Journal of Antimicrobial Chemotherapy

Leading articles:

Peter Ball

Quinolone-induced QT interval prolongation: a not-so-unexpected class effect
J. Antimicrob. Chemother. 2000 45: 557-559; doi:10.1093/jac/45.5.557 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Editorial:

David I. Edwards

Journal of Antimicrobial Chemotherapy online: a personal guide
J. Antimicrob. Chemother. 2000 45: 561-563; doi:10.1093/jac/45.5.561 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

S. Simjee, S. E. Manzoor, A. P. Fraise, and M. J. Gill

Nature of transposon-mediated high-level gentamicin resistance in Enterococcus faecalis isolated in the United Kingdom
J. Antimicrob. Chemother. 2000 45: 565-575; doi:10.1093/jac/45.5.565 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Alessandra R. Arzese, Lara Tomasetig, and Giuseppe A. Botta

Detection of tetQ and ermF antibiotic resistance genes in Prevotella and Porphyromonas isolates from clinical specimens and resident microbiota of humans
J. Antimicrob. Chemother. 2000 45: 577-582; doi:10.1093/jac/45.5.577 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ekaterina Pestova, John J. Millichap, Gary A. Noskin, and Lance R. Peterson

Intracellular targets of moxifloxacin: a comparison with other fluoroquinolones
J. Antimicrob. Chemother. 2000 45: 583-590; doi:10.1093/jac/45.5.583 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Andrew G. Harris, Stuart L. Hazell, and Andrew G. Netting

Use of digoxigenin-labelled ampicillin in the identification of penicillin-binding proteins in Helicobacter pylori
J. Antimicrob. Chemother. 2000 45: 591-598; doi:10.1093/jac/45.5.591 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

N. I. Leaves, I. Dimopoulou, I. Hayes, S. Kerridge, T. Falla, O. Secka, R. A. Adegbola, M. P. E. Slack, T. E. A. Peto, and D. W. M. Crook

Epidemiological studies of large resistance plasmids in Haemophilus
J. Antimicrob. Chemother. 2000 45: 599-604; doi:10.1093/jac/45.5.599 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

J. I. Alós, B. Aracil, J. Oteo, C. Torres, J. L. Gómez-Garcés, and the Spanish Group for the Study of Infection in the Primary Health care Setting

High prevalence of erythromycin-resistant, clindamycin/miocamycin-susceptible (M phenotype) Streptococcus pyogenes: results of a Spanish multicentre study in 1998
J. Antimicrob. Chemother. 2000 45: 605-609; doi:10.1093/jac/45.5.605 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

H. Barroso, A. Freitas-Vieira, L. M. Lito, J. Melo Cristino, M. J. Salgado, H. Ferreira Neto, J. C. Sousa, G. Soveral, T. Moura, and A. Duarte

Survey of Klebsiella pneumoniae producing extended-spectrum ß-lactamases at a Portuguese hospital: TEM-10 as the endemic enzyme
J. Antimicrob. Chemother. 2000 45: 611-616; doi:10.1093/jac/45.5.611 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. A. Al-Jabri, M. D. Wigg, E. Elias, R. Lambkin, C. O. Mills, and J. S. Oxford

In vitro anti-HIV-1 virucidal activity of tyrosine-conjugated tri- and dihydroxy bile salt derivatives
J. Antimicrob. Chemother. 2000 45: 617-621; doi:10.1093/jac/45.5.617 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Edward O. Mason, Jr, Linda B. Lamberth, Nerisa L. Kershaw, Barbara La T. Prosser, Annette Zoe, and Paul G. Ambrose

Streptococcus pneumoniae in the USA: in vitro susceptibility and pharmacodynamic analysis
J. Antimicrob. Chemother. 2000 45: 623-631; doi:10.1093/jac/45.5.623 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Lois M. Ednie, Kim L. Credito, Mayuree Khantipong, Michael R. Jacobs, and Peter C. Appelbaum

Synergic activity, for anaerobes, of trovafloxacin with clindamycin or metronidazole: chequerboard and time–kill methods
J. Antimicrob. Chemother. 2000 45: 633-638; doi:10.1093/jac/45.5.633 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

J. May, C. H. Chan, A. King, L. Williams, and G. L. French

Time–kill studies of tea tree oils on clinical isolates
J. Antimicrob. Chemother. 2000 45: 639-643; doi:10.1093/jac/45.5.639 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

O. López-Jodra, J. M. Torres-Rodríguez, R. Méndez-Vásquez, E. Ribas-Forcadell, Y. Morera-López, T. Baró-Tomás, and C. Alia-Aponte

In vitro susceptibility of Cryptococcus neoformans isolates to five antifungal drugs using a colorimetric system and the reference microbroth method
J. Antimicrob. Chemother. 2000 45: 645-649; doi:10.1093/jac/45.5.645 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Andrea Giacometti, Oscar Cirioni, Francesco Barchiesi, Fausto Ancarani, and Giorgio Scalise

In vitro anti-cryptosporidial activity of cationic peptides alone and in combination with inhibitors of ion transport systems
J. Antimicrob. Chemother. 2000 45: 651-654; doi:10.1093/jac/45.5.651 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

George G. Zhanel, James A. Karlowsky, Donald E. Low, the Canadian Respiratory Infection Study Group, and Daryl J. Hoban

Antibiotic resistance in respiratory tract isolates of Haemophilus influenzae and Moraxella catarrhalis collected from across Canada in 1997–1998
J. Antimicrob. Chemother. 2000 45: 655-662; doi:10.1093/jac/45.5.655 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. E. J. M. van den Bogaard, N. London, and E. E. Stobberingh

Antimicrobial resistance in pig faecal samples from The Netherlands (five abattoirs) and Sweden
J. Antimicrob. Chemother. 2000 45: 663-671; doi:10.1093/jac/45.5.663 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

P. H. Chandrasekar, Jessica Cutright, and Elias Manavathu

Efficacy of voriconazole against invasive pulmonary aspergillosis in a guinea-pig model
J. Antimicrob. Chemother. 2000 45: 673-676; doi:10.1093/jac/45.5.673 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Anette Marie Hammerum, Vivian Fussing, Frank Møller Aarestrup, and Henrik Caspar Wegener

Characterization of vancomycin-resistant and vancomycin-susceptible Enterococcus faecium isolates from humans, chickens and pigs by RiboPrinting and pulsed-field gel electrophoresis
J. Antimicrob. Chemother. 2000 45: 677-680; doi:10.1093/jac/45.5.677 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Laura J. V. Piddock and Vito Ricci

Accumulation of KRM-1648 by Mycobacterium aurum and Mycobacterium tuberculosis
J. Antimicrob. Chemother. 2000 45: 681-684; doi:10.1093/jac/45.5.681 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Youko Tsurumaki, Hinako Manda, Masaya Takei, and Masaki Hosaka

In vitro antimicrobial activity of gatifloxacin against 873 clinical isolates from respiratory tract, urinary tract and surgical infections during 1997–1998 in Japan
J. Antimicrob. Chemother. 2000 45: 685-689; doi:10.1093/jac/45.5.685 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

J. Oteo, B. Aracil, J. I. Alós, and J. L. Gómez-Garcés

High prevalence of resistance to clindamycin in Bacteroides fragilis group isolates
J. Antimicrob. Chemother. 2000 45: 691-693; doi:10.1093/jac/45.5.691 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Study group: Sebahat Aksaray, Basak Dokuzoguz, Engin Güvener, Mine Yücesoy, Nuran Yulug, Sesin Kocagöz, Serhat Ünal, Sila Çetin, Semra Çalangu, Murat Günaydin, Hakan Leblebicioglu, Saban Esen, Banu Bayar, Ayse Willke, Duygu Findik, Inci Tuncer, Bülent Baysal, Filiz Günseren, and Latife Mamikoglu

Surveillance of antimicrobial resistance among Gram-negative isolates from intensive care units in eight hospitals in Turkey
J. Antimicrob. Chemother. 2000 45: 695-699; doi:10.1093/jac/45.5.695 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Matti Valtonen, Eero Tiula, Janne T. Backman, and Pertti J. Neuvonen

Elimination of meropenem during continuous veno-venous haemofiltration and haemodiafiltration in patients with acute renal failure
J. Antimicrob. Chemother. 2000 45: 701-704; doi:10.1093/jac/45.5.701 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Robert Cunney, Hiba Abdel Aziz, Darlene Schubert, Eleanor McNamara, and Edmond Smyth

Interpretative reporting and selective antimicrobial susceptibility release in non-critical microbiology results
J. Antimicrob. Chemother. 2000 45: 705-708; doi:10.1093/jac/45.5.705 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

G. S. Tillotson and L. R. Peterson

Quinolones and pneumococci
J. Antimicrob. Chemother. 2000 45: 709-710; doi:10.1093/jac/45.5.709 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

David Felmingham, Yese Tesfaslasie, Carol Burley, and Robert G. Masterton

Penicillin resistance in pneumococci
J. Antimicrob. Chemother. 2000 45: 710-711; doi:10.1093/jac/45.5.710 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Helia Bello, Mariana Domínguez, Gerardo González, Raúl Zemelman, Sergio Mella, Hilary-Kay Young, and Sebastian G. B. Amyes

In vitro activities of ampicillin, sulbactam and a combination of ampicillin and sulbactam against isolates of Acinetobacter calcoaceticus–Acinetobacter baumannii complex isolated in Chile between 1990 and 1998
J. Antimicrob. Chemother. 2000 45: 712-713; doi:10.1093/jac/45.5.712 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

A. Robert Neurath, Yun-Yao Li, Rosemonde Mandeville, and Lucie Richard

In vitro activity of a cellulose acetate phthalate topical cream against organisms associated with bacterial vaginosis
J. Antimicrob. Chemother. 2000 45: 713-714; doi:10.1093/jac/45.5.713 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

G. Gopal Rao

Should clindamycin be used in treatment of patients with infections caused by erythromycin-resistant staphylococci?
J. Antimicrob. Chemother. 2000 45: 715; doi:10.1093/jac/45.5.715 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Stephen Taylor, Jane Little, Kathryn Halifax, Susan Drake, and David Back

Pharmacokinetics of nelfinavir and nevirapine in a patient with end-stage renal failure on continuous ambulatory peritoneal dialysis
J. Antimicrob. Chemother. 2000 45: 716-717; doi:10.1093/jac/45.5.716 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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