Journal of Antimicrobial Chemotherapy

Original articles:

Courtney Slater-Radosti, Glenn Van Aller, Rebecca Greenwood, Richard Nicholas, Paul M. Keller, Walter E. DeWolf, Jr, Frank Fan, David J. Payne, and Deborah D. Jaworski

Biochemical and genetic characterization of the action of triclosan on Staphylococcus aureus
J. Antimicrob. Chemother. 2001 48: 1-6; doi:10.1093/jac/48.1.1 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Bart Gottenbos, Dirk W. Grijpma, Henny C. van der Mei, Jan Feijen, and Henk J. Busscher

Antimicrobial effects of positively charged surfaces on adhering Gram-positive and Gram-negative bacteria
J. Antimicrob. Chemother. 2001 48: 7-13; doi:10.1093/jac/48.1.7 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Christine E. Thorburn and David I. Edwards

The effect of pharmacokinetics on the bactericidal activity of ciprofloxacin and sparfloxacin against Streptococcus pneumoniae and the emergence of resistance
J. Antimicrob. Chemother. 2001 48: 15-22; doi:10.1093/jac/48.1.15 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Peter C. Fuchs, Arthur L. Barry, and Steven D. Brown

Comparative in vitro antimicrobial activity of a new carbapenem, E1010, and tentative disc diffusion test interpretative criteria
J. Antimicrob. Chemother. 2001 48: 23-28; doi:10.1093/jac/48.1.23 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Siddhartha Roychoudhury, Tracy L. Twinem, Kelly M. Makin, Eric J. McIntosh, Benoit Ledoussal, and Carl E. Catrenich

Activity of non-fluorinated quinolones (NFQs) against quinolone-resistant Escherichia coli and Streptococcus pneumoniae
J. Antimicrob. Chemother. 2001 48: 29-36; doi:10.1093/jac/48.1.29 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

L. Drago, E. De Vecchi, B. Mombelli, L. Nicola, M. Valli, and M. R. Gismondo

Activity of levofloxacin and ciprofloxacin against urinary pathogens
J. Antimicrob. Chemother. 2001 48: 37-45; doi:10.1093/jac/48.1.37 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Curtis G. Gemmell and on behalf of participating investigators in France, Germany, Holland, Spain, Italy, Sweden and the UK

Susceptibility of a variety of clinical isolates to linezolid: a European inter-country comparison
J. Antimicrob. Chemother. 2001 48: 47-52; doi:10.1093/jac/48.1.47 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Anita Hällgren, Hossein Abednazari, Christer Ekdahl, Håkan Hanberger, Maud Nilsson, Annika Samuelsson, Erik Svensson, Lennart E. Nilsson, and the Swedish ICU Study Group

Antimicrobial susceptibility patterns of enterococci in intensive care units in Sweden evaluated by different MIC breakpoint systems
J. Antimicrob. Chemother. 2001 48: 53-62; doi:10.1093/jac/48.1.53 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

D. Honeybourne, D. Banerjee, J. Andrews, and R. Wise

Concentrations of gatifloxacin in plasma and pulmonary compartments following a single 400 mg oral dose in patients undergoing fibre-optic bronchoscopy
J. Antimicrob. Chemother. 2001 48: 63-66; doi:10.1093/jac/48.1.63 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

T. M. File, Jr, B. Schlemmer, J. Garau, M. Cupo, C. Young, and the 049 Clinical Study Group

Efficacy and safety of gemifloxacin in the treatment of community-acquired pneumonia: a randomized, double-blind comparison with trovafloxacin
J. Antimicrob. Chemother. 2001 48: 67-74; doi:10.1093/jac/48.1.67 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Nir Osherov, Dimitrios P. Kontoyiannis, Angela Romans, and Gregory S. May

Resistance to itraconazole in Aspergillus nidulans and Aspergillus fumigatus is conferred by extra copies of the A. nidulans P-450 14-demethylase gene, pdmA
J. Antimicrob. Chemother. 2001 48: 75-81; doi:10.1093/jac/48.1.75 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Géraldine Piel, Marie Pierre Hayette, Ermanno Pavoni, Brigitte Evrard, Thierry Van Hees, Sandrine Henri de Hassonville, Patrick De Mol, and Luc Delattre

In vitro comparison of the antimycotic activity of a miconazole–HP-ß-cyclodextrin solution with a miconazole surfactant solution
J. Antimicrob. Chemother. 2001 48: 83-87; doi:10.1093/jac/48.1.83 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Elisabeth J. Ruijgrok, Arnold G. Vulto, and Els W. M. Van Etten

Efficacy of aerosolized amphotericin B desoxycholate and liposomal amphotericin B in the treatment of invasive pulmonary aspergillosis in severely immunocompromised rats
J. Antimicrob. Chemother. 2001 48: 89-95; doi:10.1093/jac/48.1.89 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Marc Boogaerts, Johan Maertens, Achiel van Hoof, Robrecht de Bock, Georges Fillet, Marc Peetermans, Dominik Selleslag, Bernard Vandercam, Koenraad Vandewoude, Pierre Zachée, and Karel De Beule

Itraconazole versus amphotericin B plus nystatin in the prophylaxis of fungal infections in neutropenic cancer patients
J. Antimicrob. Chemother. 2001 48: 97-103; doi:10.1093/jac/48.1.97 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Joseph S. Friedberg, Cynthia Skema, Eric D. Baum, Jeffrey Burdick, Sergei A. Vinogradov, David F. Wilson, Annamarie D. Horan, and Irving Nachamkin

In vitro effects of photodynamic therapy on Aspergillus fumigatus
J. Antimicrob. Chemother. 2001 48: 105-107; doi:10.1093/jac/48.1.105 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

David T. Bearden and Lance A. Muncey

The effect of amiloride on amphotericin B-induced hypokalaemia
J. Antimicrob. Chemother. 2001 48: 109-111; doi:10.1093/jac/48.1.109 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Carlo Torti, Anton Pozniak, Mark Nelson, Kurt Hertogs, and Brian G. Gazzard

Distribution of K103N and/or Y181C HIV-1 mutations by exposure to zidovudine and non-nucleoside reverse transcriptase inhibitors
J. Antimicrob. Chemother. 2001 48: 113-116; doi:10.1093/jac/48.1.113 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

T. A. Wichelhaus, E. Dingeldein, M. Rauschmann, S. Kluge, R. Dieterich, V. Schäfer, and V. Brade

Elution characteristics of vancomycin, teicoplanin, gentamicin and clindamycin from calcium sulphate beads
J. Antimicrob. Chemother. 2001 48: 117-119; doi:10.1093/jac/48.1.117 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Arthur L. Barry, Peter C. Fuchs, and Steven D. Brown

Interpretative criteria and quality control parameters for telithromycin disc diffusion susceptibility tests
J. Antimicrob. Chemother. 2001 48: 121-125; doi:10.1093/jac/48.1.121 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ruth Horn and Hugh G. Robson

Susceptibility of the Bacteroides fragilis group to newer quinolones and other standard anti-anaerobic agents
J. Antimicrob. Chemother. 2001 48: 127-130; doi:10.1093/jac/48.1.127 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Michele Guitton, Carole Delachaume, Pascal Le Priol, Valérie Steier, and Alain Bonnefoy

In vitro and in vivo efficacy of a novel fluoro-ketolide HMR 3562 against enterococci
J. Antimicrob. Chemother. 2001 48: 131-135; doi:10.1093/jac/48.1.131 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Satoshi Yoshizumi, Yoshie Takahashi, Mitsuo Murata, Haruki Domon, Nobuhiko Furuya, Yoshikazu Ishii, Tetsuya Matsumoto, Akira Ohno, Kazuhiro Tateda, Shuichi Miyazaki, and Keizo Yamaguchi

The in vivo activity of olamufloxacin (HSR-903) in systemic and urinary tract infections in mice
J. Antimicrob. Chemother. 2001 48: 137-140; doi:10.1093/jac/48.1.137 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

Michael R. W. Brown and Anthony W. Smith

Dormancy and persistence in chronic infection: role of the general stress response in resistance to chemotherapy
J. Antimicrob. Chemother. 2001 48: 141-142; doi:10.1093/jac/48.1.141 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Prashini Moodley, Jules Hoppenbrouwers, Louise Bohlken, and A. Willem Sturm

Emergence of TetM-mediated tetracycline resistance in rural South Africa
J. Antimicrob. Chemother. 2001 48: 142-143; doi:10.1093/jac/48.1.142 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Alan P. Johnson, Hazel M. Aucken, Susan Cavendish, Mark Ganner, Martin C. J. Wale, Marina Warner, David M. Livermore, Barry D. Cookson, and the UK EARSS participants

Dominance of EMRSA-15 and -16 among MRSA causing nosocomial bacteraemia in the UK: analysis of isolates from the European Antimicrobial Resistance Surveillance System (EARSS)
J. Antimicrob. Chemother. 2001 48: 143-144; doi:10.1093/jac/48.1.143 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Mark H. Wilcox and Warren Fawley

Extremely low prevalence of UK Staphylococcus aureus isolates with reduced susceptibility to vancomycin
J. Antimicrob. Chemother. 2001 48: 144-145; doi:10.1093/jac/48.1.144 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

J. I. Alós, J. Oteo, B. Aracil, and J. L. Gómez-Garcés

Comparative in vitro study of the activity of moxifloxacin and other antibiotics against 150 strains of penicillin non-susceptible Streptococcus pneumoniae and against 110 strains of ampicillin-resistant Haemophilus influenzae isolated in 1999–2000 in Spain
J. Antimicrob. Chemother. 2001 48: 145-148; doi:10.1093/jac/48.1.145 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

F.-J. Schmitz, M. Boos, S. Mayer, J. Verhoef, D. Milatovic, and A. C. Fluit

In vitro activity of faropenem and 21 other compounds against 385 different genetically characterized isolates of antibiotic-resistant Streptococcus pneumoniae
J. Antimicrob. Chemother. 2001 48: 148-152; doi:10.1093/jac/48.1.148 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Carmen Betriu, Ana Sánchez, M. Luisa Palau, María Gómez, and Juan J. Picazo

Antibiotic resistance surveillance of Stenotrophomonas maltophilia, 1993–1999
J. Antimicrob. Chemother. 2001 48: 152-154; doi:10.1093/jac/48.1.152 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

J. Zhang and A. M. Lovering

Difficulties in the assay of cefamandole highlight the importance of specific methodologies in pharmacokinetic studies
J. Antimicrob. Chemother. 2001 48: 154-155; doi:10.1093/jac/48.1.154 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Mark H. Wilcox, Alex Brown, and Jane Freeman

Faecal concentrations of piperacillin and tazobactam in elderly patients
J. Antimicrob. Chemother. 2001 48: 155-156; doi:10.1093/jac/48.1.155 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Book reviews:

Andrew Mackay

Management of Antimicrobials in Infectious Diseases: Impact of Antibiotic Resistance: A. G. Mainous and C. Pomeroy, Eds.Humana Press, Totowa, NJ, USA, 2001.ISBN 0-89603-821-1.
J. Antimicrob. Chemother. 2001 48: 157; doi:10.1093/jac/48.1.157 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Soraya Dhillon

Drug Interactions in Infectious Diseases: Stephen C. Piscitelli and Keith A. Rodvold, Eds. Humana Press, Totowa, New Jersey, USA, 2001. ISBN 0-89603-750-9.
J. Antimicrob. Chemother. 2001 48: 157-158; doi:10.1093/jac/48.1.157-a [Extract] [FREE Full Text] [PDF] [Request Permissions]  

C. Aitken

Viral Hepatitis: E. A. Fagan and T. J. Harrison, Eds. Bios Scientific Publishers Ltd, Oxford, 2000. ISBN 1 85916 0251.
J. Antimicrob. Chemother. 2001 48: 158-159; doi:10.1093/jac/48.1.158 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Erratum:

M. Wootton, R. A. Howe, R. Hillman, T. R. Walsh, P. M. Bennett, and A. P. MacGowan

A modified population analysis profile (PAP) method to detect hetero-resistance to vancomycin in Staphylococcus aureus in a UK hospital
J. Antimicrob. Chemother. 2001 48: 161; doi:10.1093/jac/48.1.161 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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