Journal of Antimicrobial Chemotherapy

Leading articles:

Alan P. Johnson and Neil Woodford

Glycopeptide-resistant Staphylococcus aureus
JAC Advance Access published on October 22, 2002
J. Antimicrob. Chemother. 2002 50: 621-623; doi:10.1093/jac/dkf244 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Å. Sullivan and C. E. Nord

Probiotics in human infections
JAC Advance Access published on October 8, 2002
J. Antimicrob. Chemother. 2002 50: 625-627; doi:10.1093/jac/dkf194 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Ana O. de Souza, Fernando P. Hemerly, Adriana C. Busollo, Patrícia S. Melo, Gérzia M. C. Machado, Cristiana C. Miranda, Ricardo M. Santa-Rita, Marcela Haun, Leonor L. Leon, Daisy N. Sato, Solange L. de Castro, and Nelson Durán

3-[4'-Bromo-(1,1'-biphenyl)-4-yl]-N,N-dimethyl-3-(2-thienyl)-2-propen-1-amine: synthesis, cytotoxicity, and leishmanicidal, trypanocidal and antimycobacterial activities
JAC Advance Access published on October 8, 2002
J. Antimicrob. Chemother. 2002 50: 629-637; doi:10.1093/jac/dkf188 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Luigia Rossi, Sonja Serafini, Palmarisa Franchetti, Anna Casabianca, Chiara Orlandi, Giuditta Fiorella Schiavano, Andrea Carnevali, and Mauro Magnani

Inhibition of murine AIDS by a heterodinucleotide of azidothymidine and 9-(R)-2-(phosphonomethoxypropyl)adenine
JAC Advance Access published on October 8, 2002
J. Antimicrob. Chemother. 2002 50: 639-647; doi:10.1093/jac/dkf205 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Fatima Hannachi-M’Zali, Jane E. Ambler, Claire F. Taylor, and Peter M. Hawkey

Examination of single and multiple mutations involved in resistance to quinolones in Staphylococcus aureus by a combination of PCR and denaturing high-performance liquid chromatography (DHPLC)
JAC Advance Access published on October 8, 2002
J. Antimicrob. Chemother. 2002 50: 649-655; doi:10.1093/jac/dkf243 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Patricia Sánchez, Juan Francisco Linares, Beatriz Ruiz-Díez, Ester Campanario, Alfonso Navas, Fernando Baquero, and José L. Martínez

Fitness of in vitro selected Pseudomonas aeruginosa nalB and nfxB multidrug resistant mutants
JAC Advance Access published on October 8, 2002
J. Antimicrob. Chemother. 2002 50: 657-664; doi:10.1093/jac/dkf185 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Curtis G. Gemmell and Charles W. Ford

Virulence factor expression by Gram-positive cocci exposed to subinhibitory concentrations of linezolid
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 665-672; doi:10.1093/jac/dkf192 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Mark A. Toleman, Alan M. Simm, Tanya A. Murphy, Ana C. Gales, Doug J. Biedenbach, Ronald N. Jones, and Timothy R. Walsh

Molecular characterization of SPM-1, a novel metallo-ß-lactamase isolated in Latin America: report from the SENTRY antimicrobial surveillance programme
JAC Advance Access published on October 8, 2002
J. Antimicrob. Chemother. 2002 50: 673-679; doi:10.1093/jac/dkf210 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Dominique Decré, Charlotte Verdet, Laurent Raskine, Hervé Blanchard, Béatrice Burghoffer, Alain Philippon, Marie José Sanson-Le-Pors, Jean Claude Petit, and Guillaume Arlet

Characterization of CMY-type ß-lactamases in clinical strains of Proteus mirabilis and Klebsiella pneumoniae isolated in four hospitals in the Paris area
JAC Advance Access published on October 22, 2002
J. Antimicrob. Chemother. 2002 50: 681-688; doi:10.1093/jac/dkf193 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Fiona M. MacKenzie, Paul Greig, Donald Morrison, Giles Edwards, and Ian M. Gould

Identification and characterization of teicoplanin-intermediate Staphylococcus aureus blood culture isolates in NE Scotland
JAC Advance Access published on October 8, 2002
J. Antimicrob. Chemother. 2002 50: 689-697; doi:10.1093/jac/dkf191 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Dagmar Mainz, Klaus Borner, Peter Koeppe, Jochen Kotwas, and Hartmut Lode

Pharmacokinetics of lansoprazole, amoxicillin and clarithromycin after simultaneous and single administration
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 699-706; doi:10.1093/jac/dkf172 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Olaf Burkhardt, Klaus Borner, Nicolas von der Höh, Peter Köppe, Mathias Wilhelm Pletz, Carl Erik Nord, and Hartmut Lode

Single- and multiple-dose pharmacokinetics of linezolid and co-amoxiclav in healthy human volunteers
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 707-712; doi:10.1093/jac/dkf163 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

C. M. Tobin, J. M. Darville, A. H. Thomson, G. Sweeney, J. F. Wilson, A. P. MacGowan, and L. O. White

Vancomycin therapeutic drug monitoring: is there a consensus view? The results of a UK National External Quality Assessment Scheme (UK NEQAS) for Antibiotic Assays questionnaire
JAC Advance Access published on October 8, 2002
J. Antimicrob. Chemother. 2002 50: 713-718; doi:10.1093/jac/dkf212 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

A. Aberkane, M. Cuenca-Estrella, A. Gomez-Lopez, E. Petrikkou, E. Mellado, A. Monzón, J. L. Rodriguez-Tudela, and the Eurofung Network

Comparative evaluation of two different methods of inoculum preparation for antifungal susceptibility testing of filamentous fungi
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 719-722; doi:10.1093/jac/dkf187 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

P. L. Ho, Terence K. M. Cheung, W. C. Yam, and K. Y. Yuen

Characterization of a laboratory-generated variant of BPS ß-lactamase from Burkholderia pseudomallei that hydrolyses ceftazidime
JAC Advance Access published on October 22, 2002
J. Antimicrob. Chemother. 2002 50: 723-726; doi:10.1093/jac/dkf208 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Arvind M. Dhople and Kenji Namba

In vitro activity of sitafloxacin (DU-6859a) alone, or in combination with rifampicin, against Mycobacterium ulcerans
JAC Advance Access published on October 8, 2002
J. Antimicrob. Chemother. 2002 50: 727-729; doi:10.1093/jac/dkf218 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

W. Brumfitt, M. R. J. Salton, and J. M. T. Hamilton-Miller

Nisin, alone and combined with peptidoglycan-modulating antibiotics: activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 731-734; doi:10.1093/jac/dkf190 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Barbara A. Pelak, Diane M. Citron, Mary Motyl, Ellie J. C. Goldstein, Gail L. Woods, and Hedy Teppler

Comparative in vitro activities of ertapenem against bacterial pathogens from patients with acute pelvic infection
JAC Advance Access published on October 8, 2002
J. Antimicrob. Chemother. 2002 50: 735-741; doi:10.1093/jac/dkf203 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Cressida Auckland, Louise Teare, Fiona Cooke, Mary E. Kaufmann, Marina Warner, Graeme Jones, Kathy Bamford, Helen Ayles, and Alan P. Johnson

Linezolid-resistant enterococci: report of the first isolates in the United Kingdom
JAC Advance Access published on October 22, 2002
J. Antimicrob. Chemother. 2002 50: 743-746; doi:10.1093/jac/dkf246 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

B. Rana, I. Butcher, P. Grigoris, C. Murnaghan, R. A. Seaton, and C. M. Tobin

Linezolid penetration into osteo-articular tissues
JAC Advance Access published on October 22, 2002
J. Antimicrob. Chemother. 2002 50: 747-750; doi:10.1093/jac/dkf207 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Steffen Borrmann, Nicole Szlezák, Ronald K. Binder, Michel A. Missinou, Bertrand Lell, and Peter G. Kremsner

Evidence for the efficacy of artesunate in asymptomatic Plasmodium malariae infections
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 751-754; doi:10.1093/jac/dkf200 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

Olivier Denis, Juana Magdalena, Ariane Deplano, Claire Nonhoff, Erik Hendrickx, and Marc J. Struelens

Molecular epidemiology of resistance to macrolides–lincosamides–streptogramins in methicillin-resistant Staphylococcus aureus (MRSA) causing bloodstream infections in patients admitted to Belgian hospitals
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 755-757; doi:10.1093/jac/dkf197 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

J. M. Andrews, R. Wise, and on behalf of the BSAC Working Party on Sensitivity Testing

A survey of susceptibility testing of anaerobes in the United Kingdom
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 757; doi:10.1093/jac/dkf201 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Carmen Betriu, Iciar Rodríguez-Avial, Blas Ali Sánchez, María Gómez, and Juan J. Picazo

Comparative in vitro activities of tigecycline (GAR-936) and other antimicrobial agents against Stenotrophomonas maltophilia
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 758-759; doi:10.1093/jac/dkf196 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

M. Wootton, R. A. Howe, T. R. Walsh, P. M. Bennett, and A. P. MacGowan

In vitro activity of 21 antimicrobials against vancomycin-resistant Staphylococcus aureus (VRSA) and heteroVRSA (hVRSA)
JAC Advance Access published on October 22, 2002
J. Antimicrob. Chemother. 2002 50: 760-761; doi:10.1093/jac/dkf184 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

A. F. Cheng, T. S. Char, and J. M. Ling

Are multiply resistant enterococci a common phenomenon in Hong Kong?
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 761-763; doi:10.1093/jac/dkf195 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Nicola Abrescia, Maurizio D’Abbraccio, Mario Figoni, Annunziata Busto, Ettore Butrico, Mario De Marco, and Rosaria Viglietti

Fulminant hepatic failure after the start of an efavirenz-based HAART regimen in a treatment-naive female AIDS patient without hepatitis virus co-infection
JAC Advance Access published on October 8, 2002
J. Antimicrob. Chemother. 2002 50: 763-765; doi:10.1093/jac/dkf204 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

N. Bodasing, R. A. Seaton, G. S. Shankland, and A. Pithie

Gamma-interferon treatment for resistant oropharyngeal candidiasis in an HIV-positive patient
JAC Advance Access published on October 8, 2002
J. Antimicrob. Chemother. 2002 50: 765-766; doi:10.1093/jac/dkf206 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Book reviews:

Peter Davey

Oxford Textbook of Clinical Pharmacology and Drug Therapy, Third Edition
J. Antimicrob. Chemother. 2002 50: 767-768; doi:10.1093/jac/dkf202 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

J. D. Williams

Macrolide Antibiotics
J. Antimicrob. Chemother. 2002 50: 768-769; doi:10.1093/jac/dkf189 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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