Journal of Antimicrobial Chemotherapy

Leading articles:

Judith N. Steenbergen, Jeff Alder, Grace M. Thorne, and Francis P. Tally

Daptomycin: a lipopeptide antibiotic for the treatment of serious Gram-positive infections
JAC Advance Access published on February 10, 2005
J. Antimicrob. Chemother. 2005 55: 283-288; doi:10.1093/jac/dkh546 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Christopher Cianci, Nicholas Meanwell, and Mark Krystal

Antiviral activity and molecular mechanism of an orally active respiratory syncytial virus fusion inhibitor
JAC Advance Access published on January 28, 2005
J. Antimicrob. Chemother. 2005 55: 289-292; doi:10.1093/jac/dkh558 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Sara Werber, Itamar Shalit, Ina Fabian, Guy Steuer, Taly Weiss, and Hannah Blau

Moxifloxacin inhibits cytokine-induced MAP kinase and NF-B activation as well as nitric oxide synthesis in a human respiratory epithelial cell line
JAC Advance Access published on January 19, 2005
J. Antimicrob. Chemother. 2005 55: 293-300; doi:10.1093/jac/dkh525 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Gisele Peirano, Yvonne Agersø, Frank M. Aarestrup, and Dalia dos Prazeres Rodrigues

Occurrence of integrons and resistance genes among sulphonamide-resistant Shigella spp. from Brazil
JAC Advance Access published on January 28, 2005
J. Antimicrob. Chemother. 2005 55: 301-305; doi:10.1093/jac/dki012 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

David M. Livermore, Shazad Mushtaq, and Marina Warner

Selectivity of ertapenem for Pseudomonas aeruginosa mutants cross-resistant to other carbapenems
JAC Advance Access published on February 10, 2005
J. Antimicrob. Chemother. 2005 55: 306-311; doi:10.1093/jac/dki009 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Alicia Gomez-Lopez, Emilia Mellado, Juan L. Rodriguez-Tudela, and Manuel Cuenca-Estrella

Susceptibility profile of 29 clinical isolates of Rhodotorula spp. and literature review
JAC Advance Access published on February 4, 2005
J. Antimicrob. Chemother. 2005 55: 312-316; doi:10.1093/jac/dki020 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Alfonso-Javier Carrillo-Muñoz, Guillermo Quindós, Maite Ruesga, Rocío Alonso, Oscar del Valle, Juan Manuel Hernández-Molina, Paul McNicholas, David Loebenberg, and Patricia Santos

Antifungal activity of posaconazole compared with fluconazole and amphotericin B against yeasts from oropharyngeal candidiasis and other infections
JAC Advance Access published on February 10, 2005
J. Antimicrob. Chemother. 2005 55: 317-319; doi:10.1093/jac/dki022 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Surbhi Malhotra-Kumar, Christine Lammens, Sabine Chapelle, Cecile Mallentjer, Joost Weyler, and Herman Goossens

Clonal spread of fluoroquinolone non-susceptible Streptococcus pyogenes
JAC Advance Access published on February 10, 2005
J. Antimicrob. Chemother. 2005 55: 320-325; doi:10.1093/jac/dki011 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

P. L. Ho, Ricky H. L. Shek, K. H. Chow, R. S. Duan, Gannon C. Mak, Eileen L. Lai, W. C. Yam, Kenneth W. Tsang, and W. M. Lai

Detection and characterization of extended-spectrum ß-lactamases among bloodstream isolates of Enterobacter spp. in Hong Kong, 2000–2002
JAC Advance Access published on January 28, 2005
J. Antimicrob. Chemother. 2005 55: 326-332; doi:10.1093/jac/dki010 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Tony Whitehouse, Jorge A. Cepeda, Rob Shulman, Leon Aarons, Ricardo Nalda-Molina, Caroline Tobin, Alasdair MacGowan, Steve Shaw, Chris Kibbler, Mervyn Singer, and A. Peter R. Wilson

Pharmacokinetic studies of linezolid and teicoplanin in the critically ill
JAC Advance Access published on February 10, 2005
J. Antimicrob. Chemother. 2005 55: 333-340; doi:10.1093/jac/dki014 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Juri Karjagin, Rein Pähkla, Tõnis Karki, and Joel Starkopf

Distribution of metronidazole in muscle tissue of patients with septic shock and its efficacy against Bacteroides fragilis in vitro
JAC Advance Access published on February 22, 2005
J. Antimicrob. Chemother. 2005 55: 341-346; doi:10.1093/jac/dkh544 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Pierre-Pascal Poulet, Danielle Duffaut, Pierre Barthet, and Ivan Brumpt

Concentrations and in vivo antibacterial activity of spiramycin and metronidazole in patients with periodontitis treated with high-dose metronidazole and the spiramycin/metronidazole combination
JAC Advance Access published on February 4, 2005
J. Antimicrob. Chemother. 2005 55: 347-351; doi:10.1093/jac/dki013 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Antimicrobial practice:

R. Wenzel, A. Del Favero, C. Kibbler, T. Rogers, C. Rotstein, J. Mauskopf, S. Morris, H. Schlamm, P. Troke, and A. Marciniak

Economic evaluation of voriconazole compared with conventional amphotericin B for the primary treatment of aspergillosis in immunocompromised patients
JAC Advance Access published on February 22, 2005
J. Antimicrob. Chemother. 2005 55: 352-361; doi:10.1093/jac/dkh535 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

V. von Gunten, N. Troillet, J. Beney, K. Boubaker, J.-C. Lüthi, P. Taffé, and J.-P. Reymond

Impact of an interdisciplinary strategy on antibiotic use: a prospective controlled study in three hospitals
JAC Advance Access published on February 10, 2005
J. Antimicrob. Chemother. 2005 55: 362-366; doi:10.1093/jac/dki021 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Yvonne Abbott, Rebecca O'Mahony, Nola Leonard, P. Joseph Quinn, Tanny van der Reijden, Lenie Dijkshoorn, and Séamus Fanning

Characterization of a 2.6 kbp variable region within a class 1 integron found in an Acinetobacter baumannii strain isolated from a horse
JAC Advance Access published on January 28, 2005
J. Antimicrob. Chemother. 2005 55: 367-370; doi:10.1093/jac/dkh543 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ashraf M. Ahmed, Hiroyuki Nakano, and Tadashi Shimamoto

Molecular characterization of integrons in non-typhoid Salmonella serovars isolated in Japan: description of an unusual class 2 integron
JAC Advance Access published on February 10, 2005
J. Antimicrob. Chemother. 2005 55: 371-374; doi:10.1093/jac/dkh534 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

David C. Bean and John D. Klena

Characterization of major clones of antibiotic-resistant Streptococcus pneumoniae in New Zealand by multilocus sequence typing
JAC Advance Access published on January 28, 2005
J. Antimicrob. Chemother. 2005 55: 375-378; doi:10.1093/jac/dki001 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

David Velasco, Maria del Mar Tomas, Monica Cartelle, Alejandro Beceiro, Astrid Perez, Francisca Molina, Rita Moure, Rosa Villanueva, and German Bou

Evaluation of different methods for detecting methicillin (oxacillin) resistance in Staphylococcus aureus
JAC Advance Access published on February 18, 2005
J. Antimicrob. Chemother. 2005 55: 379-382; doi:10.1093/jac/dki017 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M. B. Kerrn, C. Struve, J. Blom, N. Frimodt-Møller, and K. A. Krogfelt

Intracellular persistence of Escherichia coli in urinary bladders from mecillinam-treated mice
JAC Advance Access published on January 28, 2005
J. Antimicrob. Chemother. 2005 55: 383-386; doi:10.1093/jac/dki002 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Matteo Bassetti, Francesco Vitale, Giovanna Melica, Elda Righi, Antonio Di Biagio, Luigi Molfetta, Francesco Pipino, Mario Cruciani, and Dante Bassetti

Linezolid in the treatment of Gram-positive prosthetic joint infections
JAC Advance Access published on February 10, 2005
J. Antimicrob. Chemother. 2005 55: 387-390; doi:10.1093/jac/dki016 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Dirk R. J. Kuypers, Kathleen Claes, Pieter Evenepoel, Bart Maes, and Yves Vanrenterghem

A simplified strategy for clinical management of late cytomegalovirus infection after oral ganciclovir prophylaxis in renal recipients
JAC Advance Access published on February 10, 2005
J. Antimicrob. Chemother. 2005 55: 391-394; doi:10.1093/jac/dki031 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

D. Rao, J. R. Rao, E. Crothers, R. McMullan, D. McDowell, A. McMahon, P. J. Rooney, B. C. Millar, and J. E. Moore

Increased erythromycin resistance in clinical Campylobacter in Northern Ireland—an update
JAC Advance Access published on January 28, 2005
J. Antimicrob. Chemother. 2005 55: 395-396; doi:10.1093/jac/dkh552 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Jean-Winoc Decousser, Imen Methlouthi, Patrick Pina, and Pierre Allouch on behalf of The ColBVH Study

In vitro activity of ertapenem against bacteraemic pneumococci: report of a French multicentre study including 339 strains
JAC Advance Access published on February 10, 2005
J. Antimicrob. Chemother. 2005 55: 396-398; doi:10.1093/jac/dki019 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Marc Scheetz, Pavani Reddy, Michael Postelnick, and John Flaherty

In vivo synergy of daptomycin plus a penicillin agent for MRSA?
JAC Advance Access published on January 28, 2005
J. Antimicrob. Chemother. 2005 55: 398-399; doi:10.1093/jac/dkh554 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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