Journal of Antimicrobial Chemotherapy

Appreciation:

Frank Odds

Professor Emlyn Glyn Vaughan Evans
J. Antimicrob. Chemother. 2003 52: 537; doi:10.1093/jac/dkg448 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Leading articles:

Pramod M. Shah and Robin D. Isaacs

Ertapenem, the first of a new group of carbapenems
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 538-542; doi:10.1093/jac/dkg404 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Jim Zhen Wu, Chin-chung Lin, and Zhi Hong

Ribavirin, viramidine and adenosine-deaminase-catalysed drug activation: implication for nucleoside prodrug design
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 543-546; doi:10.1093/jac/dkg405 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Nancy A. Jewell, Renxiang Chen, Raquel Raices, and Louis M. Mansky

Nucleoside reverse transcriptase inhibitors and HIV mutagenesis
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 547-550; doi:10.1093/jac/dkg387 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

A. Fraternale, A. Casabianca, L. Rossi, L. Chiarantini, G. F. Schiavano, A. T. Palamara, E. Garaci, and M. Magnani

Erythrocytes as carriers of reduced glutathione (GSH) in the treatment of retroviral infections
JAC Advance Access published on September 12, 2003
J. Antimicrob. Chemother. 2003 52: 551-554; doi:10.1093/jac/dkg428 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Reviews:

J. J. Oosterheert, M. J. M. Bonten, E. Hak, M. M. E. Schneider, and I. M. Hoepelman

How good is the evidence for the recommended empirical antimicrobial treatment of patients hospitalized because of community-acquired pneumonia? A systematic review
JAC Advance Access published on September 12, 2003
J. Antimicrob. Chemother. 2003 52: 555-563; doi:10.1093/jac/dkg413 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Leonard Leibovici, Karla Soares-Weiser, Mical Paul, Elad Goldberg, Andrew Herxheimer, and Paul Garner

Considering resistance in systematic reviews of antibiotic treatment
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 564-571; doi:10.1093/jac/dkg409 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Yang Li, Takehiko Mima, Yukiko Komori, Yuji Morita, Teruo Kuroda, Tohru Mizushima, and Tomofusa Tsuchiya

A new member of the tripartite multidrug efflux pumps, MexVW–OprM, in Pseudomonas aeruginosa
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 572-575; doi:10.1093/jac/dkg390 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Hidetada Hirakawa, Kunihiko Nishino, Junko Yamada, Takahiro Hirata, and Akihito Yamaguchi

ß-Lactam resistance modulated by the overexpression of response regulators of two-component signal transduction systems in Escherichia coli
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 576-582; doi:10.1093/jac/dkg406 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Mark A. Toleman, Doug Biedenbach, David Bennett, Ronald N. Jones, and Timothy R. Walsh

Genetic characterization of a novel metallo-ß-lactamase gene, bla_IMP-13, harboured by a novel Tn5051-type transposon disseminating carbapenemase genes in Europe: report from the SENTRY worldwide antimicrobial surveillance programme
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 583-590; doi:10.1093/jac/dkg410 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Yves De Gheldre, Véronique Avesani, Catherine Berhin, Michel Delmée, and Youri Glupczynski

Evaluation of Oxoid combination discs for detection of extended-spectrum ß-lactamases
JAC Advance Access published on September 12, 2003
J. Antimicrob. Chemother. 2003 52: 591-597; doi:10.1093/jac/dkg415 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Sabine Favre-Bonté, Thilo Köhler, and Christian Van Delden

Biofilm formation by Pseudomonas aeruginosa: role of the C₄-HSL cell-to-cell signal and inhibition by azithromycin
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 598-604; doi:10.1093/jac/dkg397 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Vito Ricci and Laura Piddock

Accumulation of garenoxacin by Bacteroides fragilis compared with that of five fluoroquinolones
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 605-609; doi:10.1093/jac/dkg418 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Hugues Chanteux, Marie-Paule Mingeot-Leclercq, Etienne Sonveaux, Françoise Van Bambeke, and Paul M. Tulkens

Intracellular accumulation and activity of ampicillin used as free drug and as its phthalimidomethyl or pivaloyloxymethyl ester (pivampicillin) against Listeria monocytogenes in J774 macrophages
JAC Advance Access published on September 12, 2003
J. Antimicrob. Chemother. 2003 52: 610-615; doi:10.1093/jac/dkg431 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Stephen H. Zinner, Irene Yu. Lubenko, Deborah Gilbert, Kelly Simmons, Xilin Zhao, Karl Drlica, and Alexander A. Firsov

Emergence of resistant Streptococcus pneumoniae in an in vitro dynamic model that simulates moxifloxacin concentrations inside and outside the mutant selection window: related changes in susceptibility, resistance frequency and bacterial killing
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 616-622; doi:10.1093/jac/dkg401 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Adam J. Houlihan and James B. Russell

The susceptibility of ionophore-resistant Clostridium aminophilum F to other antibiotics
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 623-628; doi:10.1093/jac/dkg398 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Stéphane Corvec, Nathalie Caroff, Eric Espaze, Cécile Giraudeau, Henri Drugeon, and Alain Reynaud

AmpC cephalosporinase hyperproduction in Acinetobacter baumannii clinical strains
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 629-635; doi:10.1093/jac/dkg407 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Helena Seppälä, Marjo Haanperä, Mohammad Al-Juhaish, Helinä Järvinen, Jari Jalava, and Pentti Huovinen

Antimicrobial susceptibility patterns and macrolide resistance genes of viridans group streptococci from normal flora
JAC Advance Access published on September 12, 2003
J. Antimicrob. Chemother. 2003 52: 636-644; doi:10.1093/jac/dkg423 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ingegerd Gustafsson, Maria Sjölund, Erik Torell, Marie Johannesson, Lars Engstrand, Otto Cars, and Dan I. Andersson

Bacteria with increased mutation frequency and antibiotic resistance are enriched in the commensal flora of patients with high antibiotic usage
JAC Advance Access published on September 12, 2003
J. Antimicrob. Chemother. 2003 52: 645-650; doi:10.1093/jac/dkg427 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

I. Lutsar, I. R. Friedland, H. S. Jafri, L. Wubbel, A. Ahmed, M. Trujillo, C. C. McCoig, and G. H. McCracken, Jr

Factors influencing the anti-inflammatory effect of dexamethasone therapy in experimental pneumococcal meningitis
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 651-655; doi:10.1093/jac/dkg417 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

John R. Graybill, Rosie Bocanegra, Gloria M. Gonzalez, and Laura K. Najvar

Combination antifungal therapy of murine aspergillosis: liposomal amphotericin B and micafungin
JAC Advance Access published on September 12, 2003
J. Antimicrob. Chemother. 2003 52: 656-662; doi:10.1093/jac/dkg425 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Nehama Linder, Gil Klinger, Itamar Shalit, Itzhak Levy, Shai Ashkenazi, Gali Haski, Orli Levit, and Lea Sirota

Treatment of candidaemia in premature infants: comparison of three amphotericin B preparations
JAC Advance Access published on September 12, 2003
J. Antimicrob. Chemother. 2003 52: 663-667; doi:10.1093/jac/dkg419 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Sheryl A. Zelenitsky, Godfrey K. M. Harding, Siyao Sun, Kiran Ubhi, and Robert E. Ariano

Treatment and outcome of Pseudomonas aeruginosa bacteraemia: an antibiotic pharmacodynamic analysis
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 668-674; doi:10.1093/jac/dkg403 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Antimicrobial practice:

Marijke M. Kuyvenhoven, Frank A. M. van Balen, and Theo J. M. Verheij

Outpatient antibiotic prescriptions from 1992 to 2001 in The Netherlands
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 675-678; doi:10.1093/jac/dkg412 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Anna Maria Tortorano, Anna Lisa Rigoni, Emanuela Biraghi, Anna Prigitano, Maria Anna Viviani, and the FIMUA–ECMM candidaemia study group

The European Confederation of Medical Mycology ECMM) survey of candidaemia in Italy: antifungal susceptibility patterns of 261 non-albicans Candida isolates from blood
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 679-682; doi:10.1093/jac/dkg393 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

K. Datta, N. Jain, S. Sethi, A. Rattan, A. Casadevall, and U. Banerjee

Fluconazole and itraconazole susceptibility of clinical isolates of Cryptococcus neoformans at a tertiary care centre in India: a need for care
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 683-686; doi:10.1093/jac/dkg399 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Richard P. Spence and Kevin J. Towner

Frequencies and mechanisms of resistance to moxifloxacin in nosocomial isolates of Acinetobacter baumannii
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 687-690; doi:10.1093/jac/dkg424 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Névine El Solh, Marilyne Davi, Anne Morvan, Hélène Aubry Damon, Nicole Marty, and the other members of the GISA group, RAISIN subgroup

Characteristics of French methicillin-resistant Staphylococcus aureus isolates with decreased susceptibility or resistance to glycopeptides
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 691-694; doi:10.1093/jac/dkg400 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Isis Tamargo, Kiomy Fuentes, Alina Llop, Jesús Oteo, and José Campos

High levels of multiple antibiotic resistance among 938 Haemophilus influenzae type b meningitis isolates from Cuba (1990–2002)
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 695-698; doi:10.1093/jac/dkg395 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ana C. Gales, Liana C. Menezes, Suzane Silbert, and Hélio S. Sader

Dissemination in distinct Brazilian regions of an epidemic carbapenem-resistant Pseudomonas aeruginosa producing SPM metallo-ß-lactamase
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 699-702; doi:10.1093/jac/dkg416 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

J. M. Rodríguez-Martínez, A. Pascual, I. García, and L. Martínez-Martínez

Detection of the plasmid-mediated quinolone resistance determinant qnr among clinical isolates of Klebsiella pneumoniae producing AmpC-type ß-lactamase
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 703-706; doi:10.1093/jac/dkg388 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Sue Solway, Lindsey Vincent, Natasha Tian, Neil Woodford, and Richard Bendall

Isolation of streptogramin-resistant Enterococcus faecium from human and non-human sources in a rural community
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 707-710; doi:10.1093/jac/dkg389 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Neil Woodford, Rosy Reynolds, Jane Turton, Fiona Scott, Alistair Sinclair, Andrea Williams, and David Livermore

Two widely disseminated strains of Enterococcus faecalis highly resistant to gentamicin and ciprofloxacin from bacteraemias in the UK and Ireland
JAC Advance Access published on August 13, 2003
J. Antimicrob. Chemother. 2003 52: 711-714; doi:10.1093/jac/dkg408 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Frank M. Aarestrup, Monton Lertworapreecha, Mary C. Evans, Aroon Bangtrakulnonth, Thongchai Chalermchaikit, Rene Sjøgren Hendriksen, and Henrik Caspar Wegener

Antimicrobial susceptibility and occurrence of resistance genes among Salmonella enterica serovar Weltevreden from different countries
JAC Advance Access published on September 12, 2003
J. Antimicrob. Chemother. 2003 52: 715-718; doi:10.1093/jac/dkg426 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Michiel van Boven, Kees T. Veldman, Mart C. M. de Jong, and Dik J. Mevius

Rapid selection of quinolone resistance in Campylobacter jejuni but not in Escherichia coli in individually housed broilers
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 719-723; doi:10.1093/jac/dkg402 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Andrea Giacometti, Roberto Ghiselli, Oscar Cirioni, Federico Mocchegiani, Fiorenza Orlando, Maria Simona Del Prete, Giuseppina D’Amato, Carmela Silvestri, Vittorio Saba, and Giorgio Scalise

Prophylactic efficacy of linezolid alone or combined with levofloxacin and vancomycin in a rat subcutaneous pouch model of graft infection caused by Staphylococcus epidermidis with intermediate resistance to glycopeptides
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 724-726; doi:10.1093/jac/dkg396 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

P. L. A. Fraaij, A. S. Bergshoeff, A. M. C. van Rossum, N. G. Hartwig, D. M. Burger, and R. de Groot

Changes in indinavir exposure over time: a case study in six HIV-1-infected children
JAC Advance Access published on August 13, 2003
J. Antimicrob. Chemother. 2003 52: 727-730; doi:10.1093/jac/dkg391 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

Xilin Zhao

Clarification of MPC and the mutant selection window concept
JAC Advance Access published on September 12, 2003
J. Antimicrob. Chemother. 2003 52: 731; doi:10.1093/jac/dkg376 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

David M. Livermore

Overstretching the mutant prevention concentration
JAC Advance Access published on September 12, 2003
J. Antimicrob. Chemother. 2003 52: 732; doi:10.1093/jac/dkg377 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Heather J. Smith, Daryl J. Hoban, and George G. Zhanel

Reply
JAC Advance Access published on September 12, 2003
J. Antimicrob. Chemother. 2003 52: 732-733; doi:10.1093/jac/dkg421 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

J. M. Andrews, J. P. Ashby, G. Jevons, and R. Wise

In vitro susceptibility of ertapenem by BSAC standardized methodology
JAC Advance Access published on September 12, 2003
J. Antimicrob. Chemother. 2003 52: 733-734; doi:10.1093/jac/dkg430 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Eugenne Elliott, Deon Oosthuizen, Maggie M Johnson, and Laura J. V. Piddock

Fluoroquinolone resistance in Haemophilus influenzae
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 734-735; doi:10.1093/jac/dkg420 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Jose E. Martin-Herrero, Cesar Garcia-Rey, Rafael Dal-Ré, and Lorenzo Aguilar

Clinical and bacteriological implications of macrolide resistance in group A streptococcal pharyngitis
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 735-736; doi:10.1093/jac/dkg414 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Satoru Kaieda, Naohiro Okitsu, Hisakazu Yano, Yoshio Hosaka, Ryuichi Nakano, Ryouichi Okamoto, Haruo Takahashi, and Matsuhisa Inoue

Induction of telithromycin resistance in Streptococcus pneumoniae
JAC Advance Access published on September 1, 2003
J. Antimicrob. Chemother. 2003 52: 736-737; doi:10.1093/jac/dkg411 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

A. J. Smith, D. Morrison, Douglas Robertson, Michael K. Tang, and Z. Al-Doori

Efficacy of oral hygiene products against MRSA and MSSA isolates
JAC Advance Access published on August 13, 2003
J. Antimicrob. Chemother. 2003 52: 738-739; doi:10.1093/jac/dkg394 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Book reviews:

Antimicrobial Therapy and Vaccines, Second Edition, Volume 1: Microbes
J. Antimicrob. Chemother. 2003 52: 740; doi:10.1093/jac/dkg432 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Antibiotic and Chemotherapy: Anti-infective Agents and Their Use in Therapy, Eighth Edition
J. Antimicrob. Chemother. 2003 52: 740-741; doi:10.1093/jac/dkg433 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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