Journal of Antimicrobial Chemotherapy

Leading articles:

Fred W. Goldstein

Penicillin-resistant Streptococcus pneumoniae: selection by both ß-lactam and non-ß-lactam antibiotics
J. Antimicrob. Chemother. 1999 44: 141-144; doi:10.1093/jac/44.2.141 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

P. J. Cook

Antimicrobial therapy for Chlamydia pneumoniae: its potential role in atherosclerosis and asthma
J. Antimicrob. Chemother. 1999 44: 145-148; doi:10.1093/jac/44.2.145 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Editorials:

M. J. Wood

Over-the-counter antibiotics
J. Antimicrob. Chemother. 1999 44: 149-150; doi:10.1093/jac/44.2.149 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

The 1998 Garrod Lecture:

Vincent T. Andriole

Current and future antifungal therapy: new targets for antifungal agents
J. Antimicrob. Chemother. 1999 44: 151-162; doi:10.1093/jac/44.2.151 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Working Party Report:

David S. Reeves, Roger G. Finch, Richard P. Bax, Peter G. Davey, Alan Li Wan Po, Geeta Lingam, Stephen G. Mann, and Michael A. L. Pringle

Self-medication of antibacterials without prescription (also called `over-the-counter' use): A report of a Working Party of the British Society for Antimicrobial Chemotherapy
J. Antimicrob. Chemother. 1999 44: 163-177; doi:10.1093/jac/44.2.163 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Gianpaolo Candiani, Monica Abbondi, Monica Borgonovi, Gabriella Romanò, and Franco Parenti

In-vitro and in-vivo antibacterial activity of BI 397, a new semi-synthetic glycopeptide antibiotic
J. Antimicrob. Chemother. 1999 44: 179-192; doi:10.1093/jac/44.2.179 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

P. J. van den Broek, T. G. A. Koot, E. van Strijen, and H. Mattie

Intracellular activity of trovafloxacin against Staphylococcus aureus
J. Antimicrob. Chemother. 1999 44: 193-199; doi:10.1093/jac/44.2.193 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Junichi Mitsuyama

Structures of existing and new quinolones and relationship to bactericidal activity against Streptococcus pneumoniae
J. Antimicrob. Chemother. 1999 44: 201-207; doi:10.1093/jac/44.2.201 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

H. C. Steel, N. M. Matlola, and R. Anderson

Inhibition of potassium transport and growth of mycobacteria exposed to clofazimine and B669 is associated with a calcium-independent increase in microbial phospholipase A₂ activity
J. Antimicrob. Chemother. 1999 44: 209-216; doi:10.1093/jac/44.2.209 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Avital Mazar Ben-Josef, Elias K. Manavathu, David Platt, and Jack D. Sobel

Involvement of calcium inhibitable binding to the cell wall in the fungicidal activity of CAN-296
J. Antimicrob. Chemother. 1999 44: 217-222; doi:10.1093/jac/44.2.217 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Maurizio Del Poeta, Amy S. Bixel, Francesco Barchiesi, Richard R. Tidwell, David Boykin, Giorgio Scalise, and John R. Perfect

In-vitro activity of dicationic aromatic compounds and fluconazole against Cryptococcus neoformans and Candida spp.
J. Antimicrob. Chemother. 1999 44: 223-228; doi:10.1093/jac/44.2.223 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Marc L. van Ogtrop

The antibacterial efficacy of trovafloxacin against an experimental infection with Listeria monocytogenes in hydrocortisone-treated mice
J. Antimicrob. Chemother. 1999 44: 229-234; doi:10.1093/jac/44.2.229 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

S. Romano, M. M. Fdez de Gatta, M. V. Calvo, D. Caballero, A. Dominguez-Gil, and J. M. Lanao

Population pharmacokinetics of amikacin in patients with haematological malignancies
J. Antimicrob. Chemother. 1999 44: 235-242; doi:10.1093/jac/44.2.235 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Thomas Butler, C. B. Sridhar, M. K. Daga, Kamal Pathak, R. B. Pandit, Rasik Khakhria, Chandrashekhar N. Potkar, Michael T. Zelasky, and Raymond B. Johnson

Treatment of typhoid fever with azithromycin versus chloramphenicol in a randomized multicentre trial in India
J. Antimicrob. Chemother. 1999 44: 243-250; doi:10.1093/jac/44.2.243 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

R. C. Moellering, P. K. Linden, J. Reinhardt, E. A. Blumberg, F. Bompart, and G.H. Talbot

The efficacy and safety of quinupristin/dalfopristin for the treatment of infections caused by vancomycin-resistant Enterococcus faecium
J. Antimicrob. Chemother. 1999 44: 251-261; doi:10.1093/jac/44.2.251 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ronald L. Nichols, Donald R. Graham, Steven L. Barriere, Anthony Rodgers, Samuel E. Wilson, Marcus Zervos, David L. Dunn, and Bruce Kreter

Treatment of hospitalized patients with complicated Gram-positive skin and skin structure infections: two randomized, multicentre studies of quinupristin/dalfopristin versus cefazolin, oxacillin or vancomycin
J. Antimicrob. Chemother. 1999 44: 263-273; doi:10.1093/jac/44.2.263 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

H. Vorbach, B. Robibaro, C. Armbruster, M. Atteneder, M. Reiter, M. Hlousek, R. Schaumann, and A. Georgopoulos

Endothelial cell compatibility of clindamycin, gentamicin, ceftriaxone and teicoplanin in Bier's arterial arrest
J. Antimicrob. Chemother. 1999 44: 275-277; doi:10.1093/jac/44.2.275 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

B. Randhawa, E. B. Harris, and K. Prabhakaran

Bactericidal action of oral ampicillin/sulbactam against Mycobacterium leprae
J. Antimicrob. Chemother. 1999 44: 279-281; doi:10.1093/jac/44.2.279 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Gema Ramos, Manuel Cuenca-Estrella, Araceli Monzón, and Juan L. Rodríguez-Tudela

In-vitro comparative activity of UR-9825, itraconazole and fluconazole against clinical isolates of Candida spp.
J. Antimicrob. Chemother. 1999 44: 283-286; doi:10.1093/jac/44.2.283 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ulla-Stina Salminen, Timo U. T. Viljanen, Ville V. Valtonen, Timo E. H. Ikonen, Antero E. Sahlman, and Ari L. J. Harjula

Ceftriaxone versus vancomycin prophylaxis in cardiovascular surgery
J. Antimicrob. Chemother. 1999 44: 287-290; doi:10.1093/jac/44.2.287 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

Pramod M. Shah

Personalized antifungal susceptibility testing
J. Antimicrob. Chemother. 1999 44: 291; doi:10.1093/jac/44.2.291 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Tanittha Chatsuwan and Sebastian G. B. Amyes

Setting the standard for determining the in-vitro susceptibility of Helicobacter pylori to metronidazole
J. Antimicrob. Chemother. 1999 44: 291a-293a; doi:10.1093/jac/44.2.291a [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Ian C. Carmichael, Valerie Godfrey, and Gary Nicholson

Errors associated with determining the susceptibilities of staphylococci to trimethoprim by the Vitek GPS-AK card
J. Antimicrob. Chemother. 1999 44: 293-294; doi:10.1093/jac/44.2.293 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Vitali Sintchenko, Peter J. Jelfs, William K. Chew, and Gwendolyn L. Gilbert

Mycobacterium tuberculosis rpoB gene DNA sequencing: implications for detection of rifamycin resistance
J. Antimicrob. Chemother. 1999 44: 294-295; doi:10.1093/jac/44.2.294 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Susan L. Pendland, Karen J. Losnedahl, and Christopher A. Schriever

In-vitro activity of gatifloxacin, a novel fluoroquinolone, compared with that of ciprofloxacin against Legionella spp.
J. Antimicrob. Chemother. 1999 44: 295-297; doi:10.1093/jac/44.2.295 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Chad R. Messick, Susan L. Pendland, Majid Moshirfar, Richard G. Fiscella, Karen J. Losnedahl, Christopher A. Schriever, and Paul C. Schreckenberger

In-vitro activity of polyhexamethylene biguanide (PHMB) against fungal isolates associated with infective keratitis
J. Antimicrob. Chemother. 1999 44: 297-298; doi:10.1093/jac/44.2.297 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

M. Österblad, E. Kilpi, A. Hakanen, L. Palmu, and P. Huovinen

Antimicrobial resistance levels of enterobacteria isolated from minced meat
J. Antimicrob. Chemother. 1999 44: 298-299; doi:10.1093/jac/44.2.298 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

N. H. O'Connell, E. G. Smyth, C. Marshall, and H. Humphreys

Continuing high prevalence of methicillin resistance amongst Staphylococcus aureus blood culture isolates
J. Antimicrob. Chemother. 1999 44: 300; doi:10.1093/jac/44.2.300 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

H. R. N. Marona, J.A.S. Zuanazzi, and E. E.S. Schapoval

Determination of sparfloxacin and its degradation products by HPLC-PDA
J. Antimicrob. Chemother. 1999 44: 301-302; doi:10.1093/jac/44.2.301 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Book reviews:

Robert S. Heyderman

Emerging Infections (Biomedical Research Reports)
J. Antimicrob. Chemother. 1999 44: 303; doi:10.1093/jac/44.2.303 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Timothy R. Walsh

Molecular Bacteriology: Protocols and Clinical Application
J. Antimicrob. Chemother. 1999 44: 303a-304a; doi:10.1093/jac/44.2.303a [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Timothy R. Walsh

Antibacterial Peptide Protocols (Methods in Molecular Biology Volume 78)
J. Antimicrob. Chemother. 1999 44: 304-305; doi:10.1093/jac/44.2.304 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

P. Venkatesan

Antimicrobial Therapy and Vaccines
J. Antimicrob. Chemother. 1999 44: 305; doi:10.1093/jac/44.2.305 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Erratum:

Luis Martínez-Martínez, Felipe Fernández, and Evelio J. Perea

Relationship between haemolysis production and resistance to fluoroquinolones among clinical isolates of Escherichia coli
J. Antimicrob. Chemother. 1999 44: 307. [Extract] [FREE Full Text] [Request Permissions]  

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