Journal of Antimicrobial Chemotherapy

Leading articles:

Gunnar Kahlmeter, Derek F. J. Brown, Fred W. Goldstein, Alasdair P. MacGowan, Johan W. Mouton, Anders Österlund, Arne Rodloff, Martin Steinbakk, Pavla Urbaskova, and Alkiviadis Vatopoulos

European harmonization of MIC breakpoints for antimicrobial susceptibility testing of bacteria
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 145-148; doi:10.1093/jac/dkg312 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Shiou-Hwei Yeh, Ding-Shinn Chen, and Pei-Jer Chen

A prospect for pharmacogenomics in the interferon therapy of chronic viral hepatitis
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 149-151; doi:10.1093/jac/dkg326 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Michelle Swanson-Mungerson, Masato Ikeda, Lori Lev, Richard Longnecker, and Toni Portis

Identification of latent membrane protein 2A (LMP2A) specific targets for treatment and eradication of Epstein–Barr virus (EBV)-associated diseases
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 152-154; doi:10.1093/jac/dkg306 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Rafael de la Rosa and Manuel Leal

Thymic involvement in recovery of immunity among HIV-infected adults on highly active antiretroviral therapy
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 155-158; doi:10.1093/jac/dkg311 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Reviews:

Mark Casewell, Christian Friis, Enric Marco, Paul McMullin, and Ian Phillips

The European ban on growth-promoting antibiotics and emerging consequences for human and animal health
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 159-161; doi:10.1093/jac/dkg313 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Anita Hällgren, Baharak Saeedi, Maud Nilsson, Hans-Jürg Monstein, Barbro Isaksson, Håkan Hanberger, and Lennart E. Nilsson

Genetic relatedness among Enterococcus faecalis with transposon-mediated high-level gentamicin resistance in Swedish intensive care units
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 162-167; doi:10.1093/jac/dkg315 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Todd A. Davies, Raul Goldschmidt, Sharon Pfleger, Mike Loeloff, Karen Bush, Daniel F. Sahm, and Alan Evangelista

Cross-resistance, relatedness and allele analysis of fluoroquinolone-resistant US clinical isolates of Streptococcus pneumoniae (1998–2000)
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 168-175; doi:10.1093/jac/dkg309 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jing Chen, Teruo Kuroda, Md Nazmul Huda, Tohru Mizushima, and Tomofusa Tsuchiya

An RND-type multidrug efflux pump SdeXY from Serratia marcescens
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 176-179; doi:10.1093/jac/dkg308 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Mickaël Riou, Fabrice Guégnard, Yves Le Vern, and Dominique Kerboeuf

Modulation of the multidrug resistance (MDR) system in the nematode Haemonchus contortus by changing cholesterol content: effects on resistance to anthelmintics
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 180-187; doi:10.1093/jac/dkg332 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

David C. Warhurst, Jonathan C. P. Steele, Ipemida S. Adagu, John C. Craig, and Christopher Cullander

Hydroxychloroquine is much less active than chloroquine against chloroquine-resistant Plasmodium falciparum, in agreement with its physicochemical properties
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 188-193; doi:10.1093/jac/dkg319 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

L. C. Chiang, W. Chiang, M. C. Liu, and C. C. Lin

In vitro antiviral activities of Caesalpinia pulcherrima and its related flavonoids
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 194-198; doi:10.1093/jac/dkg291 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

K. Sato, H. Tomioka, C. Sano, T. Shimizu, K. Sano, K. Ogasawara, S. Cai, and T. Kamei

Comparative antimicrobial activities of gatifloxacin, sitafloxacin and levofloxacin against Mycobacterium tuberculosis replicating within Mono Mac 6 human macrophage and A-549 type II alveolar cell lines
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 199-203; doi:10.1093/jac/dkg343 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

R. Skov, R. Smyth, M. Clausen, A. R. Larsen, N. Frimodt-Møller, B. Olsson-Liljequist, and G. Kahlmeter

Evaluation of a cefoxitin 30 µg disc on Iso-Sensitest agar for detection of methicillin-resistant Staphylococcus aureus
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 204-207; doi:10.1093/jac/dkg325 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Yoav Golan, Laura A. McDermott, Nilda V. Jacobus, Ellie J. C. Goldstein, Sydney Finegold, Lizzie J. Harrell, David W. Hecht, Stephen G. Jenkins, C. Pierson, Richard Venezia, Jack Rihs, Paul Iannini, Sherwood L. Gorbach, and David R. Snydman

Emergence of fluoroquinolone resistance among Bacteroides species
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 208-213; doi:10.1093/jac/dkg320 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Maria de Fátima Silva Lopes, Tânia Ribeiro, Maria Paula Martins, Rogério Tenreiro, and Maria Teresa Barreto Crespo

Gentamicin resistance in dairy and clinical enterococcal isolates and in reference strains
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 214-219; doi:10.1093/jac/dkg304 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. N. Oza, J. P. McKenna, S. W. J. McDowell, F. D. Menzies, and S. D. Neill

Antimicrobial susceptibility of Campylobacter spp. isolated from broiler chickens in Northern Ireland
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 220-223; doi:10.1093/jac/dkg333 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

J. S. Brazier, V. Hall, T. E. Morris, M. Gal, and B. I. Duerden

Antibiotic susceptibilities of Gram-positive anaerobic cocci: results of a sentinel study in England and Wales
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 224-228; doi:10.1093/jac/dkg316 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Michael R. Jacobs, David Felmingham, Peter C. Appelbaum, Reuben N. Grüneberg, and the Alexander Project Group

The Alexander Project 1998–2000: susceptibility of pathogens isolated from community-acquired respiratory tract infection to commonly used antimicrobial agents
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 229-246; doi:10.1093/jac/dkg321 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

J. F. Marier, J. L. Brazier, J. Lavigne, and M. P. Ducharme

Liposomal tobramycin against pulmonary infections of Pseudomonas aeruginosa: a pharmacokinetic and efficacy study following single and multiple intratracheal administrations in rats
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 247-252; doi:10.1093/jac/dkg317 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Christina Greko, Maria Finn, Anders Franklin, and Björn Bengtsson

Pharmacokinetic/pharmacodynamic relationship of danofloxacin against Mannheimia haemolytica in a tissue-cage model in calves
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 253-257; doi:10.1093/jac/dkg339 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ingegerd Gustafsson, Otto Cars, and Dan I. Andersson

Fitness of antibiotic resistant Staphylococcus epidermidis assessed by competition on the skin of human volunteers
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 258-263; doi:10.1093/jac/dkg331 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Pasquale Pagliano, Marco Rossi, Carolina Rescigno, Sergio Altieri, Maria Grazia Coppola, Marina Gramiccia, Aldo Scalone, Luigi Gradoni, and Francesco Faella

Mediterranean visceral leishmaniasis in HIV-negative adults: a retrospective analysis of 64 consecutive cases (1995–2001)
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 264-268; doi:10.1093/jac/dkg340 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Pierre-Marie Roger, Jacques Durant, Michel Ticchioni, Philippe Halfon, Jean-Philippe Breittmayer, Christelle Brignone, Sylvie Chaillou, Brigitte Dunais, Pierre Dellamonica, Alain Bernard, and for the Groupe d’Etudes Niçois Polyvalent en Infectiologie (GENPI)

Apoptosis and proliferation kinetics of T cells in patients having experienced antiretroviral treatment interruptions
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 269-275; doi:10.1093/jac/dkg295 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Chiara Atzori, Mario Clerici, Daria Trabattoni, Giovanna Fantoni, Antonella Valerio, Elisa Tronconi, and Antonietta Cargnel

Assessment of immune reconstitution to Pneumocystis carinii in HIV-1 patients under different highly active antiretroviral therapy regimens
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 276-281; doi:10.1093/jac/dkg314 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Antimicrobial practice:

D. Resi, M. Milandri, M. L. Moro, and the Emilia Romagna Study Group on the Use of Antibiotics in Children

Antibiotic prescriptions in children
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 282-286; doi:10.1093/jac/dkg302 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Porntip Chavalitshewinkoon-Petmitr, Muhaimin Ramdja, Somsri Kajorndechakiat, Raymond K. Ralph, William A. Denny, and Prapon Wilairat

In vitro susceptibility of Trichomonas vaginalis to AT-specific minor groove binding drugs
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 287-289; doi:10.1093/jac/dkg322 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Burkhard Klenke, Michael P. Barrett, Reto Brun, and Ian H. Gilbert

Antiplasmodial activity of a series of 1,3,5-triazine-substituted polyamines
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 290-293; doi:10.1093/jac/dkg307 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

John Frean, Keith P. Klugman, Lorraine Arntzen, and Stanley Bukofzer

Susceptibility of Yersinia pestis to novel and conventional antimicrobial agents
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 294-296; doi:10.1093/jac/dkg363 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

John Frean, Keith P. Klugman, Lorraine Arntzen, and Stanley Bukofzer

Susceptibility of Bacillus anthracis to eleven antimicrobial agents including novel fluoroquinolones and a ketolide
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 297-299; doi:10.1093/jac/dkg364 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Marilyn Hidalgo, Elizabeth Castañeda, and César A. Arias

Tolerance to vancomycin in a multiresistant, Colombian isolate of Streptococcus pneumoniae
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 300-302; doi:10.1093/jac/dkg336 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Maria Scrascia, Maria Forcillo, Francesco Maimone, and Carlo Pazzani

Susceptibility to rifaximin of Vibrio cholerae strains from different geographical areas
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 303-305; doi:10.1093/jac/dkg318 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Michael H. Cynamon, Shannon A. Elliott, Michelle S. DeStefano, and Anthony E. T. Yeo

Activity of clarithromycin alone and in combination in a murine model of Mycobacterium kansasii infection
JAC Advance Access published on July 1, 2003
J. Antimicrob. Chemother. 2003 52: 306-307; doi:10.1093/jac/dkg323 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Åsa Sullivan, Lisbeth Barkholt, and Carl Erik Nord

Lactobacillus acidophilus, Bifidobacterium lactis and Lactobacillus F19 prevent antibiotic-associated ecological disturbances of Bacteroides fragilis in the intestine
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 308-311; doi:10.1093/jac/dkg346 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

L. Mark Fisher, Katherine A. Gould, Xiao-Su Pan, Sandhiya Patel, and Victoria J. Heaton

Analysis of dual active fluoroquinolones in Streptococcus pneumoniae
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 312-313; doi:10.1093/jac/dkg329 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Heather J. Smith, Kimberly A. Nichol, Daryl J. Hoban, and George G. Zhanel

Reply
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 313-314; doi:10.1093/jac/dkg330 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

R. J. Lewis, C. Torkornoo, C. N. H. Marques, S. M. Nelson, and V. C. Salisbury

Inhibition of bacteria on agar surfaces by vapour phase triclosan
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 314-315; doi:10.1093/jac/dkg327 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

M.-F. Lartigue, L. Poirel, C. Héritier, V. Tolün, and P. Nordmann

First description of CTX-M-15-producing Klebsiella pneumoniae in Turkey
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 315-316; doi:10.1093/jac/dkg335 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Corrigenda:

K. Kümmerer

Significance of antibiotics in the environment
JAC Advance Access published on July 15, 2003
J. Antimicrob. Chemother. 2003 52: 317; doi:10.1093/jac/dkg386 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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