Journal of Antimicrobial Chemotherapy

Leading articles:

Heather J. Smith, Kimberly A. Nichol, Daryl J. Hoban, and George G. Zhanel

Stretching the mutant prevention concentration (MPC) beyond its limits
JAC Advance Access published on April 25, 2003
J. Antimicrob. Chemother. 2003 51: 1323-1325; doi:10.1093/jac/dkg255 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Beatrice Macchi, Emanuela Balestrieri, and Antonio Mastino

Effects of nucleoside-based antiretroviral chemotherapy on human T cell leukaemia/lymphotropic virus type 1 (HTLV-1) infection in vitro
JAC Advance Access published on April 25, 2003
J. Antimicrob. Chemother. 2003 51: 1327-1330; doi:10.1093/jac/dkg240 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Reviews:

Itzhak Brook

Effects of antimicrobial therapy on the microbial flora of the adenoids
JAC Advance Access published on May 13, 2003
J. Antimicrob. Chemother. 2003 51: 1331-1337; doi:10.1093/jac/dkg260 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Claudia Thomas, Mark Stevenson, and Thomas V. Riley

Antibiotics and hospital-acquired Clostridium difficile-associated diarrhoea: a systematic review
JAC Advance Access published on May 13, 2003
J. Antimicrob. Chemother. 2003 51: 1339-1350; doi:10.1093/jac/dkg254 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Pannika Niumsup, Alan M. Simm, Kurshid Nurmahomed, Timothy R. Walsh, Peter M. Bennett, and Matthew B. Avison

Genetic linkage of the penicillinase gene, amp, and blrAB, encoding the regulator of ß-lactamase expression in Aeromonas spp.
JAC Advance Access published on May 13, 2003
J. Antimicrob. Chemother. 2003 51: 1351-1358; doi:10.1093/jac/dkg247 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

C. Faber, H. P. Stallmann, D. M. Lyaruu, J. M. A. de Blieck, Th. J. M. Bervoets, A. van Nieuw Amerongen, and P. I. J. M. Wuisman

Release of antimicrobial peptide Dhvar-5 from polymethylmethacrylate beads
JAC Advance Access published on April 25, 2003
J. Antimicrob. Chemother. 2003 51: 1359-1364; doi:10.1093/jac/dkg258 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Aaron Ingham, Mark Ford, Robert J. Moore, and Mark Tizard

The bacteriocin piscicolin 126 retains antilisterial activity in vivo
JAC Advance Access published on April 25, 2003
J. Antimicrob. Chemother. 2003 51: 1365-1371; doi:10.1093/jac/dkg229 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

John R. Graybill, Laura K. Najvar, Gloria M. Gonzalez, Steve Hernandez, and Rosie Bocanegra

Improving the mouse model for studying the efficacy of voriconazole
JAC Advance Access published on May 13, 2003
J. Antimicrob. Chemother. 2003 51: 1373-1376; doi:10.1093/jac/dkg261 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

George M. Bahr, Xavier De La Tribonnière, Edith Darcissac, Faïza Ajana, Laurence Bocket, Daouda Sissoko, Yazdan Yazdanpanah, Joëlle Dewulf, Corinne Amiel, and Yves Mouton

Clinical and immunological effects of a 6 week immunotherapy cycle with murabutide in HIV-1 patients with unsuccessful long-term antiretroviral treatment
JAC Advance Access published on April 25, 2003
J. Antimicrob. Chemother. 2003 51: 1377-1388; doi:10.1093/jac/dkg244 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Antimicrobial practice:

M. E. E. van Kasteren, B. J. Kullberg, A. S. de Boer, J. Mintjes-de Groot, and I. C. Gyssens

Adherence to local hospital guidelines for surgical antimicrobial prophylaxis: a multicentre audit in Dutch hospitals
JAC Advance Access published on May 13, 2003
J. Antimicrob. Chemother. 2003 51: 1389-1396; doi:10.1093/jac/dkg264 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Carla C. Lange, Christiane Werckenthin, and Stefan Schwarz

Molecular analysis of the plasmid-borne aacA/aphD resistance gene region of coagulase-negative staphylococci from chickens
JAC Advance Access published on April 25, 2003
J. Antimicrob. Chemother. 2003 51: 1397-1401; doi:10.1093/jac/dkg257 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Deborah J. Griggs, Herida Marona, and Laura J. V. Piddock

Selection of moxifloxacin-resistant Staphylococcus aureus compared with five other fluoroquinolones
JAC Advance Access published on April 25, 2003
J. Antimicrob. Chemother. 2003 51: 1403-1407; doi:10.1093/jac/dkg241 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

S. Pournaras, M. Maniati, E. Petinaki, L. S. Tzouvelekis, A. Tsakris, N. J. Legakis, and A. N. Maniatis

Hospital outbreak of multiple clones of Pseudomonas aeruginosa carrying the unrelated metallo-ß-lactamase gene variants bla_VIM-2 and bla_VIM-4
JAC Advance Access published on April 25, 2003
J. Antimicrob. Chemother. 2003 51: 1409-1414; doi:10.1093/jac/dkg239 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Reanne Hughes, John Dart, and Simon Kilvington

Activity of the amidoamine myristamidopropyl dimethylamine against keratitis pathogens
JAC Advance Access published on April 25, 2003
J. Antimicrob. Chemother. 2003 51: 1415-1418; doi:10.1093/jac/dkg259 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

N. Berthet, O. Faure, A. Bakri, P. Ambroise-Thomas, R. Grillot, and J.-F. Brugère

In vitro susceptibility of Aspergillus spp. clinical isolates to albendazole
JAC Advance Access published on April 25, 2003
J. Antimicrob. Chemother. 2003 51: 1419-1422; doi:10.1093/jac/dkg245 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Elias K. Manavathu, George J. Alangaden, and Pranatharthi H. Chandrasekar

Differential activity of triazoles in two-drug combinations with the echinocandin caspofungin against Aspergillus fumigatus
JAC Advance Access published on April 25, 2003
J. Antimicrob. Chemother. 2003 51: 1423-1425; doi:10.1093/jac/dkg242 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Mohammad A. Hossain, Guadalupe H. Reyes, Lisa A. Long, Pranab K. Mukherjee, and Mahmoud A. Ghannoum

Efficacy of caspofungin combined with amphotericin B against azole-resistant Candida albicans
JAC Advance Access published on April 25, 2003
J. Antimicrob. Chemother. 2003 51: 1427-1429; doi:10.1093/jac/dkg230 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

David Honeybourne, Caroline Tobin, Gail Jevons, Jenny Andrews, and Richard Wise

Intrapulmonary penetration of linezolid
JAC Advance Access published on May 13, 2003
J. Antimicrob. Chemother. 2003 51: 1431-1434; doi:10.1093/jac/dkg262 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

S. Fraud, E. L. Rees, E. Mahenthiralingam, A. D. Russell, and J.-Y. Maillard

Aromatic alcohols and their effect on Gram-negative bacteria, cocci and mycobacteria
JAC Advance Access published on April 25, 2003
J. Antimicrob. Chemother. 2003 51: 1435-1436; doi:10.1093/jac/dkg246 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

A. A. F. Elsaghier, J. S. Brazier, and E. A. James

Bacteraemia due to Bacteroides fragilis with reduced susceptibility to metronidazole
JAC Advance Access published on May 13, 2003
J. Antimicrob. Chemother. 2003 51: 1436-1437; doi:10.1093/jac/dkg265 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Kim L. Credito, Michael R. Jacobs, and Peter C. Appelbaum

In vitro activity of faropenem compared with eight agents against fourteen Gram-positive and Gram-negative bacteria by time–kill
JAC Advance Access published on May 13, 2003
J. Antimicrob. Chemother. 2003 51: 1437-1439; doi:10.1093/jac/dkg263 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Corrigenda:

Dilip Nathwani

From evidence-based guideline methodology to quality of care standards
J. Antimicrob. Chemother. 2003 51: 1441; doi:10.1093/jac/dkg324 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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