Journal of Antimicrobial Chemotherapy

Leading articles:

Lee Ann Thal and Marcus J. Zervos

Occurrence and epidemiology of resistance to virginiamycin and streptogramins
J. Antimicrob. Chemother. 1999 43: 171-176; doi:10.1093/jac/43.2.171 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Reviews:

E. Bergogne-Bérézin and A. Bryskier

The suppository form of antibiotic administration: pharmacokinetics and clinical application
J. Antimicrob. Chemother. 1999 43: 177-185; doi:10.1093/jac/43.2.177 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Kenji Marumo, Atsushi Takeda, Yoshiko Nakamura, and Kazuyasu Nakaya

Detection of OXA-4 ß-lactamase in Pseudomonas aeruginosa isolates by genetic methods
J. Antimicrob. Chemother. 1999 43: 187-193; doi:10.1093/jac/43.2.187 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Anindya Sundar Ghosh, Alak Kanti Kar, and Manikuntala Kundu

Impaired imipenem uptake associated with alterations in outer membrane proteins and lipopolysaccharides in imipenem-resistant Shigella dysenteriae
J. Antimicrob. Chemother. 1999 43: 195-201; doi:10.1093/jac/43.2.195 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

S. M. McAllister, H. O. Alpar, and M. R. W. Brown

Antimicrobial properties of liposomal polymyxin B
J. Antimicrob. Chemother. 1999 43: 203-210; doi:10.1093/jac/43.2.203 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Franz Allerberger and Ingo Klare

In-vitro activity of fosfomycin against vancomycin-resistant enterococci
J. Antimicrob. Chemother. 1999 43: 211-217; doi:10.1093/jac/43.2.211 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Nikki M. Parrish, Francis P. Kuhajda, Henry S. Heine, William R. Bishai, and James D. Dick

Antimycobacterial activity of cerulenin and its effects on lipid biosynthesis
J. Antimicrob. Chemother. 1999 43: 219-226; doi:10.1093/jac/43.2.219 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

A. Favel, F. Peyron, M. De Méo, A. Michel-Nguyen, J. Carrière, C. Chastin, and P. Regli

Amphotericin B susceptibility testing of Candida lusitaniae isolates by flow cytofluorometry: comparison with the Etest and the NCCLS broth macrodilution method
J. Antimicrob. Chemother. 1999 43: 227-232; doi:10.1093/jac/43.2.227 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Takeshi Nabe, Hideki Yamamura, Masakazu Hatanaka, Naoki Shinoda, Kaname Shimizu, Nobuaki Mizutani, Kazunori Yamashita, Michiaki Horiba, and Shigekatsu Kohno

Ability of teicoplanin and vancomycin to induce contraction of, and histamine release from, pulmonary tissue of humans, monkeys and guinea pigs
J. Antimicrob. Chemother. 1999 43: 233-242; doi:10.1093/jac/43.2.233 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Kari Grave, Egil Lingaas, Marit Bangen, and Marit Rønning

Surveillance of the overall consumption of antibacterial drugs in humans, domestic animals and farmed fish in Norway in 1992 and 1996
J. Antimicrob. Chemother. 1999 43: 243-252; doi:10.1093/jac/43.2.243 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Franz-Josef Schmitz, Ad C. Fluit, Mechthild Gondolf, Ralf Beyrau, Elke Lindenlauf, Jan Verhoef, Hans-Peter Heinz, and Mark E. Jones

The prevalence of aminoglycoside resistance and corresponding resistance genes in clinical isolates of staphylococci from 19 European hospitals
J. Antimicrob. Chemother. 1999 43: 253-259; doi:10.1093/jac/43.2.253 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Susan J. Bradley, Angela L. T. Wilson, Michael C. Allen, Hilary A. Sher, Anthony H. Goldstone, and Geoffrey M. Scott

The control of hyperendemic glycopeptide-resistant Enterococcus spp. on a haematology unit by changing antibiotic usage
J. Antimicrob. Chemother. 1999 43: 261-266; doi:10.1093/jac/43.2.261 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Andrew D. Luber, Lucy Maa, Minh Lam, and B. Joseph Guglielmo

Risk factors for amphotericin B- induced nephrotoxicity
J. Antimicrob. Chemother. 1999 43: 267-271; doi:10.1093/jac/43.2.267 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

R. Edwards, C. V. Hawkyard, M. T. Garvey, and D. Greenwood

Prevalence and degree of expression of the carbapenemase gene (cfiA) among clinical isolates of Bacteroides fragilis in Nottingham, UK
J. Antimicrob. Chemother. 1999 43: 273-276; doi:10.1093/jac/43.2.273 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Luis Martínez-Martínez, Felipe Fernández, and Evelio J. Perea

Relationship between haemolysis production and resistance to fluoroquinolones among clinical isolates of Escherichia coli
J. Antimicrob. Chemother. 1999 43: 277-279; doi:10.1093/jac/43.2.277 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Miho Fukuda, Hironobu Koga, Hideaki Ohno, Bing Yang, Yoichi Hirakata, Shigefumi Maesaki, Kazunori Tomono, Takayoshi Tashiro, and Shigeru Kohno

Relationship between genetic alteration of the rpsL gene and streptomycin susceptibility of Mycobacterium tuberculosis in Japan
J. Antimicrob. Chemother. 1999 43: 281-284; doi:10.1093/jac/43.2.281 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ricardo Fernández-Roblas, Raquel Calvo, Jaime Esteban, André Bryskier, and Francisco Soriano

The bactericidal activities of HMR 3004, HMR 3647 and erythromycin against Gram-positive bacilli and development of resistance
J. Antimicrob. Chemother. 1999 43: 285-289; doi:10.1093/jac/43.2.285 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

M. Bergeret and J. Raymond

In-vitro bactericidal activity of cefpirome and cefamandole in combination with glycopeptides against methicillin-resistant Staphylococcus aureus
J. Antimicrob. Chemother. 1999 43: 291-294; doi:10.1093/jac/43.2.291 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Francesco Barchiesi, Anna Maria Tortorano, Luigi Falconi Di Francesco, Massimo Cogliati, Giorgio Scalise, and Maria Anna Viviani

In-vitro activity of five antifungal agents against uncommon clinical isolates of Candida spp.
J. Antimicrob. Chemother. 1999 43: 295-299; doi:10.1093/jac/43.2.295 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Carlo Contini, Elena Angelici, and Rita Canipari

Structural changes in rat Pneumocystis cariniisurface antigens after terbinafine administration in experimental P. carinii pneumonia
J. Antimicrob. Chemother. 1999 43: 301-304; doi:10.1093/jac/43.2.301 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

G. Arredondo, E. Suárez, R. Calvo, J. A. Vazquez, J. García-Sanchez, and R. Martinez-Jordá

Serum protein binding of itraconazole and fluconazole in patients with diabetes mellitus
J. Antimicrob. Chemother. 1999 43: 305-307; doi:10.1093/jac/43.2.305 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

J. Lipman, C. D. Gomersall, T. Gin, G. M. Joynt, and R. J. Young

Continuous infusion ceftazidime in intensive care: a randomized controlled trial
J. Antimicrob. Chemother. 1999 43: 309-311; doi:10.1093/jac/43.2.309 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

Alan J. Hedges

The influence of factors affecting the `critical population' density of inocula on the determination of bacterial susceptibility to antibiotics by disc diffusion methods
J. Antimicrob. Chemother. 1999 43: 313; doi:10.1093/jac/43.2.313 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

A. Galloway, J. Wright, O. Murphy, and G. Dickinson

Sensitivity testing of Pseudomonas aeruginosa to ciprofloxacin: comparison of the modified Stokes' method with MIC results obtained by the Etest
J. Antimicrob. Chemother. 1999 43: 314-315; doi:10.1093/jac/43.2.314 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

S. Abell, S. Chapman, L. Nadin, and R. Warren

Seasonal variation in fluoroquinolone prescribing
J. Antimicrob. Chemother. 1999 43: 315-316; doi:10.1093/jac/43.2.315 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Paul E. Marik

Retraction: The failure of a once-daily vancomycin dosing regimen in patients with normal renal function
J. Antimicrob. Chemother. 1999 43: 316; doi:10.1093/jac/43.2.316 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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