Journal of Antimicrobial Chemotherapy

Leading articles:

Daniel K. Benjamin, Jr, Steven Hirschfeld, Coleen K. Cunningham, and Ross E. McKinney, Jr

Growth as a part of the composite endpoint in paediatric antiretroviral clinical trials
JAC Advance Access published on September 8, 2004
J. Antimicrob. Chemother. 2004 54: 701-703; doi:10.1093/jac/dkh410 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Ricardo M. Santa-Rita, Andréa Henriques-Pons, Helene S. Barbosa, and Solange L. de Castro

Effect of the lysophospholipid analogues edelfosine, ilmofosine and miltefosine against Leishmania amazonensis
JAC Advance Access published on August 25, 2004
J. Antimicrob. Chemother. 2004 54: 704-710; doi:10.1093/jac/dkh380 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Raúl Argüello-García, Maricela Cruz-Soto, Lydia Romero-Montoya, and Guadalupe Ortega-Pierres

Variability and variation in drug susceptibility among Giardia duodenalis isolates and clones exposed to 5-nitroimidazoles and benzimidazoles in vitro
JAC Advance Access published on September 3, 2004
J. Antimicrob. Chemother. 2004 54: 711-721; doi:10.1093/jac/dkh388 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Nicole M. Parrish, Chiew G. Ko, Minerva A. Hughes, Craig A. Townsend, and James D. Dick

Effect of n-octanesulphonylacetamide (OSA) on ATP and protein expression in Mycobacterium bovis BCG
JAC Advance Access published on September 8, 2004
J. Antimicrob. Chemother. 2004 54: 722-729; doi:10.1093/jac/dkh408 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Kaisar A. Talukder, Bijay K. Khajanchi, M. Aminul Islam, Dilip K. Dutta, Zhahirul Islam, Ashrafus Safa, G. Y. Khan, Khorshed Alam, M. A. Hossain, Sarala Malla, S. K. Niyogi, Mustafizur Rahman, Haruo Watanabe, G. Balakrish Nair, and David A. Sack

Genetic relatedness of ciprofloxacin-resistant Shigella dysenteriae type 1 strains isolated in south Asia
JAC Advance Access published on September 3, 2004
J. Antimicrob. Chemother. 2004 54: 730-734; doi:10.1093/jac/dkh425 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

N. Woodford, M. E. Ward, M. E. Kaufmann, J. Turton, E. J. Fagan, D. James, A. P. Johnson, R. Pike, M. Warner, T. Cheasty, A. Pearson, S. Harry, J. B. Leach, A. Loughrey, J. A. Lowes, R. E. Warren, and D. M. Livermore

Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum ß-lactamases in the UK
JAC Advance Access published on September 3, 2004
J. Antimicrob. Chemother. 2004 54: 735-743; doi:10.1093/jac/dkh424 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Robin Bywater, Hubert Deluyker, Erik Deroover, Anno de Jong, Hervé Marion, Malcolm McConville, Tim Rowan, Thomas Shryock, Dale Shuster, Valérie Thomas, Michel Vallé, and John Walters

A European survey of antimicrobial susceptibility among zoonotic and commensal bacteria isolated from food-producing animals
JAC Advance Access published on September 16, 2004
J. Antimicrob. Chemother. 2004 54: 744-754; doi:10.1093/jac/dkh422 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Tetsufumi Koga, Takashi Fukuoka, Norio Doi, Tamako Harasaki, Harumi Inoue, Hitoshi Hotoda, Masayo Kakuta, Yasunori Muramatsu, Naotoshi Yamamura, Misa Hoshi, and Takashi Hirota

Activity of capuramycin analogues against Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium intracellulare in vitro and in vivo
JAC Advance Access published on September 3, 2004
J. Antimicrob. Chemother. 2004 54: 755-760; doi:10.1093/jac/dkh417 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Anjali Sharma, Sadhna Sharma, and G. K. Khuller

Lectin-functionalized poly (lactide-co-glycolide) nanoparticles as oral/aerosolized antitubercular drug carriers for treatment of tuberculosis
JAC Advance Access published on August 25, 2004
J. Antimicrob. Chemother. 2004 54: 761-766; doi:10.1093/jac/dkh411 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Dominique Navas, Jocelyne Caillon, Christele Gras-Le Guen, Cédric Jacqueline, Marie-France Kergueris, Denis Bugnon, and Gilles Potel

Comparison of in vivo intrinsic activity of cefepime and imipenem in a Pseudomonas aeruginosa rabbit endocarditis model: effect of combination with tobramycin simulating human serum pharmacokinetics
JAC Advance Access published on August 18, 2004
J. Antimicrob. Chemother. 2004 54: 767-771; doi:10.1093/jac/dkh381 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M. Werthén, M. Davoudi, A. Sonesson, D. P. Nitsche, M. Mörgelin, K. Blom, and A. Schmidtchen

Pseudomonas aeruginosa-induced infection and degradation of human wound fluid and skin proteins ex vivo are eradicated by a synthetic cationic polymer
JAC Advance Access published on September 8, 2004
J. Antimicrob. Chemother. 2004 54: 772-779; doi:10.1093/jac/dkh407 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Valentin Fuhrmann, Peter Schenk, Walter Jaeger, Salwa Ahmed, and Florian Thalhammer

Pharmacokinetics of moxifloxacin in patients undergoing continuous venovenous haemodiafiltration
JAC Advance Access published on September 3, 2004
J. Antimicrob. Chemother. 2004 54: 780-784; doi:10.1093/jac/dkh421 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

R. S. Autar, J. Ananworanich, W. Apateerapong, J. Sankote, A. Hill, B. Hirschel, D. Cooper, J. Lange, P. Phanuphak, K. Ruxrungtham, and D. Burger

Pharmacokinetic study of saquinavir hard gel caps/ritonavir in HIV-1-infected patients: 1600/100 mg once-daily compared with 2000/100 mg once-daily and 1000/100 mg twice-daily
JAC Advance Access published on August 25, 2004
J. Antimicrob. Chemother. 2004 54: 785-790; doi:10.1093/jac/dkh415 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Åsa Sullivan, Anita Johansson, Bo Svenungsson, and Carl Erik Nord

Effect of Lactobacillus F19 on the emergence of antibiotic-resistant microorganisms in the intestinal microflora
JAC Advance Access published on August 25, 2004
J. Antimicrob. Chemother. 2004 54: 791-797; doi:10.1093/jac/dkh406 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Eric Senneville, Laurence Legout, Michel Valette, Yazdan Yazdanpanah, François Giraud, Eric Beltrand, Guillaume Obert, Luc Dubreuil, Henri Migaud, and Yves Mouton

Risk factors for anaemia in patients on prolonged linezolid therapy for chronic osteomyelitis: a case–control study
JAC Advance Access published on August 25, 2004
J. Antimicrob. Chemother. 2004 54: 798-802; doi:10.1093/jac/dkh409 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. Y. Peleg and M. L. Woods

Continuous and 4 h infusion of amphotericin B: a comparative study involving high-risk haematology patients
JAC Advance Access published on August 12, 2004
J. Antimicrob. Chemother. 2004 54: 803-808; doi:10.1093/jac/dkh403 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Alberto Corona, A. Peter R. Wilson, Mario Grassi, and Mervyn Singer

Prospective audit of bacteraemia management in a university hospital ICU using a general strategy of short-course monotherapy
JAC Advance Access published on September 16, 2004
J. Antimicrob. Chemother. 2004 54: 809-817; doi:10.1093/jac/dkh416 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Venkata G. Meka, Howard S. Gold, Amy Cooke, Lata Venkataraman, George M. Eliopoulos, Robert C. Moellering, Jr, and Stephen G. Jenkins

Reversion to susceptibility in a linezolid-resistant clinical isolate of Staphylococcus aureus
JAC Advance Access published on September 3, 2004
J. Antimicrob. Chemother. 2004 54: 818-820; doi:10.1093/jac/dkh423 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Paul G. Higgins, Hilmar Wisplinghoff, Danuta Stefanik, and Harald Seifert

Selection of topoisomerase mutations and overexpression of adeB mRNA transcripts during an outbreak of Acinetobacter baumannii
JAC Advance Access published on September 8, 2004
J. Antimicrob. Chemother. 2004 54: 821-823; doi:10.1093/jac/dkh427 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

P. Lefèvre, P. Peirs, M. Braibant, M. Fauville-Dufaux, R. Vanhoof, K. Huygen, X.-M. Wang, B. Pogell, Y. Wang, P. Fischer, P. Metz, and J. Content

Antimycobacterial activity of synthetic pamamycins
JAC Advance Access published on August 18, 2004
J. Antimicrob. Chemother. 2004 54: 824-827; doi:10.1093/jac/dkh402 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Katarzyna Szczypa, Ewa Sadowy, Radoslaw Izdebski, and Waleria Hryniewicz

A rapid increase in macrolide resistance in Streptococcus pyogenes isolated in Poland during 1996–2002
JAC Advance Access published on August 25, 2004
J. Antimicrob. Chemother. 2004 54: 828-831; doi:10.1093/jac/dkh420 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brad Spellberg, Thomas Yoo, and Arnold S. Bayer

Reversal of linezolid-associated cytopenias, but not peripheral neuropathy, by administration of vitamin B6
JAC Advance Access published on August 18, 2004
J. Antimicrob. Chemother. 2004 54: 832-835; doi:10.1093/jac/dkh405 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

K. Oberdorfer, S. Swoboda, A. Hamann, U. Baertsch, K. Kusterer, B. Born, T. Hoppe-Tichy, H. K. Geiss, and H. von Baum

Tissue and serum levofloxacin concentrations in diabetic foot infection patients
JAC Advance Access published on September 16, 2004
J. Antimicrob. Chemother. 2004 54: 836-839; doi:10.1093/jac/dkh412 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

José Luis Arredondo-García, Ricardo Figueroa-Damián, Alejandro Rosas, Arturo Jáuregui, Mauricio Corral, Alexis Costa, Roberto Mauricio Merlos, Antonio Ríos-Fabra, Carlos F. Amábile-Cuevas, Gerardo M. Hernández-Oliva, Jorge Olguín, and Oscar Cardeñosa-Guerra on behalf of the uUTI Latin American Study Group

Comparison of short-term treatment regimen of ciprofloxacin versus long-term treatment regimens of trimethoprim/sulfamethoxazole or norfloxacin for uncomplicated lower urinary tract infections: a randomized, multicentre, open-label, prospective study
JAC Advance Access published on September 3, 2004
J. Antimicrob. Chemother. 2004 54: 840-843; doi:10.1093/jac/dkh414 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

P. Ken Gillman

Comment on: Serotonin syndrome due to co-administration of linezolid and venlafaxine
JAC Advance Access published on August 18, 2004
J. Antimicrob. Chemother. 2004 54: 844-845; doi:10.1093/jac/dkh404 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

P. L. Ho, Cindy W. S. Tse, Gannon C. Mak, K. H. Chow, and T. K. Ng

Community-acquired methicillin-resistant Staphylococcus aureus arrives in Hong Kong
JAC Advance Access published on September 8, 2004
J. Antimicrob. Chemother. 2004 54: 845-846; doi:10.1093/jac/dkh426 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Mahbubur Rahman, Shereen Shoma, Harunur Rashid, A. K. Siddique, G. B. Nair, and D. A. Sack

Extended-spectrum ß-lactamase-mediated third-generation cephalosporin resistance in Shigella isolates in Bangladesh
JAC Advance Access published on August 25, 2004
J. Antimicrob. Chemother. 2004 54: 846-847; doi:10.1093/jac/dkh413 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Book reviews:

J. R. Stephenson

Medical Bacteriology. A Practical Approach
J. Antimicrob. Chemother. 2004 54: 848; doi:10.1093/jac/dkh418 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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