Journal of Antimicrobial Chemotherapy

Leading articles:

Golo Ahlenstiel, Rainer P. Woitas, Jürgen Rockstroh, and Ulrich Spengler

CC-chemokine receptor 5 (CCR5) in hepatitis C—at the crossroads of the antiviral immune response?
JAC Advance Access published on May 5, 2004
J. Antimicrob. Chemother. 2004 53: 895-898; doi:10.1093/jac/dkh239 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Conan MacDougall and B. Joseph Guglielmo

Pharmacokinetics of valaciclovir
JAC Advance Access published on May 12, 2004
J. Antimicrob. Chemother. 2004 53: 899-901; doi:10.1093/jac/dkh244 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Lance R. Peterson and Axel Dalhoff

Towards targeted prescribing: will the cure for antimicrobial resistance be specific, directed therapy through improved diagnostic testing?
JAC Advance Access published on April 29, 2004
J. Antimicrob. Chemother. 2004 53: 902-905; doi:10.1093/jac/dkh187 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Reviews:

Emma L. Snary, Louise A. Kelly, Helen C. Davison, Christopher J. Teale, and Marion Wooldridge

Antimicrobial resistance: a microbial risk assessment perspective
JAC Advance Access published on April 21, 2004
J. Antimicrob. Chemother. 2004 53: 906-917; doi:10.1093/jac/dkh182 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ralf René Reinert

Clinical efficacy of ketolides in the treatment of respiratory tract infections
JAC Advance Access published on April 29, 2004
J. Antimicrob. Chemother. 2004 53: 918-927; doi:10.1093/jac/dkh169 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Elizabeth S. R. Darley and Alasdair P. MacGowan

Antibiotic treatment of Gram-positive bone and joint infections
JAC Advance Access published on April 29, 2004
J. Antimicrob. Chemother. 2004 53: 928-935; doi:10.1093/jac/dkh191 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Maria Winnock, Dominique Salmon-Céron, François Dabis, and Geneviève Chêne

Interaction between HIV-1 and HCV infections: towards a new entity?
JAC Advance Access published on April 29, 2004
J. Antimicrob. Chemother. 2004 53: 936-946; doi:10.1093/jac/dkh200 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Ashraf M. Ahmed, Tomoko Nakagawa, Eiji Arakawa, Thandavarayan Ramamurthy, Sumio Shinoda, and Tadashi Shimamoto

New aminoglycoside acetyltransferase gene, aac(3)-Id, in a class 1 integron from a multiresistant strain of Vibrio fluvialis isolated from an infant aged 6 months
JAC Advance Access published on April 29, 2004
J. Antimicrob. Chemother. 2004 53: 947-951; doi:10.1093/jac/dkh221 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Fiona O’Halloran, Brigid Lucey, Bartley Cryan, Tom Buckley, and Séamus Fanning

Molecular characterization of class 1 integrons from Irish thermophilic Campylobacter spp.
JAC Advance Access published on May 5, 2004
J. Antimicrob. Chemother. 2004 53: 952-957; doi:10.1093/jac/dkh193 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Virve I. Enne, Peter M. Bennett, David M. Livermore, and Lucinda M. C. Hall

Enhancement of host fitness by the sul2-coding plasmid p9123 in the absence of selective pressure
JAC Advance Access published on April 21, 2004
J. Antimicrob. Chemother. 2004 53: 958-963; doi:10.1093/jac/dkh217 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ashfaque Hossain, Mark D. Reisbig, and Nancy D. Hanson

Plasmid-encoded functions compensate for the biological cost of AmpC overexpression in a clinical isolate of Salmonella typhimurium
JAC Advance Access published on May 12, 2004
J. Antimicrob. Chemother. 2004 53: 964-970; doi:10.1093/jac/dkh240 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M. C. Bopape, H. C. Steel, R. Cockeran, N. M. Matlola, P. B. Fourie, and R. Anderson

Antimicrobial activity of clofazimine is not dependent on mycobacterial C-type phospholipases
JAC Advance Access published on April 29, 2004
J. Antimicrob. Chemother. 2004 53: 971-974; doi:10.1093/jac/dkh215 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jacqueline F. L. Fryer, Paul D. Griffiths, Vincent C. Emery, and Duncan A. Clark

Susceptibility of porcine cytomegalovirus to antiviral drugs
JAC Advance Access published on April 29, 2004
J. Antimicrob. Chemother. 2004 53: 975-980; doi:10.1093/jac/dkh231 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Sandra Prior, Bruno Gander, Concepción Lecároz, Juan M. Irache, and Carlos Gamazo

Gentamicin-loaded microspheres for reducing the intracellular Brucella abortus load in infected monocytes
JAC Advance Access published on April 21, 2004
J. Antimicrob. Chemother. 2004 53: 981-988; doi:10.1093/jac/dkh227 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Lauren M. Junker and Anthony G. Hay

Effects of triclosan incorporation into ABS plastic on biofilm communities
JAC Advance Access published on April 29, 2004
J. Antimicrob. Chemother. 2004 53: 989-996; doi:10.1093/jac/dkh196 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Wondwossen A. Gebreyes, Siddhartha Thakur, Peter R. Davies, Julie A. Funk, and Craig Altier

Trends in antimicrobial resistance, phage types and integrons among Salmonella serotypes from pigs, 1997–2000
JAC Advance Access published on May 18, 2004
J. Antimicrob. Chemother. 2004 53: 997-1003; doi:10.1093/jac/dkh247 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Paul Ebner, Kimberly Garner, and Alan Mathew

Class 1 integrons in various Salmonella enterica serovars isolated from animals and identification of genomic island SGI1 in Salmonella enterica var. Meleagridis
JAC Advance Access published on April 29, 2004
J. Antimicrob. Chemother. 2004 53: 1004-1009; doi:10.1093/jac/dkh192 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Margaret L. Heginbothom, J. T. Magee, Joanna L. Bell, F. D. J. Dunstan, A. J. Howard, Sharon L. Hillier, S. R. Palmer, and B. W. Mason on behalf of the Welsh Antibiotic Study Group

Laboratory testing policies and their effects on routine surveillance of community antimicrobial resistance
JAC Advance Access published on April 21, 2004
J. Antimicrob. Chemother. 2004 53: 1010-1017; doi:10.1093/jac/dkh229 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Rosy Reynolds, Nicola Potz, Melissa Colman, Andrea Williams, David Livermore, and Alasdair MacGowan on behalf of the BSAC Extended Working Party on Bacteraemia Resistance Surveillance

Antimicrobial susceptibility of the pathogens of bacteraemia in the UK and Ireland 2001–2002: the BSAC Bacteraemia Resistance Surveillance Programme
JAC Advance Access published on May 5, 2004
J. Antimicrob. Chemother. 2004 53: 1018-1032; doi:10.1093/jac/dkh232 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jesús Oteo, Fernando Baquero, Ana Vindel, and José Campos on behalf of the Spanish members of The European Antimicrobial Resistance Surveillance System (EARSS)

Antibiotic resistance in 3113 blood isolates of Staphylococcus aureus in 40 Spanish hospitals participating in the European Antimicrobial Resistance Surveillance System (2000–2002)
JAC Advance Access published on May 5, 2004
J. Antimicrob. Chemother. 2004 53: 1033-1038; doi:10.1093/jac/dkh214 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Laura M. Koeth, Caryn E. Good, Peter C. Appelbaum, Ellie J. C. Goldstein, Arne C. Rodloff, Marina Claros, and Luc J. Dubreuil

Surveillance of susceptibility patterns in 1297 European and US anaerobic and capnophilic isolates to co-amoxiclav and five other antimicrobial agents
JAC Advance Access published on May 5, 2004
J. Antimicrob. Chemother. 2004 53: 1039-1044; doi:10.1093/jac/dkh248 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M. J. O. Toledo, M. T. Bahia, V. M. Veloso, C. M. Carneiro, G. L. L. Machado-Coelho, C. F. Alves, H. R. Martins, R. E. Cruz, W. L. Tafuri, and M. Lana

Effects of specific treatment on parasitological and histopathological parameters in mice infected with different Trypanosoma cruzi clonal genotypes
JAC Advance Access published on April 21, 2004
J. Antimicrob. Chemother. 2004 53: 1045-1053; doi:10.1093/jac/dkh224 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

H. Wu, Z. Song, M. Hentzer, J. B. Andersen, S. Molin, M. Givskov, and N. Høiby

Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice
JAC Advance Access published on April 29, 2004
J. Antimicrob. Chemother. 2004 53: 1054-1061; doi:10.1093/jac/dkh223 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Laurence Senn, Bernard Burnand, Patrick Francioli, and Giorgio Zanetti

Improving appropriateness of antibiotic therapy: randomized trial of an intervention to foster reassessment of prescription after 3 days
JAC Advance Access published on May 5, 2004
J. Antimicrob. Chemother. 2004 53: 1062-1067; doi:10.1093/jac/dkh236 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

S. Capilla, J. Ruiz, P. Goñi, J. Castillo, M. C. Rubio, M. T. Jiménez de Anta, R. Gómez-Lus, and J. Vila

Characterization of the molecular mechanisms of quinolone resistance in Yersinia enterocolitica O:3 clinical isolates
JAC Advance Access published on April 29, 2004
J. Antimicrob. Chemother. 2004 53: 1068-1071; doi:10.1093/jac/dkh225 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Indrajit Sinha and Thomas Dick

Role for malonyl coenzyme A:acyl carrier protein transacylase (MCAT) in the growth-inhibitory effect of the calmodulin antagonist trifluoperazine in Mycobacterium bovis BCG
JAC Advance Access published on May 18, 2004
J. Antimicrob. Chemother. 2004 53: 1072-1075; doi:10.1093/jac/dkh241 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Sarah Underwood and Matthew B. Avison

Citrobacter koseri and Citrobacter amalonaticus isolates carry highly divergent ß-lactamase genes despite having high levels of biochemical similarity and 16S rRNA sequence homology
JAC Advance Access published on May 5, 2004
J. Antimicrob. Chemother. 2004 53: 1076-1080; doi:10.1093/jac/dkh235 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

K. A. Hammer, C. F. Carson, and T. V. Riley

Antifungal effects of Melaleuca alternifolia (tea tree) oil and its components on Candida albicans, Candida glabrata and Saccharomyces cerevisiae
JAC Advance Access published on May 12, 2004
J. Antimicrob. Chemother. 2004 53: 1081-1085; doi:10.1093/jac/dkh243 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Guillermo Garcia-Effron, Alicia Gomez-Lopez, Emilia Mellado, Araceli Monzon, Juan L. Rodriguez-Tudela, and Manuel Cuenca-Estrella

In vitro activity of terbinafine against medically important non-dermatophyte species of filamentous fungi
JAC Advance Access published on April 21, 2004
J. Antimicrob. Chemother. 2004 53: 1086-1089; doi:10.1093/jac/dkh228 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. Alhambra, J. A. Cuadros, J. Cacho, J. L. Gómez-Garcés, and J. I. Alós

In vitro susceptibility of recent antibiotic-resistant urinary pathogens to ertapenem and 12 other antibiotics
JAC Advance Access published on April 29, 2004
J. Antimicrob. Chemother. 2004 53: 1090-1094; doi:10.1093/jac/dkh218 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Young Uh, Dong Hoon Shin, In Ho Jang, Gyu Yel Hwang, Mi Kyung Lee, Kap Jun Yoon, and Hyo Youl Kim

Antimicrobial susceptibility patterns and macrolide resistance genes of viridans group streptococci from blood cultures in Korea
JAC Advance Access published on April 29, 2004
J. Antimicrob. Chemother. 2004 53: 1095-1097; doi:10.1093/jac/dkh219 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Chinedum P. Babalola, Charles H. Nightingale, and David P. Nicolau

Adjunctive efficacy of granulocyte colony-stimulating factor on treatment of Pseudomonas aeruginosa pneumonia in neutropenic and non-neutropenic hosts
JAC Advance Access published on May 5, 2004
J. Antimicrob. Chemother. 2004 53: 1098-1100; doi:10.1093/jac/dkh237 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

L. Törmäkangas, E. Saario, D. Bem David, A. Bryskier, M. Leinonen, and P. Saikku

Treatment of acute Chlamydia pneumoniae infection with telithromycin in C57BL/6J mice
JAC Advance Access published on April 29, 2004
J. Antimicrob. Chemother. 2004 53: 1101-1104; doi:10.1093/jac/dkh213 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Issam Raad, Ray Hachem, and Hend Hanna

Relationship between myalgias/arthralgias occurring in patients receiving quinupristin/dalfopristin and biliary dysfunction
JAC Advance Access published on May 5, 2004
J. Antimicrob. Chemother. 2004 53: 1105-1108; doi:10.1093/jac/dkh234 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Dominique L. Monnet, Sigvard Mölstad, and Otto Cars

Defined daily doses of antimicrobials reflect antimicrobial prescriptions in ambulatory care
JAC Advance Access published on April 29, 2004
J. Antimicrob. Chemother. 2004 53: 1109-1111; doi:10.1093/jac/dkh230 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

Julieanne M. Bostock, Ian Geary, Adrian Eley, and Ian Chopra

Mecillinam has potent in vitro activity against Chlamydophila pneumoniae ATCC VR1310
JAC Advance Access published on April 29, 2004
J. Antimicrob. Chemother. 2004 53: 1112; doi:10.1093/jac/dkh233 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

L. Romero, L. López, L. Martínez-Martínez, B. Guerra, J. R. Hernández, and A. Pascual

Characterization of the first CTX-M-14-producing Salmonella enterica serotype Enteritidis isolate
JAC Advance Access published on May 18, 2004
J. Antimicrob. Chemother. 2004 53: 1113-1114; doi:10.1093/jac/dkh246 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Frédéric Frippiat, Christelle Bergiers, Claire Michel, Jean-Pierre Dujardin, and Geneviève Derue

Severe bilateral optic neuritis associated with prolonged linezolid therapy
JAC Advance Access published on April 29, 2004
J. Antimicrob. Chemother. 2004 53: 1114-1115; doi:10.1093/jac/dkh199 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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