Journal of Antimicrobial Chemotherapy

Editorial:

David S. Reeves and Colin W. E. Drummond

JAC Advance Access—accelerated online publication (www.jac.oupjournals.org)
J. Antimicrob. Chemother. 2002 50: 443-444; doi:10.1093/jac/dkf228 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Pannika Niumsup and Vanaporn Wuthiekanun

Cloning of the class D ß-lactamase gene from Burkholderia pseudomallei and studies on its expression in ceftazidime-susceptible and -resistant strains
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 445-455; doi:10.1093/jac/dkf165 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Pier Carlo Braga and Davide Ricci

Differences in the susceptibility of Streptococcus pyogenes to rokitamycin and erythromycin A revealed by morphostructural atomic force microscopy
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 457-460; doi:10.1093/jac/dkf180 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Hilde Ulvatne, Hanne Husom Haukland, Ørjan Samuelsen, Manuela Krämer, and Lars H. Vorland

Proteases in Escherichia coli and Staphylococcus aureus confer reduced susceptibility to lactoferricin B
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 461-467; doi:10.1093/jac/dkf156 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Masayuki Niwa, Yutaka Kanamori, Koichi Hotta, Hiroyuki Matsuno, Osamu Kozawa, Sadaki Fujimoto, and Toshihiko Uematsu

Priming by grepafloxacin on respiratory burst of human neutrophils: its possible mechanism
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 469-478; doi:10.1093/jac/dkf160 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jennifer Andrews, Rebecca Walker, Anna King, and for the BSAC Working Party on Sensitivity Testing

Evaluation of media available for testing the susceptibility of Pseudomonas aeruginosa by BSAC methodology
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 479-486; doi:10.1093/jac/dkf181 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Beilei Ge, Sonya Bodeis, Robert D. Walker, David G. White, Shaohua Zhao, Patrick F. McDermott, and Jianghong Meng

Comparison of the Etest and agar dilution for in vitro antimicrobial susceptibility testing of Campylobacter
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 487-494; doi:10.1093/jac/dkf162 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

F. J. Boswell, J. M. Andrews, G. Jevons, and R. Wise

Comparison of the in vitro activities of several new fluoroquinolones against respiratory pathogens and their abilities to select fluoroquinolone resistance
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 495-502; doi:10.1093/jac/dkf152 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jing-Jou Yan, Wen-Chien Ko, Chin-Luan Chuang, and Jiunn-Jong Wu

Metallo-ß-lactamase-producing Enterobacteriaceae isolates in a university hospital in Taiwan: prevalence of IMP-8 in Enterobacter cloacae and first identification of VIM-2 in Citrobacter freundii
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 503-511; doi:10.1093/jac/dkf170 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M. B. Kerrn, T. Klemmensen, N. Frimodt-Møller, and F. Espersen

Susceptibility of Danish Escherichia coli strains isolated from urinary tract infections and bacteraemia, and distribution of sul genes conferring sulphonamide resistance
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 513-516; doi:10.1093/jac/dkf164 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Christoph Steininger, Franz Allerberger, and Erich Gnaiger

Clinical significance of inhibition kinetics for Streptococcus pyogenes in response to penicillin
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 517-523; doi:10.1093/jac/dkf174 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

F. J. Boswell, J. P. Ashby, J. M. Andrews, and R. Wise

Effect of protein binding on the in vitro activity and pharmacodynamics of faropenem
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 525-532; doi:10.1093/jac/dkf155 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Alexander A. Firsov, Stephen H. Zinner, Sergey N. Vostrov, Yury A. Portnoy, and Irene Yu. Lubenko

AUC/MIC relationships to different endpoints of the antimicrobial effect: multiple-dose in vitro simulations with moxifloxacin and levofloxacin
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 533-539; doi:10.1093/jac/dkf177 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

S. Perez, C. Solans, M. A. Bregante, I. Pinilla, M. A. García, and F. Honrubia

Pharmacokinetics and ocular penetration of grepafloxacin in albino and pigmented rabbits
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 541-545; doi:10.1093/jac/dkf178 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Kazunari Tominaga, Kazuhide Higuchi, Norio Hamasaki, Masaki Hamaguchi, Takashi Takashima, Tetsuya Tanigawa, Toshio Watanabe, Yasuhiro Fujiwara, Yasuhiro Tezuka, Takema Nagaoka, Shigetoshi Kadota, Eiji Ishii, Kazuo Kobayashi, and Tetsuo Arakawa

In vivo action of novel alkyl methyl quinolone alkaloids against Helicobacter pylori
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 547-552; doi:10.1093/jac/dkf159 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. Aminimanizani, P. M. Beringer, J. Kang, L. Tsang, R. W. Jelliffe, and B. J. Shapiro

Distribution and elimination of tobramycin administered in single or multiple daily doses in adult patients with cystic fibrosis
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 553-559; doi:10.1093/jac/dkf168 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

The Campylobacter Sentinel Surveillance Scheme Collaborators

Ciprofloxacin resistance in Campylobacter jejuni: case–case analysis as a tool for elucidating risks at home and abroad
J. Antimicrob. Chemother. 2002 50: 561-568; doi:10.1093/jac/dkf173 [Abstract] [FREE Full Text] [PDF] Supplementary data [Request Permissions]  

Albert Sotto, Jean Yves Lefrant, Pascale Fabbro-Peray, Laurent Muller, Jérôme Tafuri, Francis Navarro, Michel Prudhomme, and Jean Emmanuel de La Coussaye

Evaluation of antimicrobial therapy management of 120 consecutive patients with secondary peritonitis
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 569-576; doi:10.1093/jac/dkf167 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jonathan A. T. Sandoe, Ian R. Witherden, Ho-Kong C. Au-Yeung, Peter Kite, Kevin G. Kerr, and Mark H. Wilcox

Enterococcal intravascular catheter-related bloodstream infection: management and outcome of 61 consecutive cases
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 577-582; doi:10.1093/jac/dkf182 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

E. R. Meaden, P. G. Hoggard, P. Newton, J. F. Tjia, D. Aldam, D. Cornforth, J. Lloyd, I. Williams, D. J. Back, and S. H. Khoo

P-glycoprotein and MRP1 expression and reduced ritonavir and saquinavir accumulation in HIV-infected individuals
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 583-588; doi:10.1093/jac/dkf161 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

A. K. Reinhardt, I. Kempf, M. Kobisch, and A. V. Gautier-Bouchardon

Fluoroquinolone resistance in Mycoplasma gallisepticum: DNA gyrase as primary target of enrofloxacin and impact of mutations in topoisomerases on resistance level
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 589-592; doi:10.1093/jac/dkf158 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ayush Kumar and Elizabeth A. Worobec

Fluoroquinolone resistance of Serratia marcescens: involvement of a proton gradient-dependent efflux pump
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 593-596; doi:10.1093/jac/dkf147 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

David C. Bean and John D. Klena

Prevalence of erm(A) and mef(B) erythromycin resistance determinants in isolates of Streptococcus pneumoniae from New Zealand
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 597-599; doi:10.1093/jac/dkf169 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

P. Zapater, S. Reus, A. Tello, D. Torrús, M. Pérez-Mateo, and J. F. Horga

A prospective study of the clarithromycin–digoxin interaction in elderly patients
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 601-606; doi:10.1093/jac/dkf176 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Marc Leone, Emmanuelle Sampol-Manos, Dominique Santelli, Stéphanie Grabowski, Bernard Alliez, Alain Durand, Bruno Lacarelle, and Claude Martin

Brain tissue penetration of ciprofloxacin following a single intravenous dose
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 607-609; doi:10.1093/jac/dkf179 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

Manuela Caniça, Ricardo Dias, Deolinda Louro, Catarina Carvalho, and the Multicentre Study Group

In vitro activity of extended-spectrum cephalosporins against Streptococcus pneumoniae strains with reduced susceptibility to penicillin isolated from patients in Portugal between 1995 and 2000
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 611-612; doi:10.1093/jac/dkf175 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Kay L. Goodyear

Veterinary surveillance for antimicrobial resistance
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 612-614; doi:10.1093/jac/dkf154 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

P. Dellamonica

Preventing the risk of emergence of bacterial resistance associated with antibiotic therapy: what role for pharmacokinetic and pharmacodynamic data?
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 614-615; doi:10.1093/jac/dkf166 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

E. Bailey, N. Berry, and J. S. Cheesbrough

Antimicrobial lock therapy for catheter-related bacteraemia among patients on maintenance haemodialysis
JAC Advance Access published on September 20, 2002
J. Antimicrob. Chemother. 2002 50: 615-617; doi:10.1093/jac/dkf183 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Toshiaki Shimizu, Hidenori Haruna, Ken Hisada, and Yuichiro Yamashiro

Effects of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in children
JAC Advance Access published on September 6, 2002
J. Antimicrob. Chemother. 2002 50: 617-618; doi:10.1093/jac/dkf157 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Book review:

Alan Johnson

Antibiotic Development and Resistance
J. Antimicrob. Chemother. 2002 50: 619; doi:10.1093/jac/dkf171 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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