Journal of Antimicrobial Chemotherapy

Leading articles:

H. LAMBERT

Antimicrobial drugs in the treatment and prevention of pertussis
J. Antimicrob. Chemother. 1979 5: 329-331; doi:10.1093/jac/5.4.329 [PDF] [Request Permissions]  

HAROLD C. NEU

Prophylaxis—has it at last come of age?
J. Antimicrob. Chemother. 1979 5: 331-333; doi:10.1093/jac/5.4.331 [PDF] [Request Permissions]  

J. S. OXFORD

Inhibition of herpes virus by a new compound—acyclic guanosine
J. Antimicrob. Chemother. 1979 5: 333-334; doi:10.1093/jac/5.4.333 [PDF] [Request Permissions]  

C. C. EVANS

Management of pulmonary disorders caused by the inhalation of aspergillus spores
J. Antimicrob. Chemother. 1979 5: 335-336; doi:10.1093/jac/5.4.335 [PDF] [Request Permissions]  

Review article:

Stephen P. Barrett and Peter J. Watt

Antibiotics and the liver
J. Antimicrob. Chemother. 1979 5: 337-348; doi:10.1093/jac/5.4.337 [PDF] [Request Permissions]  

M. Matthew

Plasmid-mediated ß-lactamases of Gram-negative bacteria: properties and distribution
J. Antimicrob. Chemother. 1979 5: 349-358; doi:10.1093/jac/5.4.349 [PDF] [Request Permissions]  

Original articles:

A. Kidson, H. A. Lilly, and E. J. L. Lowbury

Flucloxacillin treatment of methicillin-‘resistant’ and sensitive staphylococcal infection
J. Antimicrob. Chemother. 1979 5: 359-364; doi:10.1093/jac/5.4.359 [Abstract] [PDF] [Request Permissions]  

Jack Levy and Jean Klastersky

Synergism between amikacin and cefazolin against Staphylococcus aureus: a comparative study of oxacillin-sensitive and oxacillin-resistant strains
J. Antimicrob. Chemother. 1979 5: 365-373; doi:10.1093/jac/5.4.365 [Abstract] [PDF] [Request Permissions]  

Roger Labia, Christian Fabre, Jean-Michel Masson, Michel Barthelemy, Madeleine Heitz, and Jean-S. Pitton

Klebsiella pneumonia strains moderately resistant to ampicillin and carbenicillin: characterization of a new ß-lactamase
J. Antimicrob. Chemother. 1979 5: 375-382; doi:10.1093/jac/5.4.375 [Abstract] [PDF] [Request Permissions]  

Ole B. Jepsen, Ida Mortensen, and Vibeke Thamdrup Rosdahl

Screening methods for detection of ß-lactamases in Gram-negative bacteria
J. Antimicrob. Chemother. 1979 5: 383-389; doi:10.1093/jac/5.4.383 [Abstract] [PDF] [Request Permissions]  

Nigel A. C. Curtis, Gordon W. Ross, and Michael G. Bonlton

Effect of 7- methoxy substitution of cephalosporins upon their affinity for the penicillin-binding proteins of E. coti K12 Comparison with antibacterial activity and inhibition of membrane bound model transpeptidase activity
J. Antimicrob. Chemother. 1979 5: 391-398; doi:10.1093/jac/5.4.391 [Abstract] [PDF] [Request Permissions]  

Naomi Datta, Marilyn Nugent, Sebastian G. B. Amyes, and Paul McNeilly

Multiple mechanisms of trimethoprim resistance in strains of Escherichia coli from a patient treated with long-term co-trimoxazole
J. Antimicrob. Chemother. 1979 5: 399-406; doi:10.1093/jac/5.4.399 [Abstract] [PDF] [Request Permissions]  

James B. Malow, Victoria M. Zimelis, Hossein Pahlaranzadeh, G. Wesley White, Anand P. Panwalker, and George Gee Jackson

Comparative in vitro activity of Bay k 4999 and piperacillin
J. Antimicrob. Chemother. 1979 5: 407-412; doi:10.1093/jac/5.4.407 [Abstract] [PDF] [Request Permissions]  

M. Barnham and H. Gaya

In vitro susceptibility of urinary isolates of Escherichia coli to cinoxacin
J. Antimicrob. Chemother. 1979 5: 413-418; doi:10.1093/jac/5.4.413 [Abstract] [PDF] [Request Permissions]  

Pramod M. Shah, Gudrun Troche, and W. Stille

Effect of concentration on bactericidal activity of cefotaxime
J. Antimicrob. Chemother. 1979 5: 419-422; doi:10.1093/jac/5.4.419 [Abstract] [PDF] [Request Permissions]  

D. Merrikin and G. N. Rolinson

Antibiotic levels in experimentally infected mice in relation to therapeutic effect and antibacterial activity in vitro
J. Antimicrob. Chemother. 1979 5: 423-429; doi:10.1093/jac/5.4.423 [Abstract] [PDF] [Request Permissions]  

P. Collins and D. J. Bauer

The activity in vitro against herpes virus of 9-(2-hydroxyethoxymethyl)guanine (acycloguanosine), a new antiviral agent
J. Antimicrob. Chemother. 1979 5: 431-436; doi:10.1093/jac/5.4.431 [Abstract] [PDF] [Request Permissions]  

C. Strulovitch, M. I. Marks, A. Soneji, and S. Goldberg

Immunotherapy and drugs in neonatal disseminated herpes simplex virus type 2 infections: a mouse model
J. Antimicrob. Chemother. 1979 5: 437-446; doi:10.1093/jac/5.4.437 [Abstract] [PDF] [Request Permissions]  

R. P. Mouton, H. Mattie, K. Swart, J. Kreukniet, and J. de Wad

Blood levels of rifampicin, desacetylrifampicin and isoniazid during combined therapy
J. Antimicrob. Chemother. 1979 5: 447-454; doi:10.1093/jac/5.4.447 [Abstract] [PDF] [Request Permissions]  

Ian Alan Holder, Marsha Schwab, and Linda Jackson

Eighteen months of routine topical antimicrobial susceptibility testing of isolates from burn patients: results and conclusions
J. Antimicrob. Chemother. 1979 5: 455-463; doi:10.1093/jac/5.4.455 [Abstract] [PDF] [Request Permissions]  

Gary Gartenberg, Burt R. Meyers, Shalom Z. Hirschman, and Elina Srulevitch

Pharmacokinetics of cefaclor in patients with stable renal impairment, and patients undergoing haemodialysis
J. Antimicrob. Chemother. 1979 5: 465-470; doi:10.1093/jac/5.4.465 [Abstract] [PDF] [Request Permissions]  

Correspondence:

J. M. BROUGHALL, M. J. BYWATER, H. A. HOLT, and D. S. REEVES

Stabilization of cephalosporins in serum and plasma
J. Antimicrob. Chemother. 1979 5: 471-472; doi:10.1093/jac/5.4.471 [PDF] [Request Permissions]  

PETER BALL and JOHN GRAY

Activity of cefuroxime, cefoxitin and amikacin against Serratia marcesens
J. Antimicrob. Chemother. 1979 5: 472-473; doi:10.1093/jac/5.4.472 [PDF] [Request Permissions]  

A. D. RUSSELL and I. AHONKHAI

The antibacterial action of cefotaxime (HR 756)
J. Antimicrob. Chemother. 1979 5: 473-474; doi:10.1093/jac/5.4.473 [PDF] [Request Permissions]  

F. DASCHNER, E. BLUME, H. LANGMAACK, and W. WOLFART

Cefamandole concentrations in pulmonary and subcutaneous tissue
J. Antimicrob. Chemother. 1979 5: 474-475; doi:10.1093/jac/5.4.474 [PDF] [Request Permissions]  

JAIME R. TORRES-R, CHARLES V. SANDERS, and A. CARTER LEWIS

Vancomycin concentration in human tissues —preliminary report
J. Antimicrob. Chemother. 1979 5: 475-477; doi:10.1093/jac/5.4.475 [PDF] [Request Permissions]  

P. SANTANAM and F. H. KAYSER

An improved radioenzymatic assay of aminoglycoside antibiotics in haman serum by aminoglycoside 6'-N-acetyltransferase [AAC (6')]
J. Antimicrob. Chemother. 1979 5: 477-479; doi:10.1093/jac/5.4.477 [PDF] [Request Permissions]  

DAVID GREGORY, DOLORES ZELEZNIK, J. P. HARNISCH, and G. W. COUNTS

Activity of penicillin, erythromycin, and cephalosporins against isolates of Coryntbaeterimm diphtheriae from cutaneous lesions
J. Antimicrob. Chemother. 1979 5: 479-481; doi:10.1093/jac/5.4.479 [PDF] [Request Permissions]  

J. D. ANDERSON, M. Y. AIRD, A. M. JOHNSON, R. REE, D. GORESKY, C. A. BRUMWELL, and R. K. L. PERCIVAL-SMITH

The use of a single 1 g dose of amoxycillin for the treatment of acute urinary tract infections
J. Antimicrob. Chemother. 1979 5: 481-483; doi:10.1093/jac/5.4.481 [PDF] [Request Permissions]  

G. L. RIDGWAY and J. D. ORIEL

Activity of antimicrobials against Chlamydia trachomatis in vitro
J. Antimicrob. Chemother. 1979 5: 483-484; doi:10.1093/jac/5.4.483 [PDF] [Request Permissions]  

JANE SYMONDS

Secnidazole—a nitroimidazole with a prolonged serum half-life
J. Antimicrob. Chemother. 1979 5: 484-486; doi:10.1093/jac/5.4.484 [PDF] [Request Permissions]  

FIONA CROSFTLL and MARTIN L. CROSFILL

Antibiotic aerosols
J. Antimicrob. Chemother. 1979 5: 486-487; doi:10.1093/jac/5.4.486 [PDF] [Request Permissions]  

N. J. LEGAKIS, J. TSELENTIS, K. J. COURTIS, and J. PAPAVASSILIOU

Cross-resistance of clinical isolates of Pseudomonas aerntginosa to five aminoglycosides
J. Antimicrob. Chemother. 1979 5: 487-490; doi:10.1093/jac/5.4.487 [PDF] [Request Permissions]  

B. CHATTOPADHYAY and I. HALL

Antagonism between cefoxitin and cefuroxime
J. Antimicrob. Chemother. 1979 5: 490-491; doi:10.1093/jac/5.4.490 [PDF] [Request Permissions]  

MICHAEL R. ACHONG

Misuse of antimicrobial agents
J. Antimicrob. Chemother. 1979 5: 491; doi:10.1093/jac/5.4.491 [PDF] [Request Permissions]  

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