Journal of Antimicrobial Chemotherapy

Leading articles:

Javier Rojo and Rafael Delgado

Glycodendritic structures: promising new antiviral drugs
JAC Advance Access published on August 12, 2004
J. Antimicrob. Chemother. 2004 54: 579-581; doi:10.1093/jac/dkh399 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Kathryn L. Springer and Adriana Weinberg

Cytomegalovirus infection in the era of HAART: fewer reactivations and more immunity
JAC Advance Access published on July 28, 2004
J. Antimicrob. Chemother. 2004 54: 582-586; doi:10.1093/jac/dkh396 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Reviews:

Jose R. Arribas

The rise and fall of triple nucleoside reverse transcriptase inhibitor (NRTI) regimens
JAC Advance Access published on July 28, 2004
J. Antimicrob. Chemother. 2004 54: 587-592; doi:10.1093/jac/dkh384 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Giovanni Di Perri and Stefano Bonora

Which agents should we use for the treatment of multidrug-resistant Mycobacterium tuberculosis?
JAC Advance Access published on July 28, 2004
J. Antimicrob. Chemother. 2004 54: 593-602; doi:10.1093/jac/dkh377 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Antonella Lupetti, Carlo P. J. M. Brouwer, Heleen E. C. Dogterom-Ballering, Sonia Senesi, Mario Campa, Jaap T. van Dissel, and Peter H. Nibbering

Release of calcium from intracellular stores and subsequent uptake by mitochondria are essential for the candidacidal activity of an N-terminal peptide of human lactoferrin
JAC Advance Access published on July 28, 2004
J. Antimicrob. Chemother. 2004 54: 603-608; doi:10.1093/jac/dkh385 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Mirjam Walker, Jean François Rossignol, Paul Torgerson, and Andrew Hemphill

In vitro effects of nitazoxanide on Echinococcus granulosus protoscoleces and metacestodes
JAC Advance Access published on July 28, 2004
J. Antimicrob. Chemother. 2004 54: 609-616; doi:10.1093/jac/dkh386 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Shazad Mushtaq, Marina Warner, Alan P. Johnson, and David M. Livermore

Activity of dalbavancin against staphylococci and streptococci, assessed by BSAC and NCCLS agar dilution methods
JAC Advance Access published on August 20, 2004
J. Antimicrob. Chemother. 2004 54: 617-620; doi:10.1093/jac/dkh401 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

L. P. Randall, S. W. Cooles, L. J. V. Piddock, and M. J. Woodward

Effect of triclosan or a phenolic farm disinfectant on the selection of antibiotic-resistant Salmonella enterica
JAC Advance Access published on July 21, 2004
J. Antimicrob. Chemother. 2004 54: 621-627; doi:10.1093/jac/dkh376 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

C. J. Munday, G. M. Whitehead, N. J. Todd, M. Campbell, and P. M. Hawkey

Predominance and genetic diversity of community- and hospital-acquired CTX-M extended-spectrum ß-lactamases in York, UK
JAC Advance Access published on August 4, 2004
J. Antimicrob. Chemother. 2004 54: 628-633; doi:10.1093/jac/dkh397 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

C. De Champs, C. Chanal, D. Sirot, R. Baraduc, J. P. Romaszko, R. Bonnet, A. Plaidy, M. Boyer, E. Carroy, M. C. Gbadamassi, S. Laluque, O. Oules, M. C. Poupart, M. Villemain, and J. Sirot

Frequency and diversity of Class A extended-spectrum ß-lactamases in hospitals of the Auvergne, France: a 2 year prospective study
JAC Advance Access published on July 28, 2004
J. Antimicrob. Chemother. 2004 54: 634-639; doi:10.1093/jac/dkh395 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Delphine Croisier, Manuel Etienne, Lionel Piroth, Emilie Bergoin, Catherine Lequeu, Henri Portier, and Pascal Chavanet

In vivo pharmacodynamic efficacy of gatifloxacin against Streptococcus pneumoniae in an experimental model of pneumonia: impact of the low levels of fluoroquinolone resistance on the enrichment of resistant mutants
JAC Advance Access published on August 18, 2004
J. Antimicrob. Chemother. 2004 54: 640-647; doi:10.1093/jac/dkh393 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Danuta Kruszewska, Hans-Georg Sahl, Gabriele Bierbaum, Ulrike Pag, Sean O. Hynes, and Åsa Ljungh

Mersacidin eradicates methicillin-resistant Staphylococcus aureus (MRSA) in a mouse rhinitis model
JAC Advance Access published on July 28, 2004
J. Antimicrob. Chemother. 2004 54: 648-653; doi:10.1093/jac/dkh387 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Andrea Giacometti, Roberto Ghiselli, Oscar Cirioni, Federico Mocchegiani, Giuseppina D'Amato, Fiorenza Orlando, Valerio Sisti, Wojciech Kamysz, Carmela Silvestri, Piotr Naldoski, Jerzy Lukasiak, Vittorio Saba, and Giorgio Scalise

Therapeutic efficacy of the magainin analogue MSI-78 in different intra-abdominal sepsis rat models
JAC Advance Access published on August 4, 2004
J. Antimicrob. Chemother. 2004 54: 654-660; doi:10.1093/jac/dkh390 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Samuel Coenen, Paul Van Royen, Barbara Michiels, and Joke Denekens

Optimizing antibiotic prescribing for acute cough in general practice: a cluster-randomized controlled trial
JAC Advance Access published on July 28, 2004
J. Antimicrob. Chemother. 2004 54: 661-672; doi:10.1093/jac/dkh374 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Yanina Balabanova, Ivan Fedorin, Sergey Kuznetsov, Catriona Graham, Michael Ruddy, Rifat Atun, Richard Coker, and Francis Drobniewski

Antimicrobial prescribing patterns for respiratory diseases including tuberculosis in Russia: a possible role in drug resistance?
JAC Advance Access published on August 18, 2004
J. Antimicrob. Chemother. 2004 54: 673-679; doi:10.1093/jac/dkh383 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

David A. Boyd, Pamela Kibsey, Diane Roscoe, and Michael R. Mulvey on behalf of the Canadian Nosocomial Infection Surveillance Program

Enterococcus faecium N03-0072 carries a new VanD-type vancomycin resistance determinant: characterization of the VanD5 operon
JAC Advance Access published on August 12, 2004
J. Antimicrob. Chemother. 2004 54: 680-683; doi:10.1093/jac/dkh391 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M. Shahid, Abida Malik, Mithlesh Agrawal, and Sanjay Singhal

Phenotypic detection of extended-spectrum and AmpC ß-lactamases by a new spot-inoculation method and modified three-dimensional extract test: comparison with the conventional three-dimensional extract test
JAC Advance Access published on August 4, 2004
J. Antimicrob. Chemother. 2004 54: 684-687; doi:10.1093/jac/dkh389 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

L. P. Randall, S. W. Cooles, L. J. V. Piddock, and M. J. Woodward

Mutant prevention concentrations of ciprofloxacin and enrofloxacin for Salmonella enterica
JAC Advance Access published on July 8, 2004
J. Antimicrob. Chemother. 2004 54: 688-691; doi:10.1093/jac/dkh360 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

Peter Silley and Robrecht Froyman

Comment on: Effect of a 5 day enrofloxacin treatment on Salmonella enterica serotype Typhimurium DT104 in the pig
JAC Advance Access published on August 12, 2004
J. Antimicrob. Chemother. 2004 54: 692-693; doi:10.1093/jac/dkh370 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Anne A. Delsol, Martin J. Woodward, and John M. Roe

Reply
JAC Advance Access published on August 12, 2004
J. Antimicrob. Chemother. 2004 54: 693-694; doi:10.1093/jac/dkh400 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

David A. Green

There are no paradoxes of adherence and drug resistance to HIV antiretroviral therapy
JAC Advance Access published on July 28, 2004
J. Antimicrob. Chemother. 2004 54: 694; doi:10.1093/jac/dkh378 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

David R. Bangsberg, Andrew R. Moss, and Steven G. Deeks

Reply
JAC Advance Access published on July 28, 2004
J. Antimicrob. Chemother. 2004 54: 694-695; doi:10.1093/jac/dkh392 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Ahmed Hamouda and Sebastian G. B. Amyes

Novel gyrA and parC point mutations in two strains of Acinetobacter baumannii resistant to ciprofloxacin
JAC Advance Access published on July 28, 2004
J. Antimicrob. Chemother. 2004 54: 695-696; doi:10.1093/jac/dkh368 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Paul Seaman, Martin Day, A. Denver Russell, and Dietmar Ochs

Susceptibility of capsular Staphylococcus aureus strains to some antibiotics, triclosan and cationic biocides
JAC Advance Access published on July 28, 2004
J. Antimicrob. Chemother. 2004 54: 696-698; doi:10.1093/jac/dkh382 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

David Felmingham, Jemma Shackcloth, and Glenn Tillotson

BSAC Respiratory Resistance Surveillance Programme (2002–2003): comparative susceptibility of Streptococcus pneumoniae, cultured from patients in Great Britain and Ireland with community-acquired lower respiratory tract infection, to gemifloxacin
JAC Advance Access published on August 4, 2004
J. Antimicrob. Chemother. 2004 54: 698-699; doi:10.1093/jac/dkh394 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Anton Y. Peleg, Clare Franklin, Jan Bell, and Denis W. Spelman

Emergence of IMP-4 metallo-ß-lactamase in a clinical isolate from Australia
JAC Advance Access published on July 28, 2004
J. Antimicrob. Chemother. 2004 54: 699-700; doi:10.1093/jac/dkh398 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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