Journal of Antimicrobial Chemotherapy

Appreciation:

Norman A. Simmons CBE

Professor John David Williams, 3rd March 1931–11th July 2005
JAC Advance Access published on August 10, 2005
J. Antimicrob. Chemother. 2005 56: 607-608; doi:10.1093/jac/dki300 [Extract] [Full Text] [PDF] [Request Permissions]  

Editorials:

Clare L. Jeeves, Colin W. E. Drummond, and David S. Reeves

Conflicts of interest/transparency declarations: new policy
JAC Advance Access published on September 6, 2005
J. Antimicrob. Chemother. 2005 56: 609-610; doi:10.1093/jac/dki313 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Leading articles:

David M. Livermore

Tigecycline: what is it, and where should it be used?
JAC Advance Access published on August 24, 2005
J. Antimicrob. Chemother. 2005 56: 611-614; doi:10.1093/jac/dki291 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

S. Mauss and J. K. Rockstroh

HCV/HIV-coinfection—is there a state of the art after APRICOT and RIBAVIC?
JAC Advance Access published on August 22, 2005
J. Antimicrob. Chemother. 2005 56: 615-618; doi:10.1093/jac/dki277 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

L. P. Randall, N. G. Coldham, and M. J. Woodward

Detection of mutations in Salmonella enterica gyrA, gyrB, parC and parE genes by denaturing high performance liquid chromatography (DHPLC) using standard HPLC instrumentation
JAC Advance Access published on September 1, 2005
J. Antimicrob. Chemother. 2005 56: 619-623; doi:10.1093/jac/dki293 [Abstract] [Full Text] [PDF] [Request Permissions]  

Nam Hoon Kwon, Kun Taek Park, Jin San Moon, Woo Kyung Jung, So Hyun Kim, Jun Man Kim, Soon Keun Hong, Hye Cheung Koo, Yi Seok Joo, and Yong Ho Park

Staphylococcal cassette chromosome mec (SCCmec) characterization and molecular analysis for methicillin-resistant Staphylococcus aureus and novel SCCmec subtype IVg isolated from bovine milk in Korea
JAC Advance Access published on August 26, 2005
J. Antimicrob. Chemother. 2005 56: 624-632; doi:10.1093/jac/dki306 [Abstract] [Full Text] [PDF] [Request Permissions]  

H. Carsenti-Dellamonica, M. Galimand, F. Vandenbos, C. Pradier, P. M. Roger, B. Dunais, M. Sabah, G. Mancini, and P. Dellamonica

In vitro selection of mutants of Streptococcus pneumoniae resistant to macrolides and linezolid: relationship with susceptibility to penicillin G or macrolides
JAC Advance Access published on August 31, 2005
J. Antimicrob. Chemother. 2005 56: 633-642; doi:10.1093/jac/dki301 [Abstract] [Full Text] [PDF] [Request Permissions]  

Toshinobu Horii, Hideaki Muramatsu, and Yoshitsugu Iinuma

Mechanisms of resistance to fluoroquinolones and carbapenems in Pseudomonas putida
JAC Advance Access published on July 26, 2005
J. Antimicrob. Chemother. 2005 56: 643-647; doi:10.1093/jac/dki254 [Abstract] [Full Text] [PDF] [Request Permissions]  

Michaela Schmidtke, Elke Hammerschmidt, Susanne Schüler, Roland Zell, Eckhard Birch-Hirschfeld, Vadim A. Makarov, Olga B. Riabova, and Peter Wutzler

Susceptibility of coxsackievirus B3 laboratory strains and clinical isolates to the capsid function inhibitor pleconaril: antiviral studies with virus chimeras demonstrate the crucial role of amino acid 1092 in treatment
JAC Advance Access published on September 8, 2005
J. Antimicrob. Chemother. 2005 56: 648-656; doi:10.1093/jac/dki263 [Abstract] [Full Text] [PDF] [Request Permissions]  

G. Vedel

Simple method to determine ß-lactam resistance phenotypes in Pseudomonas aeruginosa using the disc agar diffusion test
JAC Advance Access published on September 6, 2005
J. Antimicrob. Chemother. 2005 56: 657-664; doi:10.1093/jac/dki303 [Abstract] [Full Text] [PDF] [Request Permissions]  

Cláudia N. H. Marques, Vyvyan C. Salisbury, John Greenman, Karen E. Bowker, and Shona M. Nelson

Discrepancy between viable counts and light output as viability measurements, following ciprofloxacin challenge of self-bioluminescent Pseudomonas aeruginosa biofilms
JAC Advance Access published on August 16, 2005
J. Antimicrob. Chemother. 2005 56: 665-671; doi:10.1093/jac/dki285 [Abstract] [Full Text] [PDF] [Request Permissions]  

Sébastien Fraud, Jean-Yves Maillard, Michael A. Kaminski, and Geoffrey W. Hanlon

Activity of amine oxide against biofilms of Streptococcus mutans: a potential biocide for oral care formulations
JAC Advance Access published on September 2, 2005
J. Antimicrob. Chemother. 2005 56: 672-677; doi:10.1093/jac/dki325 [Abstract] [Full Text] [PDF] [Request Permissions]  

Cidália Pina-Vaz, Acácio Gonçalves Rodrigues, Sofia Costa-de-Oliveira, Elisabete Ricardo, and Per-Anders Mårdh

Potent synergic effect between ibuprofen and azoles on Candida resulting from blockade of efflux pumps as determined by FUN-1 staining and flow cytometry
JAC Advance Access published on August 22, 2005
J. Antimicrob. Chemother. 2005 56: 678-685; doi:10.1093/jac/dki264 [Abstract] [Full Text] [PDF] [Request Permissions]  

Lisa W. Halbert, John B. Kaneene, Linda S. Mansfield, Pamela L. Ruegg, Lorin D. Warnick, Scott J. Wells, Chuck P. Fossler, Amy M. Campbell, and Angela M. Geiger-Zwald

Comparison of automated microbroth dilution and agar dilution for antimicrobial susceptibility of Campylobacter jejuni isolated from dairy sources
JAC Advance Access published on August 30, 2005
J. Antimicrob. Chemother. 2005 56: 686-691; doi:10.1093/jac/dki309 [Abstract] [Full Text] [PDF] [Request Permissions]  

Anette Loeffler, Amanda K. Boag, Julia Sung, Jodi A. Lindsay, Luca Guardabassi, Anders Dalsgaard, Heather Smith, Kim B. Stevens, and David H. Lloyd

Prevalence of methicillin-resistant Staphylococcus aureus among staff and pets in a small animal referral hospital in the UK
JAC Advance Access published on September 1, 2005
J. Antimicrob. Chemother. 2005 56: 692-697; doi:10.1093/jac/dki312 [Abstract] [Full Text] [PDF] [Request Permissions]  

Nam Hee Ryoo, Eui-Chong Kim, Seong Geun Hong, Yeon Joon Park, Kyungwon Lee, Il Kwon Bae, Eun Hyang Song, and Seok Hoon Jeong

Dissemination of SHV-12 and CTX-M-type extended-spectrum ß-lactamases among clinical isolates of Escherichia coli and Klebsiella pneumoniae and emergence of GES-3 in Korea
JAC Advance Access published on September 2, 2005
J. Antimicrob. Chemother. 2005 56: 698-702; doi:10.1093/jac/dki324 [Abstract] [Full Text] [PDF] [Request Permissions]  

M. A. Zeitlinger, B. M. Erovic, R. Sauermann, A. Georgopoulos, M. Müller, and C. Joukhadar

Plasma concentrations might lead to overestimation of target site activity of piperacillin in patients with sepsis
JAC Advance Access published on August 24, 2005
J. Antimicrob. Chemother. 2005 56: 703-708; doi:10.1093/jac/dki284 [Abstract] [Full Text] [PDF] [Request Permissions]  

Alejandro Domenech, Sandra Ribes, Carmen Cabellos, Ferran Taberner, Fe Tubau, M. Angeles Domínguez, Abelardo Montero, Josefina Liñares, Javier Ariza, and Francesc Gudiol

Experimental study on the efficacy of combinations of glycopeptides and ß-lactams against Staphylococcus aureus with reduced susceptibility to glycopeptides
JAC Advance Access published on August 24, 2005
J. Antimicrob. Chemother. 2005 56: 709-716; doi:10.1093/jac/dki294 [Abstract] [Full Text] [PDF] [Request Permissions]  

Jane Freeman, Simon D. Baines, Daniela Jabes, and Mark H. Wilcox

Comparison of the efficacy of ramoplanin and vancomycin in both in vitro and in vivo models of clindamycin-induced Clostridium difficile infection
JAC Advance Access published on September 5, 2005
J. Antimicrob. Chemother. 2005 56: 717-725; doi:10.1093/jac/dki321 [Abstract] [Full Text] [PDF] [Request Permissions]  

Masood A. Khan, Tahseen H. Nasti, and M. Owais

Incorporation of amphotericin B in tuftsin-bearing liposomes showed enhanced efficacy against systemic cryptococcosis in leucopenic mice
JAC Advance Access published on August 26, 2005
J. Antimicrob. Chemother. 2005 56: 726-731; doi:10.1093/jac/dki307 [Abstract] [Full Text] [PDF] [Request Permissions]  

Cristina Pichardo, Fernando Docobo-Pérez, Maria E. Pachón-Ibáñez, Manuel E. Jiménez-Mejías, Andrés García-Curiel, F. Javier Caballero-Granado, Ignacio Moreno-Maqueda, and Jerónimo Pachón

Efficacy of ß-lactams against experimental pneumococcal endocarditis caused by strains with different susceptibilities to penicillin
JAC Advance Access published on September 8, 2005
J. Antimicrob. Chemother. 2005 56: 732-737; doi:10.1093/jac/dki304 [Abstract] [Full Text] [PDF] [Request Permissions]  

Lisa M. Almond, Patrick G. Hoggard, Damitha Edirisinghe, Saye H. Khoo, and David J. Back

Intracellular and plasma pharmacokinetics of efavirenz in HIV-infected individuals
JAC Advance Access published on September 1, 2005
J. Antimicrob. Chemother. 2005 56: 738-744; doi:10.1093/jac/dki308 [Abstract] [Full Text] [PDF] [Request Permissions]  

Punnee Pitisuttithum, Ricardo Negroni, John R. Graybill, Beatriz Bustamante, Peter Pappas, Stanley Chapman, Roberta S. Hare, and Catherine J. Hardalo

Activity of posaconazole in the treatment of central nervous system fungal infections
JAC Advance Access published on August 31, 2005
J. Antimicrob. Chemother. 2005 56: 745-755; doi:10.1093/jac/dki288 [Abstract] [Full Text] [PDF] [Request Permissions]  

Brief reports:

Naoko Chiba, Reiko Kobayashi, Keiko Hasegawa, Miyuki Morozumi, Eiichi Nakayama, Takeshi Tajima, Satoshi Iwata, and Kimiko Ubukata on behalf of the Acute Respiratory Diseases Study Group

Antibiotic susceptibility according to genotype of penicillin-binding protein and macrolide resistance genes, and serotype of Streptococcus pneumoniae isolates from community-acquired pneumonia in children
JAC Advance Access published on August 30, 2005
J. Antimicrob. Chemother. 2005 56: 756-760; doi:10.1093/jac/dki302 [Abstract] [Full Text] [PDF] [Request Permissions]  

S. Pournaras, M. Maniati, N. Spanakis, A. Ikonomidis, P. T. Tassios, A. Tsakris, N. J. Legakis, and A. N. Maniatis

Spread of efflux pump-overexpressing, non-metallo-ß-lactamase-producing, meropenem-resistant but ceftazidime-susceptible Pseudomonas aeruginosa in a region with bla_VIM endemicity
JAC Advance Access published on August 22, 2005
J. Antimicrob. Chemother. 2005 56: 761-764; doi:10.1093/jac/dki296 [Abstract] [Full Text] [PDF] [Request Permissions]  

Wondwossen A. Gebreyes, Siddhartha Thakur, and W. E. Morgan Morrow

Campylobacter coli: prevalence and antimicrobial resistance in antimicrobial-free (ABF) swine production systems
JAC Advance Access published on August 24, 2005
J. Antimicrob. Chemother. 2005 56: 765-768; doi:10.1093/jac/dki305 [Abstract] [Full Text] [PDF] [Request Permissions]  

Kristen N. Schurek, Heather J. Adam, Christine G. Siemens, Chris J. Hoban, Daryl J. Hoban, and George G. Zhanel

Are fluoroquinolone-susceptible isolates of Streptococcus pneumoniae really susceptible? A comparison of resistance mechanisms in Canadian isolates from 1997 and 2003
JAC Advance Access published on August 26, 2005
J. Antimicrob. Chemother. 2005 56: 769-772; doi:10.1093/jac/dki315 [Abstract] [Full Text] [PDF] [Request Permissions]  

D. J. Farrell, I. Morrissey, S. Bakker, S. Buckridge, and D. Felmingham

Global distribution of TEM-1 and ROB-1 ß-lactamases in Haemophilus influenzae
JAC Advance Access published on August 11, 2005
J. Antimicrob. Chemother. 2005 56: 773-776; doi:10.1093/jac/dki281 [Abstract] [Full Text] [PDF] [Request Permissions]  

Anna Maria Tortorano, Anna Prigitano, Emanuela Biraghi, and Maria Anna Viviani on behalf of the FIMUA–ECMM Candidaemia Study Group

The European Confederation of Medical Mycology (ECMM) survey of candidaemia in Italy: in vitro susceptibility of 375 Candida albicans isolates and biofilm production
JAC Advance Access published on September 6, 2005
J. Antimicrob. Chemother. 2005 56: 777-779; doi:10.1093/jac/dki310 [Abstract] [Full Text] [PDF] [Request Permissions]  

J. Tamayo, E. Pérez-Trallero, J. L. Gómez-Garcés, and J. I. Alós on behalf of the Spanish Group for the Study of Infection in the Primary Health Care Setting (IAP-SEIMC)

Resistance to macrolides, clindamycin and telithromycin in Streptococcus pyogenes isolated in Spain during 2004
JAC Advance Access published on August 24, 2005
J. Antimicrob. Chemother. 2005 56: 780-782; doi:10.1093/jac/dki286 [Abstract] [Full Text] [PDF] [Request Permissions]  

Carmina Martínez-Marín, Lorena Huelves, Gema del Prado, José I. García-Cía, Carlos Cenjor, Carmen Ponte, Juan J. Granizo, and Francisco Soriano

Effect of erythromycin treatment delay on therapeutic outcome of experimental acute otitis media caused by Streptococcus pneumoniae
JAC Advance Access published on September 6, 2005
J. Antimicrob. Chemother. 2005 56: 783-786; doi:10.1093/jac/dki322 [Abstract] [Full Text] [PDF] [Request Permissions]  

Stefanie Swoboda, Stefan Fritz, Marcus E. Martignoni, Rita A. Feldhues, Torsten Hoppe-Tichy, Markus W. Buchler, and Heinrich K. Geiss

Varying linezolid susceptibility of vancomycin-resistant Enterococcus faecium isolates during therapy: a case report
JAC Advance Access published on September 5, 2005
J. Antimicrob. Chemother. 2005 56: 787-789; doi:10.1093/jac/dki318 [Abstract] [Full Text] [PDF] [Request Permissions]  

Elena Seminari, Gianluca Gentilini, Laura Galli, Hamid Hasson, Anna Danise, Elisabetta Carini, Fernanda Dorigatti, Armando Soldarini, Andriano Lazzarin, and Antonella Castagna

Higher plasma lopinavir concentrations are associated with a moderate rise in cholestasis markers in HIV-infected patients
JAC Advance Access published on September 5, 2005
J. Antimicrob. Chemother. 2005 56: 790-792; doi:10.1093/jac/dki314 [Abstract] [Full Text] [PDF] [Request Permissions]  

Correspondence:

M. F. N. Twagira, J. J. Wade, I. Eltringham, and M. Smith

Development of a real-time PCR assay on the Roche Light-Cycler for the detection of erm and mef erythromycin resistance genes in ß-haemolytic streptococci
JAC Advance Access published on August 26, 2005
J. Antimicrob. Chemother. 2005 56: 793-794; doi:10.1093/jac/dki290 [Extract] [Full Text] [PDF] [Request Permissions]  

Parham Sendi, Peter Graber, and Werner Zimmerli

Loss of mecA gene in Staphylococcus epidermidis after prolonged therapy with vancomycin
JAC Advance Access published on September 2, 2005
J. Antimicrob. Chemother. 2005 56: 794-795; doi:10.1093/jac/dki316 [Extract] [Full Text] [PDF] [Request Permissions]  

David J. Farrell and David Felmingham

The PROTEKT global study (year 4) demonstrates a continued lack of resistance development to telithromycin in Streptococcus pneumoniae
JAC Advance Access published on August 9, 2005
J. Antimicrob. Chemother. 2005 56: 795-797; doi:10.1093/jac/dki282 [Extract] [Full Text] [PDF] [Request Permissions]  

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