Journal of Antimicrobial Chemotherapy

Leading articles:

William Bishai

The in vivo–in vitro paradox in pneumococcal respiratory tract infections
J. Antimicrob. Chemother. 2002 49: 433-436; doi:10.1093/jac/49.3.433 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Reviews:

J. C. Graham and F. K. Gould

Role of aminoglycosides in the treatment of bacterial endocarditis
J. Antimicrob. Chemother. 2002 49: 437-444; doi:10.1093/jac/49.3.437 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Paul G. Ambrose, Robert C. Owens, Jr, Michael J. Garvey, and Ronald N. Jones

Pharmacodynamic considerations in the treatment of moderate to severe pseudomonal infections with cefepime
J. Antimicrob. Chemother. 2002 49: 445-453; doi:10.1093/jac/49.3.445 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Tetsumi Yamakawa, Junichi Mitsuyama, and Kazuya Hayashi

In vitro and in vivo antibacterial activity of T-3912, a novel non-fluorinated topical quinolone
J. Antimicrob. Chemother. 2002 49: 455-465; doi:10.1093/jac/49.3.455 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Peter C. Fuchs, Arthur L. Barry, and Steven D. Brown

In vitro bactericidal activity of daptomycin against staphylococci
J. Antimicrob. Chemother. 2002 49: 467-470; doi:10.1093/jac/49.3.467 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jordi Vila, Anna Ribera, Francesc Marco, Joaquim Ruiz, Josep Mensa, Josep Chaves, Gonzalo Hernandez, and M. Teresa Jimenez De Anta

Activity of clinafloxacin, compared with six other quinolones, against Acinetobacter baumannii clinical isolates
J. Antimicrob. Chemother. 2002 49: 471-477; doi:10.1093/jac/49.3.471 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Caroline J. Henwood, Tess Gatward, Marina Warner, Dorothy James, Mark W. Stockdale, Richard P. Spence, Kevin J. Towner, David M. Livermore, and Neil Woodford

Antibiotic resistance among clinical isolates of Acinetobacter in the UK, and in vitro evaluation of tigecycline (GAR-936)
J. Antimicrob. Chemother. 2002 49: 479-487; doi:10.1093/jac/49.3.479 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jung-A. Lim, Ae-Ran Kwon, Sook-Kyung Kim, Yunsop Chong, Kungwon Lee, and Eung-Chil Choi

Prevalence of resistance to macrolide, lincosamide and streptogramin antibiotics in Gram-positive cocci isolated in a Korean hospital
J. Antimicrob. Chemother. 2002 49: 489-495; doi:10.1093/jac/49.3.489 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. E. van den Bogaard, R. Willems, N. London, J. Top, and E. E. Stobberingh

Antibiotic resistance of faecal enterococci in poultry, poultry farmers and poultry slaughterers
J. Antimicrob. Chemother. 2002 49: 497-505; doi:10.1093/jac/49.3.497 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

J. Martínez-Lacasa, C. Cabellos, A. Martos, A. Fernández, F. Tubau, P. F. Viladrich, J. Liñares, and F. Gudiol

Experimental study of the efficacy of vancomycin, rifampicin and dexamethasone in the therapy of pneumococcal meningitis
J. Antimicrob. Chemother. 2002 49: 507-513; doi:10.1093/jac/49.3.507 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M. Martínez, J. L. López-Ribot, W. R. Kirkpatrick, S. P. Bachmann, S. Perea, M. T. Ruesga, and T. F. Patterson

Heterogeneous mechanisms of azole resistance in Candida albicans clinical isolates from an HIV-infected patient on continuous fluconazole therapy for oropharyngeal candidosis
J. Antimicrob. Chemother. 2002 49: 515-524; doi:10.1093/jac/49.3.515 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Montserrat Ortoneda, Javier Capilla, Isabel Pujol, F. Javier Pastor, Emilio Mayayo, Joan Fernández-Ballart, and Josep Guarro

Liposomal amphotericin B and granulocyte colony-stimulating factor therapy in a murine model of invasive infection by Scedosporium prolificans
J. Antimicrob. Chemother. 2002 49: 525-529; doi:10.1093/jac/49.3.525 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Ali A. Pahlevan, David J. M. Wright, Laura Bradley, Clive Smith, and Brian M. J. Foxwell

Potential of rifamides to inhibit TNF-induced NF-B activation
J. Antimicrob. Chemother. 2002 49: 531-534; doi:10.1093/jac/49.3.531 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M. Wootton, K. E. Bowker, H. A. Holt, and A. P. MacGowan

BAL 9141, a new broad-spectrum pyrrolidinone cephalosporin: activity against clinically significant anaerobes in comparison with 10 other antimicrobials
J. Antimicrob. Chemother. 2002 49: 535-539; doi:10.1093/jac/49.3.535 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Shigeru Fujimura, Seiichi Kato, Takeshi Kawamura, and Akira Watanabe

In vitro activity of rifampicin against Helicobacter pylori isolated from children and adults
J. Antimicrob. Chemother. 2002 49: 541-543; doi:10.1093/jac/49.3.541 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

L. Arreaza, C. Salcedo, B. Alcalá, and J. A. Vázquez

What about antibiotic resistance in Neisseria lactamica?
J. Antimicrob. Chemother. 2002 49: 545-547; doi:10.1093/jac/49.3.545 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Yan Zhi Qiang, Tong Qin, Wang Fu, Wu Pei Cheng, Yang Sheng Li, and Gong Yi

Use of a rapid mismatch PCR method to detect gyrA and parC mutations in ciprofloxacin-resistant clinical isolates of Escherichia coli
J. Antimicrob. Chemother. 2002 49: 549-552; doi:10.1093/jac/49.3.549 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ekaterina Pestova, John J. Millichap, Farida Siddiqui, Gary A. Noskin, and Lance R. Peterson

Non-PmrA-mediated multidrug resistance in Streptococcus pneumoniae
J. Antimicrob. Chemother. 2002 49: 553-556; doi:10.1093/jac/49.3.553 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Mark D. Reisbig and Nancy D. Hanson

The ACT-1 plasmid-encoded AmpC ß-lactamase is inducible: detection in a complex ß-lactamase background
J. Antimicrob. Chemother. 2002 49: 557-560; doi:10.1093/jac/49.3.557 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Laurent Poirel, Gerhard F. Weldhagen, Christophe De Champs, and Patrice Nordmann

A nosocomial outbreak of Pseudomonas aeruginosa isolates expressing the extended-spectrum ß-lactamase GES-2 in South Africa
J. Antimicrob. Chemother. 2002 49: 561-565; doi:10.1093/jac/49.3.561 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

D. Jonkers, J. Swennen, N. London, C. Driessen, and E. Stobberingh

Influence of cefazolin prophylaxis and hospitalization on the prevalence of antibiotic-resistant bacteria in the faecal flora
J. Antimicrob. Chemother. 2002 49: 567-571; doi:10.1093/jac/49.3.567 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

Kayode K. Ojo, Diana E. Waturangi, H. Akin Odelola, Antonius Suwanto, and Stefan Schwarz

Identification of a cassette-borne dfrA7-like gene that shows a 97 bp extension at the 3'-end of the reading frame
J. Antimicrob. Chemother. 2002 49: 573-574; doi:10.1093/jac/49.3.573 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Mignon du Plessis, Thora P. Capper, and Keith P. Klugman

In vitro activity of faropenem against respiratory pathogens
J. Antimicrob. Chemother. 2002 49: 575-577; doi:10.1093/jac/49.3.575 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

K. E. Bowker, M. Wootton, H. A. Holt, and A. P. MacGowan

In vitro activity of linezolid against Gram-positive isolates causing infection in continuous ambulatory peritoneal dialysis patients
J. Antimicrob. Chemother. 2002 49: 578-580; doi:10.1093/jac/49.3.578 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Franz-Josef Schmitz, Jasmina Petridou, Dana Milatovic, Jan Verhoef, Ad C. Fluit, and Stefan Schwarz

In vitro activity of new ketolides against macrolide-susceptible and -resistant Staphylococcus aureus isolates with defined resistance gene status
J. Antimicrob. Chemother. 2002 49: 580-582; doi:10.1093/jac/49.3.580 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Milan Cizman, Marko Pokorn, Metka Paragi, and the Slovenian Meningitis Study Group

Antimicrobial resistance of invasive Streptococcus pneumoniae in Slovenia from 1997 to 2000
J. Antimicrob. Chemother. 2002 49: 582-584; doi:10.1093/jac/49.3.582 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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