Journal of Antimicrobial Chemotherapy

Review:

Andrew Berrington and F. Kate Gould

Use of antibiotic locks to treat colonized central venous catheters
J. Antimicrob. Chemother. 2001 48: 597-603; doi:10.1093/jac/48.5.597 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

C. M. Tobin, J. Sunderland, L. O. White, and A. P. MacGowan

A simple, isocratic high-performance liquid chromatography assay for linezolid in human serum
J. Antimicrob. Chemother. 2001 48: 605-608; doi:10.1093/jac/48.5.605 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Robert J. Fass and Jean Barnishan

Comparison of antimicrobial in vitro activities against Streptococcus pneumoniae independent of MIC susceptibility breakpoints using MIC frequency distribution curves, scattergrams and linear regression analyses
J. Antimicrob. Chemother. 2001 48: 609-615; doi:10.1093/jac/48.5.609 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Susan Boyle-Vavra, Roberta B. Carey, and Robert S. Daum

Development of vancomycin and lysostaphin resistance in a methicillin-resistant Staphylococcus aureus isolate
J. Antimicrob. Chemother. 2001 48: 617-625; doi:10.1093/jac/48.5.617 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. Mavroidi, E. Tzelepi, A. Tsakris, V. Miriagou, D. Sofianou, and L. S. Tzouvelekis

An integron-associated ß-lactamase (IBC-2) from Pseudomonas aeruginosa is a variant of the extended-spectrum ß-lactamase IBC-1
J. Antimicrob. Chemother. 2001 48: 627-630; doi:10.1093/jac/48.5.627 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Corinna Kehrenberg, Sarah A. Salmon, Jeffrey L. Watts, and Stefan Schwarz

Tetracycline resistance genes in isolates of Pasteurella multocida, Mannheimia haemolytica, Mannheimia glucosida and Mannheimia varigena from bovine and swine respiratory disease: intergeneric spread of the tet(H) plasmid pMHT1
J. Antimicrob. Chemother. 2001 48: 631-640; doi:10.1093/jac/48.5.631 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ellie J. C. Goldstein, Diane M. Citron, C. Vreni Merriam, Yumi A. Warren, Kerin Tyrrell, and Helen Fernandez

Comparative in vitro activity of ertapenem and 11 other antimicrobial agents against aerobic and anaerobic pathogens isolated from skin and soft tissue animal and human bite wound infections
J. Antimicrob. Chemother. 2001 48: 641-651; doi:10.1093/jac/48.5.641 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Robert Skov, Jens Jørgen Christensen, Bent Korner, Niels Frimodt-Møller, and Frank Espersen

In vitro antimicrobial susceptibility of Aerococcus urinae to 14 antibiotics, and time–kill curves for penicillin, gentamicin and vancomycin
J. Antimicrob. Chemother. 2001 48: 653-658; doi:10.1093/jac/48.5.653 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

P. L. Ho, R. W. H. Yung, D. N. C. Tsang, T. L. Que, M. Ho, W. H. Seto, T. K. Ng, W. C. Yam, and Wilson W. S. Ng

Increasing resistance of Streptococcus pneumoniae to fluoroquinolones: results of a Hong Kong multicentre study in 2000
J. Antimicrob. Chemother. 2001 48: 659-665; doi:10.1093/jac/48.5.659 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Paul H. Edelstein, Takashi Shinzato, and Martha A. C. Edelstein

BMS-284756 (T-3811ME) a new fluoroquinolone: in vitro activity against Legionella, efficacy in a guinea pig model of L. pneumophila pneumonia and pharmacokinetics in guinea pigs
J. Antimicrob. Chemother. 2001 48: 667-675; doi:10.1093/jac/48.5.667 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

John P.A. Ioannidis, Despina G. Contopoulos-Ioannidis, Priscilla Chew, and Joseph Lau

Meta-analysis of randomized controlled trials on the comparative efficacy and safety of azithromycin against other antibiotics for upper respiratory tract infections
J. Antimicrob. Chemother. 2001 48: 677-689; doi:10.1093/jac/48.5.677 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Despina G. Contopoulos-Ioannidis, John P. A. Ioannidis, Priscilla Chew, and Joseph Lau

Meta-analysis of randomized controlled trials on the comparative efficacy and safety of azithromycin against other antibiotics for lower respiratory tract infections
J. Antimicrob. Chemother. 2001 48: 691-703; doi:10.1093/jac/48.5.691 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

E. Banfi, M. G. Mamolo, D. Zampieri, L. Vio, and C. Monti Bragadin

Antimycobacterial activity of N1-{1-[3-aryl-1-(pyridin-2-, 3- or 4-yl)-3-oxo] propyl}-2-pyridinecarboxamidrazones
J. Antimicrob. Chemother. 2001 48: 705-707; doi:10.1093/jac/48.5.705 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

F. Alovero, A. Barnes, M. Nieto, M. R. Mazzieri, and R. H. Manzo

Comparative study of new benzenesulphonamide fluoroquinolones structurally related to ciprofloxacin against selected ciprofloxacin-susceptible and -resistant Gram-positive cocci
J. Antimicrob. Chemother. 2001 48: 709-712; doi:10.1093/jac/48.5.709 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

F.-M. C. Müller, O. Kurzai, J. Hacker, M. Frosch, and F. Mühlschlegel

Effect of the growth medium on the in vitro antifungal activity of micafungin (FK-463) against clinical isolates of Candida dubliniensis
J. Antimicrob. Chemother. 2001 48: 713-715; doi:10.1093/jac/48.5.713 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Daniel Aubert, Laurent Poirel, Adel Ben Ali, Fred W. Goldstein, and Patrice Nordmann

OXA-35 is an OXA-10-related ß-lactamase from Pseudomonas aeruginosa
J. Antimicrob. Chemother. 2001 48: 717-721; doi:10.1093/jac/48.5.717 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Shuichi Miyazaki, Toshihiko Fujikawa, Katsumori Kanazawa, and Keizo Yamaguchi

In vitro and in vivo activities of meropenem and comparable antimicrobial agents against Haemophilus influenzae, including ß-lactamase-negative ampicillin-resistant strains
J. Antimicrob. Chemother. 2001 48: 723-726; doi:10.1093/jac/48.5.723 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jonathan Turner, Robin A. Howe, Mandy Wootton, Karen E. Bowker, H. Alan Holt, Vyvyan Salisbury, Peter M. Bennett, Timothy R. Walsh, and Alasdair P. MacGowan

The activity of vancomycin against heterogeneous vancomycin-intermediate methicillin-resistant Staphylococcus aureus explored using an in vitro pharmacokinetic model
J. Antimicrob. Chemother. 2001 48: 727-730; doi:10.1093/jac/48.5.727 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Katalin Glatz, Dóra Szabó, György Szabó, Dimitrinka Boriszova, and Ferenc Rozgonyi

Emergence of extremely high penicillin and cefotaxime resistance and high-level levofloxacin resistance in clinical isolates of Streptococcus pneumoniae in Hungary
J. Antimicrob. Chemother. 2001 48: 731-734; doi:10.1093/jac/48.5.731 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

Margaret R. Hammerschlag

Efficacy and safety of gemifloxacin in the treatment of community-acquired pneumonia: a randomized, double-blind comparison with trovafloxacin
J. Antimicrob. Chemother. 2001 48: 735; doi:10.1093/jac/48.5.735 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Joan Fung-Tomc, Lourdes Valera, Beatrice Minassian, Daniel Bonner, and Elizabeth Gradelski

Activity of the novel des-fluoro(6) quinolone BMS-284756 against methicillin-susceptible and -resistant staphylococci
J. Antimicrob. Chemother. 2001 48: 735-738; doi:10.1093/jac/48.5.735-a [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Christine Lascols, André Bryskier, Claude-James Soussy, and Jacques Tankovic

Effect of pH on the susceptibility of Helicobacter pylori to the ketolide telithromycin (HMR 3647) and clarithromycin
J. Antimicrob. Chemother. 2001 48: 738-740; doi:10.1093/jac/48.5.738 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

E. John Threlfall, Jeremy A. Skinner, and Linda R. Ward

Detection of decreased in vitro susceptibility to ciprofloxacin in Salmonella enterica serotypes Typhi and Paratyphi A
J. Antimicrob. Chemother. 2001 48: 740-741; doi:10.1093/jac/48.5.740 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Jon S. Brazier, Warren Fawley, Jane Freeman, and Mark H. Wilcox

Reduced susceptibility of Clostridium difficile to metronidazole
J. Antimicrob. Chemother. 2001 48: 741-742; doi:10.1093/jac/48.5.741 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Takashi Deguchi, Shin-Ichi Maeda, Masayoshi Tamaki, Takashi Yoshida, Hiroaki Ishiko, Masayasu Ito, Shigeaki Yokoi, Yoshihito Takahashi, and Satoshi Ishihara

Analysis of the gyrA and parC genes of Mycoplasma genitalium detected in first-pass urine of men with non-gonococcal urethritis before and after fluoroquinolone treatment
J. Antimicrob. Chemother. 2001 48: 742-744; doi:10.1093/jac/48.5.742 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Katherine J. Gray, Deborah M. Gascoyne-Binzi, Philippa Nicholson, John Heritage, and Peter M. Hawkey

Transmissible fosfomycin resistance markers in urinary isolates and imported foodstuffs in the UK during 1994 and 1995
J. Antimicrob. Chemother. 2001 48: 744-745; doi:10.1093/jac/48.5.744 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

R. del Campo, C. Tenorio, M. Zarazaga, R. Gomez-Lus, F. Baquero, and C. Torres

Detection of a single vanA-containing Enterococcus faecalis clone in hospitals in different regions in Spain
J. Antimicrob. Chemother. 2001 48: 746-747; doi:10.1093/jac/48.5.746 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Andrea Guyot and Steve P. Barrett

What is an appropriate control group to identify risk factors for Clostridium difficile-associated diarrhoea?
J. Antimicrob. Chemother. 2001 48: 747-748; doi:10.1093/jac/48.5.747 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Book review:

N. Shetty

Clinician's Manual on Antibiotic Prescribing in the Community: E. Brown. Science Press, London, UK, 2000. ISBN 1-85873-916-0. 74 pp.
J. Antimicrob. Chemother. 2001 48: 749; doi:10.1093/jac/48.5.749 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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