abstract] [Full Text] [PDF] [Request Permissions]  

Masato Akiba, Jun Lin, Yi-Wen Barton, and Qijing Zhang

Interaction of CmeABC and CmeDEF in conferring antimicrobial resistance and maintaining cell viability in Campylobacter jejuni
JAC Advance Access published on November 22, 2005
J. Antimicrob. Chemother. 2006 57: 52-60; doi:10.1093/jac/dki419 [Abstract] [Full Text] [PDF] [Request Permissions]  

Dominic Granger, Geneviève Boily-Larouche, Pierre Turgeon, Karl Weiss, and Michel Roger

Molecular characteristics of pbp1a and pbp2b in clinical Streptococcus pneumoniae isolates in Quebec, Canada
JAC Advance Access published on November 9, 2005
J. Antimicrob. Chemother. 2006 57: 61-70; doi:10.1093/jac/dki401 [Abstract] [Full Text] [PDF] [Request Permissions]  

Patrizia Posteraro, Giovanna Branca, Maurizio Sanguinetti, Stefania Ranno, Giovanni Cammarota, Siavash Rahimi, Mario De Carlo, Brunella Posteraro, and Giovanni Fadda

Rapid detection of clarithromycin resistance in Helicobacter pylori using a PCR-based denaturing HPLC assay
JAC Advance Access published on November 11, 2005
J. Antimicrob. Chemother. 2006 57: 71-78; doi:10.1093/jac/dki406 [Abstract] [Full Text] [PDF] [Request Permissions]  

M. C. Cholo, H. I. Boshoff, H. C. Steel, R. Cockeran, N. M. Matlola, K. J. Downing, V. Mizrahi, and R. Anderson

Effects of clofazimine on potassium uptake by a Trk-deletion mutant of Mycobacterium tuberculosis
JAC Advance Access published on November 12, 2005
J. Antimicrob. Chemother. 2006 57: 79-84; doi:10.1093/jac/dki409 [Abstract] [Full Text] [PDF] [Request Permissions]  

Shanshan Cai, Katsumasa Sato, Toshiaki Shimizu, Seiko Yamabe, Miho Hiraki, Chiaki Sano, and Haruaki Tomioka

Antimicrobial activity of picolinic acid against extracellular and intracellular Mycobacterium avium complex and its combined activity with clarithromycin, rifampicin and fluoroquinolones
JAC Advance Access published on November 22, 2005
J. Antimicrob. Chemother. 2006 57: 85-93; doi:10.1093/jac/dki418 [Abstract] [Full Text] [PDF] [Request Permissions]  

Toyohiro Tanida, Tetsuro Okamoto, Eisaku Ueta, Tetsuya Yamamoto, and Tokio Osaki

Antimicrobial peptides enhance the candidacidal activity of antifungal drugs by promoting the efflux of ATP from Candida cells
JAC Advance Access published on November 16, 2005
J. Antimicrob. Chemother. 2006 57: 94-103; doi:10.1093/jac/dki402 [Abstract] [Full Text] [PDF] [Request Permissions]  

Benjamin R. D. Short, Miguel A. Vargas, Jonathan C. Thomas, Simon O'Hanlon, and Mark C. Enright

In vitro activity of a novel compound, the metal ion chelating agent AQ⁺, against clinical isolates of Staphylococcus aureus
JAC Advance Access published on November 30, 2005
J. Antimicrob. Chemother. 2006 57: 104-109; doi:10.1093/jac/dki428 [Abstract] [Full Text] [PDF] [Request Permissions]  

Lise Musset, Bruno Pradines, Daniel Parzy, Rémy Durand, Patricia Bigot, and Jacques Le Bras

Apparent absence of atovaquone/proguanil resistance in 477 Plasmodium falciparum isolates from untreated French travellers
JAC Advance Access published on November 30, 2005
J. Antimicrob. Chemother. 2006 57: 110-115; doi:10.1093/jac/dki420 [Abstract] [Full Text] [PDF] [Request Permissions]  

Vanthida Huang and Michael J. Rybak

Evaluation of daptomycin activity against Staphylococcus aureus in an in vitro pharmacodynamic model under normal and simulated impaired renal function
JAC Advance Access published on November 25, 2005
J. Antimicrob. Chemother. 2006 57: 116-121; doi:10.1093/jac/dki422 [Abstract] [Full Text] [PDF] [Request Permissions]  

Katsunori Yanagihara, Miwa Tashiro, Yuichi Fukuda, Hideaki Ohno, Yasuhito Higashiyama, Yoshitsugu Miyazaki, Yoichi Hirakata, Kazunori Tomono, Yohei Mizuta, Kazuhiro Tsukamoto, and Shigeru Kohno

Effects of short interfering RNA against methicillin-resistant Staphylococcus aureus coagulase in vitro and in vivo
JAC Advance Access published on December 12, 2005
J. Antimicrob. Chemother. 2006 57: 122-126; doi:10.1093/jac/dki416 [Abstract] [Full Text] [PDF] [Request Permissions]  

A. Glasmacher, O. A. Cornely, K. Orlopp, S. Reuter, S. Blaschke, M. Eichel, G. Silling, B. Simons, G. Egerer, M. Siemann, M. Florek, R. Schnitzler, P. Ebeling, J. Ritter, H. Reinel, P. Schütt, H. Fischer, C. Hahn, and G. Just-Nuebling

Caspofungin treatment in severely ill, immunocompromised patients: a case-documentation study of 118 patients
JAC Advance Access published on November 24, 2005
J. Antimicrob. Chemother. 2006 57: 127-134; doi:10.1093/jac/dki410 [Abstract] [Full Text] [PDF] [Request Permissions]  

Brief reports:

Peter A. Warn, Andrew Sharp, and David W. Denning

In vitro activity of a new triazole BAL4815, the active component of BAL8557 (the water-soluble prodrug), against Aspergillus spp.
JAC Advance Access published on November 10, 2005
J. Antimicrob. Chemother. 2006 57: 135-138; doi:10.1093/jac/dki399 [Abstract] [Full Text] [PDF] [Request Permissions]  

Alper Ergin, Serpil Ercis, and Gülsen Hasçelik

Macrolide resistance mechanisms and in vitro susceptibility patterns of viridans group streptococci isolated from blood cultures
JAC Advance Access published on November 16, 2005
J. Antimicrob. Chemother. 2006 57: 139-141; doi:10.1093/jac/dki404 [Abstract] [Full Text] [PDF] [Request Permissions]  

Najiby Kassis-Chikhani, Dominique Decré, Valérie Gautier, Béatrice Burghoffer, Faouzi Saliba, Daniele Mathieu, Didier Samuel, Denis Castaing, Jean-Claude Petit, Elisabeth Dussaix, and Guillaume Arlet

First outbreak of multidrug-resistant Klebsiella pneumoniae carrying bla_VIM-1 and bla_SHV-5 in a French university hospital
JAC Advance Access published on November 10, 2005
J. Antimicrob. Chemother. 2006 57: 142-145; doi:10.1093/jac/dki389 [Abstract] [Full Text] [PDF] [Request Permissions]  

Fabien Garnier, Delphine Chainier, Timothy Walsh, Asa Karlsson, Anne Bolmström, Carole Grelaud, Marcelle Mounier, François Denis, and Marie-Cécile Ploy

A 1 year surveillance study of glycopeptide-intermediate Staphylococcus aureus strains in a French hospital
JAC Advance Access published on November 14, 2005
J. Antimicrob. Chemother. 2006 57: 146-149; doi:10.1093/jac/dki413 [Abstract] [Full Text] [PDF] [Request Permissions]  

Correspondence:

C. De Gascun, L. Rajan, E. O'Neill, and E. G. Smyth

Linezolid use in sepsis due to methicillin-susceptible Staphylococcus aureus
JAC Advance Access published on October 21, 2005
J. Antimicrob. Chemother. 2006 57: 150-151; doi:10.1093/jac/dki394 [Extract] [Full Text] [PDF] [Request Permissions]  

Oliver A. Cornely, Andrew J. Ullmann, and Meinolf Karthaus

Comment on: Evidence-based review of antifungal prophylaxis in neutropenic patients with haematological malignancies
JAC Advance Access published on November 28, 2005
J. Antimicrob. Chemother. 2006 57: 151-152; doi:10.1093/jac/dki415 [Extract] [Full Text] [PDF] [Request Permissions]  

Axel Glasmacher and Archibald Prentice

The role of meta-analysis in the evaluation of antifungal prophylaxis: authors' response
JAC Advance Access published on November 28, 2005
J. Antimicrob. Chemother. 2006 57: 152-154; doi:10.1093/jac/dki431 [Extract] [Full Text] [PDF] [Request Permissions]  

Neil Woodford, Elizabeth J. Fagan, and Matthew J. Ellington

Multiplex PCR for rapid detection of genes encoding CTX-M extended-spectrum ß-lactamases
JAC Advance Access published on November 10, 2005
J. Antimicrob. Chemother. 2006 57: 154-155; doi:10.1093/jac/dki412 [Extract] [Full Text] [PDF] [Request Permissions]  

A. Hamouda and S. G. B. Amyes

Development of highly ciprofloxacin-resistant laboratory mutants of Acinetobacter baumannii lacking topoisomerase IV gene mutations
JAC Advance Access published on November 15, 2005
J. Antimicrob. Chemother. 2006 57: 155-156; doi:10.1093/jac/dki397 [Extract] [Full Text] [PDF] [Request Permissions]  

Yeon-Joon Park, Seungok Lee, Yang Ree Kim, Eun-Jee Oh, Gun-Jo Woo, and Kyungwon Lee

Occurrence of extended-spectrum ß-lactamases and plasmid-mediated AmpC ß-lactamases among Korean isolates of Proteus mirabilis
JAC Advance Access published on November 10, 2005
J. Antimicrob. Chemother. 2006 57: 156-158; doi:10.1093/jac/dki408 [Extract] [Full Text] [PDF] [Request Permissions]  

Evgenia Metzidie, Evangelos N. Manolis, Spyros Pournaras, Danai Sofianou, and Athanassios Tsakris

Spread of an unusual penicillin- and imipenem-resistant but ampicillin-susceptible phenotype among Enterococcus faecalis clinical isolates
JAC Advance Access published on November 24, 2005
J. Antimicrob. Chemother. 2006 57: 158-160; doi:10.1093/jac/dki427 [Extract] [Full Text] [PDF] [Request Permissions]  

Enrico Fiaccadori, Umberto Maggiore, Carlo Rotelli, Roberto Giacosa, Elisabetta Parenti, Aderville Cabassi, Kraisith Ariya, and Lausoontornsiri Wirote

Thrombotic-thrombocytopenic purpura following malaria prophylaxis with mefloquine
JAC Advance Access published on November 12, 2005
J. Antimicrob. Chemother. 2006 57: 160-161; doi:10.1093/jac/dki414 [Extract] [Full Text] [PDF] [Request Permissions]  

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