Journal of Antimicrobial Chemotherapy

Review:

Leonard Amaral, Jette E. Kristiansen, Miguel Viveiros, and Jorge Atouguia

Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: a review supporting further studies that may elucidate the potential use of thioridazine as anti-tuberculosis therapy
J. Antimicrob. Chemother. 2001 47: 505-511; doi:10.1093/jac/47.5.505 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Kang-Sik Park, Kap-Chul Kang, Ki-Young Kim, Pan-Young Jeong, Jai-Hyun Kim, David J. Adams, Jung-Ho Kim, and Young-Ki Paik

HWY-289, a novel semi-synthetic protoberberine derivative with multiple target sites in Candida albicans
J. Antimicrob. Chemother. 2001 47: 513-519; doi:10.1093/jac/47.5.513 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Maiken Arendrup, Bettina Lundgren, Irene Møller Jensen, Bo Sønder Hansen, and Niels Frimodt-Møller

Comparison of Etest and a tablet diffusion test with the NCCLS broth microdilution method for fluconazole and amphotericin B susceptibility testing of Candida isolates
J. Antimicrob. Chemother. 2001 47: 521-526; doi:10.1093/jac/47.5.521 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Kazunori Maebashi, Masakazu Niimi, Michinari Kudoh, Frank J. Fischer, Koichi Makimura, Kyoko Niimi, R. Jane Piper, Katsuhisa Uchida, Mikio Arisawa, Richard D. Cannon, and Hideyo Yamaguchi

Mechanisms of fluconazole resistance in Candida albicans isolates from Japanese AIDS patients
J. Antimicrob. Chemother. 2001 47: 527-536; doi:10.1093/jac/47.5.527 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Renee Lira, Lellys Mariela Contreras, Ricardo M. Santa Rita, and Julio A. Urbina

Mechanism of action of anti-proliferative lysophospholipid analogues against the protozoan parasite Trypanosoma cruzi: potentiation of in vitro activity by the sterol biosynthesis inhibitor ketoconazole
J. Antimicrob. Chemother. 2001 47: 537-546; doi:10.1093/jac/47.5.537 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Corinne C. Randegger and Herbert Hächler

Amino acid substitutions causing inhibitor resistance in TEM ß-lactamases compromise the extended-spectrum phenotype in SHV extended-spectrum ß-lactamases
J. Antimicrob. Chemother. 2001 47: 547-554; doi:10.1093/jac/47.5.547 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Joanne L. Simala-Grant, David Zopf, and Diane E. Taylor

Antibiotic susceptibility of attached and free-floating Helicobacter pylori
J. Antimicrob. Chemother. 2001 47: 555-563; doi:10.1093/jac/47.5.555 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Shigeharu Inouye, Toshio Takizawa, and Hideyo Yamaguchi

Antibacterial activity of essential oils and their major constituents against respiratory tract pathogens by gaseous contact
J. Antimicrob. Chemother. 2001 47: 565-573; doi:10.1093/jac/47.5.565 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Charlotte M. A. Linde, Sven E. Hoffner, Essam Refai, and Mats Andersson

In vitro activity of PR-39, a proline-arginine-rich peptide, against susceptible and multi-drug-resistant Mycobacterium tuberculosis
J. Antimicrob. Chemother. 2001 47: 575-580; doi:10.1093/jac/47.5.575 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Steven J. Martin, Cory G. Garvin, Christopher R. McBurney, and Eric G. Sahloff

The activity of 14-hydroxy clarithromycin, alone and in combination with clarithromycin, against penicillin- and erythromycin-resistant Streptococcus pneumoniae
J. Antimicrob. Chemother. 2001 47: 581-587; doi:10.1093/jac/47.5.581 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

S. M. Tambe, L. Sampath, and S. M. Modak

In vitro evaluation of the risk of developing bacterial resistance to antiseptics and antibiotics used in medical devices
J. Antimicrob. Chemother. 2001 47: 589-598; doi:10.1093/jac/47.5.589 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Je Chul Lee, Jae Young Oh, Jae We Cho, Jong Chun Park, Jung Min Kim, Sung Yong Seol, and Dong Taek Cho

The prevalence of trimethoprim-resistance-conferring dihydrofolate reductase genes in urinary isolates of Escherichia coli in Korea
J. Antimicrob. Chemother. 2001 47: 599-604; doi:10.1093/jac/47.5.599 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M. R. Millar, T. R. Walsh, C. J. Linton, S. Zhang, J. P. Leeming, and P. M. Bennett

Carriage of antibiotic-resistant bacteria by healthy children
J. Antimicrob. Chemother. 2001 47: 605-610; doi:10.1093/jac/47.5.605 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Christopher J. Destache, Catherine B. Pakiz, Chris Larsen, Heather Owens, and Alekha K. Dash

Cerebrospinal fluid penetration and pharmacokinetics of levofloxacin in an experimental rabbit meningitis model
J. Antimicrob. Chemother. 2001 47: 611-615; doi:10.1093/jac/47.5.611 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Marie-Aline Robaux, Laurent Dube, Jocelyne Caillon, Denis Bugnon, Marie-France Kergueris, Dominique Navas, Philippe Le Conte, Denis Baron, and Gilles Potel

In vivo efficacy of continuous infusion versus intermittent dosing of ceftazidime alone or in combination with amikacin relative to human kinetic profiles in a Pseudomonas aeruginosa rabbit endocarditis model
J. Antimicrob. Chemother. 2001 47: 617-622; doi:10.1093/jac/47.5.617 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

F. López Fornas, F. Martínez García, J. Pérez Salmeron, D. Roldán Conesa, R. Cortés Sanchez, A. García Alberola, J. Ruíz Gómez, J. Gómez Gómez, and M. Valdés Chávarri

Comparative study of treatment with penicillin, ceftriaxone, trovafloxacin, quinupristin–dalfopristin and vancomycin in experimental endocarditis due to penicillin- and ceftriaxone-resistant Streptococcus pneumoniae
J. Antimicrob. Chemother. 2001 47: 623-629; doi:10.1093/jac/47.5.623 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Takashi Yoshii, Hidetaka Nishimura, Tomohiro Yoshikawa, Shungo Furudoi, Ayumi Yoshioka, Iwao Takenono, Yoshiki Ohtsuka, and Takahide Komori

Therapeutic possibilities of long-term roxithromycin treatment for chronic diffuse sclerosing osteomyelitis of the mandible
J. Antimicrob. Chemother. 2001 47: 631-637; doi:10.1093/jac/47.5.631 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Susan J. Rehm, Donald R. Graham, Latha Srinath, Philippe Prokocimer, Marie-Paule Richard, and George H. Talbot

Successful administration of quinupristin/dalfopristin in the outpatient setting
J. Antimicrob. Chemother. 2001 47: 639-645; doi:10.1093/jac/47.5.639 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Alex J. O'Neill, Jonathan H. Cove, and Ian Chopra

Mutation frequencies for resistance to fusidic acid and rifampicin in Staphylococcus aureus
J. Antimicrob. Chemother. 2001 47: 647-650; doi:10.1093/jac/47.5.647 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Leticia Zarantonelli, Graciela Borthagaray, Eun Hee Lee, Wendy Veal, and William M. Shafer

Decreased susceptibility to azithromycin and erythromycin mediated by a novel mtr(R) promoter mutation in Neisseria gonorrhoeae
J. Antimicrob. Chemother. 2001 47: 651-654; doi:10.1093/jac/47.5.651 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

P. L. Ho, W. C. Yam, T. L. Que, D. N. C. Tsang, W. H. Seto, T. K. Ng, and W. S. Ng

Target site modifications and efflux phenotype in clinical isolates of Streptococcus pneumoniae from Hong Kong with reduced susceptibility to fluoroquinolones
J. Antimicrob. Chemother. 2001 47: 655-658; doi:10.1093/jac/47.5.655 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

P. G. Hermans, C. A. Hart, and A. J. Trees

In vitro activity of antimicrobial agents against the endosymbiont Wolbachia pipientis
J. Antimicrob. Chemother. 2001 47: 659-663; doi:10.1093/jac/47.5.659 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Shyh-ming Tsao and Mei-chin Yin

In vitro activity of garlic oil and four diallyl sulphides against antibiotic-resistant Pseudomonas aeruginosa and Klebsiella pneumoniae
J. Antimicrob. Chemother. 2001 47: 665-670; doi:10.1093/jac/47.5.665 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Erica J. Schmidt, J. Scott Boswell, Joshua P. Walsh, Matthew M. Schellenberg, Timothy W. Winter, Chunhong Li, Glenn W. Allman, and Paul B. Savage

Activities of cholic acid-derived antimicrobial agents against multidrug-resistant bacteria
J. Antimicrob. Chemother. 2001 47: 671-674; doi:10.1093/jac/47.5.671 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

F. Tubau, R. Fernández-Roblas, J. Liñares, R. Martín, and F. Soriano

In vitro activity of linezolid and 11 other antimicrobials against 566 clinical isolates and comparison between NCCLS microdilution and Etest methods
J. Antimicrob. Chemother. 2001 47: 675-680; doi:10.1093/jac/47.5.675 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Fernando García-Garrote, Emilia Cercenado, Jesús Martín-Pedroviejo, Oscar Cuevas, and Emilio Bouza

Comparative in vitro activity of the new quinolone gemifloxacin (SB-265805) with other fluoroquinolones against respiratory tract pathogens
J. Antimicrob. Chemother. 2001 47: 681-684; doi:10.1093/jac/47.5.681 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Nicolas Fortineau, Thierry Naas, Olivier Gaillot, and Patrice Nordmann

SHV-type extended-spectrum ß-lactamase in a Shigella flexneri clinical isolate
J. Antimicrob. Chemother. 2001 47: 685-688; doi:10.1093/jac/47.5.685 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

S. Zwart, G. J. H. M. Ruijs, A. P. E. Sachs, J. F. P. Schellekens, and R. A. de Melker

Potentially virulent strains and high colony counts of group A ß-haemolytic streptococci in pharyngitis patients having a delayed recovery or a complication
J. Antimicrob. Chemother. 2001 47: 689-691; doi:10.1093/jac/47.5.689 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

H. F. Kennedy, C. G. Gemmell, J. Bagg, B. E. S. Gibson, and J. R. Michie

Antimicrobial susceptibility of blood culture isolates of viridans streptococci: relationship to a change in empirical antibiotic therapy in febrile neutropenia
J. Antimicrob. Chemother. 2001 47: 693-696; doi:10.1093/jac/47.5.693 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Albert Musafija, Yuri Shtelman, Jacob Ramon, Moshe Volk, Shlomo Segev, and Ethan Rubinstein

The effect of Escherichia coli heat-stable toxin on the trans-epithelial intestinal elimination of ciprofloxacin in the rabbit
J. Antimicrob. Chemother. 2001 47: 697-699; doi:10.1093/jac/47.5.697 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Martin Perrig, Fernando Acosta, Marianne Cottagnoud, Cynthia M. Gerber, Martin G. Täuber, and Philippe Cottagnoud

Efficacy of gatifloxacin alone and in combination with cefepime against penicillin-resistant Streptococcus pneumoniae in a rabbit meningitis model and in vitro
J. Antimicrob. Chemother. 2001 47: 701-704; doi:10.1093/jac/47.5.701 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Mark E. Rupp, Paul D. Fey, and G. Matthew Longo

Effect of LY333328 against vancomycin-resistant Enterococcus faecium in a rat central venous catheter-associated infection model
J. Antimicrob. Chemother. 2001 47: 705-707; doi:10.1093/jac/47.5.705 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ichiko Sakamoto, Muneki Igarashi, Katsunori Kimura, Atsushi Takagi, Takeshi Miwa, and Yasuhiro Koga

Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans
J. Antimicrob. Chemother. 2001 47: 709-710; doi:10.1093/jac/47.5.709 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

R. Delcenserie, M. P. Dellion-Lozinguez, T. Yzet, B. Lepointe, L. Hary, R. Badoui, P. Verhaeghe, M. Andrejak, and J. L. Dupas

Pancreatic concentrations of cefepime
J. Antimicrob. Chemother. 2001 47: 711-713; doi:10.1093/jac/47.5.711 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Isabel Pujol, Joan Fernández-Ballart, and Josep Guarro

Effect of inoculum form on in vitro antifungal susceptibilities of Aspergillus spp.
J. Antimicrob. Chemother. 2001 47: 715-718; doi:10.1093/jac/47.5.715 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

Jane Freeman and Mark H. Wilcox

Ureidopenicillins and risk of Clostridium difficile infection
J. Antimicrob. Chemother. 2001 47: 719. [Extract] [FREE Full Text] [PDF] [Request Permissions]  

M. J. Weinbren

Pharmacokinetics of antibiotics in burns patients
J. Antimicrob. Chemother. 2001 47: 720. [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Keith J. Williams and David W. Denning

Termination of development of D0870
J. Antimicrob. Chemother. 2001 47: 720-721. [Extract] [FREE Full Text] [PDF] [Request Permissions]  

David Taylor-Robinson and Ronald C. Ballard

In vitro inactivation of Chlamydia trachomatis and of a panel of DNA (HSV-2, CMV, adenovirus, BK virus) and RNA (RSV, enterovirus) viruses by the spermicide benzalkonium chloride
J. Antimicrob. Chemother. 2001 47: 721-722. [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Grit Ackermann, Yajarayma J. Tang, Arne C. Rodloff, Joseph Silva, Jr, Stuart H. Cohen, and Peter Heisig

In vitro activity of sitafloxacin against Clostridium difficile
J. Antimicrob. Chemother. 2001 47: 722-724. [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Alim Isnansetyo, Miho Horikawa, and Yuto Kamei

In vitro anti-methicillin-resistant Staphylococcus aureus activity of 2,4-diacetylphloroglucinol produced by Pseudomonas sp. AMSN isolated from a marine alga
J. Antimicrob. Chemother. 2001 47: 724-725. [Extract] [FREE Full Text] [PDF] [Request Permissions]  

X. Bertrand and D. Talon

In vitro activity of co-amoxiclav acid against clinical isolates of Escherichia coli
J. Antimicrob. Chemother. 2001 47: 725-726. [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Iciar Rodríguez-Avial, Carmen Rodríguez-Avial, Esther Culebras, Antonio Benítez, and Juan J. Picazo

Distribution of mef(A) and erm(B) genes in macrolide-resistant blood isolates of viridans group streptococci
J. Antimicrob. Chemother. 2001 47: 727-728; doi:10.1093/jac/47.5.727 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Brendan D. Crowley

Extended-spectrum ß-lactamases in blood culture isolates of Klebsiella pneumoniae: seek and you may find!
J. Antimicrob. Chemother. 2001 47: 728-729. [Extract] [FREE Full Text] [PDF] [Request Permissions]  

H. von Baum, S. Böttcher, H. Hoffmann, and H.-G. Sonntag

Tissue penetration of a single dose of levofloxacin intravenously for antibiotic prophylaxis in lung surgery
J. Antimicrob. Chemother. 2001 47: 729-730. [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Book reviews:

Roger Freeman

Antimicrobial Chemotherapy. Fourth edition: Greenwood, D., Ed. Oxford University Press, Oxford, 2000. ISBN 0-19-263195-0. £29.95.
J. Antimicrob. Chemother. 2001 47: 731; doi:10.1093/jac/47.5.731 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

D. M. Livermore

Methods in Molecular Medicine. Antibiotic Resistance, Methods and Protocols: S. H. Gillespie, Ed. Humana Press, Totowa, NJ, 2001. ISBN 0-89603-777-0. $89.50.
J. Antimicrob. Chemother. 2001 47: 731-732; doi:10.1093/jac/47.5.731-a [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Deenan Pillay

Antivirals Against AIDS: R. E. Unger, J. Kreuter & H. Rubsamen-Waigmann. Marcel Dekker, Inc., New York, NY, 2000.ISBN 0-8427-0358-8. $150.00.
J. Antimicrob. Chemother. 2001 47: 732-733; doi:10.1093/jac/47.5.732 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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