Journal of Antimicrobial Chemotherapy

Leading articles:

David M. Livermore

Quinupristin/dalfopristin and linezolid: where, when, which and whether to use?
J. Antimicrob. Chemother. 2000 46: 347-350; doi:10.1093/jac/46.3.347 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Review:

M. J. M. Bonten, B. J. Kullberg, R. van Dalen, A. R. J. Girbes, I. M. Hoepelman, W. Hustinx, J. W. M. van der Meer, P. Speelman, E. E. Stobberingh, H. A. Verbrugh, J. Verhoef, and J. H. Zwaveling

Selective digestive decontamination in patients in intensive care
J. Antimicrob. Chemother. 2000 46: 351-362; doi:10.1093/jac/46.3.351 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Masami Tagawa, Taketo Yamaguchi, Osamu Yokosuka, Shoichi Matsutani, Toyoyuki Maeda, and Hiromitsu Saisho

Inactivation of a hepadnavirus by electrolysed acid water
J. Antimicrob. Chemother. 2000 46: 363-368; doi:10.1093/jac/46.3.363 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

L. M. Koeth, A. King, H. Knight, J. May, L. A. Miller, I. Phillips, and J. A. Poupard

Comparison of cation-adjusted Mueller–Hinton broth with Iso-Sensitest broth for the NCCLS broth microdilution method
J. Antimicrob. Chemother. 2000 46: 369-376; doi:10.1093/jac/46.3.369 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Karen A. Krogfelt, Maryjane Utley, Howard C. Krivan, David C. Laux, and Paul S. Cohen

Specific phospholipids enhance the activity of ß-lactam antibiotics against Pseudomonas aeruginosa
J. Antimicrob. Chemother. 2000 46: 377-384; doi:10.1093/jac/46.3.377 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Daniel Jonas, Inge Engels, Franz D. Daschner, and Uwe Frank

The effect of azithromycin on intracellular Legionella pneumophila in the Mono Mac 6 cell line at serum concentrations attainable in vivo
J. Antimicrob. Chemother. 2000 46: 385-390; doi:10.1093/jac/46.3.385 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Suzana Bosne-David, Vanessa Barros, Sandra Cabo Verde, Clara Portugal, and Hugo L. David

Intrinsic resistance of Mycobacterium tuberculosis to clarithromycin is effectively reversed by subinhibitory concentrations of cell wall inhibitors
J. Antimicrob. Chemother. 2000 46: 391-395; doi:10.1093/jac/46.3.391 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

George S. Baillie and L. Julia Douglas

Matrix polymers of Candida biofilms and their possible role in biofilm resistance to antifungal agents
J. Antimicrob. Chemother. 2000 46: 397-403; doi:10.1093/jac/46.3.397 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Kere Kobayashi, Min Rao, Stefanie Keis, Frederick A. Rainey, John M. B. Smith, and Gregory M. Cook

Enterococci with reduced susceptibility to vancomycin in New Zealand
J. Antimicrob. Chemother. 2000 46: 405-410; doi:10.1093/jac/46.3.405 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

David M. Livermore, Peter Stephens, Julius Weinberg, Alan P. Johnson, Tiffany Gifford, Dorabella Northcott, Dorothy James, Robert C. George, and David C. E. Speller

Regional variation in ampicillin and trimethoprim resistance in Escherichia coli in England from 1990 to 1997, in relation to antibacterial prescribing
J. Antimicrob. Chemother. 2000 46: 411-422; doi:10.1093/jac/46.3.411 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Heinz Winkler, Oskar Janata, Christian Berger, Wolfgang Wein, and Apostolos Georgopoulos

In vitro release of vancomycin and tobramycin from impregnated human and bovine bone grafts
J. Antimicrob. Chemother. 2000 46: 423-428; doi:10.1093/jac/46.3.423 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Cyprian O. Onyeji, David P. Nicolau, Charles H. Nightingale, and Laurine Bow

Modulation of efficacies and pharmacokinetics of antibiotics by granulocyte colony-stimulating factor in neutropenic mice with multidrug-resistant Enterococcus faecalis infection
J. Antimicrob. Chemother. 2000 46: 429-436; doi:10.1093/jac/46.3.429 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jon E. Lutz, Karl V. Clemons, and David A. Stevens

Enhancement of antifungal chemotherapy by interferon-gamma in experimental systemic cryptococcosis
J. Antimicrob. Chemother. 2000 46: 437-442; doi:10.1093/jac/46.3.437 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Katsunori Furukawa, Hidetaka Sasaki, Richard B. Pollard, and Fujio Suzuki

Lanoconazole, a new imidazole antimycotic compound, protects MAIDS mice against encephalitis caused by Cryptococcus neoformans
J. Antimicrob. Chemother. 2000 46: 443-450; doi:10.1093/jac/46.3.443 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Stefan Reuter, Björn Jensen, Klaus Buttenschoen, Wolfgang Kratzer, and Peter Kern

Benzimidazoles in the treatment of alveolar echinococcosis: a comparative study and review of the literature
J. Antimicrob. Chemother. 2000 46: 451-456; doi:10.1093/jac/46.3.451 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Pål Voltersvik, Alfred Halstensen, Nina Langeland, Asbjørn Digranes, Lars Erik Peterson, Tore Rolstad, and Claus Ola Solberg

Eradication of non-typhoid salmonellae in acute enteritis after therapy with ofloxacin for 5 or 10 days
J. Antimicrob. Chemother. 2000 46: 457-459; doi:10.1093/jac/46.3.457 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Jill A. Rebuck, Keith M. Olsen, Paul D. Fey, Kimberly L. Bergman, and Mark E. Rupp

In vitro activities of parenteral ß-lactam antimicrobials against TEM-10-, TEM-26- and SHV-5-derived extended-spectrum ß-lactamases expressed in an isogenic Escherichia coli host
J. Antimicrob. Chemother. 2000 46: 461-464; doi:10.1093/jac/46.3.461 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Kaori Tanaka, Naoki Kato, and Kunitomo Watanabe

In vitro activity of an evernimicin derivative, SCH27899, against anaerobic bacteria and Propionibacterium acnes
J. Antimicrob. Chemother. 2000 46: 465-469; doi:10.1093/jac/46.3.465 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Hiroshige Mikamo, Koji Izumi, Yin Xiang Hua, Yoh Hayasaki, Yasumasa Sato, and Teruhiko Tamaya

In vitro and in vivo antibacterial activities of a new injectable carbapenem, S-4661, against gynaecological pathogens
J. Antimicrob. Chemother. 2000 46: 471-474; doi:10.1093/jac/46.3.471 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Manuel Cuenca-Estrella, Emilia Mellado, Teresa M. Díaz-Guerra, Araceli Monzón, and Juan L. Rodríguez-Tudela

Susceptibility of fluconazole-resistant clinical isolates of Candida spp. to echinocandin LY303366, itraconazole and amphotericin B
J. Antimicrob. Chemother. 2000 46: 475-477; doi:10.1093/jac/46.3.475 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Corrado Girmenia, Clelia Tuccinardi, Stefania Santilli, Francesca Mondello, Monica Monaco, Antonio Cassone, and Pietro Martino

In vitro activity of fluconazole and voriconazole against isolates of Candida albicans from patients with haematological malignancies
J. Antimicrob. Chemother. 2000 46: 479-484; doi:10.1093/jac/46.3.479 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Hiroshige Mikamo, Yasumasa Sato, and Teruhiko Tamaya

In vitro antifungal activity of FK463, a new water-soluble echinocandin-like lipopeptide
J. Antimicrob. Chemother. 2000 46: 485-487; doi:10.1093/jac/46.3.485 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Anis A. Khan, Fausto G. Araujo, J. Carl Craft, and Jack S. Remington

Ketolide ABT-773 is active against Toxoplasma gondii
J. Antimicrob. Chemother. 2000 46: 489-492; doi:10.1093/jac/46.3.489 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Antimicrobial practice:

Cliodna A. M. McNulty, Alan Kane, Chris J. W. Foy, Jackie Sykes, Pamela Saunders, and Keith A. V. Cartwright

Primary care workshops can reduce and rationalize antibiotic prescribing
J. Antimicrob. Chemother. 2000 46: 493-499; doi:10.1093/jac/46.3.493 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Marie Thuong, Frédérique Shortgen, Virginie Zazempa, Emmanuelle Girou, Claude J. Soussy, and Christian Brun-Buisson

Appropriate use of restricted antimicrobial agents in hospitals: the importance of empirical therapy and assisted re-evaluation
J. Antimicrob. Chemother. 2000 46: 501-508; doi:10.1093/jac/46.3.501 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

D. T. Steinke, D. J. G. Bain, T. M. MacDonald, and P. G. Davey

Practice factors that influence antibiotic prescribing in general practice in Tayside
J. Antimicrob. Chemother. 2000 46: 509-512; doi:10.1093/jac/46.3.509 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

E. Tzelepi, M. Arvanitidou, L. S. Tzouvelekis, A. Mavroidi, and A. Tsakris

The isoelectric focusing patterns of ß-lactamases of Yersinia intermedia isolates from aquatic environments
J. Antimicrob. Chemother. 2000 46: 513-515; doi:10.1093/jac/46.3.513 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

A. Jenney, C. Franklin, L. Liolios, and D. Spelman

Enterococcus durans VanB
J. Antimicrob. Chemother. 2000 46: 515; doi:10.1093/jac/46.3.515 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Tony Worthington, Peter Lambert, and Tom Elliott

A novel serological test for the laboratory diagnosis of central venous catheter-associated sepsis
J. Antimicrob. Chemother. 2000 46: 516; doi:10.1093/jac/46.3.516 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

P. J. van den Broek, L. G. Visser, R. Bohte, and J. Van't Wout

Early diagnosis of pneumococcal pneumonia
J. Antimicrob. Chemother. 2000 46: 517; doi:10.1093/jac/46.3.517 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Jan M. Prins, Jeannine F. J. B. Nellen, Richard P. Koopmans, Pim N. J. Langendijk, Patrick M. M. Bossuyt, and Peter Speelman

Electronic drug ordering system can be helpful to implement iv–oral switch guidelines
J. Antimicrob. Chemother. 2000 46: 518-519; doi:10.1093/jac/46.3.518 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Book reviews:

Steven Kaye

Antiviral Methods and Protocols
J. Antimicrob. Chemother. 2000 46: 521; doi:10.1093/jac/46.3.521 [Extract] [FREE Full Text] [Request Permissions]  

R. G. Masterton

The Edinburgh City Hospital.

Matrons, Medics and Maladies. Edinburgh Royal Infirmary in the 1840s.

J. Antimicrob. Chemother. 2000 46: 521-522; doi:10.1093/jac/46.3.521-b [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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