Journal of Antimicrobial Chemotherapy

Leading articles:

Tamiko Hisanaga, Daryl J. Hoban, and George G. Zhanel

Mechanisms of resistance to telithromycin in Streptococcus pneumoniae
JAC Advance Access published on July 8, 2005
J. Antimicrob. Chemother. 2005 56: 447-450; doi:10.1093/jac/dki249 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Meeting report:

D. M. Livermore and P. M. Hawkey

CTX-M: changing the face of ESBLs in the UK
JAC Advance Access published on July 8, 2005
J. Antimicrob. Chemother. 2005 56: 451-454; doi:10.1093/jac/dki239 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Reviews:

Alan P. Johnson, Andrew Pearson, and Georgia Duckworth

Surveillance and epidemiology of MRSA bacteraemia in the UK
JAC Advance Access published on July 26, 2005
J. Antimicrob. Chemother. 2005 56: 455-462; doi:10.1093/jac/dki266 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Patrice Nordmann and Laurent Poirel

Emergence of plasmid-mediated resistance to quinolones in Enterobacteriaceae
JAC Advance Access published on July 14, 2005
J. Antimicrob. Chemother. 2005 56: 463-469; doi:10.1093/jac/dki245 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

George A. Pankey

Tigecycline
JAC Advance Access published on July 22, 2005
J. Antimicrob. Chemother. 2005 56: 470-480; doi:10.1093/jac/dki248 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Stephen G. Tristram, Rebecca Hawes, and Juliana Souprounov

Variation in selected regions of bla_TEM genes and promoters in Haemophilus influenzae
JAC Advance Access published on July 8, 2005
J. Antimicrob. Chemother. 2005 56: 481-484; doi:10.1093/jac/dki238 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Kristina Kadlec, Corinna Kehrenberg, and Stefan Schwarz

Molecular basis of resistance to trimethoprim, chloramphenicol and sulphonamides in Bordetella bronchiseptica
JAC Advance Access published on July 26, 2005
J. Antimicrob. Chemother. 2005 56: 485-490; doi:10.1093/jac/dki262 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Laurent Mamelli, Valérie Prouzet-Mauléon, Jean-Marie Pagès, Francis Mégraud, and Jean-Michel Bolla

Molecular basis of macrolide resistance in Campylobacter: role of efflux pumps and target mutations
JAC Advance Access published on July 29, 2005
J. Antimicrob. Chemother. 2005 56: 491-497; doi:10.1093/jac/dki253 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Christine T. Ong, Chinedum P. Babalola, Charles H. Nightingale, and David P. Nicolau

Penetration, efflux and intracellular activity of tigecycline in human polymorphonuclear neutrophils (PMNs)
JAC Advance Access published on July 15, 2005
J. Antimicrob. Chemother. 2005 56: 498-501; doi:10.1093/jac/dki260 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Auriol C. Williams, Helen F. Galley, Alison M. Watt, and Nigel R. Webster

Differential effects of three antibiotics on T helper cell cytokine expression
JAC Advance Access published on July 8, 2005
J. Antimicrob. Chemother. 2005 56: 502-506; doi:10.1093/jac/dki251 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Christophe Cocuaud, Marie-Hélène Rodier, Gyslaine Daniault, and Christine Imbert

Anti-metabolic activity of caspofungin against Candida albicans and Candida parapsilosis biofilms
JAC Advance Access published on July 22, 2005
J. Antimicrob. Chemother. 2005 56: 507-512; doi:10.1093/jac/dki269 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Tsveta Hadjivassileva, David E. Thurston, and Peter W. Taylor

Pyrrolobenzodiazepine dimers: novel sequence-selective, DNA-interactive, cross-linking agents with activity against Gram-positive bacteria
JAC Advance Access published on July 15, 2005
J. Antimicrob. Chemother. 2005 56: 513-518; doi:10.1093/jac/dki256 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Banu Sancak, Serpil Ercis, Dilek Menemenlioglu, Sule Çolakoglu, and Gülsen Hasçelik

Methicillin-resistant Staphylococcus aureus heterogeneously resistant to vancomycin in a Turkish university hospital
JAC Advance Access published on July 26, 2005
J. Antimicrob. Chemother. 2005 56: 519-523; doi:10.1093/jac/dki272 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Holli Lancaster, Raman Bedi, Michael Wilson, and Peter Mullany

The maintenance in the oral cavity of children of tetracycline-resistant bacteria and the genes encoding such resistance
JAC Advance Access published on July 18, 2005
J. Antimicrob. Chemother. 2005 56: 524-531; doi:10.1093/jac/dki259 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Kevin B. Laupland, Daniel B. Gregson, Deirdre L. Church, Terry Ross, and Sameer Elsayed

Invasive Candida species infections: a 5 year population-based assessment
JAC Advance Access published on July 22, 2005
J. Antimicrob. Chemother. 2005 56: 532-537; doi:10.1093/jac/dki258 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Robin Bywater, Malcolm McConville, Ian Phillips, and Thomas Shryock

The susceptibility to growth-promoting antibiotics of Enterococcus faecium isolates from pigs and chickens in Europe
JAC Advance Access published on August 5, 2005
J. Antimicrob. Chemother. 2005 56: 538-543; doi:10.1093/jac/dki273 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

V. I. Enne, A. A. Delsol, G. R. Davis, S. L. Hayward, J. M. Roe, and P. M. Bennett

Assessment of the fitness impacts on Escherichia coli of acquisition of antibiotic resistance genes encoded by different types of genetic element
JAC Advance Access published on July 22, 2005
J. Antimicrob. Chemother. 2005 56: 544-551; doi:10.1093/jac/dki255 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Josée E. Roy-Leon, Wallace D. Lauzon, Baldwin Toye, Neera Singhal, and D. William Cameron

In vitro and in vivo activity of combination antimicrobial agents on Haemophilus ducreyi
JAC Advance Access published on July 26, 2005
J. Antimicrob. Chemother. 2005 56: 552-558; doi:10.1093/jac/dki270 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Heather K. Sun, Su Young Lee, Mary Anne Banevicius, Xiaoli Du, Dana Maglio, and David P. Nicolau

Efficacy of pulsatile amoxicillin and clarithromycin dosing alone and in combination in a murine pneumococcal pneumonia model
JAC Advance Access published on July 15, 2005
J. Antimicrob. Chemother. 2005 56: 559-565; doi:10.1093/jac/dki261 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Antimicrobial practice:

Matthew S. Rogers, Mairi M. Cullen, Emma M. Boxall, and Paul R. Chadwick

Improved compliance with a gentamicin prescribing policy after introduction of a monitoring form
JAC Advance Access published on August 2, 2005
J. Antimicrob. Chemother. 2005 56: 566-568; doi:10.1093/jac/dki279 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Annemiek E. Akkerman, Marijke M. Kuyvenhoven, Johannes C. van der Wouden, and Theo J. M. Verheij

Analysis of under- and overprescribing of antibiotics in acute otitis media in general practice
JAC Advance Access published on July 20, 2005
J. Antimicrob. Chemother. 2005 56: 569-574; doi:10.1093/jac/dki257 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jeroen A. Schouten, Marlies E. Hulscher, Bart-Jan Kullberg, Anton Cox, Inge C. Gyssens, Jos W. van der Meer, and Richard P. Grol

Understanding variation in quality of antibiotic use for community-acquired pneumonia: effect of patient, professional and hospital factors
JAC Advance Access published on July 27, 2005
J. Antimicrob. Chemother. 2005 56: 575-582; doi:10.1093/jac/dki275 [Abstract] [FREE Full Text] [PDF] Supplementary Data [Request Permissions]  

Brief reports:

Bruno González-Zorn, Ana Catalan, Jose A. Escudero, Lucas Domínguez, Tirushet Teshager, Concepción Porrero, and Miguel Angel Moreno

Genetic basis for dissemination of armA
JAC Advance Access published on July 18, 2005
J. Antimicrob. Chemother. 2005 56: 583-585; doi:10.1093/jac/dki246 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Terence Kin Man Cheung, Yiu Wai Chu, Man Yu Chu, Choi Ha Ma, Raymond Wai Hung Yung, and Kai Man Kam

Plasmid-mediated resistance to ciprofloxacin and cefotaxime in clinical isolates of Salmonella enterica serotype Enteritidis in Hong Kong
JAC Advance Access published on July 20, 2005
J. Antimicrob. Chemother. 2005 56: 586-589; doi:10.1093/jac/dki250 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Peter A. Warn, Andrew Sharp, Graham Morrissey, and David W. Denning

Activity of aminocandin (IP960) compared with amphotericin B and fluconazole in a neutropenic murine model of disseminated infection caused by a fluconazole-resistant strain of Candida tropicalis
JAC Advance Access published on July 26, 2005
J. Antimicrob. Chemother. 2005 56: 590-593; doi:10.1093/jac/dki268 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Edward Sionov, Sonia Mendlovic, and Esther Segal

Experimental systemic murine aspergillosis: treatment with polyene and caspofungin combination and G-CSF
JAC Advance Access published on July 8, 2005
J. Antimicrob. Chemother. 2005 56: 594-597; doi:10.1093/jac/dki252 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

Heidi Segal and B. Gay Elisha

Use of Etest MBL strips for the detection of carbapenemases in Acinetobacter baumannii
JAC Advance Access published on July 26, 2005
J. Antimicrob. Chemother. 2005 56: 598; doi:10.1093/jac/dki265 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

J. Andrews, N. Brenwald, D. F. J. Brown, J. Perry, A. King, and C. Gemmell for the BSAC Working Party on Susceptibility Testing

Evaluation of a 10 µg cefoxitin disc for the detection of methicillin resistance in Staphylococcus aureus by BSAC methodology
JAC Advance Access published on July 26, 2005
J. Antimicrob. Chemother. 2005 56: 599-600; doi:10.1093/jac/dki267 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Nigel P. Brenwald, Gail Jevons, Jenny Andrews, Lei Ang, and Adam P. Fraise

Disc methods for detecting AmpC ß-lactamase-producing clinical isolates of Escherichia coli and Klebsiella pneumoniae
JAC Advance Access published on August 8, 2005
J. Antimicrob. Chemother. 2005 56: 600-601; doi:10.1093/jac/dki278 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

François Guerin, Corneliu Henegar, Gabriella Spiridon, Odile Launay, Dominique Salmon-Ceron, and Claire Poyart

Bacterial prostatitis due to Pseudomonas aeruginosa harbouring the bla_VIM-2 metallo-ß-lactamase gene from Saudi Arabia
JAC Advance Access published on August 8, 2005
J. Antimicrob. Chemother. 2005 56: 601-602; doi:10.1093/jac/dki280 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Todd Gleeson, Kyle Petersen, and John Mascola

Successful treatment of Acinetobacter meningitis with meropenem and rifampicin
JAC Advance Access published on July 26, 2005
J. Antimicrob. Chemother. 2005 56: 602-603; doi:10.1093/jac/dki274 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Wai Kin Lee and Betty Wan Yin Young

Antibiotics for childhood community-acquired pneumonia in a region with a high prevalence of penicillin non-susceptible Streptococcus pneumoniae
JAC Advance Access published on July 22, 2005
J. Antimicrob. Chemother. 2005 56: 603-605; doi:10.1093/jac/dki271 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Errata:

D. De Bels, A. Garcia-Filoso, M. Jeanmaire, T. Préseau, Y. Miendje, and J. Devriendt

Successful treatment with linezolid of septic shock secondary to methicillin-resistant Staphylococcus aureus arthritis
JAC Advance Access published on August 2, 2005
J. Antimicrob. Chemother. 2005 56: 606; doi:10.1093/jac/dki276 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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