Journal of Antimicrobial Chemotherapy

Leading articles:

Kevin G. Kerr

The prophylaxis of bacterial infections in neutropenic patients
J. Antimicrob. Chemother. 1999 44: 587-591; doi:10.1093/jac/44.5.587 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Anca van de Kerk-van Hoof and Albert J. R. Heck

Interactions of - and ß-avoparcin with bacterial cell-wall receptor-mimicking peptides studied by electrospray ionization mass spectrometry
J. Antimicrob. Chemother. 1999 44: 593-599; doi:10.1093/jac/44.5.593 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ching-Tsan Huang and Philip S. Stewart

Reduction of polysaccharide production in Pseudomonas aeruginosa biofilms by bismuth dimercaprol (BisBAL) treatment
J. Antimicrob. Chemother. 1999 44: 601-605; doi:10.1093/jac/44.5.601 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Patricia A. Bradford, Peter J. Petersen, Ian M. Fingerman, and David G. White

Characterization of expanded-spectrum cephalosporin resistance in E. coli isolates associated with bovine calf diarrhoeal disease
J. Antimicrob. Chemother. 1999 44: 607-610; doi:10.1093/jac/44.5.607 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

H. Hanberger, L. E. Nilsson, B. Claesson, A. Kärnell, P. Larsson, M. Rylander, E. Svensson, M. Sörberg, and L. Sörén

New species-related MIC breakpoints for early detection of development of resistance among Gram-negative bacteria in Swedish intensive care units
J. Antimicrob. Chemother. 1999 44: 611-619; doi:10.1093/jac/44.5.611 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Alice Pong, Kenneth S. Thomson, Ellen S. Moland, Stephen A. Chartrand, and Christine C. Sanders

Activity of moxifloxacin against pathogens with decreased susceptibility to ciprofloxacin
J. Antimicrob. Chemother. 1999 44: 621-627; doi:10.1093/jac/44.5.621 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Inger Adamsson, Carl Erik Nord, Per Lundquist, Svante Sjöstedt, and Charlotta Edlund

Comparative effects of omeprazole, amoxycillin plus metronidazole versus omeprazole, clarithromycin plus metronidazole on the oral, gastric and intestinal microflora in Helicobacter pylori-infected patients
J. Antimicrob. Chemother. 1999 44: 629-640; doi:10.1093/jac/44.5.629 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. Giacometti, O. Cirioni, F. Barchiesi, M. Fortuna, and G. Scalise

In-vitro activity of cationic peptides alone and in combination with clinically used antimicrobial agents against Pseudomonas aeruginosa
J. Antimicrob. Chemother. 1999 44: 641-645; doi:10.1093/jac/44.5.641 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

S. Vacher, J. L. Pellegrin, F. Leblanc, J. Fourche, and J. Maugein

Comparative antimycobacterial activities of ofloxacin, ciprofloxacin and grepafloxacin
J. Antimicrob. Chemother. 1999 44: 647-652; doi:10.1093/jac/44.5.647 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Oscar Cirioni, Andrea Giacometti, Francesco Barchiesi, Moira Fortuna, and Giorgio Scalise

In-vitro activity of rifabutin and albendazole singly and in combination with other clinically used antimicrobial agents against Pneumocystis carinii
J. Antimicrob. Chemother. 1999 44: 653-659; doi:10.1093/jac/44.5.653 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

K. E. Bowker, M. Wootton, C. A. Rogers, R. Lewis, H. A. Holt, and A. P. MacGowan

Comparison of in-vitro pharmacodynamics of once and twice daily ciprofloxacin
J. Antimicrob. Chemother. 1999 44: 661-667; doi:10.1093/jac/44.5.661 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

E. Van Wijngaerden, W. E. Peetermans, J. Vandersmissen, S. Van Lierde, H. Bobbaers, and J. Van Eldere

Foreign body infection: a new rat model for prophylaxis and treatment
J. Antimicrob. Chemother. 1999 44: 669-674; doi:10.1093/jac/44.5.669 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Robin A. Howe, Mandy Wootton, Timothy R. Walsh, Peter M. Bennett, and Alasdair P. MacGowan

Expression and detection of hetero-vancomycin resistance in Staphylococcus aureus
J. Antimicrob. Chemother. 1999 44: 675-678; doi:10.1093/jac/44.5.675 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

R. Wise and J. M. Andrews

The in-vitro activity and tentative breakpoint of gemifloxacin, a new fluoroquinolone
J. Antimicrob. Chemother. 1999 44: 679-688; doi:10.1093/jac/44.5.679 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Shigeharu Oie, Akihiro Sawa, Akira Kamiya, and Hidekazu Mizuno

In-vitro effects of a combination of antipseudomonal antibiotics against multi-drug resistant Pseudomonas aeruginosa
J. Antimicrob. Chemother. 1999 44: 689-691; doi:10.1093/jac/44.5.689 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. Tsakris, S. Alexiou-Daniel, E. Souliou, and A. Antoniadis

In-vitro activity of antibiotics against Legionella pneumophila isolates from water systems
J. Antimicrob. Chemother. 1999 44: 693-695; doi:10.1093/jac/44.5.693 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M. Chávez, S. Bernal, A. Valverde, M. J. Gutierrez, G. Quindós, and E. Martin Mazuelos

In-vitro activity of voriconazole (UK-109,496), LY303366 and other antifungal agents against oral Candida spp. isolates from HIV-infected patients
J. Antimicrob. Chemother. 1999 44: 697-700; doi:10.1093/jac/44.5.697 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

R. Wise, J. M. Andrews, J. P. Ashby, and J. Marshall

A study to determine the pharmacokinetics and inflammatory fluid penetration of gatifloxacin following a single oral dose
J. Antimicrob. Chemother. 1999 44: 701-704; doi:10.1093/jac/44.5.701 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Manuel Cotarelo, Pilar Catalán, Carlos Sánchez-Carrillo, Ana Menasalvas, Emilia Cercenado, Antonio Tenorio, and Emilio Bouza

Cytopathic effect inhibition assay for determining the in-vitro susceptibility of herpes simplex virus to antiviral agents
J. Antimicrob. Chemother. 1999 44: 705-708; doi:10.1093/jac/44.5.705 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Antimicrobial practice:

Fahad A. Al-Eidan, James C. McElnay, M. G. Scott, M. P. Kearney, K. E. U. Troughton, and J. Jenkins

Sequential antimicrobial therapy: treatment of severe lower respiratory tract infections in children
J. Antimicrob. Chemother. 1999 44: 709-715; doi:10.1093/jac/44.5.709 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

John D. Perry, Lynne A. Butterworth, Gavin Riley, and F. Kate Gould

Disc susceptibility testing of staphylococci-implications for the BSAC standardized method
J. Antimicrob. Chemother. 1999 44: 717-718; doi:10.1093/jac/44.5.717 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

M. F. Tripodi, A. Rambaldi, G. Sarnataro, E. Ragone, and R. Utili

The effects of the level of ampicillin resistance and the inoculum size on the in-vitro bactericidal activity of the combination of ampicillin and ciprofloxacin against high-level gentamicin-resistant strains of Enterococcus faecium
J. Antimicrob. Chemother. 1999 44: 719-720; doi:10.1093/jac/44.5.719 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Andreas F. Mentis, Eleftheria Roma, Anastasia Pangalis, and Evangelia Katsiyiannakis

Susceptibilities of Helicobacter pylori strains isolated from children with gastritis to selected antibiotics
J. Antimicrob. Chemother. 1999 44: 720-722; doi:10.1093/jac/44.5.720 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Book reviews:

Richard Ellis

Microbiology in Clinical Practice, 3rd edn
J. Antimicrob. Chemother. 1999 44: 723-724; doi:10.1093/jac/44.5.723 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

C. Aiken

Human Immunodeficiency Viruses
J. Antimicrob. Chemother. 1999 44: 723-724; doi:10.1093/jac/44.5.723-a [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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