Journal of Antimicrobial Chemotherapy

Editorials:

David S. Reeves, Colin W. E. Drummond, and Mandy Hill

Journal of Antimicrobial Chemotherapy: optional open access and not-for-profit
JAC Advance Access published on October 11, 2005
J. Antimicrob. Chemother. 2005 56: 799-802; doi:10.1093/jac/dki384 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Leonard Leibovici and David Reeves

Systematic reviews and meta-analyses in the Journal of Antimicrobial Chemotherapy
JAC Advance Access published on September 15, 2005
J. Antimicrob. Chemother. 2005 56: 803-804; doi:10.1093/jac/dki340 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Leading articles:

Ronald B. Turner and J. Owen Hendley

Virucidal hand treatments for prevention of rhinovirus infection
JAC Advance Access published on September 13, 2005
J. Antimicrob. Chemother. 2005 56: 805-807; doi:10.1093/jac/dki329 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Review:

F. Pulido, E. Ribera, S. Moreno, A. Muñoz, D. Podzamczer, M. A. del Pozo, A. Rivero, F. Rodríguez, I. Sanjoaquín, R. Teira, P. Viciana, C. Villalonga, A. Antela, J. Carmena, J. Ena, E. Gonzalez, J. M. Kindelán, J. Mallolas, M. Márquez, and E. Martínez

Once-daily antiretroviral therapy: Spanish Consensus Statement
JAC Advance Access published on September 8, 2005
J. Antimicrob. Chemother. 2005 56: 808-818; doi:10.1093/jac/dki320 [Abstract] [Full Text] [PDF] [Request Permissions]  

Original articles:

Aurora García, Ferran Navarro, Elisenda Miró, Beatriz Mirelis, Susana Campoy, and Pere Coll

Characterization of the highly variable region surrounding the bla_CTX-M-9 gene in non-related Escherichia coli from Barcelona
JAC Advance Access published on September 27, 2005
J. Antimicrob. Chemother. 2005 56: 819-826; doi:10.1093/jac/dki345 [Abstract] [Full Text] [PDF] [Request Permissions]  

Raffaele Zarrilli, Marie-Francoise Tripodi, Anna Di Popolo, Rosaria Fortunato, Maria Bagattini, Margherita Crispino, Anna Florio, Maria Triassi, and Riccardo Utili

Molecular epidemiology of high-level aminoglycoside-resistant enterococci isolated from patients in a university hospital in southern Italy
JAC Advance Access published on September 26, 2005
J. Antimicrob. Chemother. 2005 56: 827-835; doi:10.1093/jac/dki347 [Abstract] [Full Text] [PDF] [Request Permissions]  

Esther Culebras, Iciar Rodríguez-Avial, Carmen Betriu, and Juan J. Picazo

Differences in the DNA sequence of the translational attenuator of several constitutively expressed erm(A) genes from clinical isolates of Streptococcus agalactiae
JAC Advance Access published on September 26, 2005
J. Antimicrob. Chemother. 2005 56: 836-840; doi:10.1093/jac/dki337 [Abstract] [Full Text] [PDF] [Request Permissions]  

Maria Sangvik, Pia Littauer, Gunnar Skov Simonsen, Arnfinn Sundsfjord, and Kristin Hegstad Dahl

mef(A), mef(E) and a new mef allele in macrolide-resistant Streptococcus spp. isolates from Norway
JAC Advance Access published on September 19, 2005
J. Antimicrob. Chemother. 2005 56: 841-846; doi:10.1093/jac/dki327 [Abstract] [Full Text] [PDF] [Request Permissions]  

Miguel Stevens, Jan Balzarini, Oriana Tabarrini, Graciela Andrei, Robert Snoeck, Violetta Cecchetti, Arnaldo Fravolini, Erik De Clercq, and Christophe Pannecouque

Cell-dependent interference of a series of new 6-aminoquinolone derivatives with viral (HIV/CMV) transactivation
JAC Advance Access published on September 8, 2005
J. Antimicrob. Chemother. 2005 56: 847-855; doi:10.1093/jac/dki328 [Abstract] [Full Text] [PDF] [Request Permissions]  

Corinne E. Rouquette-Loughlin, Jacqueline T. Balthazar, and William M. Shafer

Characterization of the MacA–MacB efflux system in Neisseria gonorrhoeae
JAC Advance Access published on September 14, 2005
J. Antimicrob. Chemother. 2005 56: 856-860; doi:10.1093/jac/dki333 [Abstract] [Full Text] [PDF] [Request Permissions]  

Mohd. Akhlakur Rahman, Yoshinao Azuma, Hajime Fukunaga, Tomoyuki Murakami, Kazurou Sugi, Hideto Fukushi, Koshiro Miura, Harumi Suzuki, and Mutsunori Shirai

Serotonin and melatonin, neurohormones for homeostasis, as novel inhibitors of infections by the intracellular parasite chlamydia
JAC Advance Access published on September 19, 2005
J. Antimicrob. Chemother. 2005 56: 861-868; doi:10.1093/jac/dki331 [Abstract] [Full Text] [PDF] Supplementary data [Request Permissions]  

Marilaine Mota-Meira, Helene Morency, and Marc C. Lavoie

In vivo activity of mutacin B-Ny266
JAC Advance Access published on September 9, 2005
J. Antimicrob. Chemother. 2005 56: 869-871; doi:10.1093/jac/dki295 [Abstract] [Full Text] [PDF] [Request Permissions]  

Charles E. Edmiston, Jr, Candace J. Krepel, Karen S. Kehl, Gary R. Seabrook, Lewis B. Somberg, G. Hossein Almassi, Timothy L. Smith, Todd A. Loehrl, Kellie R. Brown, Brian D. Lewis, and Jonathan B. Towne

Comparative in vitro antimicrobial activity of a novel quinolone, garenoxacin, against aerobic and anaerobic microbial isolates recovered from general, vascular, cardiothoracic and otolaryngologic surgical patients
JAC Advance Access published on September 26, 2005
J. Antimicrob. Chemother. 2005 56: 872-878; doi:10.1093/jac/dki348 [Abstract] [Full Text] [PDF] [Request Permissions]  

Samuel M. Moskowitz, Jessica M. Foster, Julia C. Emerson, Ronald L. Gibson, and Jane L. Burns

Use of Pseudomonas biofilm susceptibilities to assign simulated antibiotic regimens for cystic fibrosis airway infection
JAC Advance Access published on September 27, 2005
J. Antimicrob. Chemother. 2005 56: 879-886; doi:10.1093/jac/dki338 [Abstract] [Full Text] [PDF] Supplementary data [Request Permissions]  

Russell E. Lewis and Dimitrios P. Kontoyiannis

Micafungin in combination with voriconazole in Aspergillus species: a pharmacodynamic approach for detection of combined antifungal activity in vitro
JAC Advance Access published on September 27, 2005
J. Antimicrob. Chemother. 2005 56: 887-892; doi:10.1093/jac/dki343 [Abstract] [Full Text] [PDF] [Request Permissions]  

David S. Burgess and Christopher R. Frei

Comparison of ß-lactam regimens for the treatment of Gram-negative pulmonary infections in the intensive care unit based on pharmacokinetics/pharmacodynamics
JAC Advance Access published on September 14, 2005
J. Antimicrob. Chemother. 2005 56: 893-898; doi:10.1093/jac/dki335 [Abstract] [Full Text] [PDF] [Request Permissions]  

Andreas H. Groll, Diana Mickiene, Vidmantas Petraitis, Ruta Petraitiene, Amy Kelaher, Alia Sarafandi, Gudrun Wuerthwein, John Bacher, and Thomas J. Walsh

Compartmental pharmacokinetics and tissue distribution of the antifungal triazole ravuconazole following intravenous administration of its di-lysine phosphoester prodrug (BMS-379224) in rabbits
JAC Advance Access published on September 19, 2005
J. Antimicrob. Chemother. 2005 56: 899-907; doi:10.1093/jac/dki287 [Abstract] [Full Text] [PDF] [Request Permissions]  

Reshma Saskia Autar, Marta Boffito, Elly Hassink, Ferdinand W. N. M. Wit, Jintanat Ananworanich, Umaporn Siangphoe, Anton Pozniak, David A. Cooper, Praphan Phanuphak, Joep M. A. Lange, Kiat Ruxrungtham, and David M. Burger

Interindividual variability of once-daily ritonavir boosted saquinavir pharmacokinetics in Thai and UK patients
JAC Advance Access published on October 4, 2005
J. Antimicrob. Chemother. 2005 56: 908-913; doi:10.1093/jac/dki354 [Abstract] [Full Text] [PDF] [Request Permissions]  

Hande Arslan, Özlem Kurt Azap, Önder Ergönül, and Funda Timurkaynak on behalf of the Urinary Tract Infection Study Group

Risk factors for ciprofloxacin resistance among Escherichia coli strains isolated from community-acquired urinary tract infections in Turkey
JAC Advance Access published on September 20, 2005
J. Antimicrob. Chemother. 2005 56: 914-918; doi:10.1093/jac/dki344 [Abstract] [Full Text] [PDF] [Request Permissions]  

Kuo-Ming Yeh, Tzong-Shi Chiueh, L. K. Siu, Jung-Chung Lin, Paul K. S. Chan, Ming-Yieh Peng, Hsiang-Lin Wan, Jenn-Han Chen, Bor-Shen Hu, Cherng-Lih Perng, Jang-Jih Lu, and Feng-Yee Chang

Experience of using convalescent plasma for severe acute respiratory syndrome among healthcare workers in a Taiwan hospital
JAC Advance Access published on September 23, 2005
J. Antimicrob. Chemother. 2005 56: 919-922; doi:10.1093/jac/dki346 [Abstract] [Full Text] [PDF] [Request Permissions]  

Andrew F. Shorr, Mark J. Kunkel, and Marin Kollef

Linezolid versus vancomycin for Staphylococcus aureus bacteraemia: pooled analysis of randomized studies
JAC Advance Access published on September 29, 2005
J. Antimicrob. Chemother. 2005 56: 923-929; doi:10.1093/jac/dki355 [Abstract] [Full Text] [PDF] [Request Permissions]  

Antimicrobial practice:

Annemiek E. Akkerman, Marijke M. Kuyvenhoven, Johannes C. van der Wouden, and Theo J. M. Verheij

Determinants of antibiotic overprescribing in respiratory tract infections in general practice
JAC Advance Access published on September 9, 2005
J. Antimicrob. Chemother. 2005 56: 930-936; doi:10.1093/jac/dki283 [Abstract] [Full Text] [PDF] [Request Permissions]  

Yaron Razon, Shai Ashkenazi, Avner Cohen, Eli Hering, Shlomo Amzel, Hanan Babilsky, Arie Bahir, Eli Gazala, and Itzhak Levy

Effect of educational intervention on antibiotic prescription practices for upper respiratory infections in children: a multicentre study
JAC Advance Access published on September 27, 2005
J. Antimicrob. Chemother. 2005 56: 937-940; doi:10.1093/jac/dki339 [Abstract] [Full Text] [PDF] [Request Permissions]  

Rogier M. Hopstaken, Samuel Coenen, and Christopher C. Butler

Treating patients not diagnoses: challenging assumptions underlying the investigation and management of LRTI in general practice
JAC Advance Access published on September 8, 2005
J. Antimicrob. Chemother. 2005 56: 941-943; doi:10.1093/jac/dki330 [Abstract] [Full Text] [PDF] [Request Permissions]  

Brief reports:

Mandy Wootton, Peter M. Bennett, Alasdair P. MacGowan, and Timothy R. Walsh

Reduced expression of the atl autolysin gene and susceptibility to autolysis in clinical heterogeneous glycopeptide-intermediate Staphylococcus aureus (hGISA) and GISA strains
JAC Advance Access published on September 12, 2005
J. Antimicrob. Chemother. 2005 56: 944-947; doi:10.1093/jac/dki289 [Abstract] [Full Text] [PDF] [Request Permissions]  

Cédric Cagliero, Christian Mouline, Sophie Payot, and Axel Cloeckaert

Involvement of the CmeABC efflux pump in the macrolide resistance of Campylobacter coli
JAC Advance Access published on September 12, 2005
J. Antimicrob. Chemother. 2005 56: 948-950; doi:10.1093/jac/dki292 [Abstract] [Full Text] [PDF] [Request Permissions]  

Joan L. Robinson, Gerda Tawfik, Lynora Saxinger, Linda Stang, Wai Etches, and Bonita Lee

Stability of heparin and physical compatibility of heparin/antibiotic solutions in concentrations appropriate for antibiotic lock therapy
JAC Advance Access published on September 9, 2005
J. Antimicrob. Chemother. 2005 56: 951-953; doi:10.1093/jac/dki311 [Abstract] [Full Text] [PDF] [Request Permissions]  

R. Karl Malcolm, A. David Woolfson, Clare F. Toner, Ryan J. Morrow, and Stephen D. McCullagh

Long-term, controlled release of the HIV microbicide TMC120 from silicone elastomer vaginal rings
JAC Advance Access published on September 9, 2005
J. Antimicrob. Chemother. 2005 56: 954-956; doi:10.1093/jac/dki326 [Abstract] [Full Text] [PDF] [Request Permissions]  

M. Liao, P. S. Ruddock, A. S. Rizvi, S. H. Hall, F. S. French, and J. R. Dillon

Cationic peptide of the male reproductive tract, HE2, displays antimicrobial activity against Neisseria gonorrhoeae, Staphylococcus aureus and Enterococcus faecalis
JAC Advance Access published on September 29, 2005
J. Antimicrob. Chemother. 2005 56: 957-961; doi:10.1093/jac/dki350 [Abstract] [Full Text] [PDF] [Request Permissions]  

David C. Bean, David M. Livermore, Iro Papa, and Lucinda M. C. Hall

Resistance among Escherichia coli to sulphonamides and other antimicrobials now little used in man
JAC Advance Access published on September 8, 2005
J. Antimicrob. Chemother. 2005 56: 962-964; doi:10.1093/jac/dki332 [Abstract] [Full Text] [PDF] [Request Permissions]  

Jung Mogg Kim, Joo Sung Kim, Nayoung Kim, Hyun Chae Jung, and In Sung Song

Distribution of fluoroquinolone MICs in Helicobacter pylori strains from Korean patients
JAC Advance Access published on September 13, 2005
J. Antimicrob. Chemother. 2005 56: 965-967; doi:10.1093/jac/dki334 [Abstract] [Full Text] [PDF] [Request Permissions]  

Marina Protopopova, Colleen Hanrahan, Boris Nikonenko, Rowena Samala, Ping Chen, Jackie Gearhart, Leo Einck, and Carol A. Nacy

Identification of a new antitubercular drug candidate, SQ109, from a combinatorial library of 1,2-ethylenediamines
JAC Advance Access published on September 19, 2005
J. Antimicrob. Chemother. 2005 56: 968-974; doi:10.1093/jac/dki319 [Abstract] [Full Text] [PDF] [Request Permissions]  

Denis D. G. Mater, Philippe Langella, Gérard Corthier, and María José Flores

Evidence of vancomycin resistance gene transfer between enterococci of human origin in the gut of mice harbouring human microbiota
JAC Advance Access published on September 26, 2005
J. Antimicrob. Chemother. 2005 56: 975-978; doi:10.1093/jac/dki336 [Abstract] [Full Text] [PDF] [Request Permissions]  

Sandra Ribes, Ferran Taberner, Alejandro Domenech, Carmen Cabellos, Fe Tubau, Josefina Liñares, Pedro Fernández Viladrich, and Francesc Gudiol

Evaluation of ceftriaxone, vancomycin and rifampicin alone and combined in an experimental model of meningitis caused by highly cephalosporin-resistant Streptococcus pneumoniae ATCC 51916
JAC Advance Access published on September 20, 2005
J. Antimicrob. Chemother. 2005 56: 979-982; doi:10.1093/jac/dki323 [Abstract] [Full Text] [PDF] [Request Permissions]  

Correspondence:

Vincent H. Tam and Michael Nikolaou

Mathematical modelling of resistance emergence
JAC Advance Access published on September 19, 2005
J. Antimicrob. Chemother. 2005 56: 983; doi:10.1093/jac/dki341 [Extract] [Full Text] [PDF] [Request Permissions]  

J. T. Magee

Give them some clues: modelling antibiotic resistance
JAC Advance Access published on September 19, 2005
J. Antimicrob. Chemother. 2005 56: 983-984; doi:10.1093/jac/dki342 [Extract] [Full Text] [PDF] [Request Permissions]  

Julie R. Samuel, Manjula Natarajan, Essam Rizkalla, David M. Livermore, Marina Warner, and Peter Jenkinson

Disagreements between disc diffusion, and MIC-based susceptibility categorizations of ertapenem versus ESBL producers
JAC Advance Access published on September 27, 2005
J. Antimicrob. Chemother. 2005 56: 984-985; doi:10.1093/jac/dki352 [Extract] [Full Text] [PDF] [Request Permissions]  

Frances G. O'Brien, Zainun Zaini, Geoffrey W. Coombs, Julie C. Pearson, Keryn Christiansen, and Warren B. Grubb

Macrolide, lincosamide and streptogramin B resistance in a dominant clone of Australian community methicillin-resistant Staphylococcus aureus
JAC Advance Access published on October 4, 2005
J. Antimicrob. Chemother. 2005 56: 985-986; doi:10.1093/jac/dki351 [Extract] [Full Text] [PDF] [Request Permissions]  

David H. Wyllie, Emma Baxter, Marcus Morgan, and Ian C. J. W. Bowler

Spread of multiresistance and extended-spectrum ß-lactamases amongst urinary Escherichia coli in Oxford, UK
JAC Advance Access published on September 23, 2005
J. Antimicrob. Chemother. 2005 56: 986-988; doi:10.1093/jac/dki349 [Extract] [Full Text] [PDF] [Request Permissions]  

Jane Freeman, Joanna Stott, Simon D. Baines, Warren N. Fawley, and Mark H. Wilcox

Surveillance for resistance to metronidazole and vancomycin in genotypically distinct and UK epidemic Clostridium difficile isolates in a large teaching hospital
JAC Advance Access published on September 29, 2005
J. Antimicrob. Chemother. 2005 56: 988-989; doi:10.1093/jac/dki357 [Extract] [Full Text] [PDF] [Request Permissions]  

Errata:

Robert G. Masterton, Joseph L. Kuti, Philip J. Turner, and David P. Nicolau

The OPTAMA programme: utilizing MYSTIC (2002) to predict critical pharmacodynamic target attainment against nosocomial pathogens in Europe
JAC Advance Access published on October 12, 2005
J. Antimicrob. Chemother. 2005 56: 990; doi:10.1093/jac/dki358 [Extract] [Full Text] [PDF] [Request Permissions]  

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