Journal of Antimicrobial Chemotherapy

Editorial:

David S. Reeves

Antimicrobial resistance surveillance: current initiatives are not enough
J. Antimicrob. Chemother. 2002 49: 1; doi:10.1093/jac/49.1.1 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Leading articles:

Deirdre Lewis

Antimicrobial resistance surveillance: methods will depend on objectives
J. Antimicrob. Chemother. 2002 49: 3-5; doi:10.1093/jac/49.1.3 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

A. K. Morris and R. G. Masterton

Antibiotic resistance surveillance: action for international studies
J. Antimicrob. Chemother. 2002 49: 7-10; doi:10.1093/jac/49.1.7 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

A. P. Fraise

Biocide abuse and antimicrobial resistance—a cause for concern?
J. Antimicrob. Chemother. 2002 49: 11-12; doi:10.1093/jac/49.1.11 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

B. Chattopadhyay

Newborns and gentamicin—how much and how often?
J. Antimicrob. Chemother. 2002 49: 13-16; doi:10.1093/jac/49.1.13 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Meeting report:

Pamela A. Hunter and David S. Reeves

The current status of surveillance of resistance to antimicrobial agents: report on a meeting
J. Antimicrob. Chemother. 2002 49: 17-23; doi:10.1093/jac/49.1.17 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

The 2000 Garrod Lecture:

Stuart B. Levy

Factors impacting on the problem of antibiotic resistance
J. Antimicrob. Chemother. 2002 49: 25-30; doi:10.1093/jac/49.1.25 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Review:

P. Ball, F. Baquero, O. Cars, T. File, J. Garau, K. Klugman, D. E. Low, E. Rubinstein, R. Wise, and The Consensus Group on Resistance and Prescribing in Respiratory Tract Infection

Antibiotic therapy of community respiratory tract infections: strategies for optimal outcomes and minimized resistance emergence
J. Antimicrob. Chemother. 2002 49: 31-40; doi:10.1093/jac/49.1.31 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Frank Notka, Hans-Jörg Linde, Arnd Dankesreiter, Hans-Helmut Niller, and Norbert Lehn

A C-terminal 18 amino acid deletion in MarR in a clinical isolate of Escherichia coli reduces MarR binding properties and increases the MIC of ciprofloxacin
J. Antimicrob. Chemother. 2002 49: 41-47; doi:10.1093/jac/49.1.41 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Benoît Doublet, Stefan Schwarz, Erika Nußbeck, Sylvie Baucheron, Jean-Louis Martel, Elisabeth Chaslus-Dancla, and Axel Cloeckaert

Molecular analysis of chromosomally florfenicol-resistant Escherichia coli isolates from France and Germany
J. Antimicrob. Chemother. 2002 49: 49-54; doi:10.1093/jac/49.1.49 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Juan P. Horcajada, Jordi Vila, Antonio Moreno-Martínez, Joaquim Ruiz, Jose Antonio Martínez, Miquel Sánchez, Eladio Soriano, and Josep Mensa

Molecular epidemiology and evolution of resistance to quinolones in Escherichia coli after prolonged administration of ciprofloxacin in patients with prostatitis
J. Antimicrob. Chemother. 2002 49: 55-59; doi:10.1093/jac/49.1.55 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ralf René Reinert, Adnan Al-Lahham, Maria Lemperle, Christoph Tenholte, Claudia Briefs, Stefan Haupts, Hans Hubert Gerards, and Rudolf Lütticken

Emergence of macrolide and penicillin resistance among invasive pneumococcal isolates in Germany
J. Antimicrob. Chemother. 2002 49: 61-68; doi:10.1093/jac/49.1.61 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Shio-Shin Jean, Lee-Jene Teng, Po-Ren Hsueh, Shen-Wu Ho, and Kwen-Tay Luh

Antimicrobial susceptibilities among clinical isolates of extended-spectrum cephalosporin-resistant Gram-negative bacteria in a Taiwanese University Hospital
J. Antimicrob. Chemother. 2002 49: 69-76; doi:10.1093/jac/49.1.69 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Constança Féria, Eugénia Ferreira, José Duarte Correia, José Gonçalves, and Manuela Caniça

Patterns and mechanisms of resistance to ß-lactams and ß-lactamase inhibitors in uropathogenic Escherichia coli isolated from dogs in Portugal
J. Antimicrob. Chemother. 2002 49: 77-85; doi:10.1093/jac/49.1.77 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Josephine J. Braid and Martin C. J. Wale

The antibacterial activity of triclosan-impregnated storage boxes against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Bacillus cereus and Shewanella putrefaciens in conditions simulating domestic use
J. Antimicrob. Chemother. 2002 49: 87-94; doi:10.1093/jac/49.1.87 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Eui-Il Hwang, Byoung-Mog Kwon, Seoung-Ho Lee, Na-Rae Kim, Tae-Hoon Kang, Young-Tae Kim, Byoung-Keun Park, and Sung-Uk Kim

Obovatols, new chitin synthase 2 inhibitors of Saccharomyces cerevisiae from Magnolia obovata
J. Antimicrob. Chemother. 2002 49: 95-101; doi:10.1093/jac/49.1.95 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

I. Sullayman Adagu, Deborah Nolder, David C. Warhurst, and Jean-François Rossignol

In vitro activity of nitazoxanide and related compounds against isolates of Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis
J. Antimicrob. Chemother. 2002 49: 103-111; doi:10.1093/jac/49.1.103 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Alexander A. Firsov, Stephen H. Zinner, Sergey N. Vostrov, Olga V. Kononenko, Yury A. Portnoy, Larissa V. Shustova, and Igor B. Kadenatsi

Comparative pharmacodynamics of azithromycin and roxithromycin with S. pyogenes and S. pneumoniae in a model that simulates in vitro pharmacokinetics in human tonsils
J. Antimicrob. Chemother. 2002 49: 113-119; doi:10.1093/jac/49.1.113 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

S. L. C. E. Buijk, I. C. Gyssens, J. W. Mouton, A. Van Vliet, H. A. Verbrugh, and H. A. Bruining

Pharmacokinetics of ceftazidime in serum and peritoneal exudate during continuous versus intermittent administration to patients with severe intra-abdominal infections
J. Antimicrob. Chemother. 2002 49: 121-128; doi:10.1093/jac/49.1.121 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Friederike Traunmüller, Peter Schenk, Christoph Mittermeyer, Renate Thalhammer-Scherrer, Klaus Ratheiser, and Florian Thalhammer

Clearance of ceftazidime during continuous venovenous haemofiltration in critically ill patients
J. Antimicrob. Chemother. 2002 49: 129-134; doi:10.1093/jac/49.1.129 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. Scanvic-Hameg, E. Chachaty, J. Rey, C. Pousson, M. L. Ozoux, E. Brunel, and A. Andremont

Impact of quinupristin/dalfopristin (RP59500) on the faecal microflora in healthy volunteers
J. Antimicrob. Chemother. 2002 49: 135-139; doi:10.1093/jac/49.1.135 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Eva Westman and Åsa Melhus

The treatment of Haemophilus influenzae acute otitis media with amoxicillin protects against reinfection but not against structural changes
J. Antimicrob. Chemother. 2002 49: 141-147; doi:10.1093/jac/49.1.141 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Antimicrobial practice:

Dilip Nathwani and Alan Tice

Ambulatory antimicrobial use: the value of an outcomes registry
J. Antimicrob. Chemother. 2002 49: 149-154; doi:10.1093/jac/49.1.149 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Eytan Cohen, Alexander Dadashev, Moshe Drucker, Zmira Samra, Ethan Rubinstein, and Moshe Garty

Once–daily versus twice–daily intravenous administration of vancomycin for infections in hospitalized patients
J. Antimicrob. Chemother. 2002 49: 155-160; doi:10.1093/jac/49.1.155 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Philip A. Chambers, Paula S. Duggan, John Heritage, and J. Michael Forbes

The fate of antibiotic resistance marker genes in transgenic plant feed material fed to chickens
J. Antimicrob. Chemother. 2002 49: 161-164; doi:10.1093/jac/49.1.161 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jeremy I. Ross, E. Anne Eady, Ellen Carnegie, and Jonathan H. Cove

Detection of transposon Tn5432–mediated macrolide-lincosamide-streptogramin B (MLS_B) resistance in cutaneous propionibacteria from six European cities
J. Antimicrob. Chemother. 2002 49: 165-168; doi:10.1093/jac/49.1.165 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Rajaa AitMhand, Abdelaziz Soukri, Najat Moustaoui, Hamid Amarouch, Naima ElMdaghri, Danielle Sirot, and Mohamed Benbachir

Plasmid-mediated TEM-3 extended-spectrum ß-lactamase production in Salmonella typhimurium in Casablanca
J. Antimicrob. Chemother. 2002 49: 169-172; doi:10.1093/jac/49.1.169 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Lesley McGee, Colin E. Goldsmith, and Keith P. Klugman

Fluoroquinolone resistance among clinical isolates of Streptococcus pneumoniae belonging to international multiresistant clones
J. Antimicrob. Chemother. 2002 49: 173-176; doi:10.1093/jac/49.1.173 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

T. M. A. Weller, J. M. Andrews, G. Jevons, and R. Wise

The in vitro activity of BMS-284756, a new des-fluorinated quinolone
J. Antimicrob. Chemother. 2002 49: 177-184; doi:10.1093/jac/49.1.177 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Elizabeth Gradelski, Benjamin Kolek, Daniel Bonner, and Joan Fung-Tomc

Bactericidal mechanism of gatifloxacin compared with other quinolones
J. Antimicrob. Chemother. 2002 49: 185-188; doi:10.1093/jac/49.1.185 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Christof von Eiff and Georg Peters

Comparative in vitro activity of ABT-773 and two macrolides against staphylococci
J. Antimicrob. Chemother. 2002 49: 189-192; doi:10.1093/jac/49.1.189 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Andrea Giacometti, Oscar Cirioni, Roberto Ghiselli, Federico Mocchegiani, Alessandra Mataloni Paggi, Fiorenza Orlando, Wojciech Kamysz, Franciszek Kasprzykowski, Zbigniew Mackiewicz, Giorgio Scalise, and Vittorio Saba

Therapeutic efficacy of intraperitoneal polymyxin B and polymyxin-like peptides alone or combined with levofloxacin in rat models of septic shock
J. Antimicrob. Chemother. 2002 49: 193-196; doi:10.1093/jac/49.1.193 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Tor Monsen, Hadi Abd, Kjell Leonardsson, Helén Edebro, and Johan Wiström

Prediction of mecA-positive coagulase-negative staphylococci: assessment of different phenotypic methods, breakpoints, culture media and culture conditions
J. Antimicrob. Chemother. 2002 49: 197-200; doi:10.1093/jac/49.1.197 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

K. P. Shannon and G. L. French

Antibiotic resistance: effect of different criteria for classifying isolates as duplicates on apparent resistance frequencies
J. Antimicrob. Chemother. 2002 49: 201-204; doi:10.1093/jac/49.1.201 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

C. Agustí, M. Pujol, M. J. Argerich, J. Ayats, M. Badía, M. A. Domínguez, X. Corbella, and J. Ariza

Short-term effect of the application of selective decontamination of the digestive tract on different body site reservoir ICU patients colonized by multi-resistant Acinetobacter baumannii
J. Antimicrob. Chemother. 2002 49: 205-208; doi:10.1093/jac/49.1.205 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Mahomed-Yunus S. Moosa, George J. Alangaden, Elias Manavathu, and Pranatharthi H. Chandrasekar

Resistance to amphotericin B does not emerge during treatment for invasive aspergillosis
J. Antimicrob. Chemother. 2002 49: 209-213; doi:10.1093/jac/49.1.209 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

Laura J. V. Piddock

J. Antimicrob. Chemother. 2002 49: 215; doi:10.1093/jac/49.1.215 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

C. Novais, C. Vital, G. Ribeiro, T. M. Coque, and L. V. Peixe

First characterization of vancomycin-resistant enterococci from a Portuguese hospital
J. Antimicrob. Chemother. 2002 49: 215-217; doi:10.1093/jac/49.1.215-a [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Luke Tysall, Mark W. Stockdale, Paul R. Chadwick, Marie-France I. Palepou, Kevin J. Towner, David M. Livermore, and Neil Woodford

IMP-1 carbapenemase detected in an Acinetobacter clinical isolate from the UK
J. Antimicrob. Chemother. 2002 49: 217-218; doi:10.1093/jac/49.1.217 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

R. G. Masterton

Ciprofloxacin resistance—‘early-warning’ signs from the MYSTIC surveillance programme?
J. Antimicrob. Chemother. 2002 49: 218-220; doi:10.1093/jac/49.1.218 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

F.-J. Schmitz, M. Boos, S. Mayer, J. Verhoef, D. Milatovic, and A. C. Fluit

In vitro activity of faropenem and 20 other compounds against ß-lactamase-positive and -negative Moraxella catarrhalis and Haemophilus influenzae isolates and the effect of serum on faropenem MICs
J. Antimicrob. Chemother. 2002 49: 220-223; doi:10.1093/jac/49.1.220 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

B. I. F. Batchelor, D. W. M. Crook, T. Jones, and I. C. J. W. Bowler

Impact of guidelines for the diagnosis of urinary tract infection on trimethoprim susceptibility of Escherichia coli
J. Antimicrob. Chemother. 2002 49: 223-224; doi:10.1093/jac/49.1.223 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Book reviews:

James Bingham

Fast Facts—Sexually Transmitted Infections: A. Edwards, J. Sherrard and J. Zenilman. Health Press, Oxford, UK, 2001. ISBN 1-899541-04-7.
J. Antimicrob. Chemother. 2002 49: 225; doi:10.1093/jac/49.1.225 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

T. Treasure

Handbook of Infections in Surgery: R. C. Kester, Ed. Science Press, London, UK, 2000. ISBN 1-85973-383-9.
J. Antimicrob. Chemother. 2002 49: 225-226; doi:10.1093/jac/49.1.225-a [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Stephen H. Gillespie

Mycobacterium tuberculosis Protocols. Methods in Molecular Medicine series.: T. Parish and N. G. Stoker, Eds. Humana Press, Totowa, NJ, USA. ISBN 0-89603-776-2. 403 pp.
J. Antimicrob. Chemother. 2002 49: 226; doi:10.1093/jac/49.1.226 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Erratum:

Stephen Taylor, David J. Back, Susan M. Drake, Judith Workman, Helen Reynolds, Sara E. Gibbons, David J. White, and Deenan Pillay

Antiretroviral drug concentrations in semen of HIV-infected men: differential penetration of indinavir, ritonavir and saquinavir
J. Antimicrob. Chemother. 2002 49: 227; doi:10.1093/jac/49.1.227 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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