Journal of Antimicrobial Chemotherapy

Leading articles:

Jan Balzarini, Miguel Stevens, Erik De Clercq, Dominique Schols, and Christophe Pannecouque

Pyridine N-oxide derivatives: unusual anti-HIV compounds with multiple mechanisms of antiviral action
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 135-138; doi:10.1093/jac/dkh530 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Norio Akuta and Hiromitsu Kumada

Influence of hepatitis B virus genotypes on the response to antiviral therapies
JAC Advance Access published on December 23, 2004
J. Antimicrob. Chemother. 2005 55: 139-142; doi:10.1093/jac/dkh533 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Reviews:

R. S. Howell-Jones, M. J. Wilson, K. E. Hill, A. J. Howard, P. E. Price, and D. W. Thomas

A review of the microbiology, antibiotic usage and resistance in chronic skin wounds
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 143-149; doi:10.1093/jac/dkh513 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Arjan Nooteboom, Cees J. van der Linden, and Thijs Hendriks

Whole blood-mediated endothelial permeability and adhesion molecule expression: a model study into the effects of bacteria and antibiotics
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 150-156; doi:10.1093/jac/dkh526 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

R. Skov, R. Smyth, A. R. Larsen, N. Frimodt-Møller, and G. Kahlmeter

Evaluation of cefoxitin 5 and 10 µg discs for the detection of methicillin resistance in staphylococci
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 157-161; doi:10.1093/jac/dkh514 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

David Jackson, Wendy Barclay, and Thomas Zürcher

Characterization of recombinant influenza B viruses with key neuraminidase inhibitor resistance mutations
JAC Advance Access published on January 21, 2005
J. Antimicrob. Chemother. 2005 55: 162-169; doi:10.1093/jac/dkh528 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Kevin A. Nash, Yansheng Zhang, Barbara A. Brown-Elliott, and Richard J. Wallace, Jr

Molecular basis of intrinsic macrolide resistance in clinical isolates of Mycobacterium fortuitum
JAC Advance Access published on December 8, 2004
J. Antimicrob. Chemother. 2005 55: 170-177; doi:10.1093/jac/dkh523 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. Boulos, J. M. Rolain, M. N. Mallet, and D. Raoult

Molecular evaluation of antibiotic susceptibility of Tropheryma whipplei in axenic medium
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 178-181; doi:10.1093/jac/dkh524 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Minna Laatu, Hilpi Rautelin, and Marja-Liisa Hänninen

Susceptibility of Campylobacter hyointestinalis subsp. hyointestinalis to antimicrobial agents and characterization of quinolone-resistant strains
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 182-187; doi:10.1093/jac/dkh537 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Patricia Muñoz, Mar Sánchez-Somolinos, Luis Alcalá, Marta Rodríguez-Créixems, Teresa Peláez, and Emilio Bouza

Candida krusei fungaemia: antifungal susceptibility and clinical presentation of an uncommon entity during 15 years in a single general hospital
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 188-193; doi:10.1093/jac/dkh532 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Manuel Cuenca-Estrella, Dolores Rodriguez, Benito Almirante, Juliette Morgan, Ana Maria Planes, Manel Almela, José Mensa, Ferran Sanchez, Josefina Ayats, Montserrat Gimenez, Margarita Salvado, David W. Warnock, Albert Pahissa, and Juan L. Rodriguez-Tudela on behalf of the Barcelona Candidemia Project Study Group

In vitro susceptibilities of bloodstream isolates of Candida species to six antifungal agents: results from a population-based active surveillance programme, Barcelona, Spain, 2002–2003
JAC Advance Access published on December 23, 2004
J. Antimicrob. Chemother. 2005 55: 194-199; doi:10.1093/jac/dkh548 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ian Morrissey, Marion Robbins, Louise Viljoen, and Derek F. J. Brown

Antimicrobial susceptibility of community-acquired respiratory tract pathogens in the UK during 2002/3 determined locally and centrally by BSAC methods
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 200-208; doi:10.1093/jac/dkh540 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Luis Alou, Lorenzo Aguilar, David Sevillano, María-José Giménez, Olatz Echeverría, María-Luisa Gómez-Lus, and José Prieto

Is there a pharmacodynamic need for the use of continuous versus intermittent infusion with ceftazidime against Pseudomonas aeruginosa? An in vitro pharmacodynamic model
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 209-213; doi:10.1093/jac/dkh536 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Silvia Bellocchio, Roberta Gaziano, Silvia Bozza, Giordano Rossi, Claudia Montagnoli, Katia Perruccio, Mario Calvitti, Lucia Pitzurra, and Luigina Romani

Liposomal amphotericin B activates antifungal resistance with reduced toxicity by diverting Toll-like receptor signalling from TLR-2 to TLR-4
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 214-222; doi:10.1093/jac/dkh542 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Masood A. Khan, Rukhsana Jabeen, T. H. Nasti, and Owais Mohammad

Enhanced anticryptococcal activity of chloroquine in phosphatidylserine-containing liposomes in a murine model
JAC Advance Access published on December 8, 2004
J. Antimicrob. Chemother. 2005 55: 223-228; doi:10.1093/jac/dkh522 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Pasquale Pagliano, Novella Carannante, Marco Rossi, Marina Gramiccia, Luigi Gradoni, Francesco Saverio Faella, and Giovanni Battista Gaeta

Visceral leishmaniasis in pregnancy: a case series and a systematic review of the literature
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 229-233; doi:10.1093/jac/dkh538 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Arlo Upton, Dragana Drinkovic, Sudha Pottumarthy, Teena West, and Arthur J. Morris

Culture results of heart valves resected because of streptococcal endocarditis: insights into duration of treatment to achieve valve sterilization
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 234-239; doi:10.1093/jac/dkh527 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Benjamin A. Lipsky and Uschi Stoutenburgh

Daptomycin for treating infected diabetic foot ulcers: evidence from a randomized, controlled trial comparing daptomycin with vancomycin or semi-synthetic penicillins for complicated skin and skin-structure infections
JAC Advance Access published on January 19, 2005
J. Antimicrob. Chemother. 2005 55: 240-245; doi:10.1093/jac/dkh531 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Chloe Orkin, Justin Stebbing, Mark Nelson, Mark Bower, Margaret Johnson, Sundhiya Mandalia, Rachael Jones, Graeme Moyle, Martin Fisher, and Brian Gazzard

A randomized study comparing a three- and four-drug HAART regimen in first-line therapy (QUAD study)
JAC Advance Access published on December 17, 2004
J. Antimicrob. Chemother. 2005 55: 246-251; doi:10.1093/jac/dkh515 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

François Sanschagrin and Roger C. Levesque

A specific peptide inhibitor of the class B metallo-ß-lactamase L-1 from Stenotrophomonas maltophilia identified using phage display
JAC Advance Access published on January 19, 2005
J. Antimicrob. Chemother. 2005 55: 252-255; doi:10.1093/jac/dkh550 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Monica Monaco, Romina Camilli, Fabio D'Ambrosio, Maria Del Grosso, and Annalisa Pantosti

Evolution of erythromycin resistance in Streptococcus pneumoniae in Italy
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 256-259; doi:10.1093/jac/dkh551 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Elinor Reynolds and Jonathan H. Cove

Enhanced resistance to erythromycin is conferred by the enterococcal msrC determinant in Staphylococcus aureus
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 260-264; doi:10.1093/jac/dkh541 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Francine Mory, Sébastien Fougnot, Christian Rabaud, Hélène Schuhmacher, and Alain Lozniewski

In vitro activities of cefotaxime, vancomycin, quinupristin/dalfopristin, linezolid and other antibiotics alone and in combination against Propionibacterium acnes isolates from central nervous system infections
JAC Advance Access published on December 8, 2004
J. Antimicrob. Chemother. 2005 55: 265-268; doi:10.1093/jac/dkh521 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Clement Mugabe, Ali O. Azghani, and Abdelwahab Omri

Liposome-mediated gentamicin delivery: development and activity against resistant strains of Pseudomonas aeruginosa isolated from cystic fibrosis patients
JAC Advance Access published on December 8, 2004
J. Antimicrob. Chemother. 2005 55: 269-271; doi:10.1093/jac/dkh518 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Andrea Giacometti, Oscar Cirioni, Wojciech Kamysz, Giuseppina D'Amato, Carmela Silvestri, Maria Simona Del Prete, Alberto Licci, Jerzy Lukasiak, and Giorgio Scalise

In vitro activity and killing effect of temporin A on nosocomial isolates of Enterococcus faecalis and interactions with clinically used antibiotics
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 272-274; doi:10.1093/jac/dkh545 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

L. Majoros, G. Kardos, B. Szabó, M. Kovács, and A. Maráz

Fluconazole susceptibility testing of Candida inconspicua clinical isolates: comparison of four methods
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 275-276; doi:10.1093/jac/dkh539 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Jan M. Bell, John D. Turnidge, Matsuhisa Inoue, Shigeru Kohno, Yoichi Hirakata, Yasuo Ono, and Ronald N. Jones

Activity of a peptide deformylase inhibitor LBM415 (NVP PDF-713) tested against recent clinical isolates from Japan
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 276-278; doi:10.1093/jac/dkh547 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Patricia Poeta, Daniela Costa, Jorge Rodrigues, and Carmen Torres

Study of faecal colonization by vanA-containing Enterococcus strains in healthy humans, pets, poultry and wild animals in Portugal
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 278-280; doi:10.1093/jac/dkh549 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

F. Canta, R. Marrone, S. Bonora, A. D'Avolio, M. Sciandra, A. Sinicco, F. G. De Rosa, and G. Di Perri

Pharmacokinetics and hepatotoxicity of lopinavir/ritonavir in non-cirrhotic HIV and hepatitis C virus (HCV) co-infected patients
JAC Advance Access published on January 13, 2005
J. Antimicrob. Chemother. 2005 55: 280-281; doi:10.1093/jac/dkh516 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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