Journal of Antimicrobial Chemotherapy

Leading articles:

Tuofu Zhu

HIV-1 in peripheral blood monocytes: an underrated viral source
J. Antimicrob. Chemother. 2002 50: 309-311; doi:10.1093/jac/dkf143 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Frances G. O’Brien, Christopher Price, Warren B. Grubb, and John E. Gustafson

Genetic characterization of the fusidic acid and cadmium resistance determinants of Staphylococcus aureus plasmid pUB101
J. Antimicrob. Chemother. 2002 50: 313-321; doi:10.1093/jac/dkf153 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

B. Heym, M. Le Moal, L. Armand-Lefevre, and M.-H. Nicolas-Chanoine

Multilocus sequence typing (MLST) shows that the ‘Iberian’ clone of methicillin-resistant Staphylococcus aureus has spread to France and acquired reduced susceptibility to teicoplanin
J. Antimicrob. Chemother. 2002 50: 323-329; doi:10.1093/jac/dkf132 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Matthew B. Avison and Alan M. Simm

Sequence and genome context analysis of a new molecular class D ß-lactamase gene from Legionella pneumophila
J. Antimicrob. Chemother. 2002 50: 331-338; doi:10.1093/jac/dkf135 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Sabrina Pacor, Anna Giangaspero, Marina Bacac, Gianni Sava, and Alessandro Tossi

Analysis of the cytotoxicity of synthetic antimicrobial peptides on mouse leucocytes: implications for systemic use
J. Antimicrob. Chemother. 2002 50: 339-348; doi:10.1093/jac/dkf141 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Delphine Croisier, Pascal Chavanet, Catherine Lequeu, Abderrahmane Ahanou, Anne Nierlich, Catherine Neuwirth, Lionel Piroth, Michel Duong, Marielle Buisson, and Henri Portier

Efficacy and pharmacodynamics of simulated human-like treatment with levofloxacin on experimental pneumonia induced with penicillin-resistant pneumococci with various susceptibilities to fluoroquinolones
J. Antimicrob. Chemother. 2002 50: 349-360; doi:10.1093/jac/dkf131 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

David A. Stevens, Leilani Calderon, Martha Martinez, Karl V. Clemons, Shelly J. Wilson, and Claude P. Selitrennikoff

Zeamatin, clotrimazole and nikkomycin Z in therapy of a Candida vaginitis model
J. Antimicrob. Chemother. 2002 50: 361-364; doi:10.1093/jac/dkf136 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Luigia Rossi, Sabrina Dominici, Sonja Serafini, Anna Casabianca, Aurora Cerasi, Laura Chiarantini, Angela Gabriela Celeste, Loredana Cappellacci, Palmarisa Franchetti, Mario Grifantini, and Mauro Magnani

Pharmacokinetic and antiretroviral activity in mice of oral [P¹,P²-bis[2-(adenin-9-yl)ethoxymethyl]phosphonate], a prodrug of 9-(2-phosphonylmethoxyethyl)adenine
J. Antimicrob. Chemother. 2002 50: 365-374; doi:10.1093/jac/dkf125 [Abstract] [FREE Full Text] [PDF] Erratum [Request Permissions]  

Mario Tumbarello, Katleen de Gaetano Donati, Evelina Tacconelli, Rita Citton, Teresa Spanu, Fiammetta Leone, Giovanni Fadda, and Roberto Cauda

Risk factors and predictors of mortality of methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia in HIV-infected patients
J. Antimicrob. Chemother. 2002 50: 375-382; doi:10.1093/jac/dkf126 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Olivier Denis, Claire Nonhoff, Baudouin Byl, Christiane Knoop, Sophie Bobin-Dubreux, and Marc J. Struelens

Emergence of vancomycin-intermediate Staphylococcus aureus in a Belgian hospital: microbiological and clinical features
J. Antimicrob. Chemother. 2002 50: 383-391; doi:10.1093/jac/dkf142 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Anna Baraniak, Janusz Fiett, Waleria Hryniewicz, Patrice Nordmann, and Marek Gniadkowski

Ceftazidime-hydrolysing CTX-M-15 extended-spectrum ß-lactamase (ESBL) in Poland
J. Antimicrob. Chemother. 2002 50: 393-396; doi:10.1093/jac/dkf151 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Dilek Colak, Thierry Naas, Filiz Gunseren, Nicolas Fortineau, Dilara Ogunc, Meral Gultekin, and Patrice Nordmann

First outbreak of vancomycin-resistant enterococci in a tertiary hospital in Turkey
J. Antimicrob. Chemother. 2002 50: 397-401; doi:10.1093/jac/dkf134 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

K. Weiss, C. Guilbault, L. Cortes, C. Restieri, D. E. Low, and the EQUERE project (Etude QUEbecoise des pathogènes REspiratoires)

Genotypic characterization of macrolide-resistant strains of Streptococcus pneumoniae isolated in Quebec, Canada, and in vitro activity of ABT-773 and telithromycin
J. Antimicrob. Chemother. 2002 50: 403-406; doi:10.1093/jac/dkf146 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M. Donati, G. M. Pollini, M. Sparacino, M. T. Fortugno, E. Laghi, and R. Cevenini

Comparative in vitro activity of garenoxacin against Chlamydia spp.
J. Antimicrob. Chemother. 2002 50: 407-410; doi:10.1093/jac/dkf145 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ellie J. C. Goldstein, Diane M. Citron, C. Vreni Merriam, Yumi A. Warren, Kerin L. Tyrrell, and Helen T. Fernandez

Comparative in vitro activity of faropenem and 11 other antimicrobial agents against 405 aerobic and anaerobic pathogens isolated from skin and soft tissue infections from animal and human bites
J. Antimicrob. Chemother. 2002 50: 411-420; doi:10.1093/jac/dkf139 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Kurt Fuursted and Helga Schumacher

Significance of low-level resistance to ciprofloxacin in Klebsiella pneumoniae and the effect of increased dosage of ciprofloxacin in vivo using the rat granuloma pouch model
J. Antimicrob. Chemother. 2002 50: 421-424; doi:10.1093/jac/dkf148 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Vincent H. Tam, Peggy S. McKinnon, Ronda L. Akins, Michael J. Rybak, and George L. Drusano

Pharmacodynamics of cefepime in patients with Gram-negative infections
J. Antimicrob. Chemother. 2002 50: 425-428; doi:10.1093/jac/dkf130 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Grant W. Howard, Evan J. Begg, Stephen T. Chambers, Jane Vella Brincat, Mei Zhang, and Carl M. J. Kirkpatrick

Free and total cefazolin plasma and interstitial fluid concentrations at steady state during continuous infusion
J. Antimicrob. Chemother. 2002 50: 429-432; doi:10.1093/jac/dkf129 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

J. M. Andrews, R. Wise, and on behalf of the BSAC Working Party on Sensitivity Training

Reply to: Ciprofloxacin susceptibility testing of enterococcal urinary isolates in accordance with BSAC guidelines
J. Antimicrob. Chemother. 2002 50: 433; doi:10.1093/jac/dkf127 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Branko Kopjar

Azithromycin is effective in patients with chronic bronchitis
J. Antimicrob. Chemother. 2002 50: 433-434; doi:10.1093/jac/dkf114 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Despina G. Contopoulos-Ioannidis, John P. A. Ioannidis, and Joseph Lau

Reply
J. Antimicrob. Chemother. 2002 50: 434; doi:10.1093/jac/dkf120 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Brendan Crowley

Ganciclovir treatment of symptomatic congenital cytomegalovirus infection
J. Antimicrob. Chemother. 2002 50: 435-436; doi:10.1093/jac/dkf144 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Paul D. Griffiths

Reply
J. Antimicrob. Chemother. 2002 50: 436; doi:10.1093/jac/dkf149 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Carmen Betriu, Esther Culebras, Montserrat Redondo, Iciar Rodríguez-Avial, María Gómez, Ana Boloix, and Juan J. Picazo

Prevalence of macrolide and tetracycline resistance mechanisms in Streptococcus pyogenes isolates and in vitro susceptibility to telithromycin
J. Antimicrob. Chemother. 2002 50: 436-438; doi:10.1093/jac/dkf128 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

P. G. Higgins, A. C. Fluit, D. Hafner, J. Verhoef, and F.-J. Schmitz

Evidence of cross-resistance between ciprofloxacin and non-fluoroquinolones in European Gram-negative clinical isolates
J. Antimicrob. Chemother. 2002 50: 438-440; doi:10.1093/jac/dkf150 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Lewis V. Buchanan, Charlene F. Dailey, Richelle J. LeMay, Raymond J. Zielinski, Ming-Shang T. Kuo, and John K. Gibson

Time-dependent antibacterial effects of linezolid in experimental rabbit endocarditis
J. Antimicrob. Chemother. 2002 50: 440-442; doi:10.1093/jac/dkf138 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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