Journal of Antimicrobial Chemotherapy

Leading articles:

A. M. CLARKE

Prophylactic antibiotics for total hip arthroplasty—the significance of Staphylococcus epidermidis
J. Antimicrob. Chemother. 1979 5: 493-495; doi:10.1093/jac/5.5.493 [PDF] [Request Permissions]  

M. W. MCKENDRICK

Erythromycin revisited
J. Antimicrob. Chemother. 1979 5: 495-497; doi:10.1093/jac/5.5.495 [PDF] [Request Permissions]  

DONALD A. LEIGH

Treatment of familial staphytococcal infection
J. Antimicrob. Chemother. 1979 5: 497-499; doi:10.1093/jac/5.5.497 [PDF] [Request Permissions]  

DAVID I. EDWARDS

Mechanism of antimicrobial action of metronidazole
J. Antimicrob. Chemother. 1979 5: 499-502; doi:10.1093/jac/5.5.499 [PDF] [Request Permissions]  

Review article:

L. Curcio

Optimal dosage regimen for penicillins: bolus or continuous infusion?
J. Antimicrob. Chemother. 1979 5: 503-509; doi:10.1093/jac/5.5.503 [PDF] [Request Permissions]  

Original articles:

M. J. Greenall, K. Froome, Mary Evans, and A. V. Pollock

The influence of intra-incisional clindamycin on the incidence of wound sepsis after abdominal operations
J. Antimicrob. Chemother. 1979 5: 511-516; doi:10.1093/jac/5.5.511 [Abstract] [PDF] [Request Permissions]  

C. J. Ellis, A. M. Geddes, P. G. Darey, R. Wise, J. M Andrews, and R. P. Grimley

Mezlocillin and azlocillin: an evaluation of two new ß-lactam antibiotics
J. Antimicrob. Chemother. 1979 5: 517-525; doi:10.1093/jac/5.5.517 [Abstract] [PDF] [Request Permissions]  

Susan V. Want, Rosamond A. K. Jones, and John H. Darrell

Amikacin dosage in the preterm newborn
J. Antimicrob. Chemother. 1979 5: 527-530; doi:10.1093/jac/5.5.527 [Abstract] [PDF] [Request Permissions]  

Y. Arabi, Frances Dimock, D. W. Burdon, J. Alexander-Williams, and M. R. B. Keighley

Influence of neomycin and metronidazole on colonic microflora of volunteers
J. Antimicrob. Chemother. 1979 5: 531-537; doi:10.1093/jac/5.5.531 [Abstract] [PDF] [Request Permissions]  

David Greenwood, Francis O'Grady, and Paul Baker

An in vitro evaluation of clavulanic acid, a potent, broad-spectrum ß-lactamase inhibitor
J. Antimicrob. Chemother. 1979 5: 539-547; doi:10.1093/jac/5.5.539 [Abstract] [PDF] [Request Permissions]  

B. Chattopadhyay and L. Hall

In vitro combination of mecillinam with cephradine or amoxycillin for organisms resistant to single agents
J. Antimicrob. Chemother. 1979 5: 549-553; doi:10.1093/jac/5.5.549 [Abstract] [PDF] [Request Permissions]  

Theodor Elmros, Stig Holm, Erik Kjellberg, Staffan Normark, and Bengt Winblad

Effects of low ampicillin concentrations on penicillin sensitive and ß-lactamase producing strains of Neisseria gonorrhoeae
J. Antimicrob. Chemother. 1979 5: 555-561; doi:10.1093/jac/5.5.555 [Abstract] [PDF] [Request Permissions]  

Uwe UIlmann

Bacteriological studies with cefsulodin (CGP 7174/E), the first antipseadomonal cephalosporin
J. Antimicrob. Chemother. 1979 5: 563-567; doi:10.1093/jac/5.5.563 [Abstract] [PDF] [Request Permissions]  

A. Kathrine Miller, Evemarie Celozzi, Barbara Ann Pelak, Jerome Birnbaum, and Edward O. Stapley

Correlation of in vitro susceptibility with in vivo efficacy in mice for cefoxitin in comparison with cephalosporins
J. Antimicrob. Chemother. 1979 5: 569-579; doi:10.1093/jac/5.5.569 [Abstract] [PDF] [Request Permissions]  

H. Giamarellou, Ch. Metzikoff, S. Papachristophorou, A. S. Dontas, and G. K. Daikos

Prospective comparative evaluation of gentamicin or gentamicin plus cephalothin in the production of nephrotoxicity in man
J. Antimicrob. Chemother. 1979 5: 581-590; doi:10.1093/jac/5.5.581 [Abstract] [PDF] [Request Permissions]  

Anna-Stina Malmborg

Effect of food on absorption of erythromycin. A study of two derivatives, the stearate and the base
J. Antimicrob. Chemother. 1979 5: 591-599; doi:10.1093/jac/5.5.591 [Abstract] [PDF] [Request Permissions]  

R. Wise, J. M. Andrews, S. Dean, P. G. Welling, and M. J. Kendall

A pharmacological and in vitro comparison of three oral cephalosporins
J. Antimicrob. Chemother. 1979 5: 601-607; doi:10.1093/jac/5.5.601 [Abstract] [PDF] [Request Permissions]  

Correspondence:

DAVID GREENWOOD, NEIL PEARSON, PAUL BAKER, and FRANCIS O'GRADY

In vitro activity of cefotaxime
J. Antimicrob. Chemother. 1979 5: 609-610; doi:10.1093/jac/5.5.609 [PDF] [Request Permissions]  

J. A. GARCIA-RODRIGUEZ, F. MARTIN-LUENGO, and M. C. SAENZ-GONZALEZ

In vitro sensitivity of Nocardia asteroides to various aminogtycosides
J. Antimicrob. Chemother. 1979 5: 610-612; doi:10.1093/jac/5.5.610 [PDF] [Request Permissions]  

U. ULLMANN

Synergism between fosfomycin and nalidixic acid in vitro
J. Antimicrob. Chemother. 1979 5: 612-613; doi:10.1093/jac/5.5.612 [PDF] [Request Permissions]  

VICTOR LORIAN, RODGER P. SILLETTI, FRANK X. BIONDO, and CICERO C. DE FREITAS

Paradoxical effect of aminoglycoside antibiotics on the growth of Gram-negative bacilli
J. Antimicrob. Chemother. 1979 5: 613-616; doi:10.1093/jac/5.5.613 [PDF] [Request Permissions]  

J. A. GARCIA-RODRIGUEZ, A. C. GOMEZ-GARCIA, and F. MARTIN-LUENGO

In vitro activity of cefoxitin against Nocardia spp. and Actinomadura spp.
J. Antimicrob. Chemother. 1979 5: 616-618; doi:10.1093/jac/5.5.616 [PDF] [Request Permissions]  

THOMAS T. YOSHIKAWA and SHARON A. SHIBATA

In vitro susceptibility of penicillianse-producing Neisseria gonorrhoeae to a select group of antimicrobial agents, alone and in combination
J. Antimicrob. Chemother. 1979 5: 618-620; doi:10.1093/jac/5.5.618 [PDF] [Request Permissions]  

M. N. LOGAN, R. WISE, and R. P. GRIMLEY

Biliary levels of cefoxitin
J. Antimicrob. Chemother. 1979 5: 620-621; doi:10.1093/jac/5.5.620 [PDF] [Request Permissions]  

G. W. HOUGHTON, J. SMITH, P. S. THORNE, and R. TEMPLETON

The pharmacokinetics of oral and intravenous metronidazole in man
J. Antimicrob. Chemother. 1979 5: 621-623; doi:10.1093/jac/5.5.621 [PDF] [Request Permissions]  

Errata:

L. R. Peterson, D. N. Gerding, D. McLinn, and W. H. Hall

Prediction of peak penicillin and cephalosporin concentrations in canine serum as derived from in vitro serum and tissue quantitative protein binding
J. Antimicrob. Chemother. 1979 5: 623; doi:10.1093/jac/5.5.623 [Abstract] [PDF] [Request Permissions]  

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