Journal of Antimicrobial Chemotherapy

Leading articles:

Peter M. Bennett

Integrons and gene cassettes: a genetic construction kit for bacteria
J. Antimicrob. Chemother. 1999 43: 1-4; doi:10.1093/jac/43.1.1 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Original articles:

Whasun O. Chung, Christiane Werckenthin, Stefan Schwarz, and Marilyn C. Roberts

Host range of the ermF rRNA methylase gene in bacteria of human and animal origin
J. Antimicrob. Chemother. 1999 43: 5-14; doi:10.1093/jac/43.1.5 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Timothy M. A. Weller

The distribution of mecA, mecR1 and mecI and sequence analysis of mecI and the mec promoter region in staphylococci expressing resistance to methicillin
J. Antimicrob. Chemother. 1999 43: 15-22; doi:10.1093/jac/43.1.15 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Panagiota Giakkoupi, Eva Tzelepi, Nicholas J. Legakis, and Leonidas S. Tzouvelekis

Aspartic acid for asparagine substitution at position 276 reduces susceptibility to mechanism-based inhibitors in SHV-1 and SHV-5 ß-lactamases
J. Antimicrob. Chemother. 1999 43: 23-29; doi:10.1093/jac/43.1.23 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

O. Manzor, J. Pawlak, and L. Saravolatz

In-vitro activity of 29 antimicrobial agents against penicillin-resistant and -intermediate isolates of Streptococcus pneumoniae
J. Antimicrob. Chemother. 1999 43: 31-36; doi:10.1093/jac/43.1.31 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ingo Stock and Bernd Wiedemann

An in-vitro study of the antimicrobial susceptibilities of Yersinia enterocolitica and the definition of a database
J. Antimicrob. Chemother. 1999 43: 37-45; doi:10.1093/jac/43.1.37 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Maria P. Dore, Michael S. Osato, Giuseppe Realdi, Ida Mura, David Y. Graham, and Antonia R. Sepulveda

Amoxycillin tolerance in Helicobacter pylori
J. Antimicrob. Chemother. 1999 43: 47-54; doi:10.1093/jac/43.1.47 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Wai C. Chan, Ronald C. Li, Julia M. Ling, Augustine F. Cheng, and Jerome J. Schentag

Markedly different rates and resistance profiles exhibited by seven commonly used and newer ß-lactams on the selection of resistant variants of Enterobacter cloacae
J. Antimicrob. Chemother. 1999 43: 55-60; doi:10.1093/jac/43.1.55 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Laura J. V. Piddock, Y.-F. Jin, V. Ricci, and Anne E. Asuquo

Quinolone accumulation by Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli
J. Antimicrob. Chemother. 1999 43: 61-70; doi:10.1093/jac/43.1.61 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Fiona M. MacKenzie, Kathleen E. Milne, and Ian M. Gould

The post-exposure response of Enterobacteriaceae to ceftibuten
J. Antimicrob. Chemother. 1999 43: 71-77; doi:10.1093/jac/43.1.71 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Philip D. Lister and Christine C. Sanders

Pharmacodynamics of levofloxacin and ciprofloxacin against Streptococcus pneumoniae
J. Antimicrob. Chemother. 1999 43: 79-86; doi:10.1093/jac/43.1.79 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

F. Trostdorf, R. R. Reinert, H. Schmidt, T. Nichterlein, K. Stuertz, M. Schmitz-Salue, I. Sadowski, W. Brück, and R. Nau

Quinupristin/dalfopristin attenuates the inflammatory response and reduces the concentration of neuron-specific enolase in the cerebrospinal fluid of rabbits with experimental Streptococcus pneumoniae meningitis
J. Antimicrob. Chemother. 1999 43: 87-94; doi:10.1093/jac/43.1.87 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Andreas H. Groll, Corina E. Gonzalez, Neelam Giri, Krystina Kligys, William Love, Joanne Peter, Erwin Feuerstein, John Bacher, Stephen C. Piscitelli, and Thomas J. Walsh

Liposomal nystatin against experimental pulmonary aspergillosis in persistently neutropenic rabbits: efficacy, safety and non-compartmental pharmacokinetics
J. Antimicrob. Chemother. 1999 43: 95-103; doi:10.1093/jac/43.1.95 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Peter Davey, Ann-Marie Craig, Cathy Hau, and Mo Malek

Cost-effectiveness of prophylactic nasal mupirocin in patients undergoing peritoneal dialysis based on a randomized, placebo-controlled trial
J. Antimicrob. Chemother. 1999 43: 105-112; doi:10.1093/jac/43.1.105 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Karin Leder, John D. Turnidge, Tony M . Korman, and M. Lindsay Grayson

The clinical efficacy of continuous-infusion flucloxacillin in serious staphylococcal sepsis
J. Antimicrob. Chemother. 1999 43: 113-118; doi:10.1093/jac/43.1.113 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Gitte Pedersen, Henrik Carl Schønheyder, Flemming Hald Steffensen, and Henrik Toft Sørenson

Risk of resistance related to antibiotic use before admission in patients with community-acquired bacteraemia
J. Antimicrob. Chemother. 1999 43: 119-126; doi:10.1093/jac/43.1.119 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Brief reports:

Mariya Afzal-Shah, Hugo E. Villar, and David M. Livermore

Biochemical characteristics of a carbapenemase from an Acinetobacter baumannii isolate collected in Buenos Aires, Argentina
J. Antimicrob. Chemother. 1999 43: 127-131; doi:10.1093/jac/43.1.127 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Carmen Betriu, Ana Sánchez, Mara Gómez, M. Luisa Palau, and Juan J. Picazo

In-vitro susceptibilities of species of the Bacteroides fragilis group to newer ß -lactam agents
J. Antimicrob. Chemother. 1999 43: 133-136; doi:10.1093/jac/43.1.133 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Peter C. Fuchs, Arthur L. Barry, and Steven D. Brown

Fosfomycin tromethamine susceptibility of outpatient urine isolates of Escherichia coli and Enterococcus faecalisfrom ten North American medical centres by three methods
J. Antimicrob. Chemother. 1999 43: 137-140; doi:10.1093/jac/43.1.137 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

J. M. Andrews, J. P. Ashby, and R. Wise

Study to assess the reliability of a disc diffusion method for determining the sensitivity of Gram-positive pathogens to dalfopristin/quinupristin
J. Antimicrob. Chemother. 1999 43: 141-143; doi:10.1093/jac/43.1.141 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Antti Hakanen, Anja Siitonen, Pirkko Kotilainen, and Pentti Huovinen

Increasing fluoroquinolone resistance in salmonella serotypes in Finland during 1995–1997
J. Antimicrob. Chemother. 1999 43: 145-148; doi:10.1093/jac/43.1.145 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Manuel Cuenca-Estrella, Beatriz Ruiz-Díez, Joaquín V. Martínez-Suárez, Araceli Monzón, and Juan L. Rodríguez-Tudela

Comparative in-vitro activity of voriconazole (UK-109,496) and six other antifungal agents against clinical isolates of Scedosporium prolificans and Scedosporium apiospermum
J. Antimicrob. Chemother. 1999 43: 149-151; doi:10.1093/jac/43.1.149 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

D. Honeybourne, J. M. Andrews, B. Cunningham, G. Jevons, and R. Wise

The concentrations of clinafloxacin in alveolar macrophages, epithelial lining fluid, bronchial mucosa and serum after administration of single 200 mg oral doses to patients undergoing fibre-optic bronchoscopy
J. Antimicrob. Chemother. 1999 43: 153-155; doi:10.1093/jac/43.1.153 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Correspondence:

L. Poirel, A. Karim, A. Mercat, I. Le Thomas, H. Vahaboglu, C. Richard, and P. Nordmann

Extended-spectrum ß-lactamase-producing strain of Acinetobacter baumannii isolated from a patient in France
J. Antimicrob. Chemother. 1999 43: 157-158; doi:10.1093/jac/43.1.157 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

J. M. Schierholz, J. Beuth, and G. Pulverer

Adherent bacteria and activity of antibiotics
J. Antimicrob. Chemother. 1999 43: 158-160; doi:10.1093/jac/43.1.158 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

A. P. Johnson, D. James, and D. M. Livermore

Increasing prevalence of methicillin resistance amongst Staphylococcus aureus blood culture isolates
J. Antimicrob. Chemother. 1999 43: 160; doi:10.1093/jac/43.1.160 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

R. M. Bannatyne, Z. A. Memish, and M. C. Jackson

Correlation between serotype and in-vitro antibiotic susceptibility of pneumococci isolated in Saudi Arabia
J. Antimicrob. Chemother. 1999 43: 161-162; doi:10.1093/jac/43.1.161 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

I. Foley, P. Marsh, E. M. H. Wellington, A. W. Smith, and M. R. W. Brown

General stress response master regulator rpoS is expressed in human infection: a possible role in chronicity
J. Antimicrob. Chemother. 1999 43: 164-165; doi:10.1093/jac/43.1.164 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Book reviews:

P. Cowling

Medical Microbiology and Infectious Diseases, 2nd edn
J. Antimicrob. Chemother. 1999 43: 167; doi:10.1093/jac/43.1.167 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

A. P. Fraise

Essential Procedures for Clinical Microbiology
J. Antimicrob. Chemother. 1999 43: 167a-168a; doi:10.1093/jac/43.1.167A [Extract] [FREE Full Text] [PDF] [Request Permissions]  

P. Cane

Molecular Virology, 2nd edn
J. Antimicrob. Chemother. 1999 43: 168; doi:10.1093/jac/43.1.168 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

D. Pillay

Antiviral Therapy
J. Antimicrob. Chemother. 1999 43: 168a; doi:10.1093/jac/43.1.168A [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Corrigendum:

E. Sakagawa, M. Otsuki, T. Oh, and T. Nishino

In-vitro and in-vivo antibacterial activities of CS-834, a new oral carbapenem
J. Antimicrob. Chemother. 1999 43: 169. [Extract] [FREE Full Text] [PDF] [Request Permissions]  

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