Journal of Antimicrobial Chemotherapy

Leading articles:

Beverley C. Millar and John E. Moore

Antibiotic prophylaxis, body piercing and infective endocarditis
JAC Advance Access published on December 19, 2003
J. Antimicrob. Chemother. 2004 53: 123-126; doi:10.1093/jac/dkh034 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Louis Bernard, Pierre Hoffmeyer, Mathieu Assal, Pierre Vaudaux, Jacques Schrenzel, and Daniel Lew

Trends in the treatment of orthopaedic prosthetic infections
JAC Advance Access published on December 19, 2003
J. Antimicrob. Chemother. 2004 53: 127-129; doi:10.1093/jac/dkh033 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ben de Pauw

Preventative use of antifungal drugs in patients treated for cancer
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 130-132; doi:10.1093/jac/dkh085 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

John Oxford, Shobana Balasingam, and Rob Lambkin

A new millennium conundrum: how to use a powerful class of influenza anti-neuraminidase drugs (NAIs) in the community
JAC Advance Access published on December 19, 2003
J. Antimicrob. Chemother. 2004 53: 133-136; doi:10.1093/jac/dkh037 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Hans-Ulrich Bernard

Established and potential strategies against papillomavirus infections
JAC Advance Access published on January 7, 2004
J. Antimicrob. Chemother. 2004 53: 137-139; doi:10.1093/jac/dkh023 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Elisabeta Vergu, Alain Mallet, and Jean-Louis Golmard

Available clinical markers of treatment outcome integrated in mathematical models to guide therapy in HIV infection
JAC Advance Access published on December 19, 2003
J. Antimicrob. Chemother. 2004 53: 140-143; doi:10.1093/jac/dkh024 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Reviews:

Ian Morrissey and Glenn Tillotson

Activity of gemifloxacin against Streptococcus pneumoniae and Haemophilus influenzae
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 144-148; doi:10.1093/jac/dkh092 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

C. Muller-Serieys, J. Andrews, F. Vacheron, and C. Cantalloube

Tissue kinetics of telithromycin, the first ketolide antibacterial
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 149-157; doi:10.1093/jac/dkh068 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

J. Blum, P. Desjeux, E. Schwartz, B. Beck, and C. Hatz

Treatment of cutaneous leishmaniasis among travellers
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 158-166; doi:10.1093/jac/dkh058 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Oleg Krut, Herdis Sommer, and Martin Krönke

Antibiotic-induced persistence of cytotoxic Staphylococcus aureus in non-phagocytic cells
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 167-173; doi:10.1093/jac/dkh076 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Peter Lanbeck, Inga Odenholt, and Kristian Riesbeck

Dicloxacillin and erythromycin at high concentrations increase ICAM-1 expression by endothelial cells: a possible factor in the pathogenesis of infusion phlebitis
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 174-179; doi:10.1093/jac/dkh056 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Harriet G. MacLehose, Peter Gilbert, and David G. Allison

Biofilms, homoserine lactones and biocide susceptibility
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 180-184; doi:10.1093/jac/dkh090 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Michael J. Hearn and Michael H. Cynamon

Design and synthesis of antituberculars: preparation and evaluation against Mycobacterium tuberculosis of an isoniazid Schiff base
JAC Advance Access published on December 19, 2003
J. Antimicrob. Chemother. 2004 53: 185-191; doi:10.1093/jac/dkh041 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Akos Somoskovi, Mary Margaret Wade, Zhonghe Sun, and Ying Zhang

Iron enhances the antituberculous activity of pyrazinamide
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 192-196; doi:10.1093/jac/dkh042 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Matthew B. Avison, Pannika Niumsup, Kurshid Nurmahomed, Timothy R. Walsh, and Peter M. Bennett

Role of the ‘cre/blr-tag’ DNA sequence in regulation of gene expression by the Aeromonas hydrophila ß-lactamase regulator, BlrA
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 197-202; doi:10.1093/jac/dkh077 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

V. I. Enne, A. A. Delsol, J. M. Roe, and P. M. Bennett

Rifampicin resistance and its fitness cost in Enterococcus faecium
JAC Advance Access published on December 19, 2003
J. Antimicrob. Chemother. 2004 53: 203-207; doi:10.1093/jac/dkh044 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

L. P. Randall, S. W. Cooles, M. K. Osborn, L. J. V. Piddock, and M. J. Woodward

Antibiotic resistance genes, integrons and multiple antibiotic resistance in thirty-five serotypes of Salmonella enterica isolated from humans and animals in the UK
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 208-216; doi:10.1093/jac/dkh070 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Mi-Kyung Lee, Laura E. Williams, David W. Warnock, and Beth A. Arthington-Skaggs

Drug resistance genes and trailing growth in Candida albicans isolates
JAC Advance Access published on December 19, 2003
J. Antimicrob. Chemother. 2004 53: 217-224; doi:10.1093/jac/dkh040 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Masatomo Hirasawa and Kazuko Takada

Multiple effects of green tea catechin on the antifungal activity of antimycotics against Candida albicans
JAC Advance Access published on December 19, 2003
J. Antimicrob. Chemother. 2004 53: 225-229; doi:10.1093/jac/dkh046 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

U. Pag, M. Oedenkoven, N. Papo, Z. Oren, Y. Shai, and H.-G. Sahl

In vitro activity and mode of action of diastereomeric antimicrobial peptides against bacterial clinical isolates
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 230-239; doi:10.1093/jac/dkh083 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Carlos J. Minahk, Fernando Dupuy, and Roberto D. Morero

Enhancement of antibiotic activity by sub-lethal concentrations of enterocin CRL35
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 240-246; doi:10.1093/jac/dkh079 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. Athamna, M. Massalha, M. Athamna, A. Nura, B. Medlej, I. Ofek, D. Bast, and E. Rubinstein

In vitro susceptibility of Bacillus anthracis to various antibacterial agents and their time–kill activity
JAC Advance Access published on December 19, 2003
J. Antimicrob. Chemother. 2004 53: 247-251; doi:10.1093/jac/dkh016 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Hans-Jörg Linde and Norbert Lehn

Mutant prevention concentration of nalidixic acid, ciprofloxacin, clinafloxacin, levofloxacin, norfloxacin, ofloxacin, sparfloxacin or trovafloxacin for Escherichia coli under different growth conditions
JAC Advance Access published on December 19, 2003
J. Antimicrob. Chemother. 2004 53: 252-257; doi:10.1093/jac/dkh036 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

R. N. Jones, K. A. Gordon, and D. J. Biedenbach

Comparisons of the in vitro susceptibility testing results for garenoxacin using six different national methods: report from the garenoxacin international bridging study
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 258-265; doi:10.1093/jac/dkh060 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Hidetake Esaki, Ayako Morioka, Kanako Ishihara, Akemi Kojima, Sanae Shiroki, Yutaka Tamura, and Toshio Takahashi

Antimicrobial susceptibility of Salmonella isolated from cattle, swine and poultry (2001–2002): report from the Japanese Veterinary Antimicrobial Resistance Monitoring Program
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 266-270; doi:10.1093/jac/dkh081 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Surbhi Malhotra-Kumar, Christine Lammens, An Martel, Cecile Mallentjer, Sabine Chapelle, Jeanine Verhoeven, Monique Wijdooghe, Freddy Haesebrouck, and Herman Goossens

Oropharyngeal carriage of macrolide-resistant viridans group streptococci: a prevalence study among healthy adults in Belgium
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 271-276; doi:10.1093/jac/dkh026 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Mario Tumbarello, Rita Citton, Teresa Spanu, Maurizio Sanguinetti, Lucio Romano, Giovanni Fadda, and Roberto Cauda

ESBL-producing multidrug-resistant Providencia stuartii infections in a university hospital
JAC Advance Access published on December 19, 2003
J. Antimicrob. Chemother. 2004 53: 277-282; doi:10.1093/jac/dkh047 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Shunji Takakura, Naoko Fujihara, Takashi Saito, Toyoichiro Kudo, Yoshitsugu Iinuma, Satoshi Ichiyama, and the Japan Invasive Mycosis Surveillance Study Group

National surveillance of species distribution in blood isolates of Candida species in Japan and their susceptibility to six antifungal agents including voriconazole and micafungin
JAC Advance Access published on December 19, 2003
J. Antimicrob. Chemother. 2004 53: 283-289; doi:10.1093/jac/dkh053 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Alan H. Mutnick, Paul R. Rhomberg, Helio S. Sader, and Ronald N. Jones

Antimicrobial usage and resistance trend relationships from the MYSTIC Programme in North America (1999–2001)
JAC Advance Access published on January 7, 2004
J. Antimicrob. Chemother. 2004 53: 290-296; doi:10.1093/jac/dkh039 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Chonghua Li, David P. Nicolau, Philip D. Lister, Richard Quintiliani, and Charles H. Nightingale

Pharmacodynamic study of ß-lactams alone and in combination with ß-lactamase inhibitors against Pseudomonas aeruginosa possessing an inducible ß-lactamase
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 297-304; doi:10.1093/jac/dkh057 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

L. Flatz, M. Cottagnoud, F. Kühn, J. Entenza, A. Stucki, and P. Cottagnoud

Ceftriaxone acts synergistically with levofloxacin in experimental meningitis and reduces levofloxacin-induced resistance in penicillin-resistant pneumococci
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 305-310; doi:10.1093/jac/dkh082 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Koji Takemoto, Yutaka Yamamoto, Yutaka Ueda, Yoshihiro Sumita, Koichiro Yoshida, and Yoshihito Niki

Comparative studies on the efficacy of AmBisome and Fungizone in a mouse model of disseminated aspergillosis
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 311-317; doi:10.1093/jac/dkh055 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Reiner Schaumann, Rosemarie Blatz, Joerg Beer, Grit Ackermann, and Arne C. Rodloff

Effect of moxifloxacin versus imipenem/cilastatin treatment on the mortality of mice infected intravenously with different strains of Bacteroides fragilis and Escherichia coli
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 318-324; doi:10.1093/jac/dkh089 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Dinesh Saralaya, Daniel G. Peckham, Bill Hulme, Caroline M. Tobin, Miles Denton, Steve Conway, and Christine Etherington

Serum and sputum concentrations following the oral administration of linezolid in adult patients with cystic fibrosis
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 325-328; doi:10.1093/jac/dkh072 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

E. Bertazzoni Minelli, A. Benini, B. Magnan, and P. Bartolozzi

Release of gentamicin and vancomycin from temporary human hip spacers in two-stage revision of infected arthroplasty
JAC Advance Access published on December 19, 2003
J. Antimicrob. Chemother. 2004 53: 329-334; doi:10.1093/jac/dkh032 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Mark Wilcox, Dilip Nathwani, and Matthew Dryden

Linezolid compared with teicoplanin for the treatment of suspected or proven Gram-positive infections
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 335-344; doi:10.1093/jac/dkh088 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jorge A. Cepeda, Tony Whitehouse, Ben Cooper, Janeane Hails, Karen Jones, Felicia Kwaku, Lee Taylor, Samantha Hayman, Steven Shaw, Christopher Kibbler, Robert Shulman, Mervyn Singer, and A. Peter R. Wilson

Linezolid versus teicoplanin in the treatment of Gram-positive infections in the critically ill: a randomized, double-blind, multicentre study
JAC Advance Access published on January 7, 2004
J. Antimicrob. Chemother. 2004 53: 345-355; doi:10.1093/jac/dkh048 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Maurizio Zazzi, Laura Romano, Giulietta Venturi, Robert W. Shafer, Caroline Reid, Federico Dal Bello, Cristina Parolin, Giorgio Palù, and Pier E. Valensin

Comparative evaluation of three computerized algorithms for prediction of antiretroviral susceptibility from HIV type 1 genotype
JAC Advance Access published on December 19, 2003
J. Antimicrob. Chemother. 2004 53: 356-360; doi:10.1093/jac/dkh021 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Antimicrobial Practice:

Hanneke B. M. Otters, Johannes C. van der Wouden, Francois G. Schellevis, Lisette W. A. van Suijlekom-Smit, and Bart W. Koes

Trends in prescribing antibiotics for children in Dutch general practice
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 361-366; doi:10.1093/jac/dkh062 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Elena Ortega, M. Antonia Escobar, José Juan Gaforio, Ignacio Algarra, and Gerardo Alvarez de Cienfuegos

Modification of phagocytosis and cytokine production in peritoneal and splenic murine cells by erythromycin A, azithromycin and josamycin
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 367-370; doi:10.1093/jac/dkh069 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

F. Levy and E. S. Walker

BRO ß-lactamase alleles, antibiotic resistance and a test of the BRO-1 selective replacement hypothesis in Moraxella catarrhalis
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 371-374; doi:10.1093/jac/dkh063 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

J.-Y. Chen, Chang-Phone Fung, Feng-Yee Chang, Li-Yueh Huang, Jen-Chang Chang, and L. K. Siu

Mutations of the rpoB gene in rifampicin-resistant Streptococcus pneumoniae in Taiwan
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 375-378; doi:10.1093/jac/dkh073 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Stefan Schwarz, Corinna Kehrenberg, Sarah A. Salmon, and Jeffrey L. Watts

In vitro activities of spectinomycin and comparator agents against Pasteurella multocida and Mannheimia haemolytica from respiratory tract infections of cattle
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 379-382; doi:10.1093/jac/dkh059 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Hanadi Lamfon, Stephen R. Porter, Michael McCullough, and Jonathan Pratten

Susceptibility of Candida albicans biofilms grown in a constant depth film fermentor to chlorhexidine, fluconazole and miconazole: a longitudinal study
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 383-385; doi:10.1093/jac/dkh071 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Elias K. Manavathu, Mayur S. Ramesh, Inthumathi Baskaran, Latha T. Ganesan, and Pranatharthi H. Chandrasekar

A comparative study of the post-antifungal effect (PAFE) of amphotericin B, triazoles and echinocandins on Aspergillus fumigatus and Candida albicans
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 386-389; doi:10.1093/jac/dkh066 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

C. Padilla, O. Lobos, P. Brevis, P. Abaca, and E. Hubert

In vitro antibacterial activity of the peptide PsVP-10 against antimicrobial-resistant Enterococcus faecalis isolated from clinical samples
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 390-392; doi:10.1093/jac/dkh067 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Wen-Chien Ko, Hsin-Chun Lee, Shyh-Ren Chiang, Jing-Jou Yan, Jiunn-Jong Wu, Chin-Li Lu, and Yin-Ching Chuang

In vitro and in vivo activity of meropenem and sulbactam against a multidrug-resistant Acinetobacter baumannii strain
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 393-395; doi:10.1093/jac/dkh080 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Anne A. Delsol, Martin J. Woodward, and John M. Roe

Effect of a 5 day enrofloxacin treatment on Salmonella enterica serotype Typhimurium DT104 in the pig
JAC Advance Access published on January 7, 2004
J. Antimicrob. Chemother. 2004 53: 396-398; doi:10.1093/jac/dkh038 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Itzhak Brook and Alan E. Gober

Antimicrobial resistance in the nasopharyngeal flora of children with acute maxillary sinusitis and maxillary sinusitis recurring after amoxicillin therapy
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 399-402; doi:10.1093/jac/dkh061 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

Geoffrey A. Dugue

Comment on: Effect of antiretroviral protease inhibitors alone, and in combination with paromomycin, on the excystation, invasion and in vitro development of Cryptosporidium parvum
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 403; doi:10.1093/jac/dkh049 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Franz Petry, Vera Hommer, and Jutta Eichholz

Reply
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 403; doi:10.1093/jac/dkh064 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Michael H. Cynamon, Enriques Alvirez-Freites, and Anthony E. T. Yeo

BB-3497, a peptide deformylase inhibitor, is active against Mycobacterium tuberculosis
JAC Advance Access published on December 19, 2003
J. Antimicrob. Chemother. 2004 53: 403-405; doi:10.1093/jac/dkh054 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Helena Bujdáková, Miriam Filipová, Anna Lísková, and Hana Drahovská

Molecular characterization of hospital vancomycin-resistant Enterococcus faecalis isolated in Slovakia
JAC Advance Access published on December 19, 2003
J. Antimicrob. Chemother. 2004 53: 405-406; doi:10.1093/jac/dkh051 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

M. Wootton, M. B. Avison, P. M. Bennett, R. A. Howe, A. P. MacGowan, and T. R. Walsh

Genetic analysis of 17 genes in Staphylococcus aureus with reduced susceptibility to vancomycin (VISA) and heteroVISA
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 406-407; doi:10.1093/jac/dkh086 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

C. M. Yates, D. J. Brown, G. F. S. Edwards, and S. G. B. Amyes

Detection of TEM-52 in Salmonella enterica serovar Enteritidis isolated in Scotland
JAC Advance Access published on December 19, 2003
J. Antimicrob. Chemother. 2004 53: 407-408; doi:10.1093/jac/dkh045 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

B. Alcalá, C. Salcedo, L. de la Fuente, L. Arreaza, M. J. Uría, R. Abad, R. Enríquez, J. A. Vázquez, M. Motgé, and J. de Batlle

Neisseria meningitidis showing decreased susceptibility to ciprofloxacin: first report in Spain
JAC Advance Access published on January 16, 2004
J. Antimicrob. Chemother. 2004 53: 409; doi:10.1093/jac/dkh075 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Book reviews:

Clinical Bacteriology
J. Antimicrob. Chemother. 2004 53: 410; doi:10.1093/jac/dkh091 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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