Journal of Antimicrobial Chemotherapy

Leading articles:

Pietro E. Varaldo

Antimicrobial resistance and susceptibility testing: an evergreen topic
J. Antimicrob. Chemother. 2002 50: 1-4; doi:10.1093/jac/dkf093 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Review:

Jan Balzarini and Christopher McGuigan

Bicyclic pyrimidine nucleoside analogues (BCNAs) as highly selective and potent inhibitors of varicella-zoster virus replication
J. Antimicrob. Chemother. 2002 50: 5-9; doi:10.1093/jac/dkf037 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Frédéric Bert, Catherine Branger, and Nicole Lambert-Zechovsky

Identification of PSE and OXA ß-lactamase genes in Pseudomonas aeruginosa using PCR–restriction fragment length polymorphism
J. Antimicrob. Chemother. 2002 50: 11-18; doi:10.1093/jac/dkf069 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Renee-Claude Mercier, Carmine Stumpo, and Michael J. Rybak

Effect of growth phase and pH on the in vitro activity of a new glycopeptide, oritavancin (LY333328), against Staphylococcus aureus and Enterococcus faecium
J. Antimicrob. Chemother. 2002 50: 19-24; doi:10.1093/jac/dkf058 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

J. C. P. Steele, R. J. Phelps, M. S. J. Simmonds, D. C. Warhurst, and D. J. Meyer

Two novel assays for the detection of haemin-binding properties of antimalarials evaluated with compounds isolated from medicinal plants
J. Antimicrob. Chemother. 2002 50: 25-31; doi:10.1093/jac/dkf089 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Catherine L. Clark, Kensuke Nagai, Bonifacio E. Dewasse, Glenn A. Pankuch, Lois M. Ednie, Michael R. Jacobs, and Peter C. Appelbaum

Activity of cefditoren against respiratory pathogens
J. Antimicrob. Chemother. 2002 50: 33-41; doi:10.1093/jac/dkf076 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

J. Flamaing, J. Verhaegen, and W. E. Peetermans

Streptococcus pneumoniae bacteraemia in Belgium: differential characteristics in children and the elderly population and implications for vaccine use
J. Antimicrob. Chemother. 2002 50: 43-50; doi:10.1093/jac/dkf086 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Murli U. Purswani, Susan J. Eckert, Harman K. Arora, and Gary J. Noel

Effect of ciprofloxacin on lethal and sublethal challenge with endotoxin and on early cytokine responses in a murine in vivo model
J. Antimicrob. Chemother. 2002 50: 51-58; doi:10.1093/jac/dkf091 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Takao Kobayashi, Kazuhiro Tateda, Tetsuya Matsumoto, Shuichi Miyazaki, Akira Watanabe, Toshihiro Nukiwa, and Keizo Yamaguchi

Macrolide-treated Pseudomonas aeruginosa induces paradoxical host responses in the lungs of mice and a high mortality rate
J. Antimicrob. Chemother. 2002 50: 59-66; doi:10.1093/jac/dkf048 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M. Dolores Sánchez Navarro, M. Luisa Sayalero Marinero, and Amparo Sánchez Navarro

Pharmacokinetic/pharmacodynamic modelling of ciprofloxacin 250 mg/12 h versus 500 mg/24 h for urinary infections
J. Antimicrob. Chemother. 2002 50: 67-72; doi:10.1093/jac/dkf079 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. M. Lovering, J. Zhang, G. C. Bannister, B. J. A. Lankester, J. H. M. Brown, G. Narendra, and A. P. MacGowan

Penetration of linezolid into bone, fat, muscle and haematoma of patients undergoing routine hip replacement
J. Antimicrob. Chemother. 2002 50: 73-77; doi:10.1093/jac/dkf066 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Miguel A. Sanz, Javier López, Juan J. Lahuerta, Montserrat Rovira, Montserrat Batlle, Cristina Pérez, Lourdes Vázquez, Antonio Julià, Javier Palau, Martín Gutiérrez, Francisco J. Capote, Fernando Ramos, Luis Benlloch, Luis Larrea, Isidro Jarque, and for the Spanish PETHEMA Group

Cefepime plus amikacin versus piperacillin–tazobactam plus amikacin for initial antibiotic therapy in haematology patients with febrile neutropenia: results of an open, randomized, multicentre trial
J. Antimicrob. Chemother. 2002 50: 79-88; doi:10.1093/jac/dkf087 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Alan P. Johnson, Marina Warner, and David M. Livermore

In vitro activity of a novel oxazolidinone, AZD2563, against randomly selected and multiresistant Gram-positive cocci
J. Antimicrob. Chemother. 2002 50: 89-93; doi:10.1093/jac/dkf068 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Mihaela Peric, Gengrong Lin, Catherine L. Clark, Michael R. Jacobs, and Peter C. Appelbaum

Antipneumococcal activity of AZD2563, a new oxazolidinone, compared with nine other agents
J. Antimicrob. Chemother. 2002 50: 95-100; doi:10.1093/jac/dkf080 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Lois M. Ednie, Michael R. Jacobs, and Peter C. Appelbaum

Anti-anaerobic activity of AZD2563, a new oxazolidinone, compared with eight other agents
J. Antimicrob. Chemother. 2002 50: 101-105; doi:10.1093/jac/dkf088 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Steven J. McCann, Leslie O. White, and Brian Keevil

Assay of teicoplanin in serum: comparison of high-performance liquid chromatography and fluorescence polarization immunoassay
J. Antimicrob. Chemother. 2002 50: 107-110; doi:10.1093/jac/dkf067 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

E. Lucile White, William J. Suling, Larry J. Ross, Lainne E. Seitz, and Robert C. Reynolds

2-Alkoxycarbonylaminopyridines: inhibitors of Mycobacterium tuberculosis FtsZ
J. Antimicrob. Chemother. 2002 50: 111-114; doi:10.1093/jac/dkf075 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

P.-M. Rath, J. M. Freise, and R. Ansorg

Susceptibility testing of Aspergillus spp. by means of an automated blood culture system
J. Antimicrob. Chemother. 2002 50: 115-117; doi:10.1093/jac/dkf073 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M. Laverdiere, D. Hoban, C. Restieri, and F. Habel

In vitro activity of three new triazoles and one echinocandin against Candida bloodstream isolates from cancer patients
J. Antimicrob. Chemother. 2002 50: 119-123; doi:10.1093/jac/dkf074 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

C. von Hunolstein, F. Scopetti, A. Efstratiou, and K. Engler

Penicillin tolerance amongst non-toxigenic Corynebacterium diphtheriae isolated from cases of pharyngitis
J. Antimicrob. Chemother. 2002 50: 125-128; doi:10.1093/jac/dkf107 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Intetsu Kobayashi, Hiroe Muraoka, Miyuki Hasegawa, Takeshi Saika, Minoru Nishida, Makoto Kawamura, and Ryoichi Ando

In vitro anti-Helicobacter pylori activity of BAS-118, a new benzamide derivative
J. Antimicrob. Chemother. 2002 50: 129-132; doi:10.1093/jac/dkf106 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Tetsufumi Koga, Harumi Inoue, Chika Ishii, Yoko Okazaki, Haruki Domon, and Yukio Utsui

Effect of plaunotol in combination with clarithromycin or amoxicillin on Helicobacter pylori in vitro and in vivo
J. Antimicrob. Chemother. 2002 50: 133-136; doi:10.1093/jac/dkf094 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

Peter Gilbert, Andrew J. McBain, and Sally F. Bloomfield

Biocide abuse and antimicrobial resistance: being clear about the issues
J. Antimicrob. Chemother. 2002 50: 137-139; doi:10.1093/jac/dkf071 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Adam P. Fraise

Reply
J. Antimicrob. Chemother. 2002 50: 139-140; doi:10.1093/jac/dkf070 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Lourdes Valera, Elizabeth Gradelski, Elizabeth Huczko, Thomas Washo, Hesna Yigit, and Joan Fung-Tomc

In vitro activity of a novel des-fluoro(6) quinolone, garenoxacin (BMS-284756), against rapidly growing mycobacteria and Nocardia isolates
J. Antimicrob. Chemother. 2002 50: 140-142; doi:10.1093/jac/dkf081 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

H. Liddy and R. Holliman

Group B Streptococcus highly resistant to gentamicin
J. Antimicrob. Chemother. 2002 50: 142-143; doi:10.1093/jac/dkf090 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Thomas Butler

Reduction of MIC of azithromycin for Salmonella typhi and Staphylococcus aureus in broth exposed to previous growth of Salmonella typhi
J. Antimicrob. Chemother. 2002 50: 143-145; doi:10.1093/jac/dkf064 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

F.-J. Schmitz, S. Schwarz, D. Milatovic, J. Verhoef, and A. C. Fluit

In vitro activities of the ketolides ABT-773 and telithromycin and of three macrolides against genetically characterized isolates of Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae and Moraxella catarrhalis
J. Antimicrob. Chemother. 2002 50: 145-148; doi:10.1093/jac/dkf085 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Book review:

E. W. Odell

Peptide Antibiotics. Discovery, Modes of Action and Applications
J. Antimicrob. Chemother. 2002 50: 149; doi:10.1093/jac/dkf078 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Erratum:

H. Lode and M. Allewelt

Role of newer fluoroquinolones in lower respiratory tract infections
J. Antimicrob. Chemother. 2002 50: 151-154; doi:10.1093/jac/dkf133 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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