Journal of Antimicrobial Chemotherapy

Original articles:

Bisoen Rambali, Juan Antonio Fernandez, Luc Van Nuffel, Filip Woestenborghs, Lieven Baert, Desire L. Massart, and Frank C. Odds

Susceptibility testing of pathogenic fungi with itraconazole: a process analysis of test variables
J. Antimicrob. Chemother. 2001 48: 163-177; doi:10.1093/jac/48.2.163 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

B. Pradines, T. Fusai, W. Daries, V. Laloge, C. Rogier, P. Millet, E. Panconi, M. Kombila, and D. Parzy

Ferrocene-chloroquine analogues as antimalarial agents: in vitro activity of ferrochloroquine against 103 Gabonese isolates of Plasmodium falciparum
J. Antimicrob. Chemother. 2001 48: 179-184; doi:10.1093/jac/48.2.179 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Patricia Minkowski, Hannah Staege, Peter Groscurth, and Andreas Schaffner

Effects of trimethoprim and co-trimoxazole on the morphology of Listeria monocytogenes in culture medium and after phagocytosis
J. Antimicrob. Chemother. 2001 48: 185-193; doi:10.1093/jac/48.2.185 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Laura E. Lawrence, Ping Wu, Li Fan, Kristine E. Gouveia, Amy Card, Margaret Casperson, Kenneth Denbleyker, and John F. Barrett

The inhibition and selectivity of bacterial topoisomerases by BMS-284756 and its analogues
J. Antimicrob. Chemother. 2001 48: 195-201; doi:10.1093/jac/48.2.195 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Hilde Ulvatne, Silje Karoliussen, Trine Stiberg, Øystein Rekdal, and John S. Svendsen

Short antibacterial peptides and erythromycin act synergically against Escherichia coli
J. Antimicrob. Chemother. 2001 48: 203-208; doi:10.1093/jac/48.2.203 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Katharina Grif, Manfred P. Dierich, Kristian Pfaller, Pier A. Miglioli, and Franz Allerberger

In vitro activity of fosfomycin in combination with various antistaphylococcal substances
J. Antimicrob. Chemother. 2001 48: 209-217; doi:10.1093/jac/48.2.209 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Anna King and Ian Phillips

The in vitro activity of daptomycin against 514 Gram-positive aerobic clinical isolates
J. Antimicrob. Chemother. 2001 48: 219-223; doi:10.1093/jac/48.2.219 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Emilio Pérez-Trallero, Diego Vicente, Milagrosa Montes, José M. Marimon, and Luis Piñeiro

High proportion of pharyngeal carriers of commensal streptococci resistant to erythromycin in Spanish adults
J. Antimicrob. Chemother. 2001 48: 225-229; doi:10.1093/jac/48.2.225 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. Polyzou, A. Slavakis, S. Pournaras, A. N. Maniatis, D. Sofianou, and A. Tsakris

Predominance of a methicillin-resistant Staphylococcus aureus clone susceptible to erythromycin and several other non-ß-lactam antibiotics in a Greek hospital
J. Antimicrob. Chemother. 2001 48: 231-234; doi:10.1093/jac/48.2.231 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Marleen Van Looveren, Georges Daube, Lieven De Zutter, Jean-Marie Dumont, Christine Lammens, Monik Wijdooghe, Peter Vandamme, Martine Jouret, Marc Cornelis, and Herman Goossens

Antimicrobial susceptibilities of Campylobacter strains isolated from food animals in Belgium
J. Antimicrob. Chemother. 2001 48: 235-240; doi:10.1093/jac/48.2.235 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Doron Steinberg, Meir Moldovan, and David Molukandov

Testing a degradable topical varnish of cetylpyridinium chloride in an experimental dental biofilm model
J. Antimicrob. Chemother. 2001 48: 241-243; doi:10.1093/jac/48.2.241 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Yona Shadkchan and Esther Segal

Treatment of experimental candidosis with amphotericin B–Intralipid admixtures in immunocompromised mice
J. Antimicrob. Chemother. 2001 48: 245-251; doi:10.1093/jac/48.2.245 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Mark E. Shirtliff, Jason H. Calhoun, and Jon T. Mader

Comparative evaluation of oral levofloxacin and parenteral nafcillin in the treatment of experimental methicillin-susceptible Staphylococcus aureus osteomyelitis in rabbits
J. Antimicrob. Chemother. 2001 48: 253-258; doi:10.1093/jac/48.2.253 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Myo-Kyoung Kim, Dawei Xuan, Richard Quintiliani, Charles H. Nightingale, and David P. Nicolau

Pharmacokinetic and pharmacodynamic profile of high dose extended interval piperacillin–tazobactam
J. Antimicrob. Chemother. 2001 48: 259-267; doi:10.1093/jac/48.2.259 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Itzhak Brook and Kiran Shah

Effect of amoxycillin with or without clavulanate on adenoid bacterial flora
J. Antimicrob. Chemother. 2001 48: 269-273; doi:10.1093/jac/48.2.269 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Marc J. Schultz, Peter Speelman, and Tom van der Poll

Erythromycin inhibits Pseudomonas aeruginosa-induced tumour necrosis factor- production in human whole blood
J. Antimicrob. Chemother. 2001 48: 275-278; doi:10.1093/jac/48.2.275 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ralf René Reinert, Adnan Al-Lahham, and Rudolf Lütticken

In vitro activity of cefditoren against clinical isolates of penicillin-susceptible and penicillin-intermediate strains of Streptococcus pneumoniae isolated in Germany, 1992–1998
J. Antimicrob. Chemother. 2001 48: 279-281; doi:10.1093/jac/48.2.279 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

S. Noviello, F. Ianniello, and S. Esposito

In vitro activity of LY333328 (oritavancin) against Gram-positive aerobic cocci and synergy with ciprofloxacin against enterococci
J. Antimicrob. Chemother. 2001 48: 283-286; doi:10.1093/jac/48.2.283 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

John Heritage, Nicola Ransome, Philip A. Chambers, and Mark H. Wilcox

A comparison of culture and PCR to determine the prevalence of ampicillin-resistant bacteria in the faecal flora of general practice patients
J. Antimicrob. Chemother. 2001 48: 287-289; doi:10.1093/jac/48.2.287 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

P. Weber, J. Filipecki, E. Bingen, F. Fitoussi, G. Goldfarb, J. P. Chauvin, C. Reitz, and H. Portier

Genetic and phenotypic characterization of macrolide resistance in group A streptococci isolated from adults with pharyngo-tonsillitis in France
J. Antimicrob. Chemother. 2001 48: 291-294; doi:10.1093/jac/48.2.291 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Manuel López-Brea, Maria Josefa Martínez, Diego Domingo, and Teresa Alarcón

A 9 year study of clarithromycin and metronidazole resistance in Helicobacter pylori from Spanish children
J. Antimicrob. Chemother. 2001 48: 295-297; doi:10.1093/jac/48.2.295 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Roberto Manfredi, Leonardo Calza, and Francesco Chiodo

Dual nucleoside analogue treatment in the era of highly active antiretroviral therapy (HAART): a single-centre cross-sectional survey
J. Antimicrob. Chemother. 2001 48: 299-302; doi:10.1093/jac/48.2.299 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Antimicrobial practice:

S. Natsch, M. H. M. Steeghs, Y. A. Hekster, J. F. G. M. Meis, J. W. M. van der Meer, and B. J. Kullberg

Use of fluconazole in daily practice: still room for improvement
J. Antimicrob. Chemother. 2001 48: 303-310; doi:10.1093/jac/48.2.303 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Benjamin P. Howden and Michael J. Richards

The efficacy of continuous infusion flucloxacillin in home therapy for serious staphylococcal infections and cellulitis
J. Antimicrob. Chemother. 2001 48: 311-314; doi:10.1093/jac/48.2.311 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

Dragana Drinkovic, Elizabeth R. Fuller, Keith P. Shore, David J. Holland, and Rod Ellis-Pegler

Clindamycin treatment of Staphylococcus aureus expressing inducible clindamycin resistance
J. Antimicrob. Chemother. 2001 48: 315-316; doi:10.1093/jac/48.2.315 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Po-Ren Hsueh, Lee-Jene Teng, Tsu-Lan Wu, Shen-Wu Ho, and Kwen-Tay Luh

First clinical isolate of Streptococcus pneumoniae exhibiting high-level resistance to fluoroquinolones in Taiwan
J. Antimicrob. Chemother. 2001 48: 316-317; doi:10.1093/jac/48.2.316 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Karen M. Rudolph, Alan J. Parkinson, and Marilyn C. Roberts

Mechanisms of erythromycin and trimethoprim resistance in the Alaskan Streptococcus pneumoniae serotype 6B clone
J. Antimicrob. Chemother. 2001 48: 317-319; doi:10.1093/jac/48.2.317 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

John E. Moore, Mary Crowe, Adrienne Shaw, John McCaughan, Aileen O. B. Redmond, and J. Stuart Elborn

Antibiotic resistance in Burkholderia cepacia at two regional cystic fibrosis centres in Northern Ireland: is there a need for synergy testing?
J. Antimicrob. Chemother. 2001 48: 319-321; doi:10.1093/jac/48.2.319 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Lukasz Naumiuk, Alfred Samet, and Elzbieta Dziemaszkiewicz

Cefepime in vitro activity against derepressed extended-spectrum ß-lactamase (ESBL)-producing and non-ESBL-producing Enterobacter cloacae by a disc diffusion method
J. Antimicrob. Chemother. 2001 48: 321-322; doi:10.1093/jac/48.2.321 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

J. M. Andrews and R. Wise

In vitro susceptibility testing of BMS-284756 by the BSAC standardized disc testing method
J. Antimicrob. Chemother. 2001 48: 322-324; doi:10.1093/jac/48.2.322 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Gary Cotter and Catherine C. Adley

Ciprofloxacin susceptibility testing of enterococcal urinary isolates in accordance with BSAC guidelines
J. Antimicrob. Chemother. 2001 48: 324-325; doi:10.1093/jac/48.2.324 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Baudouin Byl, Daniel Baran, Frédérique Jacobs, André Herschuelz, and Jean-Pierre Thys

Serum pharmacokinetics and sputum penetration of amikacin 30 mg/kg once daily and of ceftazidime 200 mg/kg/day as a continuous infusion in cystic fibrosis patients
J. Antimicrob. Chemother. 2001 48: 325-327; doi:10.1093/jac/48.2.325 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Roberto Reckziegel, Ismael Maguilnik, and Luciano Z. Goldani

Gentamicin concentration in bile after once-daily versus thrice-daily dosing of 4 mg/kg/day
J. Antimicrob. Chemother. 2001 48: 327-329; doi:10.1093/jac/48.2.327 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Book review:

Rosemary A. Barnes

Medical Microbiology and Infection at a Glance: S. Gillespie and K. Bamford.Blackwell Science Ltd, Oxford, 2000.ISBN 0-632-05026-8. £12.95 pp. 120.
J. Antimicrob. Chemother. 2001 48: 331; doi:10.1093/jac/48.2.331 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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