Journal of Antimicrobial Chemotherapy

Leading articles:

Alan Winston and Marta Boffito

The management of HIV-1 protease inhibitor pharmacokinetic interactions
JAC Advance Access published on June 7, 2005
J. Antimicrob. Chemother. 2005 56: 1-5; doi:10.1093/jac/dki184 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ana Milinkovic and Esteban Martinez

Current perspectives on HIV-associated lipodystrophy syndrome
JAC Advance Access published on May 19, 2005
J. Antimicrob. Chemother. 2005 56: 6-9; doi:10.1093/jac/dki165 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Reviews:

Osmond J. D'Cruz and Fatih M. Uckun

Stampidine: a selective oculo-genital microbicide
JAC Advance Access published on May 26, 2005
J. Antimicrob. Chemother. 2005 56: 10-19; doi:10.1093/jac/dki168 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Keith Poole

Efflux-mediated antimicrobial resistance
JAC Advance Access published on May 24, 2005
J. Antimicrob. Chemother. 2005 56: 20-51; doi:10.1093/jac/dki171 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Johann D. D. Pitout, Patrice Nordmann, Kevin B. Laupland, and Laurent Poirel

Emergence of Enterobacteriaceae producing extended-spectrum ß-lactamases (ESBLs) in the community
JAC Advance Access published on May 25, 2005
J. Antimicrob. Chemother. 2005 56: 52-59; doi:10.1093/jac/dki166 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

J. M. Andrews for the BSAC Working Party on Susceptibility Testing

BSAC standardized disc susceptibility testing method (version 4)
JAC Advance Access published on May 23, 2005
J. Antimicrob. Chemother. 2005 56: 60-76; doi:10.1093/jac/dki124 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Preeti Saini, Tulika Prasad, Naseem Akhtar Gaur, Suneet Shukla, Sudhakar Jha, Sneha Sudha Komath, Luqman Ahmad Khan, Qazi Mohd. Rizwanul Haq, and Rajendra Prasad

Alanine scanning of transmembrane helix 11 of Cdr1p ABC antifungal efflux pump of Candida albicans: identification of amino acid residues critical for drug efflux
JAC Advance Access published on June 3, 2005
J. Antimicrob. Chemother. 2005 56: 77-86; doi:10.1093/jac/dki183 [Abstract] [FREE Full Text] [PDF] Supplementary Data [Request Permissions]  

Marianne Sunde and Madelaine Norström

The genetic background for streptomycin resistance in Escherichia coli influences the distribution of MICs
JAC Advance Access published on May 16, 2005
J. Antimicrob. Chemother. 2005 56: 87-90; doi:10.1093/jac/dki150 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Shingo Mizunaga, Tomoko Kamiyama, Yoshiko Fukuda, Masahiro Takahata, and Junichi Mitsuyama

Influence of inoculum size of Staphylococcus aureus and Pseudomonas aeruginosa on in vitro activities and in vivo efficacy of fluoroquinolones and carbapenems
JAC Advance Access published on May 12, 2005
J. Antimicrob. Chemother. 2005 56: 91-96; doi:10.1093/jac/dki163 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Rikard Dryselius, Natalia Nekhotiaeva, and Liam Good

Antimicrobial synergy between mRNA- and protein-level inhibitors
JAC Advance Access published on May 24, 2005
J. Antimicrob. Chemother. 2005 56: 97-103; doi:10.1093/jac/dki173 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Aldona L. Baltch, Lawrence H. Bopp, Raymond P. Smith, Phyllis B. Michelsen, and William J. Ritz

Antibacterial activities of gemifloxacin, levofloxacin, gatifloxacin, moxifloxacin and erythromycin against intracellular Legionella pneumophila and Legionella micdadei in human monocytes
JAC Advance Access published on June 7, 2005
J. Antimicrob. Chemother. 2005 56: 104-109; doi:10.1093/jac/dki186 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. Murray, J. E. Coia, H. Mather, and D. J. Brown

Ciprofloxacin resistance in non-typhoidal Salmonella serotypes in Scotland, 1993–2003
JAC Advance Access published on May 24, 2005
J. Antimicrob. Chemother. 2005 56: 110-114; doi:10.1093/jac/dki164 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Henrik Hasman, Dik Mevius, Kees Veldman, Inger Olesen, and Frank M. Aarestrup

ß-Lactamases among extended-spectrum ß-lactamase (ESBL)-resistant Salmonella from poultry, poultry products and human patients in The Netherlands
JAC Advance Access published on June 7, 2005
J. Antimicrob. Chemother. 2005 56: 115-121; doi:10.1093/jac/dki190 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Seungok Lee, Yeon-Joon Park, Myungshin Kim, Hae Kyung Lee, Kyungja Han, Chang Suk Kang, and Moon Won Kang

Prevalence of Ambler class A and D ß-lactamases among clinical isolates of Pseudomonas aeruginosa in Korea
JAC Advance Access published on May 12, 2005
J. Antimicrob. Chemother. 2005 56: 122-127; doi:10.1093/jac/dki160 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Simona Bratu, Pooja Tolaney, Usha Karumudi, John Quale, Mohamad Mooty, Satyen Nichani, and David Landman

Carbapenemase-producing Klebsiella pneumoniae in Brooklyn, NY: molecular epidemiology and in vitro activity of polymyxin B and other agents
JAC Advance Access published on May 25, 2005
J. Antimicrob. Chemother. 2005 56: 128-132; doi:10.1093/jac/dki175 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. C. Fluit, A. Florijn, J. Verhoef, and D. Milatovic

Susceptibility of European ß-lactamase-positive and -negative Haemophilus influenzae isolates from the periods 1997/1998 and 2002/2003
JAC Advance Access published on May 25, 2005
J. Antimicrob. Chemother. 2005 56: 133-138; doi:10.1093/jac/dki167 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Eileen M. Graffunder, Karen E. Preston, Ann M. Evans, and Richard A. Venezia

Risk factors associated with extended-spectrum ß-lactamase-producing organisms at a tertiary care hospital
JAC Advance Access published on May 25, 2005
J. Antimicrob. Chemother. 2005 56: 139-145; doi:10.1093/jac/dki180 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Alastair D. Hay, Michael Thomas, Alan Montgomery, Mark Wetherell, Andrew Lovering, Cliodna McNulty, Deirdre Lewis, Becky Carron, Emma Henderson, and Alasdair MacGowan

The relationship between primary care antibiotic prescribing and bacterial resistance in adults in the community: a controlled observational study using individual patient data
JAC Advance Access published on May 31, 2005
J. Antimicrob. Chemother. 2005 56: 146-153; doi:10.1093/jac/dki181 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Herman Mattie, Kristin Stuertz, Roland Nau, and Jaap T. van Dissel

Pharmacodynamics of antibiotics with respect to bacterial killing of and release of lipoteichoic acid by Streptococcus pneumoniae
JAC Advance Access published on May 26, 2005
J. Antimicrob. Chemother. 2005 56: 154-159; doi:10.1093/jac/dki176 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Naseem Mushtaq, Maria B. Redpath, J. Paul Luzio, and Peter W. Taylor

Treatment of experimental Escherichia coli infection with recombinant bacteriophage-derived capsule depolymerase
JAC Advance Access published on May 24, 2005
J. Antimicrob. Chemother. 2005 56: 160-165; doi:10.1093/jac/dki177 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jackie Imai, Gaurav Singh, Belkys Fernandez, Karl V. Clemons, and David A. Stevens

Efficacy of Abelcet and caspofungin, alone or in combination, against CNS aspergillosis in a murine model
JAC Advance Access published on May 25, 2005
J. Antimicrob. Chemother. 2005 56: 166-171; doi:10.1093/jac/dki178 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brigitte Meyer, Gabriela V. Kornek, Mariam Nikfardjam, Georg Delle Karth, Gottfried Heinz, Gottfried J. Locker, Walter Jaeger, and Florian Thalhammer

Multiple-dose pharmacokinetics of linezolid during continuous venovenous haemofiltration
JAC Advance Access published on May 19, 2005
J. Antimicrob. Chemother. 2005 56: 172-179; doi:10.1093/jac/dki133 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jesús Fortún, Pilar Martín-Dávila, Enrique Navas, Ma Jesús Pérez-Elías, Javier Cobo, Marta Tato, Elia Gómez-G. De la Pedrosa, Enrique Gómez-Mampaso, and Santiago Moreno

Linezolid for the treatment of multidrug-resistant tuberculosis
JAC Advance Access published on May 23, 2005
J. Antimicrob. Chemother. 2005 56: 180-185; doi:10.1093/jac/dki148 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Victoria Latham, Justin Stebbing, Sundhiya Mandalia, Christos Michailidis, Elizabeth Davies, Mark Bower, Brian Gazzard, and Mark Nelson

Adherence to trizivir and tenofovir as a simplified salvage regimen is associated with suppression of viraemia and a decreased cholesterol
JAC Advance Access published on May 23, 2005
J. Antimicrob. Chemother. 2005 56: 186-189; doi:10.1093/jac/dki170 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Carlo Torti, Franco Maggiolo, Andrea Patroni, Fredy Suter, Nicoletta Ladisa, Giuseppe Paraninfo, Piera Pierotti, Anna Maria Orani, Lorenzo Minoli, Claudio Arici, Laura Sighinolfi, Carmine Tinelli, and Giampiero Carosi for the MASTER Cohort

Exploratory analysis for the evaluation of lopinavir/ritonavir-versus efavirenz-based HAART regimens in antiretroviral-naive HIV-positive patients: results from the Italian MASTER Cohort
JAC Advance Access published on May 25, 2005
J. Antimicrob. Chemother. 2005 56: 190-195; doi:10.1093/jac/dki172 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Antimicrobial practice:

Lorraine A. Paterson Davenport, Peter G. Davey, and Jean S. Ker on behalf of the BSAC Undergraduate Education Working Party

An outcome-based approach for teaching prudent antimicrobial prescribing to undergraduate medical students: report of a Working Party of the British Society for Antimicrobial Chemotherapy
JAC Advance Access published on May 24, 2005
J. Antimicrob. Chemother. 2005 56: 196-203; doi:10.1093/jac/dki126 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

R. T. Mayon-White and P. Wiffen

Audit of antibiotic policies in the South East of England, 2004
JAC Advance Access published on May 12, 2005
J. Antimicrob. Chemother. 2005 56: 204-207; doi:10.1093/jac/dki152 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Liselotte Högberg, Thimothy Oke, Patricia Geli, Cecilia Stålsby Lundborg, Otto Cars, and Karl Ekdahl

Reduction in outpatient antibiotic sales for pre-school children: interrupted time series analysis of weekly antibiotic sales data in Sweden 1992–2002
JAC Advance Access published on May 16, 2005
J. Antimicrob. Chemother. 2005 56: 208-215; doi:10.1093/jac/dki147 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Ruby Singh, Carl M. Schroeder, Jianghong Meng, David G. White, Patrick F. McDermott, David D. Wagner, Hanchun Yang, Shabbir Simjee, Chitrita DebRoy, Robert D. Walker, and Shaohua Zhao

Identification of antimicrobial resistance and class 1 integrons in Shiga toxin-producing Escherichia coli recovered from humans and food animals
JAC Advance Access published on May 23, 2005
J. Antimicrob. Chemother. 2005 56: 216-219; doi:10.1093/jac/dki161 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Sylvia Valdezate, Ana Vindel, Juan Antonio Saéz-Nieto, Fernando Baquero, and Rafael Cantón

Preservation of topoisomerase genetic sequences during in vivo and in vitro development of high-level resistance to ciprofloxacin in isogenic Stenotrophomonas maltophilia strains
JAC Advance Access published on May 31, 2005
J. Antimicrob. Chemother. 2005 56: 220-223; doi:10.1093/jac/dki182 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Sam K. Bouchillon, Jack L. Johnson, Daryl J. Hoban, Tim M. Stevens, and Brian M. Johnson

Impact of carbon dioxide on the susceptibility of key respiratory tract pathogens to telithromycin and azithromycin
JAC Advance Access published on May 12, 2005
J. Antimicrob. Chemother. 2005 56: 224-227; doi:10.1093/jac/dki156 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

V. M. French, R. A. Cooper, and P. C. Molan

The antibacterial activity of honey against coagulase-negative staphylococci
JAC Advance Access published on June 7, 2005
J. Antimicrob. Chemother. 2005 56: 228-231; doi:10.1093/jac/dki193 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Philip Bejon, Isaiah Mwangi, Caroline Ngetsa, Salim Mwarumba, James A. Berkley, Brett S. Lowe, Kathryn Maitland, Kevin Marsh, Mike English, and J. Anthony G. Scott

Invasive Gram-negative bacilli are frequently resistant to standard antibiotics for children admitted to hospital in Kilifi, Kenya
JAC Advance Access published on May 19, 2005
J. Antimicrob. Chemother. 2005 56: 232-235; doi:10.1093/jac/dki145 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jacques Albert Dromigny, Pierre Nabeth, Ann Juergens-Behr, and Jean David Perrier-Gros-Claude

Risk factors for antibiotic-resistant Escherichia coli isolated from community-acquired urinary tract infections in Dakar, Senegal
JAC Advance Access published on May 12, 2005
J. Antimicrob. Chemother. 2005 56: 236-239; doi:10.1093/jac/dki158 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

E. Tano, O. Cars, and E. Löwdin

Pharmacodynamic studies of moxifloxacin and erythromycin against intracellular Legionella pneumophila in an in vitro kinetic model
JAC Advance Access published on May 26, 2005
J. Antimicrob. Chemother. 2005 56: 240-242; doi:10.1093/jac/dki159 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Kalpana Gupta, Thomas M. Hooton, and Walter E. Stamm

Isolation of fluoroquinolone-resistant rectal Escherichia coli after treatment of acute uncomplicated cystitis
JAC Advance Access published on May 23, 2005
J. Antimicrob. Chemother. 2005 56: 243-246; doi:10.1093/jac/dki169 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M. O. Husson, N. Wizla-Derambure, D. Turck, P. Gosset, and B. Wallaert

Effect of intermittent inhaled tobramycin on sputum cytokine profiles in cystic fibrosis
JAC Advance Access published on June 2, 2005
J. Antimicrob. Chemother. 2005 56: 247-249; doi:10.1093/jac/dki179 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

Ashraf M. Ahmed, Kimi Furuta, Kei Shimomura, Hidekazu Kawamoto, and Tadashi Shimamoto

Characterization of a multidrug-resistant isolate of Salmonella Paratyphi B from Japan
JAC Advance Access published on May 12, 2005
J. Antimicrob. Chemother. 2005 56: 250-250a; doi:10.1093/jac/dki157 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Felipe Fernández-Cuenca, Alvaro Pascual, and Luis Martínez-Martínez

Hyperproduction of AmpC ß-lactamase in a clinical isolate of Escherichia coli associated with a 30 bp deletion in the attenuator region of ampC
JAC Advance Access published on May 12, 2005
J. Antimicrob. Chemother. 2005 56: 251-252; doi:10.1093/jac/dki149 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

L. Majoros, G. Kardos, P. Feiszt, and B. Szabó

Efficacy of amphotericin B and flucytosine against fluconazole-resistant Candida inconspicua clinical isolates
JAC Advance Access published on May 23, 2005
J. Antimicrob. Chemother. 2005 56: 253-254; doi:10.1093/jac/dki174 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Book reviews:

Andrew Ustianowski

Oxford Handbook of Tropical Medicine, Second Edition • Michael Eddleston, Robert Davidson, Robert Wilkinson and Stephen Pierini • Oxford University Press, Oxford, UK, 2004 • ISBN 0-19-852509-5. £24.95, 712 pp.
J. Antimicrob. Chemother. 2005 56: 255; doi:10.1093/jac/dki154 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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